2W4RA

Crystal structure of the regulatory domain of human lgp2
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
131
structure length
125
Chain Sequence
RQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROBABLE ATP-DEPENDENT RNA HELICASE DHX58
total genus 21
structure length 125
sequence length 131
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2w4rA00
3OG8A 4A2VA 5E3HA 5F9FA 4AY2A 2QFBA 3LRNA 4A2XA 3ZD7A 2RQAA 2QFDA 3NCUA 5F9HA 2RMJA 3EQTA 4BPBA 2RQBA 3LRRA 5F98A 3GA3A 2W4RA 3ZD6A 2YKGA
chains in the Genus database with same CATH superfamily
4V31A 4V30A 2FU5A 3OG8A 3EQTA 2KZNA 4CI1B 4A2VA 1H6QA 3MAOA 5E3HA 2YKGA 5F9FA 3CXKA 4AY2A 2QFBA 3HCJA 3HCGA 3CEZA 3WX1A 3E0OA 4A2XA 3FACA 3HCHA 4CI3B 4V2ZA 1L1DA 3P3KA 4CI2B 5AMHA 2RQAA 3ZD7A 3EBMA 4V2YA 2QFDA 3NCUA 5F9HA 2RMJA 2KV1A 2LVLA 3HCIA 4TZUA 4TZ4C 2LOYA 1FWQA 1HXRA 2KWBA 2RQBA 3WX2A 2K8DA 4BPBA 3LRRA 1H7YA 1TXJA 3E0MA 5F98A 3ZD6A 3GA3A 2W4RA 1YZ1A 4TZCA 3LRNA 2HR9A 3DJMA
chains in the Genus database with same CATH topology
2FU5A 3OG8A 4A2VA 1H6QA 5E3HA 5F9FA 4AY2A 2QFBA 4A2XA 3FACA 3P3KA 3ZD7A 2RQAA 3EBMA 2QFDA 3NCUA 5F9HA 2RMJA 2LVLA 2YKGA 3EQTA 2LOYA 1FWQA 1HXRA 2KWBA 2RQBA 4BPBA 3LRRA 1H7YA 1TXJA 5F98A 3ZD6A 3GA3A 2W4RA 1YZ1A 3LRNA 2HR9A 3DJMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OG8 A;  4A2V A;  5E3H A;  5F9F A;  4AY2 A;  2QFB A;  3LRN A;  4A2X A;  3ZD7 A;  2RQA A;  2QFD A;  3NCU A;  5F9H A;  2RMJ A;  3EQT A;  4BPB A;  2RQB A;  3LRR A;  5F98 A;  3GA3 A;  2W4R A;  3ZD6 A;  2YKG A; 
#chains in the Genus database with same CATH topology
 4V31 A;  4V30 A;  2FU5 A;  3OG8 A;  3EQT A;  2KZN A;  4CI1 B;  4A2V A;  1H6Q A;  3MAO A;  5E3H A;  2YKG A;  5F9F A;  3CXK A;  4AY2 A;  2QFB A;  3HCJ A;  3HCG A;  3CEZ A;  3WX1 A;  3E0O A;  4A2X A;  3FAC A;  3HCH A;  4CI3 B;  4V2Z A;  1L1D A;  3P3K A;  4CI2 B;  5AMH A;  2RQA A;  3ZD7 A;  3EBM A;  4V2Y A;  2QFD A;  3NCU A;  5F9H A;  2RMJ A;  2KV1 A;  2LVL A;  3HCI A;  4TZU A;  4TZ4 C;  2LOY A;  1FWQ A;  1HXR A;  2KWB A;  2RQB A;  3WX2 A;  2K8D A;  4BPB A;  3LRR A;  1H7Y A;  1TXJ A;  3E0M A;  5F98 A;  3ZD6 A;  3GA3 A;  2W4R A;  1YZ1 A;  4TZC A;  3LRN A;  2HR9 A;  3DJM A; 
#chains in the Genus database with same CATH homology
 2FU5 A;  3OG8 A;  4A2V A;  1H6Q A;  5E3H A;  5F9F A;  4AY2 A;  2QFB A;  4A2X A;  3FAC A;  3P3K A;  3ZD7 A;  2RQA A;  3EBM A;  2QFD A;  3NCU A;  5F9H A;  2RMJ A;  2LVL A;  2YKG A;  3EQT A;  2LOY A;  1FWQ A;  1HXR A;  2KWB A;  2RQB A;  4BPB A;  3LRR A;  1H7Y A;  1TXJ A;  5F98 A;  3ZD6 A;  3GA3 A;  2W4R A;  1YZ1 A;  3LRN A;  2HR9 A;  3DJM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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