2JM5A

Solution structure of the rgs domain from human rgs18
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
134
structure length
134
Chain Sequence
SMVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 18
total genus 50
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2006-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jm5A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jm5A01
3PSCA 2JM5A 1AGRE 5DO9B 4PNKA 3UZTA 3NYNA 2GTPC 4EKDB 1FQIA 2ODEB 2BV1A 2IHBB 1OMWA 3KRXA 5HE0A 3C7KB 2BCJA 3CIKA 2IHDA 5HE2A 2V4ZB 2IK8B 3NYOA 3PVUA 3V5WA 5HE1A 1EMUA 2DLVA 3PVWA 2OJ4A 4TNBA 4MK0A 1EZTA 2EBZA 1DK8A 2JNUA 3KRWA 1CMZA 2OWIA 2CRPA 2D9JA 4TNDA 1FQJB 3C7LA 1EZYA 5HE3A 1FQKB 2BT2A 2AF0A
chains in the Genus database with same CATH superfamily
3PSCA 2JM5A 1AGRE 5DO9B 4PNKA 3UZTA 3NYNA 2GTPC 3QYFA 4HTEA 4EKDB 1FQIA 5REQB 2ODEB 2BV1A 2IHBB 1OMWA 3KRXA 5HE0A 3C7KB 2BCJA 3CIKA 2IHDA 5HE2A 2V4ZB 2IK8B 3NYOA 3PVUA 3V5WA 5HE1A 1EMUA 2DLVA 3PVWA 2OJ4A 4TNBA 4MK0A 1EZTA 2EBZA 1DK8A 2JNUA 3KRWA 1CMZA 2OWIA 2CRPA 2D9JA 4TNDA 1FQJB 3C7LA 1EZYA 3I5QA 5HE3A 1FQKB 2BT2A 2AF0A
chains in the Genus database with same CATH topology
3PSCA 2JM5A 1AGRE 5DO9B 4PNKA 3UZTA 3NYNA 2GTPC 3QYFA 4EKDB 1FQIA 5REQB 2ODEB 2BV1A 2IHBB 1OMWA 3KRXA 5HE0A 3C7KB 2BCJA 3CIKA 2IHDA 5HE2A 2V4ZB 2IK8B 3NYOA 3PVUA 3V5WA 5HE1A 1EMUA 2DLVA 3PVWA 2OJ4A 4TNBA 4MK0A 1EZTA 2EBZA 1DK8A 2JNUA 3KRWA 1CMZA 2OWIA 2CRPA 2D9JA 4TNDA 1FQJB 3C7LA 1EZYA 5HE3A 1FQKB 2BT2A 2AF0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PSC A;  2JM5 A;  1AGR E;  5DO9 B;  4PNK A;  3UZT A;  3NYN A;  2GTP C;  4EKD B;  1FQI A;  2ODE B;  2BV1 A;  2IHB B;  1OMW A;  3KRX A;  5HE0 A;  3C7K B;  2BCJ A;  3CIK A;  2IHD A;  5HE2 A;  2V4Z B;  2IK8 B;  3NYO A;  3PVU A;  3V5W A;  5HE1 A;  1EMU A;  2DLV A;  3PVW A;  2OJ4 A;  4TNB A;  4MK0 A;  1EZT A;  2EBZ A;  1DK8 A;  2JNU A;  3KRW A;  1CMZ A;  2OWI A;  2CRP A;  2D9J A;  4TND A;  1FQJ B;  3C7L A;  1EZY A;  5HE3 A;  1FQK B;  2BT2 A;  2AF0 A; 
#chains in the Genus database with same CATH topology
 3PSC A;  2JM5 A;  1AGR E;  5DO9 B;  4PNK A;  3UZT A;  3NYN A;  2GTP C;  3QYF A;  4HTE A;  4EKD B;  1FQI A;  5REQ B;  2ODE B;  2BV1 A;  2IHB B;  1OMW A;  3KRX A;  5HE0 A;  3C7K B;  2BCJ A;  3CIK A;  2IHD A;  5HE2 A;  2V4Z B;  2IK8 B;  3NYO A;  3PVU A;  3V5W A;  5HE1 A;  1EMU A;  2DLV A;  3PVW A;  2OJ4 A;  4TNB A;  4MK0 A;  1EZT A;  2EBZ A;  1DK8 A;  2JNU A;  3KRW A;  1CMZ A;  2OWI A;  2CRP A;  2D9J A;  4TND A;  1FQJ B;  3C7L A;  1EZY A;  3I5Q A;  5HE3 A;  1FQK B;  2BT2 A;  2AF0 A; 
#chains in the Genus database with same CATH homology
 3PSC A;  2JM5 A;  1AGR E;  5DO9 B;  4PNK A;  3UZT A;  3NYN A;  2GTP C;  3QYF A;  4EKD B;  1FQI A;  5REQ B;  2ODE B;  2BV1 A;  2IHB B;  1OMW A;  3KRX A;  5HE0 A;  3C7K B;  2BCJ A;  3CIK A;  2IHD A;  5HE2 A;  2V4Z B;  2IK8 B;  3NYO A;  3PVU A;  3V5W A;  5HE1 A;  1EMU A;  2DLV A;  3PVW A;  2OJ4 A;  4TNB A;  4MK0 A;  1EZT A;  2EBZ A;  1DK8 A;  2JNU A;  3KRW A;  1CMZ A;  2OWI A;  2CRP A;  2D9J A;  4TND A;  1FQJ B;  3C7L A;  1EZY A;  5HE3 A;  1FQK B;  2BT2 A;  2AF0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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