4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
1XK1A 2DY5A 2QPPA 1OZEA 4G98A 2E7EA 1P3UA 1XK0A 3I9TA 1J77A 1TWNA 2ZVUA 4FN6A 1WE1A 2QCXA 4G7TA 1WZFA 1J02A 4G7LA 3MOOA 1IX3A 4LQXA 2A6BA 1P3TA 4GPCA 1XK2A 1RTWA 1S13A 3K4FA 4GOHA 1N45A 1J2CA 1WOWA 3MVUA 1OZWA 1V8XA 2Q32A 1TO9A 3B5OA 1NI6A 1IX4A 4GPHA 1TWRA 1XJZA 4WX0A 1OTVA 2A2OA 4G7UA 1YAFA 1OYKA 1ULXA 1DVGA 1YAKA 4WWJA 3IBXA 1RCWA 4G8PA 1TO9B 3B5PA 4G8WA 1XK3A 3OQLA 3DDEA 1N3UA 4G8UA 1OTWA 1P3VA 4WD4A 1SK7A 2A2MA 3HOKA 2RD3A 3HMLA 3BJDA 4WMHA 1WNXA 1WZDA 3CZYA 1WOVA 1OYLA 5BTQA 1OZLA 1DVEA 2QZCA 3TGMA 4NY7A 4MECA 1VGIA 3HNHA 1IVJA 3HLXA 1WOXA 4RAJA 1IW1A 2GM7A 3RM5A 1WZGA 4GPFA 1UBBA 1OZRA 1T5PA 3I9UA 1WNVA 1UDDA 2F2GA 2RGZA 1S8CA 4G99A 4G7PA 4WWZA 2GM8A 3I8RA 1Z72A 1IW0A 2Q4XA 1TYHA 1WWMA 1IRMA 1WNWA 3NO6A 2Z68A
chains in the Genus database with same CATH superfamily
1XK1A 2DY5A 2QPPA 1OZEA 4G98A 2E7EA 1P3UA 1XK0A 3I9TA 1J77A 1TWNA 2ZVUA 4FN6A 1WE1A 2QCXA 4G7TA 1WZFA 1J02A 4G7LA 3MOOA 1IX3A 4LQXA 2A6BA 1P3TA 4GPCA 1XK2A 1RTWA 1S13A 3K4FA 4GOHA 1N45A 1J2CA 1WOWA 3MVUA 1OZWA 1V8XA 2Q32A 1TO9A 3B5OA 1NI6A 1IX4A 4GPHA 1TWRA 1XJZA 4WX0A 1OTVA 2A2OA 4G7UA 1YAFA 1OYKA 1ULXA 1DVGA 1YAKA 4WWJA 3IBXA 1RCWA 4G8PA 1TO9B 3B5PA 4G8WA 1XK3A 3OQLA 3DDEA 1N3UA 4G8UA 1OTWA 1P3VA 4WD4A 2LCUA 1SK7A 2A2MA 3HOKA 2RD3A 3HMLA 3BJDA 4WMHA 1WNXA 1WZDA 3CZYA 1WOVA 1OYLA 5BTQA 1OZLA 1DVEA 2QZCA 3TGMA 4NY7A 4MECA 1VGIA 3HNHA 1IVJA 3HLXA 1WOXA 4RAJA 1IW1A 2GM7A 3RM5A 1WZGA 4GPFA 1UBBA 1OZRA 1T5PA 3I9UA 1WNVA 1UDDA 2F2GA 2RGZA 1S8CA 4G99A 4G7PA 4WWZA 2GM8A 3I8RA 1Z72A 1IW0A 2Q4XA 1TYHA 1WWMA 1IRMA 1WNWA 3NO6A 2Z68A
chains in the Genus database with same CATH topology
1XK1A 2DY5A 2QPPA 1OZEA 4G98A 2E7EA 1P3UA 1XK0A 3I9TA 1J77A 1TWNA 2ZVUA 4FN6A 1WE1A 2QCXA 4G7TA 1WZFA 1J02A 4G7LA 3MOOA 1IX3A 4LQXA 2A6BA 1P3TA 4GPCA 1XK2A 1RTWA 1S13A 3K4FA 4GOHA 1N45A 1J2CA 1WOWA 3MVUA 1OZWA 1V8XA 2Q32A 1TO9A 3B5OA 1NI6A 1IX4A 4GPHA 1TWRA 1XJZA 4WX0A 1OTVA 2A2OA 4G7UA 1YAFA 1OYKA 1ULXA 1DVGA 1YAKA 4WWJA 3IBXA 1RCWA 4G8PA 