3GA3A

Crystal structure of the c-terminal domain of human mda5
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
133
structure length
133
Chain Sequence
AKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSELEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the C-terminal domain of human MDA5
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Interferon-induced helicase C domain-containing protein 1, M
total genus 28
structure length 133
sequence length 133
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-02-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3ga3A00
2RMJA 3LRNA 5F98A 3OG8A 2RQAA 2YKGA 4A2VA 5E3HA 5F9FA 4A2XA 2QFBA 4AY2A 3GA3A 2W4RA 3EQTA 3NCUA 4BPBA 2QFDA 2RQBA 3LRRA 3ZD7A 3ZD6A 5F9HA
chains in the Genus database with same CATH superfamily
1H7YA 2FU5A 4V2YA 4CI1B 3HCGA 3LRNA 1FWQA 2K8DA 3WX1A 2HR9A 5F98A 3OG8A 2RQAA 2YKGA 3E0MA 1YZ1A 4V31A 3E0OA 4A2VA 4TZCA 3HCIA 5E3HA 1H6QA 3WX2A 1TXJA 4CI2B 5F9FA 3HCJA 3DJMA 4A2XA 4TZ4C 2QFBA 1HXRA 3FACA 4AY2A 3GA3A 2LOYA 4CI3B 2W4RA 4V2ZA 3EQTA 3CXKA 3EBMA 3MAOA 4V30A 3NCUA 4BPBA 3CEZA 2QFDA 2LVLA 2KZNA 4TZUA 2RQBA 3HCHA 2KV1A 3LRRA 3P3KA 2KWBA 3ZD6A 3ZD7A 5AMHA 2RMJA 5F9HA 1L1DA
chains in the Genus database with same CATH topology
1H7YA 2FU5A 3LRNA 1FWQA 5F98A 2HR9A 3OG8A 2RQAA 2YKGA 1YZ1A 4A2VA 5E3HA 1H6QA 1TXJA 5F9FA 3DJMA 4A2XA 2QFBA 1HXRA 3FACA 4AY2A 3GA3A 2LOYA 2W4RA 3EQTA 3EBMA 3NCUA 4BPBA 2QFDA 2LVLA 2RQBA 3LRRA 3P3KA 2KWBA 3ZD6A 3ZD7A 2RMJA 5F9HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RMJ A;  3LRN A;  5F98 A;  3OG8 A;  2RQA A;  2YKG A;  4A2V A;  5E3H A;  5F9F A;  4A2X A;  2QFB A;  4AY2 A;  3GA3 A;  2W4R A;  3EQT A;  3NCU A;  4BPB A;  2QFD A;  2RQB A;  3LRR A;  3ZD7 A;  3ZD6 A;  5F9H A; 
#chains in the Genus database with same CATH topology
 1H7Y A;  2FU5 A;  4V2Y A;  4CI1 B;  3HCG A;  3LRN A;  1FWQ A;  2K8D A;  3WX1 A;  2HR9 A;  5F98 A;  3OG8 A;  2RQA A;  2YKG A;  3E0M A;  1YZ1 A;  4V31 A;  3E0O A;  4A2V A;  4TZC A;  3HCI A;  5E3H A;  1H6Q A;  3WX2 A;  1TXJ A;  4CI2 B;  5F9F A;  3HCJ A;  3DJM A;  4A2X A;  4TZ4 C;  2QFB A;  1HXR A;  3FAC A;  4AY2 A;  3GA3 A;  2LOY A;  4CI3 B;  2W4R A;  4V2Z A;  3EQT A;  3CXK A;  3EBM A;  3MAO A;  4V30 A;  3NCU A;  4BPB A;  3CEZ A;  2QFD A;  2LVL A;  2KZN A;  4TZU A;  2RQB A;  3HCH A;  2KV1 A;  3LRR A;  3P3K A;  2KWB A;  3ZD6 A;  3ZD7 A;  5AMH A;  2RMJ A;  5F9H A;  1L1D A; 
#chains in the Genus database with same CATH homology
 1H7Y A;  2FU5 A;  3LRN A;  1FWQ A;  5F98 A;  2HR9 A;  3OG8 A;  2RQA A;  2YKG A;  1YZ1 A;  4A2V A;  5E3H A;  1H6Q A;  1TXJ A;  5F9F A;  3DJM A;  4A2X A;  2QFB A;  1HXR A;  3FAC A;  4AY2 A;  3GA3 A;  2LOY A;  2W4R A;  3EQT A;  3EBM A;  3NCU A;  4BPB A;  2QFD A;  2LVL A;  2RQB A;  3LRR A;  3P3K A;  2KWB A;  3ZD6 A;  3ZD7 A;  2RMJ A;  5F9H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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