3LRRA

Crystal structure of human rig-i ctd bound to a 12 bp au rich 5' ppp dsrna
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
121
structure length
121
Chain Sequence
KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Probable ATP-dependent RNA helicase DDX58
total genus 25
structure length 121
sequence length 121
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3lrrA00
3ZD6A 2W4RA 2RQAA 3EQTA 4AY2A 2QFBA 3GA3A 4A2XA 5F98A 5F9HA 3LRNA 4BPBA 4A2VA 3ZD7A 5F9FA 2QFDA 2RQBA 2YKGA 3LRRA 2RMJA 3OG8A 3NCUA 5E3HA
chains in the Genus database with same CATH superfamily
3ZD6A 2W4RA 4TZ4C 2RQAA 1L1DA 1H7YA 3EQTA 3HCHA 4AY2A 2QFBA 4CI2B 2KZNA 3GA3A 2KV1A 3MAOA 4CI1B 2LOYA 4V2YA 4A2XA 4V31A 4V2ZA 5F98A 3HCJA 5F9HA 3LRNA 5AMHA 4V30A 4A2VA 4BPBA 2KWBA 3ZD7A 5F9FA 2FU5A 2QFDA 4CI3B 2K8DA 2LVLA 3CEZA 3CXKA 2RQBA 3P3KA 2YKGA 2RMJA 3WX2A 3E0MA 1FWQA 3HCGA 3E0OA 3HCIA 1H6QA 3LRRA 3OG8A 3NCUA 1HXRA 3DJMA 3EBMA 4TZCA 4TZUA 1YZ1A 1TXJA 3FACA 3WX1A 2HR9A 5E3HA
chains in the Genus database with same CATH topology
3ZD6A 2W4RA 2RQAA 1H7YA 3EQTA 4AY2A 2QFBA 3GA3A 2LOYA 4A2XA 5F98A 5F9HA 3LRNA 4BPBA 4A2VA 2KWBA 3ZD7A 5F9FA 2FU5A 2QFDA 2LVLA 2RQBA 3P3KA 2YKGA 2RMJA 3LRRA 1FWQA 3OG8A 1H6QA 3NCUA 1HXRA 3DJMA 3EBMA 1YZ1A 1TXJA 3FACA 2HR9A 5E3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZD6 A;  2W4R A;  2RQA A;  3EQT A;  4AY2 A;  2QFB A;  3GA3 A;  4A2X A;  5F98 A;  5F9H A;  3LRN A;  4BPB A;  4A2V A;  3ZD7 A;  5F9F A;  2QFD A;  2RQB A;  2YKG A;  3LRR A;  2RMJ A;  3OG8 A;  3NCU A;  5E3H A; 
#chains in the Genus database with same CATH topology
 3ZD6 A;  2W4R A;  4TZ4 C;  2RQA A;  1L1D A;  1H7Y A;  3EQT A;  3HCH A;  4AY2 A;  2QFB A;  4CI2 B;  2KZN A;  3GA3 A;  2KV1 A;  3MAO A;  4CI1 B;  2LOY A;  4V2Y A;  4A2X A;  4V31 A;  4V2Z A;  5F98 A;  3HCJ A;  5F9H A;  3LRN A;  5AMH A;  4V30 A;  4A2V A;  4BPB A;  2KWB A;  3ZD7 A;  5F9F A;  2FU5 A;  2QFD A;  4CI3 B;  2K8D A;  2LVL A;  3CEZ A;  3CXK A;  2RQB A;  3P3K A;  2YKG A;  2RMJ A;  3WX2 A;  3E0M A;  1FWQ A;  3HCG A;  3E0O A;  3HCI A;  1H6Q A;  3LRR A;  3OG8 A;  3NCU A;  1HXR A;  3DJM A;  3EBM A;  4TZC A;  4TZU A;  1YZ1 A;  1TXJ A;  3FAC A;  3WX1 A;  2HR9 A;  5E3H A; 
#chains in the Genus database with same CATH homology
 3ZD6 A;  2W4R A;  2RQA A;  1H7Y A;  3EQT A;  4AY2 A;  2QFB A;  3GA3 A;  2LOY A;  4A2X A;  5F98 A;  5F9H A;  3LRN A;  4BPB A;  4A2V A;  2KWB A;  3ZD7 A;  5F9F A;  2FU5 A;  2QFD A;  2LVL A;  2RQB A;  3P3K A;  2YKG A;  2RMJ A;  3LRR A;  1FWQ A;  3OG8 A;  1H6Q A;  3NCU A;  1HXR A;  3DJM A;  3EBM A;  1YZ1 A;  1TXJ A;  3FAC A;  2HR9 A;  5E3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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