3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
molecule tags Signaling protein
source organism Mus musculus
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
5DO9B 2CRPA 3NYNA 3PVUA 5HE0A 3UZTA 1EMUA 2BT2A 3KRXA 4MK0A 2D9JA 2AF0A 3NYOA 2JM5A 1FQJB 1FQKB 2OJ4A 3C7LA 2GTPC 1AGRE 2JNUA 2EBZA 1FQIA 3PVWA 5HE3A 2DLVA 2BCJA 2BV1A 4PNKA 3V5WA 1EZYA 3PSCA 2IHDA 1CMZA 5HE2A 5HE1A 2OWIA 3C7KB 3CIKA 2ODEB 4EKDB 3KRWA 4TNBA 1DK8A 2IHBB 1OMWA 2IK8B 4TNDA 1EZTA 2V4ZB
chains in the Genus database with same CATH superfamily
3I5QA 5DO9B 2CRPA 3NYNA 3PVUA 5HE0A 3UZTA 1EMUA 2BT2A 3KRXA 4MK0A 4HTEA 2D9JA 2AF0A 3NYOA 2JM5A 1FQJB 1FQKB 2OJ4A 3C7LA 2GTPC 1AGRE 2JNUA 2EBZA 1FQIA 3PVWA 5HE3A 2DLVA 2BCJA 2BV1A 4PNKA 3V5WA 1EZYA 5REQB 3PSCA 2IHDA 3QYFA 1CMZA 5HE2A 5HE1A 2OWIA 3C7KB 3CIKA 2ODEB 4EKDB 3KRWA 4TNBA 1DK8A 2IHBB 1OMWA 2IK8B 4TNDA 1EZTA 2V4ZB
chains in the Genus database with same CATH topology
5DO9B 2CRPA 3NYNA 3PVUA 5HE0A 3UZTA 1EMUA 2BT2A 3KRXA 4MK0A 2D9JA 2AF0A 3NYOA 2JM5A 1FQJB 1FQKB 2OJ4A 3C7LA 2GTPC 1AGRE 2JNUA 2EBZA 1FQIA 3PVWA 5HE3A 2DLVA 2BCJA 2BV1A 4PNKA 3V5WA 1EZYA 5REQB 3PSCA 2IHDA 3QYFA 1CMZA 5HE2A 5HE1A 2OWIA 3C7KB 3CIKA 2ODEB 4EKDB 3KRWA 4TNBA 1DK8A 2IHBB 1OMWA 2IK8B 4TNDA 1EZTA 2V4ZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DO9 B;  2CRP A;  3NYN A;  3PVU A;  5HE0 A;  3UZT A;  1EMU A;  2BT2 A;  3KRX A;  4MK0 A;  2D9J A;  2AF0 A;  3NYO A;  2JM5 A;  1FQJ B;  1FQK B;  2OJ4 A;  3C7L A;  2GTP C;  1AGR E;  2JNU A;  2EBZ A;  1FQI A;  3PVW A;  5HE3 A;  2DLV A;  2BCJ A;  2BV1 A;  4PNK A;  3V5W A;  1EZY A;  3PSC A;  2IHD A;  1CMZ A;  5HE2 A;  5HE1 A;  2OWI A;  3C7K B;  3CIK A;  2ODE B;  4EKD B;  3KRW A;  4TNB A;  1DK8 A;  2IHB B;  1OMW A;  2IK8 B;  4TND A;  1EZT A;  2V4Z B; 
#chains in the Genus database with same CATH topology
 3I5Q A;  5DO9 B;  2CRP A;  3NYN A;  3PVU A;  5HE0 A;  3UZT A;  1EMU A;  2BT2 A;  3KRX A;  4MK0 A;  4HTE A;  2D9J A;  2AF0 A;  3NYO A;  2JM5 A;  1FQJ B;  1FQK B;  2OJ4 A;  3C7L A;  2GTP C;  1AGR E;  2JNU A;  2EBZ A;  1FQI A;  3PVW A;  5HE3 A;  2DLV A;  2BCJ A;  2BV1 A;  4PNK A;  3V5W A;  1EZY A;  5REQ B;  3PSC A;  2IHD A;  3QYF A;  1CMZ A;  5HE2 A;  5HE1 A;  2OWI A;  3C7K B;  3CIK A;  2ODE B;  4EKD B;  3KRW A;  4TNB A;  1DK8 A;  2IHB B;  1OMW A;  2IK8 B;  4TND A;  1EZT A;  2V4Z B; 
#chains in the Genus database with same CATH homology
 5DO9 B;  2CRP A;  3NYN A;  3PVU A;  5HE0 A;  3UZT A;  1EMU A;  2BT2 A;  3KRX A;  4MK0 A;  2D9J A;  2AF0 A;  3NYO A;  2JM5 A;  1FQJ B;  1FQK B;  2OJ4 A;  3C7L A;  2GTP C;  1AGR E;  2JNU A;  2EBZ A;  1FQI A;  3PVW A;  5HE3 A;  2DLV A;  2BCJ A;  2BV1 A;  4PNK A;  3V5W A;  1EZY A;  5REQ B;  3PSC A;  2IHD A;  3QYF A;  1CMZ A;  5HE2 A;  5HE1 A;  2OWI A;  3C7K B;  3CIK A;  2ODE B;  4EKD B;  3KRW A;  4TNB A;  1DK8 A;  2IHB B;  1OMW A;  2IK8 B;  4TND A;  1EZT A;  2V4Z B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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