2QPPA

Crystal structure of human heme oxygenase-2 c127a (ho-2) with bound heme
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
214
structure length
214
Chain Sequence
RMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQAPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Heme oxygenase 2
total genus 84
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2007-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 2qppA00
3IBXA 4LQXA 1TO9A 1S8CA 1J02A 4MECA 4G7PA 1P3UA 1XK0A 1OZLA 1WOVA 3I9TA 4WX0A 3BJDA 1WZFA 4NY7A 1OZWA 1WZDA 1OTVA 4G7UA 4WMHA 1YAFA 2QCXA 1S13A 1TWRA 4G98A 4GPCA 2RD3A 3HMLA 1P3VA 4GPFA 2QZCA 1UDDA 1TO9B 1J77A 1RCWA 1OZEA 4G8WA 1RTWA 1IW0A 2QPPA 4WWJA 1OYKA 1NI6A 1DVEA 1ULXA 3MVUA 1IX3A 1TWNA 1XK1A 3HOKA 2GM7A 1N3UA 3I9UA 4WWZA 1UBBA 1J2CA 3OQLA 1WOXA 1XK2A 4WD4A 1N45A 3MOOA 1YAKA 2F2GA 3NO6A 4G7TA 2A2MA 2GM8A 1WNWA 3CZYA 3HLXA 1IW1A 1P3TA 3B5PA 3TGMA 1WNVA 1WNXA 1T5PA 4GOHA 1WOWA 1OYLA 1Z72A 4G99A 1SK7A 4G7LA 1V8XA 2Q4XA 2Z68A 1XK3A 2A6BA 2DY5A 1IX4A 1IVJA 1OTWA 2Q32A 1DVGA 3DDEA 5BTQA 4G8PA 1WZGA 1XJZA 1WWMA 1TYHA 1IRMA 4RAJA 3B5OA 1OZRA 2RGZA 2A2OA 3HNHA 4FN6A 1WE1A 2ZVUA 4GPHA 3I8RA 4G8UA 2E7EA 3RM5A 1VGIA 3K4FA
chains in the Genus database with same CATH superfamily
3IBXA 4LQXA 1TO9A 1S8CA 1J02A 4MECA 2LCUA 4G7PA 1P3UA 1XK0A 1OZLA 1WOVA 3I9TA 4WX0A 3BJDA 1WZFA 4NY7A 1OZWA 1WZDA 1OTVA 4G7UA 4WMHA 1YAFA 2QCXA 1S13A 1TWRA 4G98A 4GPCA 2RD3A 3HMLA 1P3VA 4GPFA 2QZCA 1UDDA 1TO9B 1J77A 1RCWA 1OZEA 4G8WA 1RTWA 1IW0A 2QPPA 4WWJA 1OYKA 1NI6A 1DVEA 1ULXA 3MVUA 1IX3A 1TWNA 1XK1A 3HOKA 2GM7A 1N3UA 3I9UA 4WWZA 1UBBA 1J2CA 3OQLA 1WOXA 1XK2A 4WD4A 1N45A 3MOOA 1YAKA 2F2GA 3NO6A 4G7TA 2A2MA 2GM8A 1WNWA 3CZYA 3HLXA 1IW1A 1P3TA 3B5PA 3TGMA 1WNVA 1WNXA 1T5PA 4GOHA 1WOWA 1OYLA 1Z72A 4G99A 1SK7A 4G7LA 1V8XA 2Q4XA 2Z68A 1XK3A 2A6BA 2DY5A 1IX4A 1IVJA 1OTWA 2Q32A 1DVGA 3DDEA 5BTQA 4G8PA 1WZGA 1XJZA 1WWMA 1TYHA 1IRMA 4RAJA 3B5OA 1OZRA 2RGZA 2A2OA 3HNHA 4FN6A 1WE1A 2ZVUA 4GPHA 3I8RA 4G8UA 2E7EA 3RM5A 1VGIA 3K4FA
chains in the Genus database with same CATH topology
