2RQBA

Solution structure of mda5 ctd
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
135
structure length
135
Chain Sequence
GPLGSYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Homo sapiens
publication title Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
pubmed doi rcsb
molecule keywords Interferon-induced helicase C domain-containing protein 1
total genus 12
structure length 135
sequence length 135
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rqbA00
2QFBA 3EQTA 3LRRA 2RQBA 2QFDA 2W4RA 3OG8A 5F9HA 2RMJA 3LRNA 5E3HA 4A2VA 5F9FA 4BPBA 4AY2A 5F98A 3NCUA 3GA3A 4A2XA 2RQAA 3ZD7A 2YKGA 3ZD6A
chains in the Genus database with same CATH superfamily
3HCJA 2QFBA 3EQTA 1TXJA 4CI3B 1H6QA 3E0OA 4V30A 3E0MA 1L1DA 3LRRA 2RQBA 4CI2B 1H7YA 2QFDA 3EBMA 4TZUA 4V2YA 2W4RA 3OG8A 1FWQA 4TZ4C 5F9HA 2RMJA 3WX1A 3HCGA 5AMHA 2K8DA 2FU5A 3LRNA 2LVLA 2KWBA 4A2VA 5E3HA 2HR9A 3DJMA 4TZCA 5F9FA 3P3KA 4CI1B 3HCHA 3FACA 4BPBA 4AY2A 5F98A 2KV1A 3NCUA 3CXKA 3GA3A 3MAOA 4V2ZA 4A2XA 3WX2A 1HXRA 2RQAA 3CEZA 4V31A 2LOYA 3HCIA 3ZD7A 1YZ1A 2YKGA 2KZNA 3ZD6A
chains in the Genus database with same CATH topology
2QFBA 3EQTA 1TXJA 1H6QA 3LRRA 2RQBA 1H7YA 3EBMA 2QFDA 2W4RA 3OG8A 1FWQA 5F9HA 2RMJA 2FU5A 3LRNA 2LVLA 2KWBA 4A2VA 5E3HA 2HR9A 3DJMA 5F9FA 3P3KA 3FACA 4BPBA 4AY2A 5F98A 3NCUA 3GA3A 4A2XA 1HXRA 2RQAA 3ZD7A 2LOYA 1YZ1A 2YKGA 3ZD6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QFB A;  3EQT A;  3LRR A;  2RQB A;  2QFD A;  2W4R A;  3OG8 A;  5F9H A;  2RMJ A;  3LRN A;  5E3H A;  4A2V A;  5F9F A;  4BPB A;  4AY2 A;  5F98 A;  3NCU A;  3GA3 A;  4A2X A;  2RQA A;  3ZD7 A;  2YKG A;  3ZD6 A; 
#chains in the Genus database with same CATH topology
 3HCJ A;  2QFB A;  3EQT A;  1TXJ A;  4CI3 B;  1H6Q A;  3E0O A;  4V30 A;  3E0M A;  1L1D A;  3LRR A;  2RQB A;  4CI2 B;  1H7Y A;  2QFD A;  3EBM A;  4TZU A;  4V2Y A;  2W4R A;  3OG8 A;  1FWQ A;  4TZ4 C;  5F9H A;  2RMJ A;  3WX1 A;  3HCG A;  5AMH A;  2K8D A;  2FU5 A;  3LRN A;  2LVL A;  2KWB A;  4A2V A;  5E3H A;  2HR9 A;  3DJM A;  4TZC A;  5F9F A;  3P3K A;  4CI1 B;  3HCH A;  3FAC A;  4BPB A;  4AY2 A;  5F98 A;  2KV1 A;  3NCU A;  3CXK A;  3GA3 A;  3MAO A;  4V2Z A;  4A2X A;  3WX2 A;  1HXR A;  2RQA A;  3CEZ A;  4V31 A;  2LOY A;  3HCI A;  3ZD7 A;  1YZ1 A;  2YKG A;  2KZN A;  3ZD6 A; 
#chains in the Genus database with same CATH homology
 2QFB A;  3EQT A;  1TXJ A;  1H6Q A;  3LRR A;  2RQB A;  1H7Y A;  3EBM A;  2QFD A;  2W4R A;  3OG8 A;  1FWQ A;  5F9H A;  2RMJ A;  2FU5 A;  3LRN A;  2LVL A;  2KWB A;  4A2V A;  5E3H A;  2HR9 A;  3DJM A;  5F9F A;  3P3K A;  3FAC A;  4BPB A;  4AY2 A;  5F98 A;  3NCU A;  3GA3 A;  4A2X A;  1HXR A;  2RQA A;  3ZD7 A;  2LOY A;  1YZ1 A;  2YKG A;  3ZD6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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