3C7LA

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
124
structure length
124
Chain Sequence
DVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Regulator of G-protein signaling 16
total genus 50
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7lA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7lA01
2JNUA 1EZTA 2OJ4A 2BCJA 3NYOA 3PVUA 1DK8A 4PNKA 1AGRE 1FQIA 3NYNA 1CMZA 2CRPA 1EZYA 1OMWA 3C7LA 2V4ZB 1EMUA 1FQJB 3V5WA 4EKDB 3KRWA 4TNDA 4TNBA 2IK8B 4MK0A 2D9JA 2BT2A 1FQKB 2OWIA 2JM5A 3CIKA 2AF0A 3UZTA 2BV1A 5HE3A 2IHBB 3KRXA 2EBZA 3C7KB 5HE1A 3PVWA 5HE0A 5DO9B 2ODEB 2DLVA 2GTPC 5HE2A 2IHDA 3PSCA
chains in the Genus database with same CATH superfamily
2JNUA 1EZTA 2OJ4A 2BCJA 3NYOA 3PVUA 1DK8A 4PNKA 1AGRE 1FQIA 3NYNA 1CMZA 2CRPA 1EZYA 1OMWA 3C7LA 2V4ZB 1EMUA 1FQJB 3V5WA 4EKDB 4HTEA 3KRWA 3QYFA 4TNDA 4TNBA 2IK8B 4MK0A 2D9JA 2BT2A 1FQKB 2OWIA 5REQB 2JM5A 3CIKA 2AF0A 3UZTA 2BV1A 5HE3A 2IHBB 3KRXA 2EBZA 3C7KB 3I5QA 5HE1A 3PVWA 5HE0A 5DO9B 2ODEB 2DLVA 2GTPC 5HE2A 2IHDA 3PSCA
chains in the Genus database with same CATH topology
2JNUA 1EZTA 2OJ4A 2BCJA 3NYOA 3PVUA 1DK8A 4PNKA 1AGRE 1FQIA 3NYNA 1CMZA 2CRPA 1EZYA 1OMWA 3C7LA 2V4ZB 1EMUA 1FQJB 3V5WA 4EKDB 3KRWA 3QYFA 4TNDA 4TNBA 2IK8B 4MK0A 2D9JA 2BT2A 1FQKB 2OWIA 5REQB 2JM5A 3CIKA 2AF0A 3UZTA 2BV1A 5HE3A 2IHBB 3KRXA 2EBZA 3C7KB 5HE1A 3PVWA 5HE0A 5DO9B 2ODEB 2DLVA 2GTPC 5HE2A 2IHDA 3PSCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JNU A;  1EZT A;  2OJ4 A;  2BCJ A;  3NYO A;  3PVU A;  1DK8 A;  4PNK A;  1AGR E;  1FQI A;  3NYN A;  1CMZ A;  2CRP A;  1EZY A;  1OMW A;  3C7L A;  2V4Z B;  1EMU A;  1FQJ B;  3V5W A;  4EKD B;  3KRW A;  4TND A;  4TNB A;  2IK8 B;  4MK0 A;  2D9J A;  2BT2 A;  1FQK B;  2OWI A;  2JM5 A;  3CIK A;  2AF0 A;  3UZT A;  2BV1 A;  5HE3 A;  2IHB B;  3KRX A;  2EBZ A;  3C7K B;  5HE1 A;  3PVW A;  5HE0 A;  5DO9 B;  2ODE B;  2DLV A;  2GTP C;  5HE2 A;  2IHD A;  3PSC A; 
#chains in the Genus database with same CATH topology
 2JNU A;  1EZT A;  2OJ4 A;  2BCJ A;  3NYO A;  3PVU A;  1DK8 A;  4PNK A;  1AGR E;  1FQI A;  3NYN A;  1CMZ A;  2CRP A;  1EZY A;  1OMW A;  3C7L A;  2V4Z B;  1EMU A;  1FQJ B;  3V5W A;  4EKD B;  4HTE A;  3KRW A;  3QYF A;  4TND A;  4TNB A;  2IK8 B;  4MK0 A;  2D9J A;  2BT2 A;  1FQK B;  2OWI A;  5REQ B;  2JM5 A;  3CIK A;  2AF0 A;  3UZT A;  2BV1 A;  5HE3 A;  2IHB B;  3KRX A;  2EBZ A;  3C7K B;  3I5Q A;  5HE1 A;  3PVW A;  5HE0 A;  5DO9 B;  2ODE B;  2DLV A;  2GTP C;  5HE2 A;  2IHD A;  3PSC A; 
#chains in the Genus database with same CATH homology
 2JNU A;  1EZT A;  2OJ4 A;  2BCJ A;  3NYO A;  3PVU A;  1DK8 A;  4PNK A;  1AGR E;  1FQI A;  3NYN A;  1CMZ A;  2CRP A;  1EZY A;  1OMW A;  3C7L A;  2V4Z B;  1EMU A;  1FQJ B;  3V5W A;  4EKD B;  3KRW A;  3QYF A;  4TND A;  4TNB A;  2IK8 B;  4MK0 A;  2D9J A;  2BT2 A;  1FQK B;  2OWI A;  5REQ B;  2JM5 A;  3CIK A;  2AF0 A;  3UZT A;  2BV1 A;  5HE3 A;  2IHB B;  3KRX A;  2EBZ A;  3C7K B;  5HE1 A;  3PVW A;  5HE0 A;  5DO9 B;  2ODE B;  2DLV A;  2GTP C;  5HE2 A;  2IHD A;  3PSC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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