2W4RA

Crystal structure of the regulatory domain of human lgp2
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
131
structure length
125
Chain Sequence
RQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDVFKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVPDFDFLQHCAENLSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROBABLE ATP-DEPENDENT RNA HELICASE DHX58
total genus 21
structure length 125
sequence length 131
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2w4rA00
4A2VA 5F98A 2YKGA 5F9HA 2RQBA 4A2XA 3ZD7A 5E3HA 5F9FA 3GA3A 3NCUA 3LRNA 2QFBA 2QFDA 2RQAA 2W4RA 4BPBA 3LRRA 2RMJA 4AY2A 3EQTA 3OG8A 3ZD6A
chains in the Genus database with same CATH superfamily
4A2VA 2HR9A 2LVLA 2KV1A 2KZNA 5F98A 4TZCA 3WX1A 2YKGA 3CEZA 4TZUA 5F9HA 3HCHA 3P3KA 4V2ZA 2RQBA 3WX2A 4A2XA 3EBMA 3ZD7A 1H7YA 3FACA 4TZ4C 5E3HA 3CXKA 4V30A 4V31A 5F9FA 3DJMA 3GA3A 4CI1B 3HCJA 3MAOA 5AMHA 3NCUA 2QFBA 3LRNA 2QFDA 2LOYA 1YZ1A 1H6QA 2RQAA 4V2YA 2W4RA 4BPBA 4CI2B 3E0OA 3LRRA 1TXJA 1HXRA 2RMJA 1L1DA 2K8DA 4CI3B 1FWQA 3E0MA 4AY2A 3HCGA 3EQTA 3HCIA 3OG8A 2KWBA 2FU5A 3ZD6A
chains in the Genus database with same CATH topology
4A2VA 2HR9A 2LVLA 5F98A 2YKGA 5F9HA 3P3KA 2RQBA 4A2XA 3EBMA 3ZD7A 1H7YA 3FACA 5E3HA 5F9FA 3DJMA 3GA3A 3NCUA 2QFBA 3LRNA 2QFDA 2LOYA 1YZ1A 1H6QA 2RQAA 2W4RA 4BPBA 3LRRA 1TXJA 1HXRA 2RMJA 1FWQA 4AY2A 3EQTA 3OG8A 2KWBA 2FU5A 3ZD6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A2V A;  5F98 A;  2YKG A;  5F9H A;  2RQB A;  4A2X A;  3ZD7 A;  5E3H A;  5F9F A;  3GA3 A;  3NCU A;  3LRN A;  2QFB A;  2QFD A;  2RQA A;  2W4R A;  4BPB A;  3LRR A;  2RMJ A;  4AY2 A;  3EQT A;  3OG8 A;  3ZD6 A; 
#chains in the Genus database with same CATH topology
 4A2V A;  2HR9 A;  2LVL A;  2KV1 A;  2KZN A;  5F98 A;  4TZC A;  3WX1 A;  2YKG A;  3CEZ A;  4TZU A;  5F9H A;  3HCH A;  3P3K A;  4V2Z A;  2RQB A;  3WX2 A;  4A2X A;  3EBM A;  3ZD7 A;  1H7Y A;  3FAC A;  4TZ4 C;  5E3H A;  3CXK A;  4V30 A;  4V31 A;  5F9F A;  3DJM A;  3GA3 A;  4CI1 B;  3HCJ A;  3MAO A;  5AMH A;  3NCU A;  2QFB A;  3LRN A;  2QFD A;  2LOY A;  1YZ1 A;  1H6Q A;  2RQA A;  4V2Y A;  2W4R A;  4BPB A;  4CI2 B;  3E0O A;  3LRR A;  1TXJ A;  1HXR A;  2RMJ A;  1L1D A;  2K8D A;  4CI3 B;  1FWQ A;  3E0M A;  4AY2 A;  3HCG A;  3EQT A;  3HCI A;  3OG8 A;  2KWB A;  2FU5 A;  3ZD6 A; 
#chains in the Genus database with same CATH homology
 4A2V A;  2HR9 A;  2LVL A;  5F98 A;  2YKG A;  5F9H A;  3P3K A;  2RQB A;  4A2X A;  3EBM A;  3ZD7 A;  1H7Y A;  3FAC A;  5E3H A;  5F9F A;  3DJM A;  3GA3 A;  3NCU A;  2QFB A;  3LRN A;  2QFD A;  2LOY A;  1YZ1 A;  1H6Q A;  2RQA A;  2W4R A;  4BPB A;  3LRR A;  1TXJ A;  1HXR A;  2RMJ A;  1FWQ A;  4AY2 A;  3EQT A;  3OG8 A;  2KWB A;  2FU5 A;  3ZD6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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