2QFBA

Crystal structure of the regulatory domain of human rig-i with bound zn
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 23
structure length 121
sequence length 121
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2007-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2qfbA00
3ZD7A 3EQTA 2RQAA 2RMJA 5F9FA 4AY2A 4BPBA 5F9HA 2QFDA 5E3HA 2YKGA 4A2XA 3LRNA 3NCUA 4A2VA 2QFBA 2RQBA 3LRRA 3GA3A 5F98A 2W4RA 3ZD6A 3OG8A
chains in the Genus database with same CATH superfamily
3ZD7A 1H6QA 2FU5A 4V2YA 3EQTA 4V2ZA 2RMJA 2RQAA 1HXRA 5F9FA 4AY2A 3CEZA 3FACA 4CI3B 5AMHA 4BPBA 3WX2A 5F9HA 2QFDA 5E3HA 2LOYA 2KV1A 2K8DA 3E0MA 2YKGA 2KWBA 1YZ1A 3CXKA 2KZNA 4A2XA 4V30A 3LRNA 3NCUA 4V31A 1H7YA 1TXJA 3HCIA 4A2VA 2QFBA 3MAOA 2RQBA 3LRRA 3HCHA 2LVLA 3WX1A 3GA3A 3HCJA 4TZCA 4CI2B 1L1DA 1FWQA 3HCGA 3P3KA 4TZUA 4TZ4C 4CI1B 5F98A 3DJMA 3EBMA 3E0OA 2W4RA 3ZD6A 3OG8A 2HR9A
chains in the Genus database with same CATH topology
3ZD7A 1H6QA 2FU5A 3EQTA 2RMJA 2RQAA 1HXRA 5F9FA 4AY2A 3FACA 4BPBA 5F9HA 2QFDA 5E3HA 2LOYA 2YKGA 2KWBA 1YZ1A 4A2XA 3LRNA 3NCUA 1H7YA 1TXJA 4A2VA 2QFBA 2RQBA 3LRRA 2LVLA 3GA3A 1FWQA 3P3KA 5F98A 3DJMA 3EBMA 2W4RA 3ZD6A 3OG8A 2HR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZD7 A;  3EQT A;  2RQA A;  2RMJ A;  5F9F A;  4AY2 A;  4BPB A;  5F9H A;  2QFD A;  5E3H A;  2YKG A;  4A2X A;  3LRN A;  3NCU A;  4A2V A;  2QFB A;  2RQB A;  3LRR A;  3GA3 A;  5F98 A;  2W4R A;  3ZD6 A;  3OG8 A; 
#chains in the Genus database with same CATH topology
 3ZD7 A;  1H6Q A;  2FU5 A;  4V2Y A;  3EQT A;  4V2Z A;  2RMJ A;  2RQA A;  1HXR A;  5F9F A;  4AY2 A;  3CEZ A;  3FAC A;  4CI3 B;  5AMH A;  4BPB A;  3WX2 A;  5F9H A;  2QFD A;  5E3H A;  2LOY A;  2KV1 A;  2K8D A;  3E0M A;  2YKG A;  2KWB A;  1YZ1 A;  3CXK A;  2KZN A;  4A2X A;  4V30 A;  3LRN A;  3NCU A;  4V31 A;  1H7Y A;  1TXJ A;  3HCI A;  4A2V A;  2QFB A;  3MAO A;  2RQB A;  3LRR A;  3HCH A;  2LVL A;  3WX1 A;  3GA3 A;  3HCJ A;  4TZC A;  4CI2 B;  1L1D A;  1FWQ A;  3HCG A;  3P3K A;  4TZU A;  4TZ4 C;  4CI1 B;  5F98 A;  3DJM A;  3EBM A;  3E0O A;  2W4R A;  3ZD6 A;  3OG8 A;  2HR9 A; 
#chains in the Genus database with same CATH homology
 3ZD7 A;  1H6Q A;  2FU5 A;  3EQT A;  2RMJ A;  2RQA A;  1HXR A;  5F9F A;  4AY2 A;  3FAC A;  4BPB A;  5F9H A;  2QFD A;  5E3H A;  2LOY A;  2YKG A;  2KWB A;  1YZ1 A;  4A2X A;  3LRN A;  3NCU A;  1H7Y A;  1TXJ A;  4A2V A;  2QFB A;  2RQB A;  3LRR A;  2LVL A;  3GA3 A;  1FWQ A;  3P3K A;  5F98 A;  3DJM A;  3EBM A;  2W4R A;  3ZD6 A;  3OG8 A;  2HR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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