2JNUA

Solution structure of the rgs domain of human rgs14
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
136
structure length
136
Chain Sequence
SMTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule keywords Regulator of G-protein signaling 14
molecule tags Signaling protein
source organism Homo sapiens
total genus 35
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 2007-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2jnuA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2jnuA01
2BV1A 3NYOA 4TNDA 2BT2A 2V4ZB 4TNBA 3C7LA 2IHDA 3PVUA 2ODEB 1EZTA 5DO9B 1AGRE 2AF0A 4MK0A 1FQJB 3KRXA 2JM5A 3C7KB 5HE0A 2IK8B 2EBZA 3NYNA 4EKDB 1OMWA 1FQKB 3V5WA 1CMZA 1DK8A 2OJ4A 5HE3A 2IHBB 1FQIA 2CRPA 3UZTA 2BCJA 3CIKA 2JNUA 1EZYA 3PVWA 2DLVA 3PSCA 4PNKA 2GTPC 3KRWA 1EMUA 2D9JA 5HE2A 5HE1A 2OWIA
chains in the Genus database with same CATH superfamily
2BV1A 3NYOA 4TNDA 2BT2A 2V4ZB 4TNBA 3C7LA 2IHDA 3PVUA 2ODEB 1EZTA 5DO9B 1AGRE 2AF0A 4MK0A 1FQJB 3KRXA 2JM5A 4HTEA 3C7KB 5REQB 5HE0A 2IK8B 2EBZA 3NYNA 4EKDB 1OMWA 1FQKB 3V5WA 1CMZA 1DK8A 2OJ4A 3QYFA 5HE3A 2IHBB 1FQIA 2CRPA 3UZTA 2BCJA 3CIKA 2JNUA 1EZYA 3PVWA 2DLVA 3PSCA 4PNKA 2GTPC 3KRWA 1EMUA 2D9JA 5HE2A 3I5QA 5HE1A 2OWIA
chains in the Genus database with same CATH topology
2BV1A 3NYOA 4TNDA 2BT2A 2V4ZB 4TNBA 3C7LA 2IHDA 3PVUA 2ODEB 1EZTA 5DO9B 1AGRE 2AF0A 4MK0A 1FQJB 3KRXA 2JM5A 3C7KB 5REQB 5HE0A 2IK8B 2EBZA 3NYNA 4EKDB 1OMWA 1FQKB 3V5WA 1CMZA 1DK8A 2OJ4A 3QYFA 5HE3A 2IHBB 1FQIA 2CRPA 3UZTA 2BCJA 3CIKA 2JNUA 1EZYA 3PVWA 2DLVA 3PSCA 4PNKA 2GTPC 3KRWA 1EMUA 2D9JA 5HE2A 5HE1A 2OWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BV1 A;  3NYO A;  4TND A;  2BT2 A;  2V4Z B;  4TNB A;  3C7L A;  2IHD A;  3PVU A;  2ODE B;  1EZT A;  5DO9 B;  1AGR E;  2AF0 A;  4MK0 A;  1FQJ B;  3KRX A;  2JM5 A;  3C7K B;  5HE0 A;  2IK8 B;  2EBZ A;  3NYN A;  4EKD B;  1OMW A;  1FQK B;  3V5W A;  1CMZ A;  1DK8 A;  2OJ4 A;  5HE3 A;  2IHB B;  1FQI A;  2CRP A;  3UZT A;  2BCJ A;  3CIK A;  2JNU A;  1EZY A;  3PVW A;  2DLV A;  3PSC A;  4PNK A;  2GTP C;  3KRW A;  1EMU A;  2D9J A;  5HE2 A;  5HE1 A;  2OWI A; 
#chains in the Genus database with same CATH topology
 2BV1 A;  3NYO A;  4TND A;  2BT2 A;  2V4Z B;  4TNB A;  3C7L A;  2IHD A;  3PVU A;  2ODE B;  1EZT A;  5DO9 B;  1AGR E;  2AF0 A;  4MK0 A;  1FQJ B;  3KRX A;  2JM5 A;  4HTE A;  3C7K B;  5REQ B;  5HE0 A;  2IK8 B;  2EBZ A;  3NYN A;  4EKD B;  1OMW A;  1FQK B;  3V5W A;  1CMZ A;  1DK8 A;  2OJ4 A;  3QYF A;  5HE3 A;  2IHB B;  1FQI A;  2CRP A;  3UZT A;  2BCJ A;  3CIK A;  2JNU A;  1EZY A;  3PVW A;  2DLV A;  3PSC A;  4PNK A;  2GTP C;  3KRW A;  1EMU A;  2D9J A;  5HE2 A;  3I5Q A;  5HE1 A;  2OWI A; 
#chains in the Genus database with same CATH homology
 2BV1 A;  3NYO A;  4TND A;  2BT2 A;  2V4Z B;  4TNB A;  3C7L A;  2IHD A;  3PVU A;  2ODE B;  1EZT A;  5DO9 B;  1AGR E;  2AF0 A;  4MK0 A;  1FQJ B;  3KRX A;  2JM5 A;  3C7K B;  5REQ B;  5HE0 A;  2IK8 B;  2EBZ A;  3NYN A;  4EKD B;  1OMW A;  1FQK B;  3V5W A;  1CMZ A;  1DK8 A;  2OJ4 A;  3QYF A;  5HE3 A;  2IHB B;  1FQI A;  2CRP A;  3UZT A;  2BCJ A;  3CIK A;  2JNU A;  1EZY A;  3PVW A;  2DLV A;  3PSC A;  4PNK A;  2GTP C;  3KRW A;  1EMU A;  2D9J A;  5HE2 A;  5HE1 A;  2OWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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