4G8PA

Rat heme oxygenase-1 in complex with heme and co with 16 hr illumination: laser on
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Rattus norvegicus
molecule keywords Heme oxygenase 1
total genus 90
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g8pA00
2F2GA 4WWJA 4G7PA 2Q4XA 1WOWA 3DDEA 3MVUA 1OZEA 4G7LA 1OYKA 3CZYA 3B5OA 1RTWA 4G8UA 1OTWA 1V8XA 4G98A 1IW1A 4G8PA 1OZLA 1P3VA 2A2OA 2A2MA 3I8RA 4MECA 1OZRA 4GPFA 1UBBA 1XK0A 1ULXA 3HLXA 1P3TA 1DVEA 2Z68A 1IX4A 1WOXA 1VGIA 2Q32A 3HNHA 4WMHA 1N45A 2A6BA 3BJDA 1OTVA 4LQXA 1IX3A 1OYLA 2RGZA 4WWZA 4GPHA 1YAFA 2QPPA 1T5PA 3K4FA 2ZVUA 1XK1A 1S13A 1TWNA 2GM8A 5BTQA 1IRMA 3IBXA 2DY5A 4G7TA 4WD4A 3B5PA 3HMLA 1J02A 3HOKA 3RM5A 2RD3A 1TO9B 3I9UA 3NO6A 1WOVA 1RCWA 1WE1A 4NY7A 3I9TA 1NI6A 3OQLA 1WZDA 2GM7A 4GPCA 1WNXA 2E7EA 1OZWA 1P3UA 1YAKA 1J2CA 1WZGA 1XK2A 2QCXA 1N3UA 4WX0A 1WZFA 1XK3A 4GOHA 3TGMA 1IVJA 1WNVA 1WWMA 1DVGA 1XJZA 1TO9A 1J77A 1IW0A 1TYHA 1S8CA 4G99A 1Z72A 2QZCA 1UDDA 1WNWA 4G7UA 3MOOA 1TWRA 1SK7A 4FN6A 4RAJA 4G8WA
chains in the Genus database with same CATH superfamily
2F2GA 4WWJA 4G7PA 2Q4XA 1WOWA 3DDEA 3MVUA 1OZEA 4G7LA 1OYKA 3CZYA 3B5OA 1RTWA 4G8UA 1OTWA 1V8XA 4G98A 1IW1A 4G8PA 1OZLA 1P3VA 2A2OA 2A2MA 3I8RA 4MECA 1OZRA 4GPFA 1UBBA 1XK0A 1ULXA 3HLXA 1P3TA 1DVEA 2Z68A 1IX4A 1WOXA 1VGIA 2Q32A 3HNHA 4WMHA 1N45A 2A6BA 3BJDA 1OTVA 4LQXA 1IX3A 1OYLA 2RGZA 4WWZA 4GPHA 1YAFA 2QPPA 1T5PA 3K4FA 2ZVUA 1XK1A 1S13A 1TWNA 2GM8A 5BTQA 1IRMA 3IBXA 2DY5A 4G7TA 4WD4A 3B5PA 3HMLA 1J02A 3HOKA 3RM5A 2RD3A 1TO9B 3I9UA 3NO6A 1WOVA 1RCWA 1WE1A 4NY7A 3I9TA 1NI6A 3OQLA 1WZDA 2GM7A 4GPCA 1WNXA 2E7EA 1OZWA 1P3UA 1YAKA 1J2CA 1WZGA 2LCUA 1XK2A 2QCXA 1N3UA 4WX0A 1WZFA 1XK3A 4GOHA 3TGMA 1IVJA 1WNVA 1WWMA 1DVGA 1XJZA 1TO9A 1J77A 1IW0A 1TYHA 1S8CA 4G99A 1Z72A 2QZCA 1UDDA 1WNWA 4G7UA 3MOOA 1TWRA 1SK7A 4FN6A 4RAJA 4G8WA
chains in the Genus database with same CATH topology
