2JM5A

Solution structure of the rgs domain from human rgs18
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
134
structure length
134
Chain Sequence
SMVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLMEGRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 18
total genus 50
structure length 134
sequence length 134
ec nomenclature
pdb deposition date 2006-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jm5A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jm5A01
2BV1A 2JNUA 5HE3A 4TNDA 1EMUA 2EBZA 1AGRE 2IHBB 2OJ4A 3CIKA 3NYNA 4EKDB 2ODEB 1CMZA 1EZTA 1EZYA 3C7KB 1FQKB 2JM5A 3KRWA 5HE2A 4PNKA 5HE1A 3V5WA 3NYOA 2D9JA 5HE0A 2DLVA 2OWIA 1DK8A 1FQIA 2IK8B 2BT2A 3PVWA 4TNBA 2AF0A 3PSCA 5DO9B 1OMWA 4MK0A 3KRXA 1FQJB 2CRPA 2GTPC 3PVUA 2IHDA 3C7LA 3UZTA 2V4ZB 2BCJA
chains in the Genus database with same CATH superfamily
2BV1A 2JNUA 5HE3A 4TNDA 1EMUA 2EBZA 1AGRE 2IHBB 2OJ4A 3CIKA 3NYNA 4EKDB 2ODEB 1CMZA 1EZTA 1EZYA 5REQB 3C7KB 1FQKB 2JM5A 3KRWA 5HE2A 4PNKA 3QYFA 5HE1A 3V5WA 3NYOA 2D9JA 5HE0A 2DLVA 2OWIA 1DK8A 1FQIA 2IK8B 2BT2A 3PVWA 4TNBA 2AF0A 3PSCA 5DO9B 1OMWA 4MK0A 3I5QA 3KRXA 1FQJB 2CRPA 2GTPC 3PVUA 4HTEA 2IHDA 3C7LA 3UZTA 2V4ZB 2BCJA
chains in the Genus database with same CATH topology
2BV1A 2JNUA 5HE3A 4TNDA 1EMUA 2EBZA 1AGRE 2IHBB 2OJ4A 3CIKA 3NYNA 4EKDB 2ODEB 1CMZA 1EZTA 1EZYA 5REQB 3C7KB 1FQKB 2JM5A 3KRWA 5HE2A 4PNKA 3QYFA 5HE1A 3V5WA 3NYOA 2D9JA 5HE0A 2DLVA 2OWIA 1DK8A 1FQIA 2IK8B 2BT2A 3PVWA 4TNBA 2AF0A 3PSCA 5DO9B 1OMWA 4MK0A 3KRXA 1FQJB 2CRPA 2GTPC 3PVUA 2IHDA 3C7LA 3UZTA 2V4ZB 2BCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BV1 A;  2JNU A;  5HE3 A;  4TND A;  1EMU A;  2EBZ A;  1AGR E;  2IHB B;  2OJ4 A;  3CIK A;  3NYN A;  4EKD B;  2ODE B;  1CMZ A;  1EZT A;  1EZY A;  3C7K B;  1FQK B;  2JM5 A;  3KRW A;  5HE2 A;  4PNK A;  5HE1 A;  3V5W A;  3NYO A;  2D9J A;  5HE0 A;  2DLV A;  2OWI A;  1DK8 A;  1FQI A;  2IK8 B;  2BT2 A;  3PVW A;  4TNB A;  2AF0 A;  3PSC A;  5DO9 B;  1OMW A;  4MK0 A;  3KRX A;  1FQJ B;  2CRP A;  2GTP C;  3PVU A;  2IHD A;  3C7L A;  3UZT A;  2V4Z B;  2BCJ A; 
#chains in the Genus database with same CATH topology
 2BV1 A;  2JNU A;  5HE3 A;  4TND A;  1EMU A;  2EBZ A;  1AGR E;  2IHB B;  2OJ4 A;  3CIK A;  3NYN A;  4EKD B;  2ODE B;  1CMZ A;  1EZT A;  1EZY A;  5REQ B;  3C7K B;  1FQK B;  2JM5 A;  3KRW A;  5HE2 A;  4PNK A;  3QYF A;  5HE1 A;  3V5W A;  3NYO A;  2D9J A;  5HE0 A;  2DLV A;  2OWI A;  1DK8 A;  1FQI A;  2IK8 B;  2BT2 A;  3PVW A;  4TNB A;  2AF0 A;  3PSC A;  5DO9 B;  1OMW A;  4MK0 A;  3I5Q A;  3KRX A;  1FQJ B;  2CRP A;  2GTP C;  3PVU A;  4HTE A;  2IHD A;  3C7L A;  3UZT A;  2V4Z B;  2BCJ A; 
#chains in the Genus database with same CATH homology
 2BV1 A;  2JNU A;  5HE3 A;  4TND A;  1EMU A;  2EBZ A;  1AGR E;  2IHB B;  2OJ4 A;  3CIK A;  3NYN A;  4EKD B;  2ODE B;  1CMZ A;  1EZT A;  1EZY A;  5REQ B;  3C7K B;  1FQK B;  2JM5 A;  3KRW A;  5HE2 A;  4PNK A;  3QYF A;  5HE1 A;  3V5W A;  3NYO A;  2D9J A;  5HE0 A;  2DLV A;  2OWI A;  1DK8 A;  1FQI A;  2IK8 B;  2BT2 A;  3PVW A;  4TNB A;  2AF0 A;  3PSC A;  5DO9 B;  1OMW A;  4MK0 A;  3KRX A;  1FQJ B;  2CRP A;  2GTP C;  3PVU A;  2IHD A;  3C7L A;  3UZT A;  2V4Z B;  2BCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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