2QFBA

Crystal structure of the regulatory domain of human rig-i with bound zn
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 23
structure length 121
sequence length 121
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2007-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2qfbA00
2YKGA 3ZD7A 4AY2A 2QFBA 3LRNA 4A2XA 2RQBA 2RMJA 2RQAA 4A2VA 3GA3A 4BPBA 2QFDA 3OG8A 3EQTA 3ZD6A 5E3HA 2W4RA 5F98A 5F9FA 5F9HA 3NCUA 3LRRA
chains in the Genus database with same CATH superfamily
2KZNA 4V30A 4CI1B 3WX2A 3CXKA 2YKGA 2LVLA 3ZD7A 4AY2A 1FWQA 3E0OA 2QFBA 3MAOA 3LRNA 1H7YA 2FU5A 1H6QA 4A2XA 3CEZA 2RQBA 3DJMA 4TZCA 4V31A 2KV1A 3FACA 2KWBA 2HR9A 5AMHA 2RMJA 4V2YA 2RQAA 1HXRA 3HCGA 3EBMA 3HCHA 4CI2B 4A2VA 3GA3A 4BPBA 4TZUA 2QFDA 3OG8A 3EQTA 1YZ1A 3ZD6A 3HCIA 2K8DA 3P3KA 5E3HA 3WX1A 2W4RA 5F98A 2LOYA 3HCJA 1TXJA 4V2ZA 3E0MA 5F9FA 1L1DA 4CI3B 5F9HA 3NCUA 3LRRA 4TZ4C
chains in the Genus database with same CATH topology
2YKGA 3ZD7A 4AY2A 2LVLA 1FWQA 2QFBA 3LRNA 1H7YA 2FU5A 1H6QA 4A2XA 2RQBA 3DJMA 3FACA 2KWBA 2HR9A 2RMJA 2RQAA 1HXRA 3EBMA 4A2VA 3GA3A 4BPBA 2QFDA 3OG8A 3EQTA 1YZ1A 3ZD6A 3P3KA 5E3HA 2W4RA 5F98A 2LOYA 1TXJA 5F9FA 5F9HA 3NCUA 3LRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YKG A;  3ZD7 A;  4AY2 A;  2QFB A;  3LRN A;  4A2X A;  2RQB A;  2RMJ A;  2RQA A;  4A2V A;  3GA3 A;  4BPB A;  2QFD A;  3OG8 A;  3EQT A;  3ZD6 A;  5E3H A;  2W4R A;  5F98 A;  5F9F A;  5F9H A;  3NCU A;  3LRR A; 
#chains in the Genus database with same CATH topology
 2KZN A;  4V30 A;  4CI1 B;  3WX2 A;  3CXK A;  2YKG A;  2LVL A;  3ZD7 A;  4AY2 A;  1FWQ A;  3E0O A;  2QFB A;  3MAO A;  3LRN A;  1H7Y A;  2FU5 A;  1H6Q A;  4A2X A;  3CEZ A;  2RQB A;  3DJM A;  4TZC A;  4V31 A;  2KV1 A;  3FAC A;  2KWB A;  2HR9 A;  5AMH A;  2RMJ A;  4V2Y A;  2RQA A;  1HXR A;  3HCG A;  3EBM A;  3HCH A;  4CI2 B;  4A2V A;  3GA3 A;  4BPB A;  4TZU A;  2QFD A;  3OG8 A;  3EQT A;  1YZ1 A;  3ZD6 A;  3HCI A;  2K8D A;  3P3K A;  5E3H A;  3WX1 A;  2W4R A;  5F98 A;  2LOY A;  3HCJ A;  1TXJ A;  4V2Z A;  3E0M A;  5F9F A;  1L1D A;  4CI3 B;  5F9H A;  3NCU A;  3LRR A;  4TZ4 C; 
#chains in the Genus database with same CATH homology
 2YKG A;  3ZD7 A;  4AY2 A;  2LVL A;  1FWQ A;  2QFB A;  3LRN A;  1H7Y A;  2FU5 A;  1H6Q A;  4A2X A;  2RQB A;  3DJM A;  3FAC A;  2KWB A;  2HR9 A;  2RMJ A;  2RQA A;  1HXR A;  3EBM A;  4A2V A;  3GA3 A;  4BPB A;  2QFD A;  3OG8 A;  3EQT A;  1YZ1 A;  3ZD6 A;  3P3K A;  5E3H A;  2W4R A;  5F98 A;  2LOY A;  1TXJ A;  5F9F A;  5F9H A;  3NCU A;  3LRR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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