2F2GA 4WWJA 4G7PA 2Q4XA 1WOWA 3DDEA 3MVUA 1OZEA 4G7LA 1OYKA 3CZYA 3B5OA 1RTWA 4G8UA 1OTWA 1V8XA 4G98A 1IW1A 4G8PA 1OZLA 1P3VA 2A2OA 2A2MA 3I8RA 4MECA 1OZRA 4GPFA 1UBBA 1XK0A 1ULXA 3HLXA 1P3TA 1DVEA 2Z68A 1IX4A 1WOXA 1VGIA 2Q32A 3HNHA 4WMHA 1N45A 2A6BA 3BJDA 1OTVA 4LQXA 1IX3A 1OYLA 2RGZA 4WWZA 4GPHA 1YAFA 2QPPA 1T5PA 3K4FA 2ZVUA 1XK1A 1S13A 1TWNA 2GM8A 5BTQA 1IRMA 3IBXA 2DY5A 4G7TA 4WD4A 3B5PA 3HMLA 1J02A 3HOKA 3RM5A 2RD3A 1TO9B 3I9UA 3NO6A 1WOVA 1RCWA 1WE1A 4NY7A 3I9TA 1NI6A 3OQLA 1WZDA 2GM7A 4GPCA 1WNXA 2E7EA 1OZWA 1P3UA 1YAKA 1J2CA 1WZGA 1XK2A 2QCXA 1N3UA 4WX0A 1WZFA 1XK3A 4GOHA 3TGMA 1IVJA 1WNVA 1WWMA 1DVGA 1XJZA 1TO9A 1J77A 1IW0A 1TYHA 1S8CA 4G99A 1Z72A 2QZCA 1UDDA 1WNWA 4G7UA 3MOOA 1TWRA 1SK7A 4FN6A 4RAJA 4G8WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F2G A;  4WWJ A;  4G7P A;  2Q4X A;  1WOW A;  3DDE A;  3MVU A;  1OZE A;  4G7L A;  1OYK A;  3CZY A;  3B5O A;  1RTW A;  4G8U A;  1OTW A;  1V8X A;  4G98 A;  1IW1 A;  4G8P A;  1OZL A;  1P3V A;  2A2O A;  2A2M A;  3I8R A;  4MEC A;  1OZR A;  4GPF A;  1UBB A;  1XK0 A;  1ULX A;  3HLX A;  1P3T A;  1DVE A;  2Z68 A;  1IX4 A;  1WOX A;  1VGI A;  2Q32 A;  3HNH A;  4WMH A;  1N45 A;  2A6B A;  3BJD A;  1OTV A;  4LQX A;  1IX3 A;  1OYL A;  2RGZ A;  4WWZ A;  4GPH A;  1YAF A;  2QPP A;  1T5P A;  3K4F A;  2ZVU A;  1XK1 A;  1S13 A;  1TWN A;  2GM8 A;  5BTQ A;  1IRM A;  3IBX A;  2DY5 A;  4G7T A;  4WD4 A;  3B5P A;  3HML A;  1J02 A;  3HOK A;  3RM5 A;  2RD3 A;  1TO9 B;  3I9U A;  3NO6 A;  1WOV A;  1RCW A;  1WE1 A;  4NY7 A;  3I9T A;  1NI6 A;  3OQL A;  1WZD A;  2GM7 A;  4GPC A;  1WNX A;  2E7E A;  1OZW A;  1P3U A;  1YAK A;  1J2C A;  1WZG A;  1XK2 A;  2QCX A;  1N3U A;  4WX0 A;  1WZF A;  1XK3 A;  4GOH A;  3TGM A;  1IVJ A;  1WNV A;  1WWM A;  1DVG A;  1XJZ A;  1TO9 A;  1J77 A;  1IW0 A;  1TYH A;  1S8C A;  4G99 A;  1Z72 A;  2QZC A;  1UDD A;  1WNW A;  4G7U A;  3MOO A;  1TWR A;  1SK7 A;  4FN6 A;  4RAJ A;  4G8W A; 
#chains in the Genus database with same CATH topology
 2F2G A;  4WWJ A;  4G7P A;  2Q4X A;  1WOW A;  3DDE A;  3MVU A;  1OZE A;  4G7L A;  1OYK A;  3CZY A;  3B5O A;  1RTW A;  4G8U A;  1OTW A;  1V8X A;  4G98 A;  1IW1 A;  4G8P A;  1OZL A;  1P3V A;  2A2O A;  2A2M A;  3I8R A;  4MEC A;  1OZR A;  4GPF A;  1UBB A;  1XK0 A;  1ULX A;  3HLX A;  1P3T A;  1DVE A;  2Z68 A;  1IX4 