5DO9B

Structure of regulator of g protein signaling 8 (rgs8) in complex with alf4-activated galpha-q
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
134
structure length
134
Chain Sequence
SMLKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Regulator of G Protein Signaling 8 (RGS8)-G alpha q Complex: MOLECULAR BASIS FOR G alpha SELECTIVITY.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
total genus 55
structure length 134
sequence length 134
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 5do9B02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 5do9B01
1CMZA 5HE2A 5DO9B 3PVWA 3C7KB 3UZTA 1EZYA 2OWIA 2JNUA 3C7LA 4PNKA 3CIKA 3KRWA 1FQKB 1DK8A 1OMWA 3V5WA 1AGRE 1EZTA 1FQIA 2DLVA 2CRPA 2EBZA 2IK8B 4EKDB 2BCJA 5HE3A 1FQJB 4TNBA 5HE0A 5HE1A 3PVUA 3PSCA 2BT2A 1EMUA 2ODEB 4MK0A 2AF0A 3KRXA 3NYOA 4TNDA 2GTPC 2IHBB 2V4ZB 2BV1A 2D9JA 2IHDA 2OJ4A 3NYNA 2JM5A
chains in the Genus database with same CATH superfamily
1CMZA 5HE2A 5DO9B 3PVWA 3C7KB 4HTEA 3UZTA 2OWIA 2JNUA 1EZYA 3C7LA 4PNKA 3CIKA 3KRWA 3QYFA 1FQKB 1DK8A 5REQB 1OMWA 3V5WA 1AGRE 1EZTA 1FQIA 2DLVA 2CRPA 2EBZA 2IK8B 4EKDB 2BCJA 5HE3A 1FQJB 4TNBA 5HE0A 5HE1A 3PVUA 3PSCA 2BT2A 1EMUA 2ODEB 4MK0A 2AF0A 3KRXA 3NYOA 3I5QA 4TNDA 2GTPC 2IHBB 2V4ZB 2BV1A 2D9JA 2IHDA 2OJ4A 3NYNA 2JM5A
chains in the Genus database with same CATH topology
1CMZA 5HE2A 5DO9B 3PVWA 3C7KB 3UZTA 1EZYA 2OWIA 2JNUA 3C7LA 4PNKA 3CIKA 3KRWA 3QYFA 1FQKB 1DK8A 5REQB 1OMWA 3V5WA 1AGRE 1EZTA 1FQIA 2DLVA 2CRPA 2EBZA 2IK8B 4EKDB 2BCJA 5HE3A 1FQJB 4TNBA 5HE0A 5HE1A 3PVUA 3PSCA 2BT2A 1EMUA 2ODEB 4MK0A 2AF0A 3KRXA 3NYOA 4TNDA 2GTPC 2IHBB 2V4ZB 2BV1A 2D9JA 2IHDA 2OJ4A 3NYNA 2JM5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CMZ A;  5HE2 A;  5DO9 B;  3PVW A;  3C7K B;  3UZT A;  1EZY A;  2OWI A;  2JNU A;  3C7L A;  4PNK A;  3CIK A;  3KRW A;  1FQK B;  1DK8 A;  1OMW A;  3V5W A;  1AGR E;  1EZT A;  1FQI A;  2DLV A;  2CRP A;  2EBZ A;  2IK8 B;  4EKD B;  2BCJ A;  5HE3 A;  1FQJ B;  4TNB A;  5HE0 A;  5HE1 A;  3PVU A;  3PSC A;  2BT2 A;  1EMU A;  2ODE B;  4MK0 A;  2AF0 A;  3KRX A;  3NYO A;  4TND A;  2GTP C;  2IHB B;  2V4Z B;  2BV1 A;  2D9J A;  2IHD A;  2OJ4 A;  3NYN A;  2JM5 A; 
#chains in the Genus database with same CATH topology
 1CMZ A;  5HE2 A;  5DO9 B;  3PVW A;  3C7K B;  4HTE A;  3UZT A;  2OWI A;  2JNU A;  1EZY A;  3C7L A;  4PNK A;  3CIK A;  3KRW A;  3QYF A;  1FQK B;  1DK8 A;  5REQ B;  1OMW A;  3V5W A;  1AGR E;  1EZT A;  1FQI A;  2DLV A;  2CRP A;  2EBZ A;  2IK8 B;  4EKD B;  2BCJ A;  5HE3 A;  1FQJ B;  4TNB A;  5HE0 A;  5HE1 A;  3PVU A;  3PSC A;  2BT2 A;  1EMU A;  2ODE B;  4MK0 A;  2AF0 A;  3KRX A;  3NYO A;  3I5Q A;  4TND A;  2GTP C;  2IHB B;  2V4Z B;  2BV1 A;  2D9J A;  2IHD A;  2OJ4 A;  3NYN A;  2JM5 A; 
#chains in the Genus database with same CATH homology
 1CMZ A;  5HE2 A;  5DO9 B;  3PVW A;  3C7K B;  3UZT A;  1EZY A;  2OWI A;  2JNU A;  3C7L A;  4PNK A;  3CIK A;  3KRW A;  3QYF A;  1FQK B;  1DK8 A;  5REQ B;  1OMW A;  3V5W A;  1AGR E;  1EZT A;  1FQI A;  2DLV A;  2CRP A;  2EBZ A;  2IK8 B;  4EKD B;  2BCJ A;  5HE3 A;  1FQJ B;  4TNB A;  5HE0 A;  5HE1 A;  3PVU A;  3PSC A;  2BT2 A;  1EMU A;  2ODE B;  4MK0 A;  2AF0 A;  3KRX A;  3NYO A;  4TND A;  2GTP C;  2IHB B;  2V4Z B;  2BV1 A;  2D9J A;  2IHD A;  2OJ4 A;  3NYN A;  2JM5 A; 
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similar chains in the Genus database (?% sequence similarity)
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