2JNUA

Solution structure of the rgs domain of human rgs14
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
136
structure length
136
Chain Sequence
SMTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
source organism Homo sapiens
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Regulator of G-protein signaling 14
total genus 35
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2007-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jnuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jnuA01
1EZTA 4PNKA 1OMWA 1EZYA 5HE3A 2GTPC 2IK8B 1FQJB 3NYNA 3PSCA 2IHDA 2V4ZB 2JNUA 1CMZA 2BT2A 2ODEB 4TNBA 3C7KB 1FQKB 3NYOA 3KRXA 2DLVA 4MK0A 1FQIA 1EMUA 3PVUA 5HE2A 2BV1A 5DO9B 3V5WA 4EKDB 3C7LA 1AGRE 2AF0A 2EBZA 3CIKA 2JM5A 5HE0A 2OJ4A 5HE1A 2D9JA 3PVWA 2IHBB 1DK8A 3KRWA 2BCJA 2CRPA 4TNDA 2OWIA 3UZTA
chains in the Genus database with same CATH superfamily
1EZTA 4PNKA 1OMWA 1EZYA 5HE3A 2GTPC 2IK8B 1FQJB 3NYNA 3PSCA 2IHDA 2V4ZB 2JNUA 1CMZA 2BT2A 3I5QA 2ODEB 4TNBA 3C7KB 1FQKB 3NYOA 3KRXA 2DLVA 4MK0A 1FQIA 1EMUA 3PVUA 5HE2A 2BV1A 5DO9B 3V5WA 4EKDB 3C7LA 1AGRE 2AF0A 2EBZA 3CIKA 2JM5A 5HE0A 2OJ4A 3QYFA 5HE1A 4HTEA 5REQB 2D9JA 3PVWA 2IHBB 1DK8A 3KRWA 2BCJA 2CRPA 4TNDA 2OWIA 3UZTA
chains in the Genus database with same CATH topology
1EZTA 4PNKA 1OMWA 1EZYA 5HE3A 2GTPC 2IK8B 1FQJB 3NYNA 3PSCA 2IHDA 2V4ZB 2JNUA 1CMZA 2BT2A 2ODEB 4TNBA 3C7KB 1FQKB 3NYOA 3KRXA 2DLVA 4MK0A 1FQIA 1EMUA 3PVUA 5HE2A 2BV1A 5DO9B 3V5WA 4EKDB 3C7LA 1AGRE 2AF0A 2EBZA 3CIKA 2JM5A 5HE0A 2OJ4A 3QYFA 5HE1A 5REQB 2D9JA 3PVWA 2IHBB 1DK8A 3KRWA 2BCJA 2CRPA 4TNDA 2OWIA 3UZTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZT A;  4PNK A;  1OMW A;  1EZY A;  5HE3 A;  2GTP C;  2IK8 B;  1FQJ B;  3NYN A;  3PSC A;  2IHD A;  2V4Z B;  2JNU A;  1CMZ A;  2BT2 A;  2ODE B;  4TNB A;  3C7K B;  1FQK B;  3NYO A;  3KRX A;  2DLV A;  4MK0 A;  1FQI A;  1EMU A;  3PVU A;  5HE2 A;  2BV1 A;  5DO9 B;  3V5W A;  4EKD B;  3C7L A;  1AGR E;  2AF0 A;  2EBZ A;  3CIK A;  2JM5 A;  5HE0 A;  2OJ4 A;  5HE1 A;  2D9J A;  3PVW A;  2IHB B;  1DK8 A;  3KRW A;  2BCJ A;  2CRP A;  4TND A;  2OWI A;  3UZT A; 
#chains in the Genus database with same CATH topology
 1EZT A;  4PNK A;  1OMW A;  1EZY A;  5HE3 A;  2GTP C;  2IK8 B;  1FQJ B;  3NYN A;  3PSC A;  2IHD A;  2V4Z B;  2JNU A;  1CMZ A;  2BT2 A;  3I5Q A;  2ODE B;  4TNB A;  3C7K B;  1FQK B;  3NYO A;  3KRX A;  2DLV A;  4MK0 A;  1FQI A;  1EMU A;  3PVU A;  5HE2 A;  2BV1 A;  5DO9 B;  3V5W A;  4EKD B;  3C7L A;  1AGR E;  2AF0 A;  2EBZ A;  3CIK A;  2JM5 A;  5HE0 A;  2OJ4 A;  3QYF A;  5HE1 A;  4HTE A;  5REQ B;  2D9J A;  3PVW A;  2IHB B;  1DK8 A;  3KRW A;  2BCJ A;  2CRP A;  4TND A;  2OWI A;  3UZT A; 
#chains in the Genus database with same CATH homology
 1EZT A;  4PNK A;  1OMW A;  1EZY A;  5HE3 A;  2GTP C;  2IK8 B;  1FQJ B;  3NYN A;  3PSC A;  2IHD A;  2V4Z B;  2JNU A;  1CMZ A;  2BT2 A;  2ODE B;  4TNB A;  3C7K B;  1FQK B;  3NYO A;  3KRX A;  2DLV A;  4MK0 A;  1FQI A;  1EMU A;  3PVU A;  5HE2 A;  2BV1 A;  5DO9 B;  3V5W A;  4EKD B;  3C7L A;  1AGR E;  2AF0 A;  2EBZ A;  3CIK A;  2JM5 A;  5HE0 A;  2OJ4 A;  3QYF A;  5HE1 A;  5REQ B;  2D9J A;  3PVW A;  2IHB B;  1DK8 A;  3KRW A;  2BCJ A;  2CRP A;  4TND A;  2OWI A;  3UZT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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