4EKDB

Structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
132
structure length
132
Chain Sequence
FGSPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
pubmed doi rcsb
molecule tags Signaling protein/inhibitor
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
total genus 43
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2012-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 4ekdB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 4ekdB01
1OMWA 2OWIA 4EKDB 5HE2A 2IHBB 3KRWA 3PVUA 3PSCA 1EZYA 3UZTA 3C7KB 2JNUA 1CMZA 1FQKB 2IK8B 1FQIA 1FQJB 2AF0A 3NYNA 2BCJA 3C7LA 3V5WA 2OJ4A 2BV1A 2ODEB 2EBZA 3CIKA 5HE3A 4TNDA 4TNBA 4MK0A 1EZTA 4PNKA 3NYOA 1EMUA 2IHDA 2JM5A 5DO9B 5HE0A 3PVWA 1DK8A 2GTPC 2D9JA 2BT2A 2DLVA 2V4ZB 5HE1A 1AGRE 3KRXA 2CRPA
chains in the Genus database with same CATH superfamily
3QYFA 1OMWA 2OWIA 4EKDB 5HE2A 2IHBB 3KRWA 3PVUA 3I5QA 3PSCA 1EZYA 3UZTA 3C7KB 2JNUA 1CMZA 1FQKB 2IK8B 1FQIA 1FQJB 2AF0A 3NYNA 2BCJA 3C7LA 3V5WA 5REQB 2OJ4A 2BV1A 2ODEB 2EBZA 3CIKA 5HE3A 4TNDA 4TNBA 4MK0A 1EZTA 4PNKA 3NYOA 1EMUA 2IHDA 2JM5A 5DO9B 5HE0A 3PVWA 1DK8A 2GTPC 2D9JA 2BT2A 2DLVA 2V4ZB 4HTEA 5HE1A 1AGRE 3KRXA 2CRPA
chains in the Genus database with same CATH topology
3QYFA 1OMWA 2OWIA 4EKDB 5HE2A 2IHBB 3KRWA 3PVUA 3PSCA 1EZYA 3UZTA 3C7KB 2JNUA 1CMZA 1FQKB 2IK8B 1FQIA 1FQJB 2AF0A 3NYNA 2BCJA 3C7LA 3V5WA 5REQB 2OJ4A 2BV1A 2ODEB 2EBZA 3CIKA 5HE3A 4TNDA 4TNBA 4MK0A 1EZTA 4PNKA 3NYOA 1EMUA 2IHDA 2JM5A 5DO9B 5HE0A 3PVWA 1DK8A 2GTPC 2D9JA 2BT2A 2DLVA 2V4ZB 5HE1A 1AGRE 3KRXA 2CRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OMW A;  2OWI A;  4EKD B;  5HE2 A;  2IHB B;  3KRW A;  3PVU A;  3PSC A;  1EZY A;  3UZT A;  3C7K B;  2JNU A;  1CMZ A;  1FQK B;  2IK8 B;  1FQI A;  1FQJ B;  2AF0 A;  3NYN A;  2BCJ A;  3C7L A;  3V5W A;  2OJ4 A;  2BV1 A;  2ODE B;  2EBZ A;  3CIK A;  5HE3 A;  4TND A;  4TNB A;  4MK0 A;  1EZT A;  4PNK A;  3NYO A;  1EMU A;  2IHD A;  2JM5 A;  5DO9 B;  5HE0 A;  3PVW A;  1DK8 A;  2GTP C;  2D9J A;  2BT2 A;  2DLV A;  2V4Z B;  5HE1 A;  1AGR E;  3KRX A;  2CRP A; 
#chains in the Genus database with same CATH topology
 3QYF A;  1OMW A;  2OWI A;  4EKD B;  5HE2 A;  2IHB B;  3KRW A;  3PVU A;  3I5Q A;  3PSC A;  1EZY A;  3UZT A;  3C7K B;  2JNU A;  1CMZ A;  1FQK B;  2IK8 B;  1FQI A;  1FQJ B;  2AF0 A;  3NYN A;  2BCJ A;  3C7L A;  3V5W A;  5REQ B;  2OJ4 A;  2BV1 A;  2ODE B;  2EBZ A;  3CIK A;  5HE3 A;  4TND A;  4TNB A;  4MK0 A;  1EZT A;  4PNK A;  3NYO A;  1EMU A;  2IHD A;  2JM5 A;  5DO9 B;  5HE0 A;  3PVW A;  1DK8 A;  2GTP C;  2D9J A;  2BT2 A;  2DLV A;  2V4Z B;  4HTE A;  5HE1 A;  1AGR E;  3KRX A;  2CRP A; 
#chains in the Genus database with same CATH homology
 3QYF A;  1OMW A;  2OWI A;  4EKD B;  5HE2 A;  2IHB B;  3KRW A;  3PVU A;  3PSC A;  1EZY A;  3UZT A;  3C7K B;  2JNU A;  1CMZ A;  1FQK B;  2IK8 B;  1FQI A;  1FQJ B;  2AF0 A;  3NYN A;  2BCJ A;  3C7L A;  3V5W A;  5REQ B;  2OJ4 A;  2BV1 A;  2ODE B;  2EBZ A;  3CIK A;  5HE3 A;  4TND A;  4TNB A;  4MK0 A;  1EZT A;  4PNK A;  3NYO A;  1EMU A;  2IHD A;  2JM5 A;  5DO9 B;  5HE0 A;  3PVW A;  1DK8 A;  2GTP C;  2D9J A;  2BT2 A;  2DLV A;  2V4Z B;  5HE1 A;  1AGR E;  3KRX A;  2CRP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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