3K4FA

X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1h-1,2,4-triazol-1-yl)-2-butanone
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
214
structure length
214
Chain Sequence
PQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Heme Oxygenase Inhibition by 2-Oxy-substituted 1-Azolyl-4-phenylbutanes: Effect of Variation of the Azole Moiety. X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 4-Phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Heme oxygenase 1
total genus 80
structure length 214
sequence length 214
chains with identical sequence B
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2009-10-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 3k4fA00
4G8PA 1OTVA 3MVUA 1DVGA 1TO9B 1J2CA 1N45A 1WOXA 1P3UA 1V8XA 3B5OA 3I8RA 3NO6A 2Q4XA 1TO9A 4WX0A 1J02A 4G8UA 3IBXA 5BTQA 2DY5A 1RTWA 1IW0A 4GPHA 4MECA 1ULXA 1XK0A 4RAJA 4WD4A 1N3UA 3RM5A 1P3TA 1WNWA 4GOHA 4G8WA 4WWZA 1T5PA 1IRMA 4G98A 1TWNA 4LQXA 1P3VA 1YAKA 1SK7A 2ZVUA 3K4FA 1TWRA 1VGIA 2GM8A 1OTWA 1OZRA 4GPCA 3BJDA 3CZYA 1Z72A 2A2MA 4WWJA 1OYKA 1IVJA 2E7EA 2A2OA 1S13A 2QZCA 1XJZA 3HLXA 3I9UA 1IX3A 1XK1A 1WNXA 4G7TA 2Z68A 1S8CA 1WOVA 1IX4A 1UDDA 3HMLA 4G7PA 1UBBA 4G99A 3DDEA 3TGMA 1XK3A 4G7LA 1OZLA 1WNVA 1WZGA 1TYHA 3MOOA 4G7UA 1WOWA 2RGZA 1OZWA 4WMHA 2GM7A 2F2GA 4FN6A 1YAFA 1WWMA 1WE1A 1XK2A 3I9TA 2QCXA 1NI6A 1OYLA 2QPPA 1OZEA 3HOKA 4GPFA 1WZDA 1WZFA 1DVEA 4NY7A 1J77A 2RD3A 2A6BA 3OQLA 2Q32A 3HNHA 1RCWA 1IW1A 3B5PA
chains in the Genus database with same CATH superfamily
4G8PA 1OTVA 3MVUA 1DVGA 1TO9B 1J2CA 1N45A 1WOXA 1P3UA 1V8XA 3B5OA 3I8RA 3NO6A 2Q4XA 1TO9A 4WX0A 1J02A 4G8UA 3IBXA 5BTQA 2DY5A 1RTWA 1IW0A 4GPHA 4MECA 1ULXA 1XK0A 4RAJA 4WD4A 1N3UA 3RM5A 1P3TA 1WNWA 4GOHA 4G8WA 4WWZA 1T5PA 1IRMA 4G98A 1TWNA 4LQXA 1P3VA 1YAKA 1SK7A 2ZVUA 3K4FA 1TWRA 1VGIA 2GM8A 1OTWA 1OZRA 4GPCA 3BJDA 3CZYA 1Z72A 2A2MA 4WWJA 1OYKA 1IVJA 2E7EA 2A2OA 1S13A 2QZCA 1XJZA 3HLXA 3I9UA 1IX3A 1XK1A 1WNXA 4G7TA 2Z68A 1S8CA 1WOVA 1IX4A 1UDDA 3HMLA 4G7PA 2LCUA 1UBBA 4G99A 3DDEA 3TGMA 1XK3A 4G7LA 1OZLA 1WNVA 1WZGA 1TYHA 3MOOA 4G7UA 1WOWA 2RGZA 1OZWA 4WMHA 2GM7A 2F2GA 4FN6A 1YAFA 1WWMA 1WE1A 1XK2A 3I9TA 2QCXA 1NI6A 1OYLA 2QPPA 1OZEA 3HOKA 4GPFA 1WZDA 1WZFA 1DVEA 4NY7A 1J77A 2RD3A 2A6BA 3OQLA 2Q32A 3HNHA 1RCWA 1IW1A 3B5PA
