3LRNA

Crystal structure of human rig-i ctd bound to a 14 bp gc 5' ppp dsrna
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 26
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3lrnA00
3LRRA 3GA3A 5E3HA 3OG8A 2QFBA 3ZD6A 5F98A 5F9HA 3EQTA 2YKGA 3LRNA 2RQAA 2W4RA 4A2VA 2QFDA 4BPBA 5F9FA 3ZD7A 2RQBA 3NCUA 2RMJA 4A2XA 4AY2A
chains in the Genus database with same CATH superfamily
2HR9A 3GA3A 5AMHA 2LVLA 3LRRA 3HCJA 3CEZA 4V31A 4CI1B 4V2YA 5E3HA 3OG8A 3WX2A 2QFBA 2KWBA 1L1DA 3ZD6A 3HCIA 5F9HA 5F98A 3DJMA 3HCHA 1FWQA 3CXKA 3E0OA 4TZCA 3FACA 3EQTA 4A2XA 1TXJA 1YZ1A 2YKGA 3LRNA 2K8DA 3HCGA 2RQAA 1HXRA 4CI2B 2FU5A 2KV1A 3MAOA 2W4RA 4A2VA 2QFDA 1H6QA 2KZNA 4CI3B 3P3KA 4TZUA 2LOYA 4BPBA 4V2ZA 5F9FA 3WX1A 3ZD7A 2RQBA 3NCUA 3EBMA 4V30A 1H7YA 2RMJA 4TZ4C 4AY2A 3E0MA
chains in the Genus database with same CATH topology
2HR9A 3GA3A 3LRRA 2LVLA 5E3HA 3OG8A 2QFBA 2KWBA 3ZD6A 5F98A 5F9HA 3DJMA 1FWQA 3FACA 3EQTA 1TXJA 1YZ1A 2YKGA 3LRNA 2RQAA 1HXRA 2FU5A 2W4RA 4A2VA 2QFDA 1H6QA 3P3KA 2LOYA 4BPBA 5F9FA 3ZD7A 2RQBA 3NCUA 3EBMA 1H7YA 2RMJA 4A2XA 4AY2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LRR A;  3GA3 A;  5E3H A;  3OG8 A;  2QFB A;  3ZD6 A;  5F98 A;  5F9H A;  3EQT A;  2YKG A;  3LRN A;  2RQA A;  2W4R A;  4A2V A;  2QFD A;  4BPB A;  5F9F A;  3ZD7 A;  2RQB A;  3NCU A;  2RMJ A;  4A2X A;  4AY2 A; 
#chains in the Genus database with same CATH topology
 2HR9 A;  3GA3 A;  5AMH A;  2LVL A;  3LRR A;  3HCJ A;  3CEZ A;  4V31 A;  4CI1 B;  4V2Y A;  5E3H A;  3OG8 A;  3WX2 A;  2QFB A;  2KWB A;  1L1D A;  3ZD6 A;  3HCI A;  5F9H A;  5F98 A;  3DJM A;  3HCH A;  1FWQ A;  3CXK A;  3E0O A;  4TZC A;  3FAC A;  3EQT A;  4A2X A;  1TXJ A;  1YZ1 A;  2YKG A;  3LRN A;  2K8D A;  3HCG A;  2RQA A;  1HXR A;  4CI2 B;  2FU5 A;  2KV1 A;  3MAO A;  2W4R A;  4A2V A;  2QFD A;  1H6Q A;  2KZN A;  4CI3 B;  3P3K A;  4TZU A;  2LOY A;  4BPB A;  4V2Z A;  5F9F A;  3WX1 A;  3ZD7 A;  2RQB A;  3NCU A;  3EBM A;  4V30 A;  1H7Y A;  2RMJ A;  4TZ4 C;  4AY2 A;  3E0M A; 
#chains in the Genus database with same CATH homology
 2HR9 A;  3GA3 A;  3LRR A;  2LVL A;  5E3H A;  3OG8 A;  2QFB A;  2KWB A;  3ZD6 A;  5F98 A;  5F9H A;  3DJM A;  1FWQ A;  3FAC A;  3EQT A;  1TXJ A;  1YZ1 A;  2YKG A;  3LRN A;  2RQA A;  1HXR A;  2FU5 A;  2W4R A;  4A2V A;  2QFD A;  1H6Q A;  3P3K A;  2LOY A;  4BPB A;  5F9F A;  3ZD7 A;  2RQB A;  3NCU A;  3EBM A;  1H7Y A;  2RMJ A;  4A2X A;  4AY2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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