4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
1WOXA 3CZYA 3I8RA 1S13A 1TO9B 1XK3A 1ULXA 1J77A 1WZFA 2A2MA 4G7TA 4FN6A 2RGZA 4WWJA 1NI6A 2Q4XA 1J2CA 1UBBA 1UDDA 1YAKA 4G7UA 2Q32A 3MVUA 3OQLA 1RTWA 4GOHA 1WZGA 4G8UA 4WX0A 1OTVA 2QZCA 5BTQA 2QPPA 1TWNA 1J02A 2GM8A 1IX4A 1WZDA 1YAFA 2QCXA 1XK1A 1WOVA 1XK0A 4LQXA 4RAJA 3DDEA 4G7LA 1WWMA 3K4FA 1IRMA 3HLXA 1T5PA 2F2GA 2GM7A 1OTWA 1P3TA 3B5OA 1DVEA 4NY7A 1OZRA 2RD3A 4WD4A 1OZEA 2A2OA 2DY5A 4WMHA 2ZVUA 1V8XA 3TGMA 3B5PA 1OYKA 1XJZA 4G7PA 3RM5A 2E7EA 1N45A 3I9TA 1WNVA 1Z72A 4GPFA 1SK7A 4G98A 1WNXA 3I9UA 2Z68A 3MOOA 1P3UA 1TYHA 4G8PA 4GPCA 3HNHA 3NO6A 1N3UA 4G99A 1DVGA 4GPHA 4MECA 4WWZA 1IX3A 3HMLA 1IW1A 3HOKA 1OYLA 1XK2A 1VGIA 1WNWA 3IBXA 1S8CA 1IW0A 3BJDA 1WE1A 1P3VA 1TO9A 1IVJA 1TWRA 1WOWA 1OZWA 1RCWA 2A6BA 1OZLA 4G8WA
chains in the Genus database with same CATH superfamily
1WOXA 3CZYA 3I8RA 1S13A 1TO9B 1XK3A 1ULXA 1J77A 1WZFA 2A2MA 4G7TA 4FN6A 2RGZA 4WWJA 1NI6A 2Q4XA 1J2CA 1UBBA 1UDDA 1YAKA 4G7UA 2LCUA 2Q32A 3MVUA 3OQLA 1RTWA 4GOHA 1WZGA 4G8UA 4WX0A 1OTVA 2QZCA 5BTQA 2QPPA 1TWNA 1J02A 2GM8A 1IX4A 1WZDA 1YAFA 2QCXA 1XK1A 1WOVA 1XK0A 4LQXA 4RAJA 3DDEA 4G7LA 1WWMA 3K4FA 1IRMA 3HLXA 1T5PA 2F2GA 2GM7A 1OTWA 1P3TA 3B5OA 1DVEA 4NY7A 1OZRA 2RD3A 4WD4A 1OZEA 2A2OA 2DY5A 4WMHA 2ZVUA 1V8XA 3TGMA 3B5PA 1OYKA 1XJZA 4G7PA 3RM5A 2E7EA 1N45A 3I9TA 1WNVA 1Z72A 4GPFA 1SK7A 4G98A 1WNXA 3I9UA 2Z68A 3MOOA 1P3UA 1TYHA 4G8PA 4GPCA 3HNHA 3NO6A 1N3UA 4G99A 1DVGA 4GPHA 4MECA 4WWZA 1IX3A 3HMLA 1IW1A 3HOKA 1OYLA 1XK2A 1VGIA 1WNWA 3IBXA 1S8CA 1IW0A 3BJDA 1WE1A 1P3VA 1TO9A 1IVJA 1TWRA 1WOWA 1OZWA 1RCWA 2A6BA 1OZLA 4G8WA
chains in the Genus database with same CATH topology
1WOXA 3CZYA 3I8RA 1S13A 1TO9B 1XK3A 1ULXA 1J77A 1WZFA 2A2MA 4G7TA 4FN6A 2RGZA 4WWJA 1NI6A 2Q4XA 1J2CA 1UBBA 1UDDA 1YAKA 4G7UA 2Q32A 3MVUA 3OQLA 1RTWA 4GOHA 1WZGA 4G8UA 4WX0A 1OTVA 2QZCA 5BTQA 2QPPA 1TWNA 1J02A 2GM8A 1IX4A 1WZDA 1YAFA 2QCXA 1XK1A 1WOVA 1XK0A 4LQXA 4RAJA 3DDEA 4G7LA 1WWMA 3K4FA 1IRMA 3HLXA 1T5PA 2F2GA 2GM7A 1OTWA 1P3TA 3B5OA 