2QFDA

Crystal structure of the regulatory domain of human rig-i with bound hg
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 23
structure length 121
sequence length 121
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2007-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2qfdA00
2RMJA 4A2XA 3ZD7A 5F98A 3LRNA 2RQBA 3OG8A 5E3HA 4BPBA 5F9HA 3EQTA 3LRRA 4A2VA 2YKGA 3GA3A 2QFDA 2QFBA 3ZD6A 3NCUA 4AY2A 2RQAA 2W4RA 5F9FA
chains in the Genus database with same CATH superfamily
2KV1A 2RMJA 4A2XA 2KZNA 3MAOA 3ZD7A 4V2ZA 3HCIA 4CI1B 3FACA 4TZUA 3LRNA 3WX2A 2RQBA 3P3KA 5F98A 1H7YA 3OG8A 4TZCA 5E3HA 3WX1A 2HR9A 4BPBA 5F9HA 3EQTA 3LRRA 2FU5A 4V2YA 4A2VA 2YKGA 3DJMA 2LVLA 3EBMA 3GA3A 4TZ4C 1L1DA 2KWBA 2QFDA 1YZ1A 1TXJA 3HCHA 4V31A 1FWQA 2QFBA 3ZD6A 2K8DA 3CEZA 4CI2B 2LOYA 3E0OA 5AMHA 3NCUA 4AY2A 1H6QA 4CI3B 3E0MA 3CXKA 2RQAA 2W4RA 4V30A 3HCJA 1HXRA 5F9FA 3HCGA
chains in the Genus database with same CATH topology
2RMJA 4A2XA 3ZD7A 5F98A 3FACA 3LRNA 2RQBA 3P3KA 1H7YA 3OG8A 5E3HA 2HR9A 4BPBA 5F9HA 3EQTA 3LRRA 2FU5A 4A2VA 2YKGA 3DJMA 3EBMA 2LVLA 3GA3A 2KWBA 2QFDA 1YZ1A 1TXJA 1FWQA 2QFBA 3ZD6A 2LOYA 3NCUA 4AY2A 1H6QA 2RQAA 2W4RA 1HXRA 5F9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RMJ A;  4A2X A;  3ZD7 A;  5F98 A;  3LRN A;  2RQB A;  3OG8 A;  5E3H A;  4BPB A;  5F9H A;  3EQT A;  3LRR A;  4A2V A;  2YKG A;  3GA3 A;  2QFD A;  2QFB A;  3ZD6 A;  3NCU A;  4AY2 A;  2RQA A;  2W4R A;  5F9F A; 
#chains in the Genus database with same CATH topology
 2KV1 A;  2RMJ A;  4A2X A;  2KZN A;  3MAO A;  3ZD7 A;  4V2Z A;  3HCI A;  4CI1 B;  3FAC A;  4TZU A;  3LRN A;  3WX2 A;  2RQB A;  3P3K A;  5F98 A;  1H7Y A;  3OG8 A;  4TZC A;  5E3H A;  3WX1 A;  2HR9 A;  4BPB A;  5F9H A;  3EQT A;  3LRR A;  2FU5 A;  4V2Y A;  4A2V A;  2YKG A;  3DJM A;  2LVL A;  3EBM A;  3GA3 A;  4TZ4 C;  1L1D A;  2KWB A;  2QFD A;  1YZ1 A;  1TXJ A;  3HCH A;  4V31 A;  1FWQ A;  2QFB A;  3ZD6 A;  2K8D A;  3CEZ A;  4CI2 B;  2LOY A;  3E0O A;  5AMH A;  3NCU A;  4AY2 A;  1H6Q A;  4CI3 B;  3E0M A;  3CXK A;  2RQA A;  2W4R A;  4V30 A;  3HCJ A;  1HXR A;  5F9F A;  3HCG A; 
#chains in the Genus database with same CATH homology
 2RMJ A;  4A2X A;  3ZD7 A;  5F98 A;  3FAC A;  3LRN A;  2RQB A;  3P3K A;  1H7Y A;  3OG8 A;  5E3H A;  2HR9 A;  4BPB A;  5F9H A;  3EQT A;  3LRR A;  2FU5 A;  4A2V A;  2YKG A;  3DJM A;  3EBM A;  2LVL A;  3GA3 A;  2KWB A;  2QFD A;  1YZ1 A;  1TXJ A;  1FWQ A;  2QFB A;  3ZD6 A;  2LOY A;  3NCU A;  4AY2 A;  1H6Q A;  2RQA A;  2W4R A;  1HXR A;  5F9F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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