3GA3A

Crystal structure of the c-terminal domain of human mda5
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
133
structure length
133
Chain Sequence
AKHYKNNPSLITFLCKNCSVLACSGEDIHVIEKMHHVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSELEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the C-terminal domain of human MDA5
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Interferon-induced helicase C domain-containing protein 1, M
total genus 28
structure length 133
sequence length 133
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2009-02-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3ga3A00
3NCUA 3ZD7A 4BPBA 2RQAA 2RQBA 2RMJA 5F9HA 4A2XA 3ZD6A 4AY2A 2W4RA 2QFBA 5E3HA 3OG8A 5F98A 3EQTA 2YKGA 3LRNA 5F9FA 3GA3A 4A2VA 2QFDA 3LRRA
chains in the Genus database with same CATH superfamily
3HCJA 3NCUA 3ZD7A 3CXKA 3WX2A 4BPBA 2RQAA 4CI1B 2RQBA 3HCGA 1H6QA 2RMJA 1TXJA 2KWBA 3CEZA 5F9HA 4A2XA 4CI2B 3DJMA 3ZD6A 2K8DA 4AY2A 2W4RA 3FACA 4CI3B 2KV1A 2QFBA 5E3HA 4V2YA 3OG8A 3MAOA 3HCHA 4TZ4C 2KZNA 3HCIA 4V30A 3EBMA 5F98A 3EQTA 1HXRA 1FWQA 2YKGA 3LRNA 1YZ1A 1L1DA 4TZUA 3E0MA 2LVLA 3E0OA 2FU5A 5F9FA 1H7YA 3GA3A 3P3KA 4V31A 3WX1A 4A2VA 2HR9A 2QFDA 4V2ZA 3LRRA 2LOYA 4TZCA 5AMHA
chains in the Genus database with same CATH topology
3NCUA 3ZD7A 4BPBA 2RQAA 2RQBA 1H6QA 2RMJA 1TXJA 2KWBA 5F9HA 4A2XA 3DJMA 3ZD6A 4AY2A 2W4RA 3FACA 2QFBA 5E3HA 3OG8A 5F98A 3EBMA 3EQTA 1HXRA 1FWQA 2YKGA 3LRNA 1YZ1A 2LVLA 2FU5A 5F9FA 1H7YA 3GA3A 3P3KA 4A2VA 2HR9A 2QFDA 3LRRA 2LOYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NCU A;  3ZD7 A;  4BPB A;  2RQA A;  2RQB A;  2RMJ A;  5F9H A;  4A2X A;  3ZD6 A;  4AY2 A;  2W4R A;  2QFB A;  5E3H A;  3OG8 A;  5F98 A;  3EQT A;  2YKG A;  3LRN A;  5F9F A;  3GA3 A;  4A2V A;  2QFD A;  3LRR A; 
#chains in the Genus database with same CATH topology
 3HCJ A;  3NCU A;  3ZD7 A;  3CXK A;  3WX2 A;  4BPB A;  2RQA A;  4CI1 B;  2RQB A;  3HCG A;  1H6Q A;  2RMJ A;  1TXJ A;  2KWB A;  3CEZ A;  5F9H A;  4A2X A;  4CI2 B;  3DJM A;  3ZD6 A;  2K8D A;  4AY2 A;  2W4R A;  3FAC A;  4CI3 B;  2KV1 A;  2QFB A;  5E3H A;  4V2Y A;  3OG8 A;  3MAO A;  3HCH A;  4TZ4 C;  2KZN A;  3HCI A;  4V30 A;  3EBM A;  5F98 A;  3EQT A;  1HXR A;  1FWQ A;  2YKG A;  3LRN A;  1YZ1 A;  1L1D A;  4TZU A;  3E0M A;  2LVL A;  3E0O A;  2FU5 A;  5F9F A;  1H7Y A;  3GA3 A;  3P3K A;  4V31 A;  3WX1 A;  4A2V A;  2HR9 A;  2QFD A;  4V2Z A;  3LRR A;  2LOY A;  4TZC A;  5AMH A; 
#chains in the Genus database with same CATH homology
 3NCU A;  3ZD7 A;  4BPB A;  2RQA A;  2RQB A;  1H6Q A;  2RMJ A;  1TXJ A;  2KWB A;  5F9H A;  4A2X A;  3DJM A;  3ZD6 A;  4AY2 A;  2W4R A;  3FAC A;  2QFB A;  5E3H A;  3OG8 A;  5F98 A;  3EBM A;  3EQT A;  1HXR A;  1FWQ A;  2YKG A;  3LRN A;  1YZ1 A;  2LVL A;  2FU5 A;  5F9F A;  1H7Y A;  3GA3 A;  3P3K A;  4A2V A;  2HR9 A;  2QFD A;  3LRR A;  2LOY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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