chains in the Genus database with same CATH topology
4G8PA 1OTVA 3MVUA 1DVGA 1TO9B 1J2CA 1N45A 1WOXA 1P3UA 1V8XA 3B5OA 3I8RA 3NO6A 2Q4XA 1TO9A 4WX0A 1J02A 4G8UA 3IBXA 5BTQA 2DY5A 1RTWA 1IW0A 4GPHA 4MECA 1ULXA 1XK0A 4RAJA 4WD4A 1N3UA 3RM5A 1P3TA 1WNWA 4GOHA 4G8WA 4WWZA 1T5PA 1IRMA 4G98A 1TWNA 4LQXA 1P3VA 1YAKA 1SK7A 2ZVUA 3K4FA 1TWRA 1VGIA 2GM8A 1OTWA 1OZRA 4GPCA 3BJDA 3CZYA 1Z72A 2A2MA 4WWJA 1OYKA 1IVJA 2E7EA 2A2OA 1S13A 2QZCA 1XJZA 3HLXA 3I9UA 1IX3A 1XK1A 1WNXA 4G7TA 2Z68A 1S8CA 1WOVA 1IX4A 1UDDA 3HMLA 4G7PA 1UBBA 4G99A 3DDEA 3TGMA 1XK3A 4G7LA 1OZLA 1WNVA 1WZGA 1TYHA 3MOOA 4G7UA 1WOWA 2RGZA 1OZWA 4WMHA 2GM7A 2F2GA 4FN6A 1YAFA 1WWMA 1WE1A 1XK2A 3I9TA 2QCXA 1NI6A 1OYLA 2QPPA 1OZEA 3HOKA 4GPFA 1WZDA 1WZFA 1DVEA 4NY7A 1J77A 2RD3A 2A6BA 3OQLA 2Q32A 3HNHA 1RCWA 1IW1A 3B5PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G8P A;  1OTV A;  3MVU A;  1DVG A;  1TO9 B;  1J2C A;  1N45 A;  1WOX A;  1P3U A;  1V8X A;  3B5O A;  3I8R A;  3NO6 A;  2Q4X A;  1TO9 A;  4WX0 A;  1J02 A;  4G8U A;  3IBX A;  5BTQ A;  2DY5 A;  1RTW A;  1IW0 A;  4GPH A;  4MEC A;  1ULX A;  1XK0 A;  4RAJ A;  4WD4 A;  1N3U A;  3RM5 A;  1P3T A;  1WNW A;  4GOH A;  4G8W A;  4WWZ A;  1T5P A;  1IRM A;  4G98 A;  1TWN A;  4LQX A;  1P3V A;  1YAK A;  1SK7 A;  2ZVU A;  3K4F A;  1TWR A;  1VGI A;  2GM8 A;  1OTW A;  1OZR A;  4GPC A;  3BJD A;  3CZY A;  1Z72 A;  2A2M A;  4WWJ A;  1OYK A;  1IVJ A;  2E7E A;  2A2O A;  1S13 A;  2QZC A;  1XJZ A;  3HLX A;  3I9U A;  1IX3 A;  1XK1 A;  1WNX A;  4G7T A;  2Z68 A;  1S8C A;  1WOV A;  1IX4 A;  1UDD A;  3HML A;  4G7P A;  1UBB A;  4G99 A;  3DDE A;  3TGM A;  1XK3 A;  4G7L A;  1OZL A;  1WNV A;  1WZG A;  1TYH A;  3MOO A;  4G7U A;  1WOW A;  2RGZ A;  1OZW A;  4WMH A;  2GM7 A;  2F2G A;  4FN6 A;  1YAF A;  1WWM A;  1WE1 A;  1XK2 A;  3I9T A;  2QCX A;  1NI6 A;  1OYL A;  2QPP A;  1OZE A;  3HOK A;  4GPF A;  1WZD A;  1WZF A;  1DVE A;  4NY7 A;  1J77 A;  2RD3 A;  2A6B A;  3OQL A;  2Q32 A;  3HNH A;  1RCW A;  1IW1 A;  3B5P A; 
#chains in the Genus database with same CATH topology