3IBXA 4LQXA 1TO9A 1S8CA 1J02A 4MECA 4G7PA 1P3UA 1XK0A 1OZLA 1WOVA 3I9TA 4WX0A 3BJDA 1WZFA 4NY7A 1OZWA 1WZDA 1OTVA 4G7UA 4WMHA 1YAFA 2QCXA 1S13A 1TWRA 4G98A 4GPCA 2RD3A 3HMLA 1P3VA 4GPFA 2QZCA 1UDDA 1TO9B 1J77A 1RCWA 1OZEA 4G8WA 1RTWA 1IW0A 2QPPA 4WWJA 1OYKA 1NI6A 1DVEA 1ULXA 3MVUA 1IX3A 1TWNA 1XK1A 3HOKA 2GM7A 1N3UA 3I9UA 4WWZA 1UBBA 1J2CA 3OQLA 1WOXA 1XK2A 4WD4A 1N45A 3MOOA 1YAKA 2F2GA 3NO6A 4G7TA 2A2MA 2GM8A 1WNWA 3CZYA 3HLXA 1IW1A 1P3TA 3B5PA 3TGMA 1WNVA 1WNXA 1T5PA 4GOHA 1WOWA 1OYLA 1Z72A 4G99A 1SK7A 4G7LA 1V8XA 2Q4XA 2Z68A 1XK3A 2A6BA 2DY5A 1IX4A 1IVJA 1OTWA 2Q32A 1DVGA 3DDEA 5BTQA 4G8PA 1WZGA 1XJZA 1WWMA 1TYHA 1IRMA 4RAJA 3B5OA 1OZRA 2RGZA 2A2OA 3HNHA 4FN6A 1WE1A 2ZVUA 4GPHA 3I8RA 4G8UA 2E7EA 3RM5A 1VGIA 3K4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IBX A;  4LQX A;  1TO9 A;  1S8C A;  1J02 A;  4MEC A;  4G7P A;  1P3U A;  1XK0 A;  1OZL A;  1WOV A;  3I9T A;  4WX0 A;  3BJD A;  1WZF A;  4NY7 A;  1OZW A;  1WZD A;  1OTV A;  4G7U A;  4WMH A;  1YAF A;  2QCX A;  1S13 A;  1TWR A;  4G98 A;  4GPC A;  2RD3 A;  3HML A;  1P3V A;  4GPF A;  2QZC A;  1UDD A;  1TO9 B;  1J77 A;  1RCW A;  1OZE A;  4G8W A;  1RTW A;  1IW0 A;  2QPP A;  4WWJ A;  1OYK A;  1NI6 A;  1DVE A;  1ULX A;  3MVU A;  1IX3 A;  1TWN A;  1XK1 A;  3HOK A;  2GM7 A;  1N3U A;  3I9U A;  4WWZ A;  1UBB A;  1J2C A;  3OQL A;  1WOX A;  1XK2 A;  4WD4 A;  1N45 A;  3MOO A;  1YAK A;  2F2G A;  3NO6 A;  4G7T A;  2A2M A;  2GM8 A;  1WNW A;  3CZY A;  3HLX A;  1IW1 A;  1P3T A;  3B5P A;  3TGM A;  1WNV A;  1WNX A;  1T5P A;  4GOH A;  1WOW A;  1OYL A;  1Z72 A;  4G99 A;  1SK7 A;  4G7L A;  1V8X A;  2Q4X A;  2Z68 A;  1XK3 A;  2A6B A;  2DY5 A;  1IX4 A;  1IVJ A;  1OTW A;  2Q32 A;  1DVG A;  3DDE A;  5BTQ A;  4G8P A;  1WZG A;  1XJZ A;  1WWM A;  1TYH A;  1IRM A;  4RAJ A;  3B5O A;  1OZR A;  2RGZ A;  2A2O A;  3HNH A;  4FN6 A;  1WE1 A;  2ZVU A;  4GPH A;  3I8R A;  4G8U A;  2E7E A;  3RM5 A;  1VGI A;  3K4F A; 
#chains in the Genus database with same CATH topology
