3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
molecule tags Signaling protein
source organism Mus musculus
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
5DO9B 3NYOA 2IHBB 2CRPA 2BV1A 2GTPC 2OWIA 3PVWA 2BCJA 2JNUA 5HE1A 3C7KB 2ODEB 1FQKB 2AF0A 1EZYA 2BT2A 3PSCA 1OMWA 3PVUA 2IK8B 2OJ4A 2IHDA 3NYNA 5HE0A 3V5WA 2DLVA 3C7LA 4EKDB 2V4ZB 1AGRE 2JM5A 4TNDA 1FQIA 3UZTA 3KRXA 5HE2A 1FQJB 3KRWA 4PNKA 4TNBA 5HE3A 1DK8A 1CMZA 1EZTA 2EBZA 4MK0A 2D9JA 1EMUA 3CIKA
chains in the Genus database with same CATH superfamily
5DO9B 3QYFA 3NYOA 2IHBB 2CRPA 2BV1A 5REQB 2GTPC 2OWIA 3PVWA 2BCJA 2JNUA 5HE1A 3C7KB 2ODEB 1FQKB 4HTEA 2AF0A 1EZYA 2BT2A 3PSCA 1OMWA 3PVUA 2IK8B 2OJ4A 2IHDA 3NYNA 3I5QA 5HE0A 3V5WA 2DLVA 3C7LA 4EKDB 2V4ZB 1AGRE 2JM5A 4TNDA 1FQIA 3UZTA 3KRXA 5HE2A 1FQJB 3KRWA 4PNKA 4TNBA 5HE3A 1DK8A 1CMZA 1EZTA 2EBZA 4MK0A 2D9JA 1EMUA 3CIKA
chains in the Genus database with same CATH topology
5DO9B 3QYFA 3NYOA 2IHBB 2CRPA 2BV1A 5REQB 2GTPC 2OWIA 3PVWA 2BCJA 2JNUA 5HE1A 3C7KB 2ODEB 1FQKB 2AF0A 1EZYA 2BT2A 3PSCA 1OMWA 3PVUA 2IK8B 2OJ4A 2IHDA 3NYNA 5HE0A 3V5WA 2DLVA 3C7LA 4EKDB 2V4ZB 1AGRE 2JM5A 4TNDA 1FQIA 3UZTA 3KRXA 5HE2A 1FQJB 3KRWA 4PNKA 4TNBA 5HE3A 1DK8A 1CMZA 1EZTA 2EBZA 4MK0A 2D9JA 1EMUA 3CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DO9 B;  3NYO A;  2IHB B;  2CRP A;  2BV1 A;  2GTP C;  2OWI A;  3PVW A;  2BCJ A;  2JNU A;  5HE1 A;  3C7K B;  2ODE B;  1FQK B;  2AF0 A;  1EZY A;  2BT2 A;  3PSC A;  1OMW A;  3PVU A;  2IK8 B;  2OJ4 A;  2IHD A;  3NYN A;  5HE0 A;  3V5W A;  2DLV A;  3C7L A;  4EKD B;  2V4Z B;  1AGR E;  2JM5 A;  4TND A;  1FQI A;  3UZT A;  3KRX A;  5HE2 A;  1FQJ B;  3KRW A;  4PNK A;  4TNB A;  5HE3 A;  1DK8 A;  1CMZ A;  1EZT A;  2EBZ A;  4MK0 A;  2D9J A;  1EMU A;  3CIK A; 
#chains in the Genus database with same CATH topology
 5DO9 B;  3QYF A;  3NYO A;  2IHB B;  2CRP A;  2BV1 A;  5REQ B;  2GTP C;  2OWI A;  3PVW A;  2BCJ A;  2JNU A;  5HE1 A;  3C7K B;  2ODE B;  1FQK B;  4HTE A;  2AF0 A;  1EZY A;  2BT2 A;  3PSC A;  1OMW A;  3PVU A;  2IK8 B;  2OJ4 A;  2IHD A;  3NYN A;  3I5Q A;  5HE0 A;  3V5W A;  2DLV A;  3C7L A;  4EKD B;  2V4Z B;  1AGR E;  2JM5 A;  4TND A;  1FQI A;  3UZT A;  3KRX A;  5HE2 A;  1FQJ B;  3KRW A;  4PNK A;  4TNB A;  5HE3 A;  1DK8 A;  1CMZ A;  1EZT A;  2EBZ A;  4MK0 A;  2D9J A;  1EMU A;  3CIK A; 
#chains in the Genus database with same CATH homology
 5DO9 B;  3QYF A;  3NYO A;  2IHB B;  2CRP A;  2BV1 A;  5REQ B;  2GTP C;  2OWI A;  3PVW A;  2BCJ A;  2JNU A;  5HE1 A;  3C7K B;  2ODE B;  1FQK B;  2AF0 A;  1EZY A;  2BT2 A;  3PSC A;  1OMW A;  3PVU A;  2IK8 B;  2OJ4 A;  2IHD A;  3NYN A;  5HE0 A;  3V5W A;  2DLV A;  3C7L A;  4EKD B;  2V4Z B;  1AGR E;  2JM5 A;  4TND A;  1FQI A;  3UZT A;  3KRX A;  5HE2 A;  1FQJ B;  3KRW A;  4PNK A;  4TNB A;  5HE3 A;  1DK8 A;  1CMZ A;  1EZT A;  2EBZ A;  4MK0 A;  2D9J A;  1EMU A;  3CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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