4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
molecule keywords Heme oxygenase 1
molecule tags Oxidoreductase
source organism Rattus norvegicus
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
4MECA 4G8PA 3MOOA 1OZEA 2GM7A 1TWRA 1J02A 2A2OA 2QPPA 1UDDA 1WZDA 1IX3A 1WE1A 4RAJA 3HLXA 1RTWA 3IBXA 4G99A 1UBBA 1P3TA 1TYHA 4WD4A 3DDEA 4WMHA 3HMLA 1WOVA 4GOHA 4WWZA 3B5OA 1J2CA 1T5PA 1XJZA 3CZYA 4FN6A 5BTQA 1WNWA 1WNVA 4LQXA 1OZRA 1WZFA 3I9UA 3OQLA 1SK7A 1WWMA 1IRMA 2Q4XA 4NY7A 4G98A 1P3VA 1XK0A 1WZGA 1TO9A 1WNXA 1XK2A 4GPCA 2A6BA 3I8RA 1P3UA 1J77A 1Z72A 1N3UA 1YAFA 1TWNA 4G8UA 2E7EA 3B5PA 2DY5A 1IW1A 3TGMA 1WOWA 1OZWA 1N45A 1OYKA 3BJDA 4G8WA 3RM5A 3K4FA 1OYLA 1TO9B 2GM8A 4G7UA 4WWJA 3I9TA 1S8CA 4WX0A 1IW0A 2QCXA 2QZCA 2Q32A 1VGIA 2F2GA 1ULXA 3HOKA 2RGZA 1OTWA 1IVJA 1IX4A 2Z68A 1NI6A 1V8XA 2ZVUA 1XK3A 1OTVA 1DVEA 1S13A 4G7TA 1RCWA 1XK1A 1DVGA 2A2MA 4G7LA 2RD3A 4GPHA 1YAKA 3NO6A 3HNHA 1WOXA 3MVUA 1OZLA 4GPFA 4G7PA
chains in the Genus database with same CATH superfamily
4MECA 4G8PA 3MOOA 1OZEA 2GM7A 1TWRA 1J02A 2A2OA 2QPPA 1UDDA 1WZDA 1IX3A 1WE1A 4RAJA 3HLXA 1RTWA 3IBXA 4G99A 1UBBA 1P3TA 1TYHA 4WD4A 3DDEA 4WMHA 3HMLA 1WOVA 4GOHA 4WWZA 3B5OA 1J2CA 1T5PA 1XJZA 3CZYA 2LCUA 4FN6A 5BTQA 1WNWA 1WNVA 4LQXA 1OZRA 1WZFA 3I9UA 3OQLA 1SK7A 1WWMA 1IRMA 2Q4XA 4NY7A 4G98A 1P3VA 1XK0A 1WZGA 1TO9A 1WNXA 1XK2A 4GPCA 2A6BA 3I8RA 1P3UA 1J77A 1Z72A 1N3UA 1YAFA 1TWNA 4G8UA 2E7EA 3B5PA 2DY5A 1IW1A 3TGMA 1WOWA 1OZWA 1N45A 1OYKA 3BJDA 4G8WA 3RM5A 3K4FA 1OYLA 1TO9B 2GM8A 4G7UA 4WWJA 3I9TA 1S8CA 4WX0A 1IW0A 2QCXA 2QZCA 2Q32A 1VGIA 2F2GA 1ULXA 3HOKA 2RGZA 1OTWA 1IVJA 1IX4A 2Z68A 1NI6A 1V8XA 2ZVUA 1XK3A 1OTVA 1DVEA 1S13A 4G7TA 1RCWA 1XK1A 1DVGA 2A2MA 4G7LA 2RD3A 4GPHA 1YAKA 3NO6A 3HNHA 1WOXA 3MVUA 1OZLA 4GPFA 4G7PA
chains in the Genus database with same CATH topology