1DVEA 4NY7A 1OZRA 2RD3A 4WD4A 1OZEA 2A2OA 2DY5A 4WMHA 2ZVUA 1V8XA 3TGMA 3B5PA 1OYKA 1XJZA 4G7PA 3RM5A 2E7EA 1N45A 3I9TA 1WNVA 1Z72A 4GPFA 1SK7A 4G98A 1WNXA 3I9UA 2Z68A 3MOOA 1P3UA 1TYHA 4G8PA 4GPCA 3HNHA 3NO6A 1N3UA 4G99A 1DVGA 4GPHA 4MECA 4WWZA 1IX3A 3HMLA 1IW1A 3HOKA 1OYLA 1XK2A 1VGIA 1WNWA 3IBXA 1S8CA 1IW0A 3BJDA 1WE1A 1P3VA 1TO9A 1IVJA 1TWRA 1WOWA 1OZWA 1RCWA 2A6BA 1OZLA 4G8WA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1WOX A;  3CZY A;  3I8R A;  1S13 A;  1TO9 B;  1XK3 A;  1ULX A;  1J77 A;  1WZF A;  2A2M A;  4G7T A;  4FN6 A;  2RGZ A;  4WWJ A;  1NI6 A;  2Q4X A;  1J2C A;  1UBB A;  1UDD A;  1YAK A;  4G7U A;  2Q32 A;  3MVU A;  3OQL A;  1RTW A;  4GOH A;  1WZG A;  4G8U A;  4WX0 A;  1OTV A;  2QZC A;  5BTQ A;  2QPP A;  1TWN A;  1J02 A;  2GM8 A;  1IX4 A;  1WZD A;  1YAF A;  2QCX A;  1XK1 A;  1WOV A;  1XK0 A;  4LQX A;  4RAJ A;  3DDE A;  4G7L A;  1WWM A;  3K4F A;  1IRM A;  3HLX A;  1T5P A;  2F2G A;  2GM7 A;  1OTW A;  1P3T A;  3B5O A;  1DVE A;  4NY7 A;  1OZR A;  2RD3 A;  4WD4 A;  1OZE A;  2A2O A;  2DY5 A;  4WMH A;  2ZVU A;  1V8X A;  3TGM A;  3B5P A;  1OYK A;  1XJZ A;  4G7P A;  3RM5 A;  2E7E A;  1N45 A;  3I9T A;  1WNV A;  1Z72 A;  4GPF A;  1SK7 A;  4G98 A;  1WNX A;  3I9U A;  2Z68 A;  3MOO A;  1P3U A;  1TYH A;  4G8P A;  4GPC A;  3HNH A;  3NO6 A;  1N3U A;  4G99 A;  1DVG A;  4GPH A;  4MEC A;  4WWZ A;  1IX3 A;  3HML A;  1IW1 A;  3HOK A;  1OYL A;  1XK2 A;  1VGI A;  1WNW A;  3IBX A;  1S8C A;  1IW0 A;  3BJD A;  1WE1 A;  1P3V A;  1TO9 A;  1IVJ A;  1TWR A;  1WOW A;  1OZW A;  1RCW A;  2A6B A;  1OZL A;  4G8W A; 
#chains in the Genus database with same CATH topology
 1WOX A;  3CZY A;  3I8R A;  1S13 A;  1TO9 B;  1XK3 A;  1ULX A;  1J77 A;  1WZF A;  2A2M A;  4G7T A;  4FN6 A;  2RGZ A;  4WWJ A;  1NI6 A;  2Q4X A;  1J2C A;  1UBB A;  1UDD A;  1YAK A;  4G7U A;  2LCU A;  2Q32 A;  3MVU A;  3OQL A;  1RTW A;  4GOH A;  1WZG A;  4G8U A;  4WX0 A;  1OTV A;  2QZC A;  5BTQ A;  2QPP A;  1TWN A;  1J02 A;  2GM8 A;  1IX4 A;  1WZD A;  1YAF A;  2QCX A;  1XK1 A;  1WOV