 4G8P A;  1OTV A;  3MVU A;  1DVG A;  1TO9 B;  1J2C A;  1N45 A;  1WOX A;  1P3U A;  1V8X A;  3B5O A;  3I8R A;  3NO6 A;  2Q4X A;  1TO9 A;  4WX0 A;  1J02 A;  4G8U A;  3IBX A;  5BTQ A;  2DY5 A;  1RTW A;  1IW0 A;  4GPH A;  4MEC A;  1ULX A;  1XK0 A;  4RAJ A;  4WD4 A;  1N3U A;  3RM5 A;  1P3T A;  1WNW A;  4GOH A;  4G8W A;  4WWZ A;  1T5P A;  1IRM A;  4G98 A;  1TWN A;  4LQX A;  1P3V A;  1YAK A;  1SK7 A;  2ZVU A;  3K4F A;  1TWR A;  1VGI A;  2GM8 A;  1OTW A;  1OZR A;  4GPC A;  3BJD A;  3CZY A;  1Z72 A;  2A2M A;  4WWJ A;  1OYK A;  1IVJ A;  2E7E A;  2A2O A;  1S13 A;  2QZC A;  1XJZ A;  3HLX A;  3I9U A;  1IX3 A;  1XK1 A;  1WNX A;  4G7T A;  2Z68 A;  1S8C A;  1WOV A;  1IX4 A;  1UDD A;  3HML A;  4G7P A;  2LCU A;  1UBB A;  4G99 A;  3DDE A;  3TGM A;  1XK3 A;  4G7L A;  1OZL A;  1WNV A;  1WZG A;  1TYH A;  3MOO A;  4G7U A;  1WOW A;  2RGZ A;  1OZW A;  4WMH A;  2GM7 A;  2F2G A;  4FN6 A;  1YAF A;  1WWM A;  1WE1 A;  1XK2 A;  3I9T A;  2QCX A;  1NI6 A;  1OYL A;  2QPP A;  1OZE A;  3HOK A;  4GPF A;  1WZD A;  1WZF A;  1DVE A;  4NY7 A;  1J77 A;  2RD3 A;  2A6B A;  3OQL A;  2Q32 A;  3HNH A;  1RCW A;  1IW1 A;  3B5P A; 
#chains in the Genus database with same CATH homology
 4G8P A;  1OTV A;  3MVU A;  1DVG A;  1TO9 B;  1J2C A;  1N45 A;  1WOX A;  1P3U A;  1V8X A;  3B5O A;  3I8R A;  3NO6 A;  2Q4X A;  1TO9 A;  4WX0 A;  1J02 A;  4G8U A;  3IBX A;  5BTQ A;  2DY5 A;  1RTW A;  1IW0 A;  4GPH A;  4MEC A;  1ULX A;  1XK0 A;  4RAJ A;  4WD4 A;  1N3U A;  3RM5 A;  1P3T A;  1WNW A;  4GOH A;  4G8W A;  4WWZ A;  1T5P A;  1IRM A;  4G98 A;  1TWN A;  4LQX A;  1P3V A;  1YAK A;  1SK7 A;  2ZVU A;  3K4F A;  1TWR A;  1VGI A;  2GM8 A;  1OTW A;  1OZR A;  4GPC A;  3BJD A;  3CZY A;  1Z72 A;  2A2M A;  4WWJ A;  1OYK A;  1IVJ A;  2E7E A;  2A2O A;  1S13 A;  2QZC A;  1XJZ A;  3HLX A;  3I9U A;  1IX3 A;  1XK1 A;  1WNX A;  4G7T A;  2Z68 A;  1S8C A;  1WOV A;  1IX4 A;  1UDD A;  3HML A;  4G7P A;  1UBB A;  4G99 A;  3DDE A;  3TGM A;  1XK3 A;  4G7L A;  1OZL A;  1WNV A;  1WZG A;  1TYH A;  3MOO A;  4G7U A;  1WOW A;  2RGZ A;  1OZW A;  4WMH A;  2GM7 A;  2F2G A;  4FN6 A;  1YAF A;  1WWM A;  1WE1 A;  1XK2 A;  3I9T A;  2QCX A;  1NI6 A;  1OYL A;  2QPP A;  1OZE A;  3HOK A;  4GPF A;  1WZD A;  1WZF A;  1DVE A;  4NY7 A;  1J77 A;  2RD3 A;  2A6B A;  3OQL A;  2Q32 A;  3HNH A;  1RCW A;  1IW1 A;  3B5P A; 
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