3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
2JNUA 2AF0A 2IK8B 3C7KB 3CIKA 2ODEB 4MK0A 1OMWA 3NYNA 1EZYA 2OWIA 1CMZA 2JM5A 2IHDA 5HE3A 3NYOA 1FQKB 3KRWA 2GTPC 3PVWA 4PNKA 2CRPA 2BCJA 5HE2A 3V5WA 5DO9B 3UZTA 2EBZA 2D9JA 2V4ZB 2BV1A 3C7LA 1FQJB 5HE1A 2BT2A 4TNBA 1AGRE 5HE0A 2DLVA 2OJ4A 1EMUA 3KRXA 1DK8A 2IHBB 4TNDA 4EKDB 1FQIA 3PSCA 3PVUA 1EZTA
chains in the Genus database with same CATH superfamily
2JNUA 2AF0A 2IK8B 3C7KB 3CIKA 2ODEB 4MK0A 1OMWA 3NYNA 1EZYA 2OWIA 1CMZA 2JM5A 2IHDA 5HE3A 3NYOA 1FQKB 3KRWA 2GTPC 3PVWA 4PNKA 2CRPA 3I5QA 2BCJA 5HE2A 3V5WA 5DO9B 3UZTA 2EBZA 2D9JA 2V4ZB 4HTEA 5REQB 2BV1A 3C7LA 1FQJB 5HE1A 2BT2A 4TNBA 1AGRE 5HE0A 2DLVA 2OJ4A 1EMUA 3KRXA 1DK8A 2IHBB 4TNDA 4EKDB 1FQIA 3PSCA 3PVUA 3QYFA 1EZTA
chains in the Genus database with same CATH topology
2JNUA 2AF0A 2IK8B 3C7KB 3CIKA 2ODEB 4MK0A 1OMWA 3NYNA 1EZYA 2OWIA 1CMZA 2JM5A 2IHDA 5HE3A 3NYOA 1FQKB 3KRWA 2GTPC 3PVWA 4PNKA 2CRPA 2BCJA 5HE2A 3V5WA 5DO9B 3UZTA 2EBZA 2D9JA 2V4ZB 5REQB 2BV1A 3C7LA 1FQJB 5HE1A 2BT2A 4TNBA 1AGRE 5HE0A 2DLVA 2OJ4A 1EMUA 3KRXA 1DK8A 2IHBB 4TNDA 4EKDB 1FQIA 3PSCA 3PVUA 3QYFA 1EZTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JNU A;  2AF0 A;  2IK8 B;  3C7K B;  3CIK A;  2ODE B;  4MK0 A;  1OMW A;  3NYN A;  1EZY A;  2OWI A;  1CMZ A;  2JM5 A;  2IHD A;  5HE3 A;  3NYO A;  1FQK B;  3KRW A;  2GTP C;  3PVW A;  4PNK A;  2CRP A;  2BCJ A;  5HE2 A;  3V5W A;  5DO9 B;  3UZT A;  2EBZ A;  2D9J A;  2V4Z B;  2BV1 A;  3C7L A;  1FQJ B;  5HE1 A;  2BT2 A;  4TNB A;  1AGR E;  5HE0 A;  2DLV A;  2OJ4 A;  1EMU A;  3KRX A;  1DK8 A;  2IHB B;  4TND A;  4EKD B;  1FQI A;  3PSC A;  3PVU A;  1EZT A; 
#chains in the Genus database with same CATH topology
 2JNU A;  2AF0 A;  2IK8 B;  3C7K B;  3CIK A;  2ODE B;  4MK0 A;  1OMW A;  3NYN A;  1EZY A;  2OWI A;  1CMZ A;  2JM5 A;  2IHD A;  5HE3 A;  3NYO A;  1FQK B;  3KRW A;  2GTP C;  3PVW A;  4PNK A;  2CRP A;  3I5Q A;  2BCJ A;  5HE2 A;  3V5W A;  5DO9 B;  3UZT A;  2EBZ A;  2D9J A;  2V4Z B;  4HTE A;  5REQ B;  2BV1 A;  3C7L A;  1FQJ B;  5HE1 A;  2BT2 A;  4TNB A;  1AGR E;  5HE0 A;  2DLV A;  2OJ4 A;  1EMU A;  3KRX A;  1DK8 A;  2IHB B;  4TND A;  4EKD B;  1FQI A;  3PSC A;  3PVU A;  3QYF A;  1EZT A; 
#chains in the Genus database with same CATH homology
 2JNU A;  2AF0 A;  2IK8 B;  3C7K B;  3CIK A;  2ODE B;  4MK0 A;  1OMW A;  3NYN A;  1EZY A;  2OWI A;  1CMZ A;  2JM5 A;  2IHD A;  5HE3 A;  3NYO A;  1FQK B;  3KRW A;  2GTP C;  3PVW A;  4PNK A;  2CRP A;  2BCJ A;  5HE2 A;  3V5W A;  5DO9 B;  3UZT A;  2EBZ A;  2D9J A;  2V4Z B;  5REQ B;  2BV1 A;  3C7L A;  1FQJ B;  5HE1 A;  2BT2 A;  4TNB A;  1AGR E;  5HE0 A;  2DLV A;  2OJ4 A;  1EMU A;  3KRX A;  1DK8 A;  2IHB B;  4TND A;  4EKD B;  1FQI A;  3PSC A;  3PVU A;  3QYF A;  1EZT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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