2OJ4A

Crystal structure of rgs3 rgs domain
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
127
structure length
127
Chain Sequence
SEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
pubmed doi rcsb
molecule tags Signaling protein inhibitor
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 3
total genus 50
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2oj4A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2oj4A01
1EZYA 2JM5A 1CMZA 2BV1A 3CIKA 2GTPC 1FQIA 2V4ZB 2CRPA 2ODEB 2JNUA 4MK0A 1EMUA 2IK8B 3UZTA 2IHBB 3NYOA 4TNDA 2D9JA 1OMWA 2BCJA 2AF0A 3PSCA 1FQKB 1EZTA 3C7LA 3C7KB 4PNKA 5HE1A 4TNBA 1FQJB 4EKDB 3KRXA 5HE0A 5DO9B 5HE3A 5HE2A 1DK8A 2IHDA 1AGRE 3PVWA 3V5WA 3NYNA 2BT2A 3KRWA 2OJ4A 2OWIA 2EBZA 3PVUA 2DLVA
chains in the Genus database with same CATH superfamily
1EZYA 2JM5A 1CMZA 2BV1A 3CIKA 2GTPC 1FQIA 2V4ZB 2CRPA 2ODEB 2JNUA 4MK0A 1EMUA 2IK8B 3UZTA 2IHBB 3NYOA 4TNDA 2D9JA 1OMWA 2BCJA 3QYFA 2AF0A 3I5QA 3PSCA 1FQKB 1EZTA 3C7LA 3C7KB 4PNKA 5HE1A 4TNBA 1FQJB 4EKDB 4HTEA 3KRXA 5HE0A 5DO9B 5HE3A 5HE2A 1DK8A 2IHDA 1AGRE 3PVWA 3V5WA 3NYNA 2BT2A 3KRWA 2OJ4A 2OWIA 2EBZA 5REQB 3PVUA 2DLVA
chains in the Genus database with same CATH topology
1EZYA 2JM5A 1CMZA 2BV1A 3CIKA 2GTPC 1FQIA 2V4ZB 2CRPA 2ODEB 2JNUA 4MK0A 1EMUA 2IK8B 3UZTA 2IHBB 3NYOA 4TNDA 2D9JA 1OMWA 2BCJA 3QYFA 2AF0A 3PSCA 1FQKB 1EZTA 3C7LA 3C7KB 4PNKA 5HE1A 4TNBA 1FQJB 4EKDB 3KRXA 5HE0A 5DO9B 5HE3A 5HE2A 1DK8A 2IHDA 1AGRE 3PVWA 3V5WA 3NYNA 2BT2A 3KRWA 2OJ4A 2OWIA 2EBZA 5REQB 3PVUA 2DLVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZY A;  2JM5 A;  1CMZ A;  2BV1 A;  3CIK A;  2GTP C;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  2JNU A;  4MK0 A;  1EMU A;  2IK8 B;  3UZT A;  2IHB B;  3NYO A;  4TND A;  2D9J A;  1OMW A;  2BCJ A;  2AF0 A;  3PSC A;  1FQK B;  1EZT A;  3C7L A;  3C7K B;  4PNK A;  5HE1 A;  4TNB A;  1FQJ B;  4EKD B;  3KRX A;  5HE0 A;  5DO9 B;  5HE3 A;  5HE2 A;  1DK8 A;  2IHD A;  1AGR E;  3PVW A;  3V5W A;  3NYN A;  2BT2 A;  3KRW A;  2OJ4 A;  2OWI A;  2EBZ A;  3PVU A;  2DLV A; 
#chains in the Genus database with same CATH topology
 1EZY A;  2JM5 A;  1CMZ A;  2BV1 A;  3CIK A;  2GTP C;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  2JNU A;  4MK0 A;  1EMU A;  2IK8 B;  3UZT A;  2IHB B;  3NYO A;  4TND A;  2D9J A;  1OMW A;  2BCJ A;  3QYF A;  2AF0 A;  3I5Q A;  3PSC A;  1FQK B;  1EZT A;  3C7L A;  3C7K B;  4PNK A;  5HE1 A;  4TNB A;  1FQJ B;  4EKD B;  4HTE A;  3KRX A;  5HE0 A;  5DO9 B;  5HE3 A;  5HE2 A;  1DK8 A;  2IHD A;  1AGR E;  3PVW A;  3V5W A;  3NYN A;  2BT2 A;  3KRW A;  2OJ4 A;  2OWI A;  2EBZ A;  5REQ B;  3PVU A;  2DLV A; 
#chains in the Genus database with same CATH homology
 1EZY A;  2JM5 A;  1CMZ A;  2BV1 A;  3CIK A;  2GTP C;  1FQI A;  2V4Z B;  2CRP A;  2ODE B;  2JNU A;  4MK0 A;  1EMU A;  2IK8 B;  3UZT A;  2IHB B;  3NYO A;  4TND A;  2D9J A;  1OMW A;  2BCJ A;  3QYF A;  2AF0 A;  3PSC A;  1FQK B;  1EZT A;  3C7L A;  3C7K B;  4PNK A;  5HE1 A;  4TNB A;  1FQJ B;  4EKD B;  3KRX A;  5HE0 A;  5DO9 B;  5HE3 A;  5HE2 A;  1DK8 A;  2IHD A;  1AGR E;  3PVW A;  3V5W A;  3NYN A;  2BT2 A;  3KRW A;  2OJ4 A;  2OWI A;  2EBZ A;  5REQ B;  3PVU A;  2DLV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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