2RQAA

Solution structure of lgp2 ctd
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
137
structure length
137
Chain Sequence
GPHMQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSDLSLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords ATP-dependent RNA helicase DHX58
total genus 14
structure length 137
sequence length 137
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rqaA00
2RMJA 5E3HA 5F9HA 3NCUA 2W4RA 4BPBA 3LRNA 3OG8A 2RQBA 4AY2A 4A2XA 3ZD6A 3GA3A 3LRRA 2QFBA 3EQTA 5F9FA 2YKGA 2QFDA 3ZD7A 4A2VA 2RQAA 5F98A
chains in the Genus database with same CATH superfamily
3P3KA 1H7YA 2RMJA 2KV1A 1TXJA 5E3HA 3WX1A 5F9HA 3HCIA 3WX2A 3NCUA 4TZCA 2KZNA 3HCJA 4TZ4C 2W4RA 3HCHA 4BPBA 1YZ1A 3LRNA 1FWQA 1HXRA 2K8DA 4V2YA 3OG8A 2RQBA 4AY2A 3FACA 4A2XA 3ZD6A 4V30A 4CI3B 2HR9A 3GA3A 2LVLA 3HCGA 4CI1B 3E0OA 3CEZA 3EBMA 3LRRA 2QFBA 4V31A 3EQTA 5F9FA 2KWBA 4TZUA 4V2ZA 5AMHA 2LOYA 2QFDA 4CI2B 2YKGA 3E0MA 3DJMA 1L1DA 3ZD7A 1H6QA 3CXKA 4A2VA 2RQAA 2FU5A 5F98A 3MAOA
chains in the Genus database with same CATH topology
3P3KA 1H7YA 2RMJA 5E3HA 1TXJA 5F9HA 3NCUA 2W4RA 4BPBA 1YZ1A 3LRNA 1FWQA 1HXRA 3OG8A 2RQBA 4AY2A 3FACA 4A2XA 3ZD6A 2HR9A 3GA3A 2LVLA 3EBMA 3LRRA 2QFBA 3EQTA 5F9FA 2KWBA 2YKGA 2LOYA 2QFDA 3ZD7A 3DJMA 1H6QA 4A2VA 2RQAA 2FU5A 5F98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RMJ A;  5E3H A;  5F9H A;  3NCU A;  2W4R A;  4BPB A;  3LRN A;  3OG8 A;  2RQB A;  4AY2 A;  4A2X A;  3ZD6 A;  3GA3 A;  3LRR A;  2QFB A;  3EQT A;  5F9F A;  2YKG A;  2QFD A;  3ZD7 A;  4A2V A;  2RQA A;  5F98 A; 
#chains in the Genus database with same CATH topology
 3P3K A;  1H7Y A;  2RMJ A;  2KV1 A;  1TXJ A;  5E3H A;  3WX1 A;  5F9H A;  3HCI A;  3WX2 A;  3NCU A;  4TZC A;  2KZN A;  3HCJ A;  4TZ4 C;  2W4R A;  3HCH A;  4BPB A;  1YZ1 A;  3LRN A;  1FWQ A;  1HXR A;  2K8D A;  4V2Y A;  3OG8 A;  2RQB A;  4AY2 A;  3FAC A;  4A2X A;  3ZD6 A;  4V30 A;  4CI3 B;  2HR9 A;  3GA3 A;  2LVL A;  3HCG A;  4CI1 B;  3E0O A;  3CEZ A;  3EBM A;  3LRR A;  2QFB A;  4V31 A;  3EQT A;  5F9F A;  2KWB A;  4TZU A;  4V2Z A;  5AMH A;  2LOY A;  2QFD A;  4CI2 B;  2YKG A;  3E0M A;  3DJM A;  1L1D A;  3ZD7 A;  1H6Q A;  3CXK A;  4A2V A;  2RQA A;  2FU5 A;  5F98 A;  3MAO A; 
#chains in the Genus database with same CATH homology
 3P3K A;  1H7Y A;  2RMJ A;  5E3H A;  1TXJ A;  5F9H A;  3NCU A;  2W4R A;  4BPB A;  1YZ1 A;  3LRN A;  1FWQ A;  1HXR A;  3OG8 A;  2RQB A;  4AY2 A;  3FAC A;  4A2X A;  3ZD6 A;  2HR9 A;  3GA3 A;  2LVL A;  3EBM A;  3LRR A;  2QFB A;  3EQT A;  5F9F A;  2KWB A;  2YKG A;  2LOY A;  2QFD A;  3ZD7 A;  3DJM A;  1H6Q A;  4A2V A;  2RQA A;  2FU5 A;  5F98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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