3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
molecule tags Signaling protein
source organism Mus musculus
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
5HE2A 1FQJB 2D9JA 2IHDA 2V4ZB 1OMWA 1FQKB 3NYNA 3C7LA 2JM5A 5HE0A 4EKDB 2ODEB 2EBZA 2OJ4A 4PNKA 3UZTA 5HE3A 1CMZA 4TNBA 1DK8A 1EZYA 1EMUA 3KRXA 2CRPA 2BV1A 3CIKA 2OWIA 2BT2A 3KRWA 3PVUA 1FQIA 4TNDA 2AF0A 2IK8B 3V5WA 2IHBB 3NYOA 3PSCA 3PVWA 5HE1A 5DO9B 2DLVA 2GTPC 1AGRE 2BCJA 2JNUA 1EZTA 4MK0A 3C7KB
chains in the Genus database with same CATH superfamily
5HE2A 1FQJB 2D9JA 2IHDA 2V4ZB 1OMWA 1FQKB 3NYNA 3C7LA 2JM5A 5HE0A 4EKDB 2ODEB 2EBZA 2OJ4A 4PNKA 3UZTA 5HE3A 1CMZA 4TNBA 1DK8A 1EZYA 1EMUA 5REQB 3KRXA 2CRPA 2BV1A 4HTEA 3CIKA 2OWIA 2BT2A 3KRWA 3PVUA 1FQIA 4TNDA 2AF0A 2IK8B 3I5QA 3V5WA 2IHBB 3NYOA 3PSCA 3PVWA 5HE1A 5DO9B 2DLVA 2GTPC 1AGRE 2BCJA 2JNUA 1EZTA 4MK0A 3C7KB 3QYFA
chains in the Genus database with same CATH topology
5HE2A 1FQJB 2D9JA 2IHDA 2V4ZB 1OMWA 1FQKB 3NYNA 3C7LA 2JM5A 5HE0A 4EKDB 2ODEB 2EBZA 2OJ4A 4PNKA 3UZTA 5HE3A 1CMZA 4TNBA 1DK8A 1EZYA 1EMUA 5REQB 3KRXA 2CRPA 2BV1A 3CIKA 2OWIA 2BT2A 3KRWA 3PVUA 1FQIA 4TNDA 2AF0A 2IK8B 3V5WA 2IHBB 3NYOA 3PSCA 3PVWA 5HE1A 5DO9B 2DLVA 2GTPC 1AGRE 2BCJA 2JNUA 1EZTA 4MK0A 3C7KB 3QYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HE2 A;  1FQJ B;  2D9J A;  2IHD A;  2V4Z B;  1OMW A;  1FQK B;  3NYN A;  3C7L A;  2JM5 A;  5HE0 A;  4EKD B;  2ODE B;  2EBZ A;  2OJ4 A;  4PNK A;  3UZT A;  5HE3 A;  1CMZ A;  4TNB A;  1DK8 A;  1EZY A;  1EMU A;  3KRX A;  2CRP A;  2BV1 A;  3CIK A;  2OWI A;  2BT2 A;  3KRW A;  3PVU A;  1FQI A;  4TND A;  2AF0 A;  2IK8 B;  3V5W A;  2IHB B;  3NYO A;  3PSC A;  3PVW A;  5HE1 A;  5DO9 B;  2DLV A;  2GTP C;  1AGR E;  2BCJ A;  2JNU A;  1EZT A;  4MK0 A;  3C7K B; 
#chains in the Genus database with same CATH topology
 5HE2 A;  1FQJ B;  2D9J A;  2IHD A;  2V4Z B;  1OMW A;  1FQK B;  3NYN A;  3C7L A;  2JM5 A;  5HE0 A;  4EKD B;  2ODE B;  2EBZ A;  2OJ4 A;  4PNK A;  3UZT A;  5HE3 A;  1CMZ A;  4TNB A;  1DK8 A;  1EZY A;  1EMU A;  5REQ B;  3KRX A;  2CRP A;  2BV1 A;  4HTE A;  3CIK A;  2OWI A;  2BT2 A;  3KRW A;  3PVU A;  1FQI A;  4TND A;  2AF0 A;  2IK8 B;  3I5Q A;  3V5W A;  2IHB B;  3NYO A;  3PSC A;  3PVW A;  5HE1 A;  5DO9 B;  2DLV A;  2GTP C;  1AGR E;  2BCJ A;  2JNU A;  1EZT A;  4MK0 A;  3C7K B;  3QYF A; 
#chains in the Genus database with same CATH homology
 5HE2 A;  1FQJ B;  2D9J A;  2IHD A;  2V4Z B;  1OMW A;  1FQK B;  3NYN A;  3C7L A;  2JM5 A;  5HE0 A;  4EKD B;  2ODE B;  2EBZ A;  2OJ4 A;  4PNK A;  3UZT A;  5HE3 A;  1CMZ A;  4TNB A;  1DK8 A;  1EZY A;  1EMU A;  5REQ B;  3KRX A;  2CRP A;  2BV1 A;  3CIK A;  2OWI A;  2BT2 A;  3KRW A;  3PVU A;  1FQI A;  4TND A;  2AF0 A;  2IK8 B;  3V5W A;  2IHB B;  3NYO A;  3PSC A;  3PVW A;  5HE1 A;  5DO9 B;  2DLV A;  2GTP C;  1AGR E;  2BCJ A;  2JNU A;  1EZT A;  4MK0 A;  3C7K B;  3QYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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