4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
2GM8A 4GPFA 3CZYA 4GOHA 1WNXA 3I9UA 1WZDA 1J2CA 1OTWA 1IX4A 1TYHA 4LQXA 4G8PA 1OTVA 1OZRA 1DVGA 4G98A 1IW1A 1TO9A 1J77A 1WWMA 3B5PA 1UBBA 2QPPA 2RGZA 1XK0A 3K4FA 1XK2A 1IX3A 4G99A 1RTWA 3DDEA 4G7UA 3NO6A 4G8WA 4G7PA 1RCWA 4G7TA 2Q4XA 1YAFA 2GM7A 1XJZA 1P3UA 3OQLA 1TO9B 3I9TA 3IBXA 3TGMA 1OZEA 3HMLA 1SK7A 1UDDA 2A2OA 3I8RA 1WZFA 1J02A 3B5OA 1S8CA 1WOWA 1TWRA 2ZVUA 1WZGA 2QZCA 5BTQA 4GPCA 1WNWA 1P3VA 4NY7A 1IRMA 3HNHA 3HLXA 3MOOA 1T5PA 1OYLA 1S13A 1N45A 4WD4A 1N3UA 2Q32A 1YAKA 1ULXA 3MVUA 1WOXA 2RD3A 1V8XA 1DVEA 4GPHA 3RM5A 4FN6A 2A6BA 4WX0A 3HOKA 4WWJA 2E7EA 3BJDA 4MECA 1P3TA 4WWZA 2Z68A 4RAJA 1OZLA 1Z72A 1IW0A 4WMHA 1WE1A 1WOVA 1TWNA 1XK1A 1XK3A 1OYKA 4G7LA 1NI6A 2A2MA 1WNVA 1OZWA 2DY5A 1IVJA 1VGIA 4G8UA 2F2GA 2QCXA
chains in the Genus database with same CATH superfamily
2GM8A 4GPFA 3CZYA 4GOHA 1WNXA 3I9UA 1WZDA 1J2CA 1OTWA 1IX4A 1TYHA 4LQXA 4G8PA 1OTVA 1OZRA 1DVGA 4G98A 1IW1A 1TO9A 1J77A 2LCUA 1WWMA 3B5PA 1UBBA 2QPPA 2RGZA 1XK0A 3K4FA 1XK2A 1IX3A 4G99A 1RTWA 3DDEA 4G7UA 3NO6A 4G8WA 4G7PA 1RCWA 4G7TA 2Q4XA 1YAFA 2GM7A 1XJZA 1P3UA 3OQLA 1TO9B 3I9TA 3IBXA 3TGMA 1OZEA 3HMLA 1SK7A 1UDDA 2A2OA 3I8RA 1WZFA 1J02A 3B5OA 1S8CA 1WOWA 1TWRA 2ZVUA 1WZGA 2QZCA 5BTQA 4GPCA 1WNWA 1P3VA 4NY7A 1IRMA 3HNHA 3HLXA 3MOOA 1T5PA 1OYLA 1S13A 1N45A 4WD4A 1N3UA 2Q32A 1YAKA 1ULXA 3MVUA 1WOXA 2RD3A 1V8XA 1DVEA 4GPHA 3RM5A 4FN6A 2A6BA 4WX0A 3HOKA 4WWJA 2E7EA 3BJDA 4MECA 1P3TA 4WWZA 2Z68A 4RAJA 1OZLA 1Z72A 1IW0A 4WMHA 1WE1A 1WOVA 1TWNA 1XK1A 1XK3A 1OYKA 4G7LA 1NI6A 2A2MA 1WNVA 1OZWA 2DY5A 1IVJA 1VGIA 4G8UA 2F2GA 2QCXA
chains in the Genus database with same CATH topology
2GM8A 4GPFA 3CZYA 4GOHA 1WNXA 3I9UA 1WZDA 1J2CA 1OTWA 1IX4A 1TYHA 4LQXA 4G8PA 1OTVA 1OZRA 1DVGA 4G98A 1IW1A 1TO9A 1J77A 1WWMA 3B5PA 1UBBA 2QPPA 2RGZA 1XK0A 3K4FA 1XK2A 1IX3A 4G99A 1RTWA 3DDEA 4G7UA 3NO6A 4G8WA 4G7PA 1RCWA 4G7TA 2Q4XA 1YAFA 2GM7A 1XJZA 1P3UA 3OQLA 1TO9B 3I9TA 3IBXA 3TGMA 1OZEA 3HMLA 1SK7A 1UDDA 2A2OA 3I8RA 1WZFA 1J02A 3B5OA 