2IK8B

Crystal structure of the heterodimeric complex of human rgs16 and activated gi alpha 1
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
120
structure length
120
Chain Sequence
SFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(i), alpha-1 subunit
molecule tags Signaling protein
source organism Homo sapiens
total genus 42
structure length 120
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ik8B02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ik8B01
5DO9B 2OWIA 4PNKA 1EMUA 3PVWA 3NYOA 3C7LA 3PVUA 4EKDB 1CMZA 2JM5A 1AGRE 3KRWA 2AF0A 3NYNA 4TNDA 2JNUA 2BT2A 1EZYA 2OJ4A 1FQIA 3CIKA 2GTPC 1OMWA 1FQJB 5HE0A 2DLVA 5HE2A 2CRPA 2IK8B 4TNBA 2EBZA 1EZTA 3UZTA 5HE1A 3PSCA 2ODEB 3V5WA 2V4ZB 1DK8A 5HE3A 2D9JA 2IHBB 4MK0A 2BCJA 1FQKB 3KRXA 2IHDA 3C7KB 2BV1A
chains in the Genus database with same CATH superfamily
5DO9B 2OWIA 4PNKA 1EMUA 3PVWA 3NYOA 3C7LA 3PVUA 4EKDB 1CMZA 2JM5A 1AGRE 3KRWA 2AF0A 3NYNA 4TNDA 2JNUA 2BT2A 1EZYA 2OJ4A 1FQIA 3CIKA 2GTPC 1OMWA 1FQJB 5HE0A 4HTEA 2DLVA 5HE2A 2CRPA 2IK8B 4TNBA 2EBZA 1EZTA 3UZTA 5HE1A 3PSCA 3QYFA 2ODEB 3V5WA 2V4ZB 1DK8A 5HE3A 2D9JA 2IHBB 4MK0A 3I5QA 2BCJA 1FQKB 3KRXA 2IHDA 3C7KB 2BV1A 5REQB
chains in the Genus database with same CATH topology
5DO9B 2OWIA 4PNKA 1EMUA 3PVWA 3NYOA 3C7LA 3PVUA 4EKDB 1CMZA 2JM5A 1AGRE 3KRWA 2AF0A 3NYNA 4TNDA 2JNUA 2BT2A 1EZYA 2OJ4A 1FQIA 3CIKA 2GTPC 1OMWA 1FQJB 5HE0A 2DLVA 5HE2A 2CRPA 2IK8B 4TNBA 2EBZA 1EZTA 3UZTA 5HE1A 3PSCA 3QYFA 2ODEB 3V5WA 2V4ZB 1DK8A 5HE3A 2D9JA 2IHBB 4MK0A 2BCJA 1FQKB 3KRXA 2IHDA 3C7KB 2BV1A 5REQB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DO9 B;  2OWI A;  4PNK A;  1EMU A;  3PVW A;  3NYO A;  3C7L A;  3PVU A;  4EKD B;  1CMZ A;  2JM5 A;  1AGR E;  3KRW A;  2AF0 A;  3NYN A;  4TND A;  2JNU A;  2BT2 A;  1EZY A;  2OJ4 A;  1FQI A;  3CIK A;  2GTP C;  1OMW A;  1FQJ B;  5HE0 A;  2DLV A;  5HE2 A;  2CRP A;  2IK8 B;  4TNB A;  2EBZ A;  1EZT A;  3UZT A;  5HE1 A;  3PSC A;  2ODE B;  3V5W A;  2V4Z B;  1DK8 A;  5HE3 A;  2D9J A;  2IHB B;  4MK0 A;  2BCJ A;  1FQK B;  3KRX A;  2IHD A;  3C7K B;  2BV1 A; 
#chains in the Genus database with same CATH topology
 5DO9 B;  2OWI A;  4PNK A;  1EMU A;  3PVW A;  3NYO A;  3C7L A;  3PVU A;  4EKD B;  1CMZ A;  2JM5 A;  1AGR E;  3KRW A;  2AF0 A;  3NYN A;  4TND A;  2JNU A;  2BT2 A;  1EZY A;  2OJ4 A;  1FQI A;  3CIK A;  2GTP C;  1OMW A;  1FQJ B;  5HE0 A;  4HTE A;  2DLV A;  5HE2 A;  2CRP A;  2IK8 B;  4TNB A;  2EBZ A;  1EZT A;  3UZT A;  5HE1 A;  3PSC A;  3QYF A;  2ODE B;  3V5W A;  2V4Z B;  1DK8 A;  5HE3 A;  2D9J A;  2IHB B;  4MK0 A;  3I5Q A;  2BCJ A;  1FQK B;  3KRX A;  2IHD A;  3C7K B;  2BV1 A;  5REQ B; 
#chains in the Genus database with same CATH homology
 5DO9 B;  2OWI A;  4PNK A;  1EMU A;  3PVW A;  3NYO A;  3C7L A;  3PVU A;  4EKD B;  1CMZ A;  2JM5 A;  1AGR E;  3KRW A;  2AF0 A;  3NYN A;  4TND A;  2JNU A;  2BT2 A;  1EZY A;  2OJ4 A;  1FQI A;  3CIK A;  2GTP C;  1OMW A;  1FQJ B;  5HE0 A;  2DLV A;  5HE2 A;  2CRP A;  2IK8 B;  4TNB A;  2EBZ A;  1EZT A;  3UZT A;  5HE1 A;  3PSC A;  3QYF A;  2ODE B;  3V5W A;  2V4Z B;  1DK8 A;  5HE3 A;  2D9J A;  2IHB B;  4MK0 A;  2BCJ A;  1FQK B;  3KRX A;  2IHD A;  3C7K B;  2BV1 A;  5REQ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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