4MECA 4G8PA 3MOOA 1OZEA 2GM7A 1TWRA 1J02A 2A2OA 2QPPA 1UDDA 1WZDA 1IX3A 1WE1A 4RAJA 3HLXA 1RTWA 3IBXA 4G99A 1UBBA 1P3TA 1TYHA 4WD4A 3DDEA 4WMHA 3HMLA 1WOVA 4GOHA 4WWZA 3B5OA 1J2CA 1T5PA 1XJZA 3CZYA 4FN6A 5BTQA 1WNWA 1WNVA 4LQXA 1OZRA 1WZFA 3I9UA 3OQLA 1SK7A 1WWMA 1IRMA 2Q4XA 4NY7A 4G98A 1P3VA 1XK0A 1WZGA 1TO9A 1WNXA 1XK2A 4GPCA 2A6BA 3I8RA 1P3UA 1J77A 1Z72A 1N3UA 1YAFA 1TWNA 4G8UA 2E7EA 3B5PA 2DY5A 1IW1A 3TGMA 1WOWA 1OZWA 1N45A 1OYKA 3BJDA 4G8WA 3RM5A 3K4FA 1OYLA 1TO9B 2GM8A 4G7UA 4WWJA 3I9TA 1S8CA 4WX0A 1IW0A 2QCXA 2QZCA 2Q32A 1VGIA 2F2GA 1ULXA 3HOKA 2RGZA 1OTWA 1IVJA 1IX4A 2Z68A 1NI6A 1V8XA 2ZVUA 1XK3A 1OTVA 1DVEA 1S13A 4G7TA 1RCWA 1XK1A 1DVGA 2A2MA 4G7LA 2RD3A 4GPHA 1YAKA 3NO6A 3HNHA 1WOXA 3MVUA 1OZLA 4GPFA 4G7PA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4MEC A;  4G8P A;  3MOO A;  1OZE A;  2GM7 A;  1TWR A;  1J02 A;  2A2O A;  2QPP A;  1UDD A;  1WZD A;  1IX3 A;  1WE1 A;  4RAJ A;  3HLX A;  1RTW A;  3IBX A;  4G99 A;  1UBB A;  1P3T A;  1TYH A;  4WD4 A;  3DDE A;  4WMH A;  3HML A;  1WOV A;  4GOH A;  4WWZ A;  3B5O A;  1J2C A;  1T5P A;  1XJZ A;  3CZY A;  4FN6 A;  5BTQ A;  1WNW A;  1WNV A;  4LQX A;  1OZR A;  1WZF A;  3I9U A;  3OQL A;  1SK7 A;  1WWM A;  1IRM A;  2Q4X A;  4NY7 A;  4G98 A;  1P3V A;  1XK0 A;  1WZG A;  1TO9 A;  1WNX A;  1XK2 A;  4GPC A;  2A6B A;  3I8R A;  1P3U A;  1J77 A;  1Z72 A;  1N3U A;  1YAF A;  1TWN A;  4G8U A;  2E7E A;  3B5P A;  2DY5 A;  1IW1 A;  3TGM A;  1WOW A;  1OZW A;  1N45 A;  1OYK A;  3BJD A;  4G8W A;  3RM5 A;  3K4F A;  1OYL A;  1TO9 B;  2GM8 A;  4G7U A;  4WWJ A;  3I9T A;  1S8C A;  4WX0 A;  1IW0 A;  2QCX A;  2QZC A;  2Q32 A;  1VGI A;  2F2G A;  1ULX A;  3HOK A;  2RGZ A;  1OTW A;  1IVJ A;  1IX4 A;  2Z68 A;  1NI6 A;  1V8X A;  2ZVU A;  1XK3 A;  1OTV A;  1DVE A;  1S13 A;  4G7T A;  1RCW A;  1XK1 A;  1DVG A;  2A2M A;  4G7L A;  2RD3 A;  4GPH A;  1YAK A;  3NO6 A;  3HNH A;  1WOX A;  3MVU A;  1OZL A;  4GPF A;  4G7P A; 
#chains in the Genus database with same CATH topology
 4MEC A;  4G8P A;  3MOO A;  1OZE A;  2GM7 A;  1TWR A;  1J02 A;  2A2O A;  2QPP A;  1UDD A;  1WZD A;  1IX3 A;  1WE1 A;  4RAJ A;  3HLX A;  1RTW A;  3IBX A;  4G99 A;  1UBB A;  1P3T A;  1TYH A;  4WD4 A;  3DDE A;  4WMH A;  3HML A;  1WOV A;  4GOH A;  4WWZ A;  3B5O A;  1J2C A;  1T5P A;  1XJZ A;  3CZY A;  2LCU A;  4FN6 A;  5BTQ A;  1WNW A;  