2W4RA

Crystal structure of the regulatory domain of human lgp2
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
131
structure length
125
Chain Sequence
RQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROBABLE ATP-DEPENDENT RNA HELICASE DHX58
total genus 21
structure length 125
sequence length 131
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2w4rA00
3GA3A 4BPBA 5F9FA 2RMJA 3ZD7A 5F98A 2W4RA 4A2XA 3NCUA 2QFDA 2YKGA 3ZD6A 2RQBA 2QFBA 4A2VA 5F9HA 3LRNA 5E3HA 4AY2A 2RQAA 3LRRA 3EQTA 3OG8A
chains in the Genus database with same CATH superfamily
4V2ZA 4V30A 4TZ4C 3GA3A 2KZNA 4BPBA 5F9FA 2LVLA 2KV1A 2RMJA 3ZD7A 3CEZA 4V31A 2W4RA 4CI1B 5F98A 1FWQA 3CXKA 1H6QA 3E0MA 4A2XA 1HXRA 3WX1A 4CI2B 3NCUA 3HCGA 2QFDA 4CI3B 2YKGA 1YZ1A 3ZD6A 3HCIA 3HCJA 2FU5A 4TZUA 2RQBA 3E0OA 2QFBA 3EBMA 3HCHA 3MAOA 4V2YA 4TZCA 3FACA 4A2VA 2LOYA 2K8DA 1L1DA 1TXJA 5E3HA 3LRNA 5F9HA 2RQAA 4AY2A 1H7YA 3LRRA 2KWBA 3P3KA 3DJMA 3WX2A 5AMHA 3EQTA 2HR9A 3OG8A
chains in the Genus database with same CATH topology
3GA3A 4BPBA 5F9FA 2LVLA 2RMJA 3ZD7A 5F98A 2W4RA 1FWQA 1H6QA 4A2XA 1HXRA 3NCUA 2QFDA 2YKGA 1YZ1A 3ZD6A 2FU5A 2RQBA 2QFBA 3EBMA 3FACA 4A2VA 2LOYA 1TXJA 5F9HA 5E3HA 3LRNA 4AY2A 2RQAA 1H7YA 3LRRA 2KWBA 3P3KA 3DJMA 3EQTA 2HR9A 3OG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GA3 A;  4BPB A;  5F9F A;  2RMJ A;  3ZD7 A;  5F98 A;  2W4R A;  4A2X A;  3NCU A;  2QFD A;  2YKG A;  3ZD6 A;  2RQB A;  2QFB A;  4A2V A;  5F9H A;  3LRN A;  5E3H A;  4AY2 A;  2RQA A;  3LRR A;  3EQT A;  3OG8 A; 
#chains in the Genus database with same CATH topology
 4V2Z A;  4V30 A;  4TZ4 C;  3GA3 A;  2KZN A;  4BPB A;  5F9F A;  2LVL A;  2KV1 A;  2RMJ A;  3ZD7 A;  3CEZ A;  4V31 A;  2W4R A;  4CI1 B;  5F98 A;  1FWQ A;  3CXK A;  1H6Q A;  3E0M A;  4A2X A;  1HXR A;  3WX1 A;  4CI2 B;  3NCU A;  3HCG A;  2QFD A;  4CI3 B;  2YKG A;  1YZ1 A;  3ZD6 A;  3HCI A;  3HCJ A;  2FU5 A;  4TZU A;  2RQB A;  3E0O A;  2QFB A;  3EBM A;  3HCH A;  3MAO A;  4V2Y A;  4TZC A;  3FAC A;  4A2V A;  2LOY A;  2K8D A;  1L1D A;  1TXJ A;  5E3H A;  3LRN A;  5F9H A;  2RQA A;  4AY2 A;  1H7Y A;  3LRR A;  2KWB A;  3P3K A;  3DJM A;  3WX2 A;  5AMH A;  3EQT A;  2HR9 A;  3OG8 A; 
#chains in the Genus database with same CATH homology
 3GA3 A;  4BPB A;  5F9F A;  2LVL A;  2RMJ A;  3ZD7 A;  5F98 A;  2W4R A;  1FWQ A;  1H6Q A;  4A2X A;  1HXR A;  3NCU A;  2QFD A;  2YKG A;  1YZ1 A;  3ZD6 A;  2FU5 A;  2RQB A;  2QFB A;  3EBM A;  3FAC A;  4A2V A;  2LOY A;  1TXJ A;  5F9H A;  5E3H A;  3LRN A;  4AY2 A;  2RQA A;  1H7Y A;  3LRR A;  2KWB A;  3P3K A;  3DJM A;  3EQT A;  2HR9 A;  3OG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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