3EBMA

Crystal structure of human translationally controlled tumour associated protein (htctp) mutant e12v
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
176
structure length
147
Chain Sequence
MIIYRDLISHDVMFSDIYKIREIADGLCLEVEGKMVSITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKCLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein.
pubmed doi rcsb
molecule keywords Translationally-controlled tumor protein
molecule tags Calcium-binding protein
source organism Homo sapiens
total genus 36
structure length 147
sequence length 176
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00838 TCTP Translationally controlled tumour protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.10 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3ebmA00
1HXRA 1FWQA 1H7YA 2HR9A 2FU5A 1YZ1A 2LOYA 2KWBA 1TXJA 3EBMA 3P3KA 1H6QA
chains in the Genus database with same CATH superfamily
3WX2A 4V30A 1YZ1A 5E3HA 2LOYA 5F98A 4A2VA 3HCHA 3HCJA 4V31A 3OG8A 3LRRA 3HCGA 4CI2B 5F9HA 1FWQA 2FU5A 1L1DA 2QFBA 4BPBA 2LVLA 2KWBA 3E0MA 4CI1B 3HCIA 4TZ4C 3E0OA 2RQBA 3EBMA 4V2YA 4TZCA 3EQTA 1H7YA 2HR9A 3CEZA 4AY2A 3GA3A 2YKGA 4V2ZA 2W4RA 2K8DA 4A2XA 3LRNA 2QFDA 3DJMA 3ZD7A 2RQAA 1HXRA 2KZNA 3CXKA 3MAOA 2RMJA 4CI3B 3ZD6A 3FACA 4TZUA 5F9FA 1TXJA 2KV1A 3NCUA 3WX1A 3P3KA 5AMHA 1H6QA
chains in the Genus database with same CATH topology
5F98A 1YZ1A 5E3HA 2LOYA 4A2VA 3OG8A 3LRRA 1FWQA 2FU5A 2QFBA 4BPBA 2LVLA 2KWBA 3EBMA 2RQBA 3EQTA 1H7YA 2HR9A 4AY2A 3GA3A 2YKGA 2W4RA 4A2XA 3LRNA 3DJMA 2QFDA 3ZD7A 2RQAA 1HXRA 2RMJA 3ZD6A 3FACA 5F9FA 1TXJA 5F9HA 3NCUA 3P3KA 1H6QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HXR A;  1FWQ A;  1H7Y A;  2HR9 A;  2FU5 A;  1YZ1 A;  2LOY A;  2KWB A;  1TXJ A;  3EBM A;  3P3K A;  1H6Q A; 
#chains in the Genus database with same CATH topology
 3WX2 A;  4V30 A;  1YZ1 A;  5E3H A;  2LOY A;  5F98 A;  4A2V A;  3HCH A;  3HCJ A;  4V31 A;  3OG8 A;  3LRR A;  3HCG A;  4CI2 B;  5F9H A;  1FWQ A;  2FU5 A;  1L1D A;  2QFB A;  4BPB A;  2LVL A;  2KWB A;  3E0M A;  4CI1 B;  3HCI A;  4TZ4 C;  3E0O A;  2RQB A;  3EBM A;  4V2Y A;  4TZC A;  3EQT A;  1H7Y A;  2HR9 A;  3CEZ A;  4AY2 A;  3GA3 A;  2YKG A;  4V2Z A;  2W4R A;  2K8D A;  4A2X A;  3LRN A;  2QFD A;  3DJM A;  3ZD7 A;  2RQA A;  1HXR A;  2KZN A;  3CXK A;  3MAO A;  2RMJ A;  4CI3 B;  3ZD6 A;  3FAC A;  4TZU A;  5F9F A;  1TXJ A;  2KV1 A;  3NCU A;  3WX1 A;  3P3K A;  5AMH A;  1H6Q A; 
#chains in the Genus database with same CATH homology
 5F98 A;  1YZ1 A;  5E3H A;  2LOY A;  4A2V A;  3OG8 A;  3LRR A;  1FWQ A;  2FU5 A;  2QFB A;  4BPB A;  2LVL A;  2KWB A;  3EBM A;  2RQB A;  3EQT A;  1H7Y A;  2HR9 A;  4AY2 A;  3GA3 A;  2YKG A;  2W4R A;  4A2X A;  3LRN A;  3DJM A;  2QFD A;  3ZD7 A;  2RQA A;  1HXR A;  2RMJ A;  3ZD6 A;  3FAC A;  5F9F A;  1TXJ A;  5F9H A;  3NCU A;  3P3K A;  1H6Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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