3C7LA

Molecular architecture of galphao and the structural basis for rgs16-mediated deactivation
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
124
structure length
124
Chain Sequence
DVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular architecture of G{alpha}o and the structural basis for RGS16-mediated deactivation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Mus musculus
molecule keywords Regulator of G-protein signaling 16
total genus 50
structure length 124
sequence length 124
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 3c7lA02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 3c7lA01
2ODEB 5HE2A 3NYNA 4EKDB 1EMUA 2EBZA 5DO9B 2V4ZB 3PSCA 4TNBA 2IK8B 2BCJA 3KRXA 3CIKA 4TNDA 5HE3A 3V5WA 5HE1A 3C7LA 1EZTA 1FQKB 2OJ4A 2GTPC 2DLVA 4MK0A 5HE0A 4PNKA 1EZYA 3KRWA 3PVWA 2JM5A 2BV1A 2CRPA 1FQIA 2OWIA 1AGRE 1FQJB 2D9JA 2AF0A 2IHDA 2IHBB 1OMWA 2JNUA 1DK8A 1CMZA 2BT2A 3C7KB 3NYOA 3UZTA 3PVUA
chains in the Genus database with same CATH superfamily
3QYFA 5REQB 2ODEB 5HE2A 3NYNA 4EKDB 1EMUA 2EBZA 5DO9B 2V4ZB 3PSCA 4TNBA 2IK8B 2BCJA 3KRXA 3CIKA 4TNDA 5HE3A 3V5WA 5HE1A 3C7LA 1EZTA 1FQKB 2OJ4A 2GTPC 2DLVA 4MK0A 4HTEA 5HE0A 4PNKA 1EZYA 3KRWA 3PVWA 2JM5A 2BV1A 2CRPA 1FQIA 2OWIA 1AGRE 1FQJB 2D9JA 2AF0A 2IHDA 2IHBB 1OMWA 2JNUA 1DK8A 3I5QA 1CMZA 2BT2A 3C7KB 3NYOA 3UZTA 3PVUA
chains in the Genus database with same CATH topology
3QYFA 5REQB 2ODEB 5HE2A 3NYNA 4EKDB 1EMUA 2EBZA 5DO9B 2V4ZB 3PSCA 4TNBA 2IK8B 2BCJA 3KRXA 3CIKA 4TNDA 5HE3A 3V5WA 5HE1A 3C7LA 1EZTA 1FQKB 2OJ4A 2GTPC 2DLVA 4MK0A 5HE0A 4PNKA 1EZYA 3KRWA 3PVWA 2JM5A 2BV1A 2CRPA 1FQIA 2OWIA 1AGRE 1FQJB 2D9JA 2AF0A 2IHDA 2IHBB 1OMWA 2JNUA 1DK8A 1CMZA 2BT2A 3C7KB 3NYOA 3UZTA 3PVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ODE B;  5HE2 A;  3NYN A;  4EKD B;  1EMU A;  2EBZ A;  5DO9 B;  2V4Z B;  3PSC A;  4TNB A;  2IK8 B;  2BCJ A;  3KRX A;  3CIK A;  4TND A;  5HE3 A;  3V5W A;  5HE1 A;  3C7L A;  1EZT A;  1FQK B;  2OJ4 A;  2GTP C;  2DLV A;  4MK0 A;  5HE0 A;  4PNK A;  1EZY A;  3KRW A;  3PVW A;  2JM5 A;  2BV1 A;  2CRP A;  1FQI A;  2OWI A;  1AGR E;  1FQJ B;  2D9J A;  2AF0 A;  2IHD A;  2IHB B;  1OMW A;  2JNU A;  1DK8 A;  1CMZ A;  2BT2 A;  3C7K B;  3NYO A;  3UZT A;  3PVU A; 
#chains in the Genus database with same CATH topology
 3QYF A;  5REQ B;  2ODE B;  5HE2 A;  3NYN A;  4EKD B;  1EMU A;  2EBZ A;  5DO9 B;  2V4Z B;  3PSC A;  4TNB A;  2IK8 B;  2BCJ A;  3KRX A;  3CIK A;  4TND A;  5HE3 A;  3V5W A;  5HE1 A;  3C7L A;  1EZT A;  1FQK B;  2OJ4 A;  2GTP C;  2DLV A;  4MK0 A;  4HTE A;  5HE0 A;  4PNK A;  1EZY A;  3KRW A;  3PVW A;  2JM5 A;  2BV1 A;  2CRP A;  1FQI A;  2OWI A;  1AGR E;  1FQJ B;  2D9J A;  2AF0 A;  2IHD A;  2IHB B;  1OMW A;  2JNU A;  1DK8 A;  3I5Q A;  1CMZ A;  2BT2 A;  3C7K B;  3NYO A;  3UZT A;  3PVU A; 
#chains in the Genus database with same CATH homology
 3QYF A;  5REQ B;  2ODE B;  5HE2 A;  3NYN A;  4EKD B;  1EMU A;  2EBZ A;  5DO9 B;  2V4Z B;  3PSC A;  4TNB A;  2IK8 B;  2BCJ A;  3KRX A;  3CIK A;  4TND A;  5HE3 A;  3V5W A;  5HE1 A;  3C7L A;  1EZT A;  1FQK B;  2OJ4 A;  2GTP C;  2DLV A;  4MK0 A;  5HE0 A;  4PNK A;  1EZY A;  3KRW A;  3PVW A;  2JM5 A;  2BV1 A;  2CRP A;  1FQI A;  2OWI A;  1AGR E;  1FQJ B;  2D9J A;  2AF0 A;  2IHD A;  2IHB B;  1OMW A;  2JNU A;  1DK8 A;  1CMZ A;  2BT2 A;  3C7K B;  3NYO A;  3UZT A;  3PVU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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