3NCUA

Structural and functional insights into pattern recognition by the innate immune receptor rig-i
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
120
structure length
120
Chain Sequence
ENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPKQFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQTLYSKWKDFHFEKIPFDPAEM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords RIG-I
total genus 27
structure length 120
sequence length 120
chains with identical sequence B
ec nomenclature ec 3.6.4.13: RNA helicase.
pdb deposition date 2010-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11648 RIG-I_C-RD C-terminal domain of RIG-I
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.30 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 3ncuA00
5F9FA 4BPBA 2YKGA 2QFBA 2RQAA 2W4RA 3NCUA 3LRRA 3EQTA 5F9HA 2RQBA 5F98A 2QFDA 3LRNA 3GA3A 5E3HA 3OG8A 3ZD6A 4A2VA 2RMJA 4A2XA 4AY2A 3ZD7A
chains in the Genus database with same CATH superfamily
3CXKA 1FWQA 5F9FA 3DJMA 3HCGA 4BPBA 3MAOA 2YKGA 1HXRA 2QFBA 2RQAA 2W4RA 4CI1B 3NCUA 2KV1A 3HCJA 4V30A 3WX1A 3LRRA 2KWBA 2LOYA 1YZ1A 4TZUA 3EQTA 3EBMA 2FU5A 4V31A 3E0OA 5F9HA 3FACA 3P3KA 2RQBA 3WX2A 1L1DA 5F98A 4V2ZA 4V2YA 4CI3B 3E0MA 3HCIA 3CEZA 2QFDA 1TXJA 3LRNA 3ZD7A 3GA3A 3HCHA 5E3HA 3OG8A 2K8DA 4CI2B 4A2VA 3ZD6A 4AY2A 2KZNA 2LVLA 1H7YA 2HR9A 2RMJA 4A2XA 5AMHA 4TZ4C 1H6QA 4TZCA
chains in the Genus database with same CATH topology
1FWQA 5F9FA 3DJMA 4BPBA 2YKGA 1HXRA 2QFBA 2RQAA 2W4RA 3NCUA 3LRRA 2KWBA 2LOYA 1YZ1A 3EQTA 3EBMA 2FU5A 5F9HA 3FACA 3P3KA 2RQBA 5F98A 2QFDA 1TXJA 3LRNA 3ZD7A 3GA3A 5E3HA 3OG8A 3ZD6A 1H7YA 4A2VA 2LVLA 2HR9A 2RMJA 4A2XA 4AY2A 1H6QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F9F A;  4BPB A;  2YKG A;  2QFB A;  2RQA A;  2W4R A;  3NCU A;  3LRR A;  3EQT A;  5F9H A;  2RQB A;  5F98 A;  2QFD A;  3LRN A;  3GA3 A;  5E3H A;  3OG8 A;  3ZD6 A;  4A2V A;  2RMJ A;  4A2X A;  4AY2 A;  3ZD7 A; 
#chains in the Genus database with same CATH topology
 3CXK A;  1FWQ A;  5F9F A;  3DJM A;  3HCG A;  4BPB A;  3MAO A;  2YKG A;  1HXR A;  2QFB A;  2RQA A;  2W4R A;  4CI1 B;  3NCU A;  2KV1 A;  3HCJ A;  4V30 A;  3WX1 A;  3LRR A;  2KWB A;  2LOY A;  1YZ1 A;  4TZU A;  3EQT A;  3EBM A;  2FU5 A;  4V31 A;  3E0O A;  5F9H A;  3FAC A;  3P3K A;  2RQB A;  3WX2 A;  1L1D A;  5F98 A;  4V2Z A;  4V2Y A;  4CI3 B;  3E0M A;  3HCI A;  3CEZ A;  2QFD A;  1TXJ A;  3LRN A;  3ZD7 A;  3GA3 A;  3HCH A;  5E3H A;  3OG8 A;  2K8D A;  4CI2 B;  4A2V A;  3ZD6 A;  4AY2 A;  2KZN A;  2LVL A;  1H7Y A;  2HR9 A;  2RMJ A;  4A2X A;  5AMH A;  4TZ4 C;  1H6Q A;  4TZC A; 
#chains in the Genus database with same CATH homology
 1FWQ A;  5F9F A;  3DJM A;  4BPB A;  2YKG A;  1HXR A;  2QFB A;  2RQA A;  2W4R A;  3NCU A;  3LRR A;  2KWB A;  2LOY A;  1YZ1 A;  3EQT A;  3EBM A;  2FU5 A;  5F9H A;  3FAC A;  3P3K A;  2RQB A;  5F98 A;  2QFD A;  1TXJ A;  3LRN A;  3ZD7 A;  3GA3 A;  5E3H A;  3OG8 A;  3ZD6 A;  1H7Y A;  4A2V A;  2LVL A;  2HR9 A;  2RMJ A;  4A2X A;  4AY2 A;  1H6Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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