3LRRA

Crystal structure of human rig-i ctd bound to a 12 bp au rich 5' ppp dsrna
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 25
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3lrrA00
5F9HA 2RMJA 4A2VA 3EQTA 3LRNA 3NCUA 3LRRA 2W4RA 5F9FA 3GA3A 3OG8A 5F98A 3ZD7A 4A2XA 2RQBA 2QFDA 4BPBA 2YKGA 2RQAA 2QFBA 5E3HA 3ZD6A 4AY2A
chains in the Genus database with same CATH superfamily
5F9HA 2RMJA 4A2VA 3EBMA 3LRNA 4TZCA 2HR9A 2KZNA 3EQTA 2K8DA 3LRRA 3NCUA 1L1DA 4CI2B 4CI1B 2LVLA 1FWQA 2W4RA 1YZ1A 5AMHA 3WX2A 4TZUA 5F9FA 4V2ZA 2KWBA 2LOYA 3HCJA 3GA3A 3WX1A 4V31A 3MAOA 3OG8A 5F98A 3ZD7A 1TXJA 1H6QA 4TZ4C 4V30A 4A2XA 3CXKA 3E0MA 2RQBA 2QFDA 2YKGA 4BPBA 2KV1A 3HCIA 3DJMA 2RQAA 2QFBA 3HCGA 5E3HA 4CI3B 1H7YA 3FACA 3P3KA 3ZD6A 4AY2A 3HCHA 1HXRA 4V2YA 2FU5A 3E0OA 3CEZA
chains in the Genus database with same CATH topology
5F9HA 2RMJA 4A2VA 3EBMA 3LRNA 3EQTA 2HR9A 3NCUA 3LRRA 2LVLA 2W4RA 1FWQA 1YZ1A 5F9FA 2KWBA 2LOYA 3GA3A 3OG8A 5F98A 3ZD7A 1TXJA 1H6QA 4A2XA 2RQBA 2QFDA 2YKGA 4BPBA 3DJMA 2RQAA 2QFBA 5E3HA 1H7YA 3FACA 3P3KA 3ZD6A 4AY2A 1HXRA 2FU5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F9H A;  2RMJ A;  4A2V A;  3EQT A;  3LRN A;  3NCU A;  3LRR A;  2W4R A;  5F9F A;  3GA3 A;  3OG8 A;  5F98 A;  3ZD7 A;  4A2X A;  2RQB A;  2QFD A;  4BPB A;  2YKG A;  2RQA A;  2QFB A;  5E3H A;  3ZD6 A;  4AY2 A; 
#chains in the Genus database with same CATH topology
 5F9H A;  2RMJ A;  4A2V A;  3EBM A;  3LRN A;  4TZC A;  2HR9 A;  2KZN A;  3EQT A;  2K8D A;  3LRR A;  3NCU A;  1L1D A;  4CI2 B;  4CI1 B;  2LVL A;  1FWQ A;  2W4R A;  1YZ1 A;  5AMH A;  3WX2 A;  4TZU A;  5F9F A;  4V2Z A;  2KWB A;  2LOY A;  3HCJ A;  3GA3 A;  3WX1 A;  4V31 A;  3MAO A;  3OG8 A;  5F98 A;  3ZD7 A;  1TXJ A;  1H6Q A;  4TZ4 C;  4V30 A;  4A2X A;  3CXK A;  3E0M A;  2RQB A;  2QFD A;  2YKG A;  4BPB A;  2KV1 A;  3HCI A;  3DJM A;  2RQA A;  2QFB A;  3HCG A;  5E3H A;  4CI3 B;  1H7Y A;  3FAC A;  3P3K A;  3ZD6 A;  4AY2 A;  3HCH A;  1HXR A;  4V2Y A;  2FU5 A;  3E0O A;  3CEZ A; 
#chains in the Genus database with same CATH homology
 5F9H A;  2RMJ A;  4A2V A;  3EBM A;  3LRN A;  3EQT A;  2HR9 A;  3NCU A;  3LRR A;  2LVL A;  2W4R A;  1FWQ A;  1YZ1 A;  5F9F A;  2KWB A;  2LOY A;  3GA3 A;  3OG8 A;  5F98 A;  3ZD7 A;  1TXJ A;  1H6Q A;  4A2X A;  2RQB A;  2QFD A;  2YKG A;  4BPB A;  3DJM A;  2RQA A;  2QFB A;  5E3H A;  1H7Y A;  3FAC A;  3P3K A;  3ZD6 A;  4AY2 A;  1HXR A;  2FU5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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