A;  1XK0 A;  4LQX A;  4RAJ A;  3DDE A;  4G7L A;  1WWM A;  3K4F A;  1IRM A;  3HLX A;  1T5P A;  2F2G A;  2GM7 A;  1OTW A;  1P3T A;  3B5O A;  1DVE A;  4NY7 A;  1OZR A;  2RD3 A;  4WD4 A;  1OZE A;  2A2O A;  2DY5 A;  4WMH A;  2ZVU A;  1V8X A;  3TGM A;  3B5P A;  1OYK A;  1XJZ A;  4G7P A;  3RM5 A;  2E7E A;  1N45 A;  3I9T A;  1WNV A;  1Z72 A;  4GPF A;  1SK7 A;  4G98 A;  1WNX A;  3I9U A;  2Z68 A;  3MOO A;  1P3U A;  1TYH A;  4G8P A;  4GPC A;  3HNH A;  3NO6 A;  1N3U A;  4G99 A;  1DVG A;  4GPH A;  4MEC A;  4WWZ A;  1IX3 A;  3HML A;  1IW1 A;  3HOK A;  1OYL A;  1XK2 A;  1VGI A;  1WNW A;  3IBX A;  1S8C A;  1IW0 A;  3BJD A;  1WE1 A;  1P3V A;  1TO9 A;  1IVJ A;  1TWR A;  1WOW A;  1OZW A;  1RCW A;  2A6B A;  1OZL A;  4G8W A; 
#chains in the Genus database with same CATH homology
 1WOX A;  3CZY A;  3I8R A;  1S13 A;  1TO9 B;  1XK3 A;  1ULX A;  1J77 A;  1WZF A;  2A2M A;  4G7T A;  4FN6 A;  2RGZ A;  4WWJ A;  1NI6 A;  2Q4X A;  1J2C A;  1UBB A;  1UDD A;  1YAK A;  4G7U A;  2Q32 A;  3MVU A;  3OQL A;  1RTW A;  4GOH A;  1WZG A;  4G8U A;  4WX0 A;  1OTV A;  2QZC A;  5BTQ A;  2QPP A;  1TWN A;  1J02 A;  2GM8 A;  1IX4 A;  1WZD A;  1YAF A;  2QCX A;  1XK1 A;  1WOV A;  1XK0 A;  4LQX A;  4RAJ A;  3DDE A;  4G7L A;  1WWM A;  3K4F A;  1IRM A;  3HLX A;  1T5P A;  2F2G A;  2GM7 A;  1OTW A;  1P3T A;  3B5O A;  1DVE A;  4NY7 A;  1OZR A;  2RD3 A;  4WD4 A;  1OZE A;  2A2O A;  2DY5 A;  4WMH A;  2ZVU A;  1V8X A;  3TGM A;  3B5P A;  1OYK A;  1XJZ A;  4G7P A;  3RM5 A;  2E7E A;  1N45 A;  3I9T A;  1WNV A;  1Z72 A;  4GPF A;  1SK7 A;  4G98 A;  1WNX A;  3I9U A;  2Z68 A;  3MOO A;  1P3U A;  1TYH A;  4G8P A;  4GPC A;  3HNH A;  3NO6 A;  1N3U A;  4G99 A;  1DVG A;  4GPH A;  4MEC A;  4WWZ A;  1IX3 A;  3HML A;  1IW1 A;  3HOK A;  1OYL A;  1XK2 A;  1VGI A;  1WNW A;  3IBX A;  1S8C A;  1IW0 A;  3BJD A;  1WE1 A;  1P3V A;  1TO9 A;  1IVJ A;  1TWR A;  1WOW A;  1OZW A;  1RCW A;  2A6B A;  1OZL A;  4G8W A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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