1TO9B 3B5PA 4G8WA 1XK3A 3OQLA 3DDEA 1N3UA 4G8UA 1OTWA 1P3VA 4WD4A 1SK7A 2A2MA 3HOKA 2RD3A 3HMLA 3BJDA 4WMHA 1WNXA 1WZDA 3CZYA 1WOVA 1OYLA 5BTQA 1OZLA 1DVEA 2QZCA 3TGMA 4NY7A 4MECA 1VGIA 3HNHA 1IVJA 3HLXA 1WOXA 4RAJA 1IW1A 2GM7A 3RM5A 1WZGA 4GPFA 1UBBA 1OZRA 1T5PA 3I9UA 1WNVA 1UDDA 2F2GA 2RGZA 1S8CA 4G99A 4G7PA 4WWZA 2GM8A 3I8RA 1Z72A 1IW0A 2Q4XA 1TYHA 1WWMA 1IRMA 1WNWA 3NO6A 2Z68A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1XK1 A;  2DY5 A;  2QPP A;  1OZE A;  4G98 A;  2E7E A;  1P3U A;  1XK0 A;  3I9T A;  1J77 A;  1TWN A;  2ZVU A;  4FN6 A;  1WE1 A;  2QCX A;  4G7T A;  1WZF A;  1J02 A;  4G7L A;  3MOO A;  1IX3 A;  4LQX A;  2A6B A;  1P3T A;  4GPC A;  1XK2 A;  1RTW A;  1S13 A;  3K4F A;  4GOH A;  1N45 A;  1J2C A;  1WOW A;  3MVU A;  1OZW A;  1V8X A;  2Q32 A;  1TO9 A;  3B5O A;  1NI6 A;  1IX4 A;  4GPH A;  1TWR A;  1XJZ A;  4WX0 A;  1OTV A;  2A2O A;  4G7U A;  1YAF A;  1OYK A;  1ULX A;  1DVG A;  1YAK A;  4WWJ A;  3IBX A;  1RCW A;  4G8P A;  1TO9 B;  3B5P A;  4G8W A;  1XK3 A;  3OQL A;  3DDE A;  1N3U A;  4G8U A;  1OTW A;  1P3V A;  4WD4 A;  1SK7 A;  2A2M A;  3HOK A;  2RD3 A;  3HML A;  3BJD A;  4WMH A;  1WNX A;  1WZD A;  3CZY A;  1WOV A;  1OYL A;  5BTQ A;  1OZL A;  1DVE A;  2QZC A;  3TGM A;  4NY7 A;  4MEC A;  1VGI A;  3HNH A;  1IVJ A;  3HLX A;  1WOX A;  4RAJ A;  1IW1 A;  2GM7 A;  3RM5 A;  1WZG A;  4GPF A;  1UBB A;  1OZR A;  1T5P A;  3I9U A;  1WNV A;  1UDD A;  2F2G A;  2RGZ A;  1S8C A;  4G99 A;  4G7P A;  4WWZ A;  2GM8 A;  3I8R A;  1Z72 A;  1IW0 A;  2Q4X A;  1TYH A;  1WWM A;  1IRM A;  1WNW A;  3NO6 A;  2Z68 A; 
#chains in the Genus database with same CATH topology
 1XK1 A;  2DY5 A;  2QPP A;  1OZE A;  4G98 A;  2E7E A;  1P3U A;  1XK0 A;  3I9T A;  1J77 A;  1TWN A;  2ZVU A;  4FN6 A;  1WE1 A;  2QCX A;  4G7T A;  1WZF A;  1J02 A;  4G7L A;  3MOO A;  1IX3 A;  4LQX A;  2A6B A;  1P3T A;  4GPC A;  1XK2 A;  1RTW A;  1S13 A;  3K4F A;  4GOH A;  1N45 A;  1J2C A;  1WOW A;  3MVU A;  1OZW A;  1V8X A;  2Q32 A;  1TO9 A;  3B5O A;  1NI6 A;  1IX4 A;  4GPH A;  1TWR