2QFDA

Crystal structure of the regulatory domain of human rig-i with bound hg
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 23
structure length 121
sequence length 121
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2007-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2qfdA00
2W4RA 4A2VA 5F9FA 3ZD6A 2RMJA 3LRRA 3EQTA 2QFDA 2RQAA 2QFBA 2RQBA 3NCUA 2YKGA 5F9HA 4A2XA 3OG8A 5E3HA 3LRNA 4BPBA 4AY2A 5F98A 3GA3A 3ZD7A
chains in the Genus database with same CATH superfamily
1H6QA 2W4RA 4TZUA 4A2VA 4CI2B 5F9FA 3DJMA 1H7YA 2LOYA 1L1DA 3HCIA 4TZCA 3ZD6A 2HR9A 2RMJA 3HCHA 4CI1B 3HCJA 1YZ1A 2KWBA 3LRRA 3FACA 3CXKA 3EQTA 2QFDA 3CEZA 2RQAA 3P3KA 2QFBA 3E0MA 2RQBA 4V31A 3NCUA 2YKGA 4V30A 3E0OA 4TZ4C 1HXRA 1TXJA 5F9HA 4A2XA 3WX1A 2LVLA 4CI3B 1FWQA 3MAOA 4V2ZA 2KZNA 3WX2A 3OG8A 5E3HA 4V2YA 3LRNA 2FU5A 4BPBA 4AY2A 3HCGA 3EBMA 3GA3A 5F98A 3ZD7A 2KV1A 2K8DA 5AMHA
chains in the Genus database with same CATH topology
1H6QA 2W4RA 4A2VA 5F9FA 1H7YA 3DJMA 2LOYA 3ZD6A 2HR9A 2RMJA 1YZ1A 2KWBA 3LRRA 3FACA 3EQTA 2QFDA 3P3KA 2RQAA 2QFBA 2RQBA 3NCUA 2YKGA 1HXRA 1TXJA 5F9HA 4A2XA 2LVLA 1FWQA 3OG8A 5E3HA 3LRNA 4BPBA 2FU5A 4AY2A 3EBMA 3GA3A 5F98A 3ZD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W4R A;  4A2V A;  5F9F A;  3ZD6 A;  2RMJ A;  3LRR A;  3EQT A;  2QFD A;  2RQA A;  2QFB A;  2RQB A;  3NCU A;  2YKG A;  5F9H A;  4A2X A;  3OG8 A;  5E3H A;  3LRN A;  4BPB A;  4AY2 A;  5F98 A;  3GA3 A;  3ZD7 A; 
#chains in the Genus database with same CATH topology
 1H6Q A;  2W4R A;  4TZU A;  4A2V A;  4CI2 B;  5F9F A;  3DJM A;  1H7Y A;  2LOY A;  1L1D A;  3HCI A;  4TZC A;  3ZD6 A;  2HR9 A;  2RMJ A;  3HCH A;  4CI1 B;  3HCJ A;  1YZ1 A;  2KWB A;  3LRR A;  3FAC A;  3CXK A;  3EQT A;  2QFD A;  3CEZ A;  2RQA A;  3P3K A;  2QFB A;  3E0M A;  2RQB A;  4V31 A;  3NCU A;  2YKG A;  4V30 A;  3E0O A;  4TZ4 C;  1HXR A;  1TXJ A;  5F9H A;  4A2X A;  3WX1 A;  2LVL A;  4CI3 B;  1FWQ A;  3MAO A;  4V2Z A;  2KZN A;  3WX2 A;  3OG8 A;  5E3H A;  4V2Y A;  3LRN A;  2FU5 A;  4BPB A;  4AY2 A;  3HCG A;  3EBM A;  3GA3 A;  5F98 A;  3ZD7 A;  2KV1 A;  2K8D A;  5AMH A; 
#chains in the Genus database with same CATH homology
 1H6Q A;  2W4R A;  4A2V A;  5F9F A;  1H7Y A;  3DJM A;  2LOY A;  3ZD6 A;  2HR9 A;  2RMJ A;  1YZ1 A;  2KWB A;  3LRR A;  3FAC A;  3EQT A;  2QFD A;  3P3K A;  2RQA A;  2QFB A;  2RQB A;  3NCU A;  2YKG A;  1HXR A;  1TXJ A;  5F9H A;  4A2X A;  2LVL A;  1FWQ A;  3OG8 A;  5E3H A;  3LRN A;  4BPB A;  2FU5 A;  4AY2 A;  3EBM A;  3GA3 A;  5F98 A;  3ZD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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