A;  1WOX A;  1VGI A;  2Q32 A;  3HNH A;  4WMH A;  1N45 A;  2A6B A;  3BJD A;  1OTV A;  4LQX A;  1IX3 A;  1OYL A;  2RGZ A;  4WWZ A;  4GPH A;  1YAF A;  2QPP A;  1T5P A;  3K4F A;  2ZVU A;  1XK1 A;  1S13 A;  1TWN A;  2GM8 A;  5BTQ A;  1IRM A;  3IBX A;  2DY5 A;  4G7T A;  4WD4 A;  3B5P A;  3HML A;  1J02 A;  3HOK A;  3RM5 A;  2RD3 A;  1TO9 B;  3I9U A;  3NO6 A;  1WOV A;  1RCW A;  1WE1 A;  4NY7 A;  3I9T A;  1NI6 A;  3OQL A;  1WZD A;  2GM7 A;  4GPC A;  1WNX A;  2E7E A;  1OZW A;  1P3U A;  1YAK A;  1J2C A;  1WZG A;  2LCU A;  1XK2 A;  2QCX A;  1N3U A;  4WX0 A;  1WZF A;  1XK3 A;  4GOH A;  3TGM A;  1IVJ A;  1WNV A;  1WWM A;  1DVG A;  1XJZ A;  1TO9 A;  1J77 A;  1IW0 A;  1TYH A;  1S8C A;  4G99 A;  1Z72 A;  2QZC A;  1UDD A;  1WNW A;  4G7U A;  3MOO A;  1TWR A;  1SK7 A;  4FN6 A;  4RAJ A;  4G8W A; 
#chains in the Genus database with same CATH homology
 2F2G A;  4WWJ A;  4G7P A;  2Q4X A;  1WOW A;  3DDE A;  3MVU A;  1OZE A;  4G7L A;  1OYK A;  3CZY A;  3B5O A;  1RTW A;  4G8U A;  1OTW A;  1V8X A;  4G98 A;  1IW1 A;  4G8P A;  1OZL A;  1P3V A;  2A2O A;  2A2M A;  3I8R A;  4MEC A;  1OZR A;  4GPF A;  1UBB A;  1XK0 A;  1ULX A;  3HLX A;  1P3T A;  1DVE A;  2Z68 A;  1IX4 A;  1WOX A;  1VGI A;  2Q32 A;  3HNH A;  4WMH A;  1N45 A;  2A6B A;  3BJD A;  1OTV A;  4LQX A;  1IX3 A;  1OYL A;  2RGZ A;  4WWZ A;  4GPH A;  1YAF A;  2QPP A;  1T5P A;  3K4F A;  2ZVU A;  1XK1 A;  1S13 A;  1TWN A;  2GM8 A;  5BTQ A;  1IRM A;  3IBX A;  2DY5 A;  4G7T A;  4WD4 A;  3B5P A;  3HML A;  1J02 A;  3HOK A;  3RM5 A;  2RD3 A;  1TO9 B;  3I9U A;  3NO6 A;  1WOV A;  1RCW A;  1WE1 A;  4NY7 A;  3I9T A;  1NI6 A;  3OQL A;  1WZD A;  2GM7 A;  4GPC A;  1WNX A;  2E7E A;  1OZW A;  1P3U A;  1YAK A;  1J2C A;  1WZG A;  1XK2 A;  2QCX A;  1N3U A;  4WX0 A;  1WZF A;  1XK3 A;  4GOH A;  3TGM A;  1IVJ A;  1WNV A;  1WWM A;  1DVG A;  1XJZ A;  1TO9 A;  1J77 A;  1IW0 A;  1TYH A;  1S8C A;  4G99 A;  1Z72 A;  2QZC A;  1UDD A;  1WNW A;  4G7U A;  3MOO A;  1TWR A;  1SK7 A;  4FN6 A;  4RAJ A;  4G8W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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