1WNV A;  4LQX A;  1OZR A;  1WZF A;  3I9U A;  3OQL A;  1SK7 A;  1WWM A;  1IRM A;  2Q4X A;  4NY7 A;  4G98 A;  1P3V A;  1XK0 A;  1WZG A;  1TO9 A;  1WNX A;  1XK2 A;  4GPC A;  2A6B A;  3I8R A;  1P3U A;  1J77 A;  1Z72 A;  1N3U A;  1YAF A;  1TWN A;  4G8U A;  2E7E A;  3B5P A;  2DY5 A;  1IW1 A;  3TGM A;  1WOW A;  1OZW A;  1N45 A;  1OYK A;  3BJD A;  4G8W A;  3RM5 A;  3K4F A;  1OYL A;  1TO9 B;  2GM8 A;  4G7U A;  4WWJ A;  3I9T A;  1S8C A;  4WX0 A;  1IW0 A;  2QCX A;  2QZC A;  2Q32 A;  1VGI A;  2F2G A;  1ULX A;  3HOK A;  2RGZ A;  1OTW A;  1IVJ A;  1IX4 A;  2Z68 A;  1NI6 A;  1V8X A;  2ZVU A;  1XK3 A;  1OTV A;  1DVE A;  1S13 A;  4G7T A;  1RCW A;  1XK1 A;  1DVG A;  2A2M A;  4G7L A;  2RD3 A;  4GPH A;  1YAK A;  3NO6 A;  3HNH A;  1WOX A;  3MVU A;  1OZL A;  4GPF A;  4G7P A; 
#chains in the Genus database with same CATH homology
 4MEC A;  4G8P A;  3MOO A;  1OZE A;  2GM7 A;  1TWR A;  1J02 A;  2A2O A;  2QPP A;  1UDD A;  1WZD A;  1IX3 A;  1WE1 A;  4RAJ A;  3HLX A;  1RTW A;  3IBX A;  4G99 A;  1UBB A;  1P3T A;  1TYH A;  4WD4 A;  3DDE A;  4WMH A;  3HML A;  1WOV A;  4GOH A;  4WWZ A;  3B5O A;  1J2C A;  1T5P A;  1XJZ A;  3CZY A;  4FN6 A;  5BTQ A;  1WNW A;  1WNV A;  4LQX A;  1OZR A;  1WZF A;  3I9U A;  3OQL A;  1SK7 A;  1WWM A;  1IRM A;  2Q4X A;  4NY7 A;  4G98 A;  1P3V A;  1XK0 A;  1WZG A;  1TO9 A;  1WNX A;  1XK2 A;  4GPC A;  2A6B A;  3I8R A;  1P3U A;  1J77 A;  1Z72 A;  1N3U A;  1YAF A;  1TWN A;  4G8U A;  2E7E A;  3B5P A;  2DY5 A;  1IW1 A;  3TGM A;  1WOW A;  1OZW A;  1N45 A;  1OYK A;  3BJD A;  4G8W A;  3RM5 A;  3K4F A;  1OYL A;  1TO9 B;  2GM8 A;  4G7U A;  4WWJ A;  3I9T A;  1S8C A;  4WX0 A;  1IW0 A;  2QCX A;  2QZC A;  2Q32 A;  1VGI A;  2F2G A;  1ULX A;  3HOK A;  2RGZ A;  1OTW A;  1IVJ A;  1IX4 A;  2Z68 A;  1NI6 A;  1V8X A;  2ZVU A;  1XK3 A;  1OTV A;  1DVE A;  1S13 A;  4G7T A;  1RCW A;  1XK1 A;  1DVG A;  2A2M A;  4G7L A;  2RD3 A;  4GPH A;  1YAK A;  3NO6 A;  3HNH A;  1WOX A;  3MVU A;  1OZL A;  4GPF A;  4G7P A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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