2RQAA

Solution structure of lgp2 ctd
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
137
structure length
137
Chain Sequence
GPHMQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ATP-dependent RNA helicase DHX58
total genus 14
structure length 137
sequence length 137
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rqaA00
4A2XA 5E3HA 3LRNA 4A2VA 3NCUA 2RQAA 2QFBA 2RMJA 5F98A 4BPBA 2QFDA 2W4RA 3EQTA 5F9FA 2YKGA 3ZD6A 5F9HA 2RQBA 4AY2A 3ZD7A 3GA3A 3LRRA 3OG8A
chains in the Genus database with same CATH superfamily
1TXJA 3CEZA 4A2XA 3E0OA 3HCHA 2K8DA 2FU5A 1HXRA 3HCJA 4V2YA 2KV1A 3CXKA 5E3HA 3E0MA 4CI2B 3WX1A 3LRNA 4A2VA 3NCUA 4V2ZA 2RQAA 1H7YA 1L1DA 3HCIA 4CI3B 2QFBA 4CI1B 4TZUA 4V30A 2KZNA 3WX2A 2LOYA 2RMJA 5AMHA 3MAOA 1FWQA 4BPBA 5F98A 3DJMA 3EBMA 2QFDA 2W4RA 3EQTA 5F9FA 4V31A 4TZ4C 3HCGA 2YKGA 3ZD6A 5F9HA 2HR9A 1YZ1A 2LVLA 1H6QA 2RQBA 3P3KA 4AY2A 3ZD7A 3GA3A 2KWBA 3FACA 4TZCA 3LRRA 3OG8A
chains in the Genus database with same CATH topology
1TXJA 4A2XA 2FU5A 1HXRA 5E3HA 3LRNA 4A2VA 3NCUA 2RQAA 1H7YA 2QFBA 2LOYA 2RMJA 5F98A 1FWQA 4BPBA 3DJMA 3EBMA 2QFDA 2W4RA 3EQTA 5F9FA 2YKGA 3ZD6A 5F9HA 2HR9A 1YZ1A 2LVLA 1H6QA 2RQBA 3P3KA 4AY2A 3ZD7A 3GA3A 2KWBA 3FACA 3LRRA 3OG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A2X A;  5E3H A;  3LRN A;  4A2V A;  3NCU A;  2RQA A;  2QFB A;  2RMJ A;  5F98 A;  4BPB A;  2QFD A;  2W4R A;  3EQT A;  5F9F A;  2YKG A;  3ZD6 A;  5F9H A;  2RQB A;  4AY2 A;  3ZD7 A;  3GA3 A;  3LRR A;  3OG8 A; 
#chains in the Genus database with same CATH topology
 1TXJ A;  3CEZ A;  4A2X A;  3E0O A;  3HCH A;  2K8D A;  2FU5 A;  1HXR A;  3HCJ A;  4V2Y A;  2KV1 A;  3CXK A;  5E3H A;  3E0M A;  4CI2 B;  3WX1 A;  3LRN A;  4A2V A;  3NCU A;  4V2Z A;  2RQA A;  1H7Y A;  1L1D A;  3HCI A;  4CI3 B;  2QFB A;  4CI1 B;  4TZU A;  4V30 A;  2KZN A;  3WX2 A;  2LOY A;  2RMJ A;  5AMH A;  3MAO A;  1FWQ A;  4BPB A;  5F98 A;  3DJM A;  3EBM A;  2QFD A;  2W4R A;  3EQT A;  5F9F A;  4V31 A;  4TZ4 C;  3HCG A;  2YKG A;  3ZD6 A;  5F9H A;  2HR9 A;  1YZ1 A;  2LVL A;  1H6Q A;  2RQB A;  3P3K A;  4AY2 A;  3ZD7 A;  3GA3 A;  2KWB A;  3FAC A;  4TZC A;  3LRR A;  3OG8 A; 
#chains in the Genus database with same CATH homology
 1TXJ A;  4A2X A;  2FU5 A;  1HXR A;  5E3H A;  3LRN A;  4A2V A;  3NCU A;  2RQA A;  1H7Y A;  2QFB A;  2LOY A;  2RMJ A;  5F98 A;  1FWQ A;  4BPB A;  3DJM A;  3EBM A;  2QFD A;  2W4R A;  3EQT A;  5F9F A;  2YKG A;  3ZD6 A;  5F9H A;  2HR9 A;  1YZ1 A;  2LVL A;  1H6Q A;  2RQB A;  3P3K A;  4AY2 A;  3ZD7 A;  3GA3 A;  2KWB A;  3FAC A;  3LRR A;  3OG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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