1S8CA 1WOWA 1TWRA 2ZVUA 1WZGA 2QZCA 5BTQA 4GPCA 1WNWA 1P3VA 4NY7A 1IRMA 3HNHA 3HLXA 3MOOA 1T5PA 1OYLA 1S13A 1N45A 4WD4A 1N3UA 2Q32A 1YAKA 1ULXA 3MVUA 1WOXA 2RD3A 1V8XA 1DVEA 4GPHA 3RM5A 4FN6A 2A6BA 4WX0A 3HOKA 4WWJA 2E7EA 3BJDA 4MECA 1P3TA 4WWZA 2Z68A 4RAJA 1OZLA 1Z72A 1IW0A 4WMHA 1WE1A 1WOVA 1TWNA 1XK1A 1XK3A 1OYKA 4G7LA 1NI6A 2A2MA 1WNVA 1OZWA 2DY5A 1IVJA 1VGIA 4G8UA 2F2GA 2QCXA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2GM8 A;  4GPF A;  3CZY A;  4GOH A;  1WNX A;  3I9U A;  1WZD A;  1J2C A;  1OTW A;  1IX4 A;  1TYH A;  4LQX A;  4G8P A;  1OTV A;  1OZR A;  1DVG A;  4G98 A;  1IW1 A;  1TO9 A;  1J77 A;  1WWM A;  3B5P A;  1UBB A;  2QPP A;  2RGZ A;  1XK0 A;  3K4F A;  1XK2 A;  1IX3 A;  4G99 A;  1RTW A;  3DDE A;  4G7U A;  3NO6 A;  4G8W A;  4G7P A;  1RCW A;  4G7T A;  2Q4X A;  1YAF A;  2GM7 A;  1XJZ A;  1P3U A;  3OQL A;  1TO9 B;  3I9T A;  3IBX A;  3TGM A;  1OZE A;  3HML A;  1SK7 A;  1UDD A;  2A2O A;  3I8R A;  1WZF A;  1J02 A;  3B5O A;  1S8C A;  1WOW A;  1TWR A;  2ZVU A;  1WZG A;  2QZC A;  5BTQ A;  4GPC A;  1WNW A;  1P3V A;  4NY7 A;  1IRM A;  3HNH A;  3HLX A;  3MOO A;  1T5P A;  1OYL A;  1S13 A;  1N45 A;  4WD4 A;  1N3U A;  2Q32 A;  1YAK A;  1ULX A;  3MVU A;  1WOX A;  2RD3 A;  1V8X A;  1DVE A;  4GPH A;  3RM5 A;  4FN6 A;  2A6B A;  4WX0 A;  3HOK A;  4WWJ A;  2E7E A;  3BJD A;  4MEC A;  1P3T A;  4WWZ A;  2Z68 A;  4RAJ A;  1OZL A;  1Z72 A;  1IW0 A;  4WMH A;  1WE1 A;  1WOV A;  1TWN A;  1XK1 A;  1XK3 A;  1OYK A;  4G7L A;  1NI6 A;  2A2M A;  1WNV A;  1OZW A;  2DY5 A;  1IVJ A;  1VGI A;  4G8U A;  2F2G A;  2QCX A; 
#chains in the Genus database with same CATH topology
 2GM8 A;  4GPF A;  3CZY A;  4GOH A;  1WNX A;  3I9U A;  1WZD A;  1J2C A;  1OTW A;  1IX4 A;  1TYH A;  4LQX A;  4G8P A;  1OTV A;  1OZR A;  1DVG A;  4G98 A;  1IW1 A;  1TO9 A;  1J77 A;  2LCU A;  1WWM A;  3B5P A;  1UBB A;  2QPP A;  2RGZ A;  1XK0 A;  3K4F A;  1XK2 A;  1IX3 A;  4G99 A;  1RTW A;  3DDE A;  4G7U A;  3NO6 A;  4G8W A;  4G7P A;  1RCW A;  4G7T A;  2Q4X A;  1YAF A;  2GM7 A;  1XJZ A;  1P3U A;  3OQL A;  1TO9 B;  3I9T A;  3IBX A;  3TGM A;  1OZE A;  3HML A;  1SK7 A;  1UDD A;  2A2O A;  3I8R A;  1WZF A;  1J02 A;  3B5O A;  1S8C A;  1WOW A;  1TWR A;  2ZVU A;  1WZG A;  2QZC A;  5BTQ A;  4GPC A;  1WNW A;  1P3V A;  4NY7 A;  1IRM A;  3HNH A;  3HLX A;  3MOO A;  1T5P A;  1OYL A;  1S13 A;  1N45 A;  4WD4 A;  1N3U A;  2Q32 A;  1YAK A;  1ULX A;  3MVU A;  1WOX A;  2RD3 A;  1V8X A;  1DVE A;  4GPH A;  3RM5 A;  4FN6 A;  2A6B A;  4WX0 A;  3HOK A;  4WWJ A;  2E7E A;  3BJD A;  4MEC A;  1P3T A;  4WWZ A;  2Z68 A;  4RAJ A;  1OZL A;  1Z72 A;  1IW0 A;  4WMH A;  1WE1 A;  1WOV A;  1TWN A;  1XK1 A;  1XK3 A;  1OYK A;  4G7L A;  1NI6 A;  2A2M A;  1WNV A;  1OZW A;  2DY5 A;  1IVJ A;  1VGI A;  4G8U A;  2F2G A;  2QCX A; 
#chains in the Genus database with same CATH homology
 2GM8 A;  4GPF A;  3CZY A;  4GOH A;  1WNX A;  3I9U A;  1WZD A;  1J2C A;  1OTW A;  1IX4 A;  1TYH A;  4LQX A;  4G8P A;  1OTV A;  1OZR A;  1DVG A;  4G98 A;  1IW1 A;  1TO9 A;  1J77 A;  1WWM A;  3B5P A;  1UBB A;  2QPP A;  2RGZ A;  1XK0 A;  3K4F A;  1XK2 A;  1IX3 A;  4G99 A;  1RTW A;  3DDE A;  4G7U A;  3NO6 A;  4G8W A;  4G7P A;  1RCW A;  4G7T A;  2Q4X A;  1YAF A;  2GM7 A;  1XJZ A;  1P3U A;  3OQL A;  1TO9 B;  3I9T A;  3IBX A;  3TGM A;  1OZE A;  3HML A;  1SK7 A;  1UDD A;  2A2O A;  3I8R A;  1WZF A;  1J02 A;  3B5O A;  1S8C A;  1WOW A;  1TWR A;  2ZVU A;  1WZG A;  2QZC A;  5BTQ A;  4GPC A;  1WNW A;  1P3V A;  4NY7 A;  1IRM A;  3HNH A;  3HLX A;  3MOO A;  1T5P A;  1OYL A;  1S13 A;  1N45 A;  4WD4 A;  1N3U A;  2Q32 A;  1YAK A;  1ULX A;  3MVU A;  1WOX A;  2RD3 A;  1V8X A;  1DVE A;  4GPH A;  3RM5 A;  4FN6 A;  2A6B A;  4WX0 A;  3HOK A;  4WWJ A;  2E7E A;  3BJD A;  4MEC A;  1P3T A;  4WWZ A;  2Z68 A;  4RAJ A;  1OZL A;  1Z72 A;  1IW0 A;  4WMH A;  1WE1 A;  1WOV A;  1TWN A;  1XK1 A;  1XK3 A;  1OYK A;  4G7L A;  1NI6 A;  2A2M A;  1WNV A;  1OZW A;  2DY5 A;  1IVJ A;  1VGI A;  4G8U A;  2F2G A;  2QCX A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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