3C7KB

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
120
structure length
119
Chain Sequence
VLGWRSFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(o) subunit alpha
total genus 39
structure length 119
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7kB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7kB01
1EZTA 2BV1A 2AF0A 2JM5A 2OJ4A 3KRWA 4TNBA 1FQIA 2IHDA 2V4ZB 2IK8B 3C7LA 5DO9B 4EKDB 3NYNA 1EMUA 2EBZA 3KRXA 2D9JA 2BCJA 2ODEB 4TNDA 4MK0A 3PSCA 2DLVA 3NYOA 1FQKB 3C7KB 1AGRE 1FQJB 3CIKA 2OWIA 2CRPA 2IHBB 5HE0A 5HE3A 4PNKA 3V5WA 2BT2A 5HE1A 1DK8A 1OMWA 1EZYA 1CMZA 3PVWA 2JNUA 5HE2A 3UZTA 2GTPC 3PVUA
chains in the Genus database with same CATH superfamily
1EZTA 2BV1A 2AF0A 2JM5A 2OJ4A 3QYFA 3KRWA 4TNBA 1FQIA 2IHDA 3I5QA 2V4ZB 2IK8B 3C7LA 5DO9B 4EKDB 3NYNA 1EMUA 2EBZA 3KRXA 2D9JA 4HTEA 2BCJA 2ODEB 4TNDA 4MK0A 3PSCA 2DLVA 3NYOA 1FQKB 3C7KB 1AGRE 1FQJB 5REQB 3CIKA 2OWIA 2CRPA 2IHBB 5HE0A 5HE3A 4PNKA 3V5WA 2BT2A 5HE1A 1DK8A 1OMWA 1EZYA 1CMZA 3PVWA 2JNUA 5HE2A 3UZTA 2GTPC 3PVUA
chains in the Genus database with same CATH topology
1EZTA 2BV1A 2AF0A 2JM5A 2OJ4A 3QYFA 3KRWA 4TNBA 1FQIA 2IHDA 2V4ZB 2IK8B 3C7LA 5DO9B 4EKDB 3NYNA 1EMUA 2EBZA 3KRXA 2D9JA 2BCJA 2ODEB 4TNDA 4MK0A 3PSCA 2DLVA 3NYOA 1FQKB 3C7KB 1AGRE 1FQJB 5REQB 3CIKA 2OWIA 2CRPA 2IHBB 5HE0A 5HE3A 4PNKA 3V5WA 2BT2A 5HE1A 1DK8A 1OMWA 1EZYA 1CMZA 3PVWA 2JNUA 5HE2A 3UZTA 2GTPC 3PVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZT A;  2BV1 A;  2AF0 A;  2JM5 A;  2OJ4 A;  3KRW A;  4TNB A;  1FQI A;  2IHD A;  2V4Z B;  2IK8 B;  3C7L A;  5DO9 B;  4EKD B;  3NYN A;  1EMU A;  2EBZ A;  3KRX A;  2D9J A;  2BCJ A;  2ODE B;  4TND A;  4MK0 A;  3PSC A;  2DLV A;  3NYO A;  1FQK B;  3C7K B;  1AGR E;  1FQJ B;  3CIK A;  2OWI A;  2CRP A;  2IHB B;  5HE0 A;  5HE3 A;  4PNK A;  3V5W A;  2BT2 A;  5HE1 A;  1DK8 A;  1OMW A;  1EZY A;  1CMZ A;  3PVW A;  2JNU A;  5HE2 A;  3UZT A;  2GTP C;  3PVU A; 
#chains in the Genus database with same CATH topology
 1EZT A;  2BV1 A;  2AF0 A;  2JM5 A;  2OJ4 A;  3QYF A;  3KRW A;  4TNB A;  1FQI A;  2IHD A;  3I5Q A;  2V4Z B;  2IK8 B;  3C7L A;  5DO9 B;  4EKD B;  3NYN A;  1EMU A;  2EBZ A;  3KRX A;  2D9J A;  4HTE A;  2BCJ A;  2ODE B;  4TND A;  4MK0 A;  3PSC A;  2DLV A;  3NYO A;  1FQK B;  3C7K B;  1AGR E;  1FQJ B;  5REQ B;  3CIK A;  2OWI A;  2CRP A;  2IHB B;  5HE0 A;  5HE3 A;  4PNK A;  3V5W A;  2BT2 A;  5HE1 A;  1DK8 A;  1OMW A;  1EZY A;  1CMZ A;  3PVW A;  2JNU A;  5HE2 A;  3UZT A;  2GTP C;  3PVU A; 
#chains in the Genus database with same CATH homology
 1EZT A;  2BV1 A;  2AF0 A;  2JM5 A;  2OJ4 A;  3QYF A;  3KRW A;  4TNB A;  1FQI A;  2IHD A;  2V4Z B;  2IK8 B;  3C7L A;  5DO9 B;  4EKD B;  3NYN A;  1EMU A;  2EBZ A;  3KRX A;  2D9J A;  2BCJ A;  2ODE B;  4TND A;  4MK0 A;  3PSC A;  2DLV A;  3NYO A;  1FQK B;  3C7K B;  1AGR E;  1FQJ B;  5REQ B;  3CIK A;  2OWI A;  2CRP A;  2IHB B;  5HE0 A;  5HE3 A;  4PNK A;  3V5W A;  2BT2 A;  5HE1 A;  1DK8 A;  1OMW A;  1EZY A;  1CMZ A;  3PVW A;  2JNU A;  5HE2 A;  3UZT A;  2GTP C;  3PVU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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