3NCUA

Structural and functional insights into pattern recognition by the innate immune receptor rig-i
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
120
structure length
120
Chain Sequence
ENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords RIG-I
total genus 27
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3ncuA00
3NCUA 2QFBA 4AY2A 5F98A 2QFDA 5F9HA 4A2VA 3EQTA 3ZD6A 5E3HA 3LRRA 5F9FA 4A2XA 2RQBA 3OG8A 3LRNA 2RMJA 4BPBA 2YKGA 2W4RA 3ZD7A 2RQAA 3GA3A
chains in the Genus database with same CATH superfamily
3E0OA 2KV1A 4CI2B 3NCUA 2QFBA 4AY2A 2FU5A 5F98A 3P3KA 2QFDA 2K8DA 3EBMA 1H6QA 3HCIA 5F9HA 4A2VA 3EQTA 2LOYA 4TZUA 1YZ1A 4V2ZA 3ZD6A 3MAOA 3FACA 4V31A 5E3HA 1TXJA 3LRRA 5F9FA 3HCJA 4V2YA 3CXKA 4A2XA 1H7YA 2RQBA 1L1DA 1FWQA 2HR9A 2KWBA 3CEZA 3DJMA 3HCHA 3HCGA 4TZ4C 3WX2A 3E0MA 3WX1A 4CI3B 4V30A 2KZNA 3OG8A 1HXRA 3LRNA 2RMJA 2LVLA 4BPBA 5AMHA 4CI1B 2YKGA 2W4RA 3ZD7A 2RQAA 4TZCA 3GA3A
chains in the Genus database with same CATH topology
3NCUA 2QFBA 4AY2A 2FU5A 5F98A 3P3KA 2QFDA 3EBMA 1H6QA 5F9HA 4A2VA 3EQTA 2LOYA 3ZD6A 1YZ1A 3FACA 5E3HA 1TXJA 3LRRA 5F9FA 4A2XA 1H7YA 2RQBA 1FWQA 2HR9A 2KWBA 3DJMA 3OG8A 1HXRA 3LRNA 2RMJA 2LVLA 4BPBA 2YKGA 2W4RA 3ZD7A 2RQAA 3GA3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NCU A;  2QFB A;  4AY2 A;  5F98 A;  2QFD A;  5F9H A;  4A2V A;  3EQT A;  3ZD6 A;  5E3H A;  3LRR A;  5F9F A;  4A2X A;  2RQB A;  3OG8 A;  3LRN A;  2RMJ A;  4BPB A;  2YKG A;  2W4R A;  3ZD7 A;  2RQA A;  3GA3 A; 
#chains in the Genus database with same CATH topology
 3E0O A;  2KV1 A;  4CI2 B;  3NCU A;  2QFB A;  4AY2 A;  2FU5 A;  5F98 A;  3P3K A;  2QFD A;  2K8D A;  3EBM A;  1H6Q A;  3HCI A;  5F9H A;  4A2V A;  3EQT A;  2LOY A;  4TZU A;  1YZ1 A;  4V2Z A;  3ZD6 A;  3MAO A;  3FAC A;  4V31 A;  5E3H A;  1TXJ A;  3LRR A;  5F9F A;  3HCJ A;  4V2Y A;  3CXK A;  4A2X A;  1H7Y A;  2RQB A;  1L1D A;  1FWQ A;  2HR9 A;  2KWB A;  3CEZ A;  3DJM A;  3HCH A;  3HCG A;  4TZ4 C;  3WX2 A;  3E0M A;  3WX1 A;  4CI3 B;  4V30 A;  2KZN A;  3OG8 A;  1HXR A;  3LRN A;  2RMJ A;  2LVL A;  4BPB A;  5AMH A;  4CI1 B;  2YKG A;  2W4R A;  3ZD7 A;  2RQA A;  4TZC A;  3GA3 A; 
#chains in the Genus database with same CATH homology
 3NCU A;  2QFB A;  4AY2 A;  2FU5 A;  5F98 A;  3P3K A;  2QFD A;  3EBM A;  1H6Q A;  5F9H A;  4A2V A;  3EQT A;  2LOY A;  3ZD6 A;  1YZ1 A;  3FAC A;  5E3H A;  1TXJ A;  3LRR A;  5F9F A;  4A2X A;  1H7Y A;  2RQB A;  1FWQ A;  2HR9 A;  2KWB A;  3DJM A;  3OG8 A;  1HXR A;  3LRN A;  2RMJ A;  2LVL A;  4BPB A;  2YKG A;  2W4R A;  3ZD7 A;  2RQA A;  3GA3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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