 3IBX A;  4LQX A;  1TO9 A;  1S8C A;  1J02 A;  4MEC A;  2LCU A;  4G7P A;  1P3U A;  1XK0 A;  1OZL A;  1WOV A;  3I9T A;  4WX0 A;  3BJD A;  1WZF A;  4NY7 A;  1OZW A;  1WZD A;  1OTV A;  4G7U A;  4WMH A;  1YAF A;  2QCX A;  1S13 A;  1TWR A;  4G98 A;  4GPC A;  2RD3 A;  3HML A;  1P3V A;  4GPF A;  2QZC A;  1UDD A;  1TO9 B;  1J77 A;  1RCW A;  1OZE A;  4G8W A;  1RTW A;  1IW0 A;  2QPP A;  4WWJ A;  1OYK A;  1NI6 A;  1DVE A;  1ULX A;  3MVU A;  1IX3 A;  1TWN A;  1XK1 A;  3HOK A;  2GM7 A;  1N3U A;  3I9U A;  4WWZ A;  1UBB A;  1J2C A;  3OQL A;  1WOX A;  1XK2 A;  4WD4 A;  1N45 A;  3MOO A;  1YAK A;  2F2G A;  3NO6 A;  4G7T A;  2A2M A;  2GM8 A;  1WNW A;  3CZY A;  3HLX A;  1IW1 A;  1P3T A;  3B5P A;  3TGM A;  1WNV A;  1WNX A;  1T5P A;  4GOH A;  1WOW A;  1OYL A;  1Z72 A;  4G99 A;  1SK7 A;  4G7L A;  1V8X A;  2Q4X A;  2Z68 A;  1XK3 A;  2A6B A;  2DY5 A;  1IX4 A;  1IVJ A;  1OTW A;  2Q32 A;  1DVG A;  3DDE A;  5BTQ A;  4G8P A;  1WZG A;  1XJZ A;  1WWM A;  1TYH A;  1IRM A;  4RAJ A;  3B5O A;  1OZR A;  2RGZ A;  2A2O A;  3HNH A;  4FN6 A;  1WE1 A;  2ZVU A;  4GPH A;  3I8R A;  4G8U A;  2E7E A;  3RM5 A;  1VGI A;  3K4F A; 
#chains in the Genus database with same CATH homology
 3IBX A;  4LQX A;  1TO9 A;  1S8C A;  1J02 A;  4MEC A;  4G7P A;  1P3U A;  1XK0 A;  1OZL A;  1WOV A;  3I9T A;  4WX0 A;  3BJD A;  1WZF A;  4NY7 A;  1OZW A;  1WZD A;  1OTV A;  4G7U A;  4WMH A;  1YAF A;  2QCX A;  1S13 A;  1TWR A;  4G98 A;  4GPC A;  2RD3 A;  3HML A;  1P3V A;  4GPF A;  2QZC A;  1UDD A;  1TO9 B;  1J77 A;  1RCW A;  1OZE A;  4G8W A;  1RTW A;  1IW0 A;  2QPP A;  4WWJ A;  1OYK A;  1NI6 A;  1DVE A;  1ULX A;  3MVU A;  1IX3 A;  1TWN A;  1XK1 A;  3HOK A;  2GM7 A;  1N3U A;  3I9U A;  4WWZ A;  1UBB A;  1J2C A;  3OQL A;  1WOX A;  1XK2 A;  4WD4 A;  1N45 A;  3MOO A;  1YAK A;  2F2G A;  3NO6 A;  4G7T A;  2A2M A;  2GM8 A;  1WNW A;  3CZY A;  3HLX A;  1IW1 A;  1P3T A;  3B5P A;  3TGM A;  1WNV A;  1WNX A;  1T5P A;  4GOH A;  1WOW A;  1OYL A;  1Z72 A;  4G99 A;  1SK7 A;  4G7L A;  1V8X A;  2Q4X A;  2Z68 A;  1XK3 A;  2A6B A;  2DY5 A;  1IX4 A;  1IVJ A;  1OTW A;  2Q32 A;  1DVG A;  3DDE A;  5BTQ A;  4G8P A;  1WZG A;  1XJZ A;  1WWM A;  1TYH A;  1IRM A;  4RAJ A;  3B5O A;  1OZR A;  2RGZ A;  2A2O A;  3HNH A;  4FN6 A;  1WE1 A;  2ZVU A;  4GPH A;  3I8R A;  4G8U A;  2E7E A;  3RM5 A;  1VGI A;  3K4F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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