2RQBA

Solution structure of mda5 ctd
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
135
structure length
135
Chain Sequence
GPLGSYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structures of Cytosolic RNA Sensor MDA5 and LGP2 C-terminal Domains: IDENTIFICATION OF THE RNA RECOGNITION LOOP IN RIG-I-LIKE RECEPTORS
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Interferon-induced helicase C domain-containing protein 1
total genus 12
structure length 135
sequence length 135
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2rqbA00
5F9HA 3LRNA 3ZD6A 2YKGA 4A2XA 2RMJA 5F9FA 3EQTA 2QFBA 3ZD7A 4AY2A 4BPBA 3NCUA 2RQBA 2RQAA 5E3HA 2QFDA 5F98A 3GA3A 3OG8A 2W4RA 3LRRA 4A2VA
chains in the Genus database with same CATH superfamily
2K8DA 3E0OA 3HCIA 3WX2A 4CI3B 4CI1B 5F9HA 1L1DA 3LRNA 4V2YA 2KZNA 3CEZA 1YZ1A 4TZCA 4V30A 3HCGA 4V31A 2LOYA 3ZD6A 3FACA 2FU5A 3WX1A 4CI2B 4TZ4C 3E0MA 3HCJA 3CXKA 3EBMA 1H7YA 2YKGA 4A2XA 2RMJA 3MAOA 5AMHA 5F9FA 1H6QA 3EQTA 3DJMA 3P3KA 2KWBA 2QFBA 3ZD7A 4AY2A 4BPBA 3NCUA 2RQBA 1HXRA 2KV1A 2RQAA 1TXJA 2LVLA 5E3HA 1FWQA 2QFDA 5F98A 3GA3A 4V2ZA 3OG8A 3HCHA 2W4RA 3LRRA 2HR9A 4TZUA 4A2VA
chains in the Genus database with same CATH topology
5F9HA 3LRNA 1YZ1A 2LOYA 3ZD6A 3FACA 2FU5A 3EBMA 1H7YA 2YKGA 4A2XA 2RMJA 5F9FA 1H6QA 3EQTA 3DJMA 3P3KA 2KWBA 2QFBA 3ZD7A 4AY2A 4BPBA 3NCUA 2RQBA 1HXRA 2RQAA 1TXJA 2LVLA 5E3HA 1FWQA 2QFDA 5F98A 3GA3A 3OG8A 2W4RA 3LRRA 2HR9A 4A2VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F9H A;  3LRN A;  3ZD6 A;  2YKG A;  4A2X A;  2RMJ A;  5F9F A;  3EQT A;  2QFB A;  3ZD7 A;  4AY2 A;  4BPB A;  3NCU A;  2RQB A;  2RQA A;  5E3H A;  2QFD A;  5F98 A;  3GA3 A;  3OG8 A;  2W4R A;  3LRR A;  4A2V A; 
#chains in the Genus database with same CATH topology
 2K8D A;  3E0O A;  3HCI A;  3WX2 A;  4CI3 B;  4CI1 B;  5F9H A;  1L1D A;  3LRN A;  4V2Y A;  2KZN A;  3CEZ A;  1YZ1 A;  4TZC A;  4V30 A;  3HCG A;  4V31 A;  2LOY A;  3ZD6 A;  3FAC A;  2FU5 A;  3WX1 A;  4CI2 B;  4TZ4 C;  3E0M A;  3HCJ A;  3CXK A;  3EBM A;  1H7Y A;  2YKG A;  4A2X A;  2RMJ A;  3MAO A;  5AMH A;  5F9F A;  1H6Q A;  3EQT A;  3DJM A;  3P3K A;  2KWB A;  2QFB A;  3ZD7 A;  4AY2 A;  4BPB A;  3NCU A;  2RQB A;  1HXR A;  2KV1 A;  2RQA A;  1TXJ A;  2LVL A;  5E3H A;  1FWQ A;  2QFD A;  5F98 A;  3GA3 A;  4V2Z A;  3OG8 A;  3HCH A;  2W4R A;  3LRR A;  2HR9 A;  4TZU A;  4A2V A; 
#chains in the Genus database with same CATH homology
 5F9H A;  3LRN A;  1YZ1 A;  2LOY A;  3ZD6 A;  3FAC A;  2FU5 A;  3EBM A;  1H7Y A;  2YKG A;  4A2X A;  2RMJ A;  5F9F A;  1H6Q A;  3EQT A;  3DJM A;  3P3K A;  2KWB A;  2QFB A;  3ZD7 A;  4AY2 A;  4BPB A;  3NCU A;  2RQB A;  1HXR A;  2RQA A;  1TXJ A;  2LVL A;  5E3H A;  1FWQ A;  2QFD A;  5F98 A;  3GA3 A;  3OG8 A;  2W4R A;  3LRR A;  2HR9 A;  4A2V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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