2RMJA

Solution structure of rig-i c-terminal domain
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
134
structure length
134
Chain Sequence
DSQEKPKPVPDKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEMSK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 9
structure length 134
sequence length 134
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2007-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rmjA00
4AY2A 5E3HA 4BPBA 2QFDA 5F98A 2QFBA 3OG8A 5F9HA 2RMJA 3LRRA 3LRNA 5F9FA 2YKGA 3GA3A 3EQTA 2RQAA 4A2XA 2W4RA 2RQBA 3ZD6A 3ZD7A 3NCUA 4A2VA
chains in the Genus database with same CATH superfamily
2KV1A 3HCJA 4TZCA 4TZUA 2HR9A 2K8DA 1FWQA 3HCIA 4TZ4C 4CI3B 3NCUA 4AY2A 4V30A 1H7YA 4CI1B 3E0MA 3HCGA 5E3HA 4BPBA 2QFDA 2KWBA 3FACA 3DJMA 2LVLA 1TXJA 2QFBA 5F98A 3E0OA 3OG8A 4V2YA 5F9HA 3LRNA 3LRRA 5F9FA 4CI2B 2YKGA 3HCHA 3CXKA 4V2ZA 3GA3A 1L1DA 1H6QA 3EQTA 3EBMA 5AMHA 2FU5A 2LOYA 2RQAA 1YZ1A 3CEZA 4V31A 3P3KA 4A2VA 4A2XA 2W4RA 3WX2A 2RQBA 3ZD6A 1HXRA 2KZNA 3MAOA 3ZD7A 3WX1A 2RMJA
chains in the Genus database with same CATH topology
2HR9A 1FWQA 4AY2A 1H7YA 5E3HA 4BPBA 2QFDA 2KWBA 3FACA 3DJMA 2LVLA 1TXJA 2QFBA 5F98A 3OG8A 5F9HA 3LRNA 3LRRA 5F9FA 2YKGA 3GA3A 1H6QA 3EQTA 3EBMA 2FU5A 2LOYA 2RQAA 1YZ1A 4A2XA 3P3KA 4A2VA 2W4RA 2RQBA 3ZD6A 1HXRA 3ZD7A 3NCUA 2RMJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AY2 A;  5E3H A;  4BPB A;  2QFD A;  5F98 A;  2QFB A;  3OG8 A;  5F9H A;  2RMJ A;  3LRR A;  3LRN A;  5F9F A;  2YKG A;  3GA3 A;  3EQT A;  2RQA A;  4A2X A;  2W4R A;  2RQB A;  3ZD6 A;  3ZD7 A;  3NCU A;  4A2V A; 
#chains in the Genus database with same CATH topology
 2KV1 A;  3HCJ A;  4TZC A;  4TZU A;  2HR9 A;  2K8D A;  1FWQ A;  3HCI A;  4TZ4 C;  4CI3 B;  3NCU A;  4AY2 A;  4V30 A;  1H7Y A;  4CI1 B;  3E0M A;  3HCG A;  5E3H A;  4BPB A;  2QFD A;  2KWB A;  3FAC A;  3DJM A;  2LVL A;  1TXJ A;  2QFB A;  5F98 A;  3E0O A;  3OG8 A;  4V2Y A;  5F9H A;  3LRN A;  3LRR A;  5F9F A;  4CI2 B;  2YKG A;  3HCH A;  3CXK A;  4V2Z A;  3GA3 A;  1L1D A;  1H6Q A;  3EQT A;  3EBM A;  5AMH A;  2FU5 A;  2LOY A;  2RQA A;  1YZ1 A;  3CEZ A;  4V31 A;  3P3K A;  4A2V A;  4A2X A;  2W4R A;  3WX2 A;  2RQB A;  3ZD6 A;  1HXR A;  2KZN A;  3MAO A;  3ZD7 A;  3WX1 A;  2RMJ A; 
#chains in the Genus database with same CATH homology
 2HR9 A;  1FWQ A;  4AY2 A;  1H7Y A;  5E3H A;  4BPB A;  2QFD A;  2KWB A;  3FAC A;  3DJM A;  2LVL A;  1TXJ A;  2QFB A;  5F98 A;  3OG8 A;  5F9H A;  3LRN A;  3LRR A;  5F9F A;  2YKG A;  3GA3 A;  1H6Q A;  3EQT A;  3EBM A;  2FU5 A;  2LOY A;  2RQA A;  1YZ1 A;  4A2X A;  3P3K A;  4A2V A;  2W4R A;  2RQB A;  3ZD6 A;  1HXR A;  3ZD7 A;  3NCU A;  2RMJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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