A;  1XJZ A;  4WX0 A;  1OTV A;  2A2O A;  4G7U A;  1YAF A;  1OYK A;  1ULX A;  1DVG A;  1YAK A;  4WWJ A;  3IBX A;  1RCW A;  4G8P A;  1TO9 B;  3B5P A;  4G8W A;  1XK3 A;  3OQL A;  3DDE A;  1N3U A;  4G8U A;  1OTW A;  1P3V A;  4WD4 A;  2LCU A;  1SK7 A;  2A2M A;  3HOK A;  2RD3 A;  3HML A;  3BJD A;  4WMH A;  1WNX A;  1WZD A;  3CZY A;  1WOV A;  1OYL A;  5BTQ A;  1OZL A;  1DVE A;  2QZC A;  3TGM A;  4NY7 A;  4MEC A;  1VGI A;  3HNH A;  1IVJ A;  3HLX A;  1WOX A;  4RAJ A;  1IW1 A;  2GM7 A;  3RM5 A;  1WZG A;  4GPF A;  1UBB A;  1OZR A;  1T5P A;  3I9U A;  1WNV A;  1UDD A;  2F2G A;  2RGZ A;  1S8C A;  4G99 A;  4G7P A;  4WWZ A;  2GM8 A;  3I8R A;  1Z72 A;  1IW0 A;  2Q4X A;  1TYH A;  1WWM A;  1IRM A;  1WNW A;  3NO6 A;  2Z68 A; 
#chains in the Genus database with same CATH homology
 1XK1 A;  2DY5 A;  2QPP A;  1OZE A;  4G98 A;  2E7E A;  1P3U A;  1XK0 A;  3I9T A;  1J77 A;  1TWN A;  2ZVU A;  4FN6 A;  1WE1 A;  2QCX A;  4G7T A;  1WZF A;  1J02 A;  4G7L A;  3MOO A;  1IX3 A;  4LQX A;  2A6B A;  1P3T A;  4GPC A;  1XK2 A;  1RTW A;  1S13 A;  3K4F A;  4GOH A;  1N45 A;  1J2C A;  1WOW A;  3MVU A;  1OZW A;  1V8X A;  2Q32 A;  1TO9 A;  3B5O A;  1NI6 A;  1IX4 A;  4GPH A;  1TWR A;  1XJZ A;  4WX0 A;  1OTV A;  2A2O A;  4G7U A;  1YAF A;  1OYK A;  1ULX A;  1DVG A;  1YAK A;  4WWJ A;  3IBX A;  1RCW A;  4G8P A;  1TO9 B;  3B5P A;  4G8W A;  1XK3 A;  3OQL A;  3DDE A;  1N3U A;  4G8U A;  1OTW A;  1P3V A;  4WD4 A;  1SK7 A;  2A2M A;  3HOK A;  2RD3 A;  3HML A;  3BJD A;  4WMH A;  1WNX A;  1WZD A;  3CZY A;  1WOV A;  1OYL A;  5BTQ A;  1OZL A;  1DVE A;  2QZC A;  3TGM A;  4NY7 A;  4MEC A;  1VGI A;  3HNH A;  1IVJ A;  3HLX A;  1WOX A;  4RAJ A;  1IW1 A;  2GM7 A;  3RM5 A;  1WZG A;  4GPF A;  1UBB A;  1OZR A;  1T5P A;  3I9U A;  1WNV A;  1UDD A;  2F2G A;  2RGZ A;  1S8C A;  4G99 A;  4G7P A;  4WWZ A;  2GM8 A;  3I8R A;  1Z72 A;  1IW0 A;  2Q4X A;  1TYH A;  1WWM A;  1IRM A;  1WNW A;  3NO6 A;  2Z68 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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