5DO9B

Structure of regulator of g protein signaling 8 (rgs8) in complex with alf4-activated galpha-q
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
134
structure length
134
Chain Sequence
SMLKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Regulator of G Protein Signaling 8 (RGS8)-G alpha q Complex: MOLECULAR BASIS FOR G alpha SELECTIVITY.
pubmed doi rcsb
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
molecule tags Protein binding
source organism Mus musculus
total genus 55
structure length 134
sequence length 134
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 5do9B02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 5do9B01
2D9JA 3KRXA 1OMWA 2DLVA 5DO9B 2BT2A 5HE3A 1FQJB 2BV1A 2OWIA 2IHBB 1EZYA 2IK8B 3PSCA 2JM5A 4TNDA 1AGRE 4TNBA 4PNKA 3CIKA 2IHDA 2V4ZB 3KRWA 5HE0A 1FQIA 3PVUA 3PVWA 3C7LA 4EKDB 3UZTA 1DK8A 2AF0A 3NYNA 4MK0A 5HE2A 2OJ4A 1FQKB 1EZTA 3V5WA 2JNUA 3C7KB 2GTPC 2CRPA 1CMZA 2EBZA 3NYOA 1EMUA 5HE1A 2ODEB 2BCJA
chains in the Genus database with same CATH superfamily
2D9JA 3KRXA 1OMWA 2DLVA 5DO9B 2BT2A 5HE3A 1FQJB 2BV1A 2OWIA 2IHBB 1EZYA 2IK8B 3PSCA 2JM5A 4TNDA 1AGRE 4TNBA 4PNKA 3CIKA 2IHDA 2V4ZB 3KRWA 5HE0A 1FQIA 3PVUA 3PVWA 3C7LA 4EKDB 3UZTA 5REQB 1DK8A 2AF0A 3NYNA 4MK0A 5HE2A 2OJ4A 1FQKB 3I5QA 1EZTA 3V5WA 3QYFA 2JNUA 3C7KB 2GTPC 2CRPA 4HTEA 1CMZA 2EBZA 3NYOA 1EMUA 5HE1A 2ODEB 2BCJA
chains in the Genus database with same CATH topology
2D9JA 3KRXA 1OMWA 2DLVA 5DO9B 2BT2A 5HE3A 1FQJB 2BV1A 2OWIA 2IHBB 1EZYA 2IK8B 3PSCA 2JM5A 4TNDA 1AGRE 4TNBA 4PNKA 3CIKA 2IHDA 2V4ZB 3KRWA 5HE0A 1FQIA 3PVUA 3PVWA 3C7LA 4EKDB 3UZTA 5REQB 1DK8A 2AF0A 3NYNA 4MK0A 5HE2A 2OJ4A 1FQKB 1EZTA 3V5WA 3QYFA 2JNUA 3C7KB 2GTPC 2CRPA 1CMZA 2EBZA 3NYOA 1EMUA 5HE1A 2ODEB 2BCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D9J A;  3KRX A;  1OMW A;  2DLV A;  5DO9 B;  2BT2 A;  5HE3 A;  1FQJ B;  2BV1 A;  2OWI A;  2IHB B;  1EZY A;  2IK8 B;  3PSC A;  2JM5 A;  4TND A;  1AGR E;  4TNB A;  4PNK A;  3CIK A;  2IHD A;  2V4Z B;  3KRW A;  5HE0 A;  1FQI A;  3PVU A;  3PVW A;  3C7L A;  4EKD B;  3UZT A;  1DK8 A;  2AF0 A;  3NYN A;  4MK0 A;  5HE2 A;  2OJ4 A;  1FQK B;  1EZT A;  3V5W A;  2JNU A;  3C7K B;  2GTP C;  2CRP A;  1CMZ A;  2EBZ A;  3NYO A;  1EMU A;  5HE1 A;  2ODE B;  2BCJ A; 
#chains in the Genus database with same CATH topology
 2D9J A;  3KRX A;  1OMW A;  2DLV A;  5DO9 B;  2BT2 A;  5HE3 A;  1FQJ B;  2BV1 A;  2OWI A;  2IHB B;  1EZY A;  2IK8 B;  3PSC A;  2JM5 A;  4TND A;  1AGR E;  4TNB A;  4PNK A;  3CIK A;  2IHD A;  2V4Z B;  3KRW A;  5HE0 A;  1FQI A;  3PVU A;  3PVW A;  3C7L A;  4EKD B;  3UZT A;  5REQ B;  1DK8 A;  2AF0 A;  3NYN A;  4MK0 A;  5HE2 A;  2OJ4 A;  1FQK B;  3I5Q A;  1EZT A;  3V5W A;  3QYF A;  2JNU A;  3C7K B;  2GTP C;  2CRP A;  4HTE A;  1CMZ A;  2EBZ A;  3NYO A;  1EMU A;  5HE1 A;  2ODE B;  2BCJ A; 
#chains in the Genus database with same CATH homology
 2D9J A;  3KRX A;  1OMW A;  2DLV A;  5DO9 B;  2BT2 A;  5HE3 A;  1FQJ B;  2BV1 A;  2OWI A;  2IHB B;  1EZY A;  2IK8 B;  3PSC A;  2JM5 A;  4TND A;  1AGR E;  4TNB A;  4PNK A;  3CIK A;  2IHD A;  2V4Z B;  3KRW A;  5HE0 A;  1FQI A;  3PVU A;  3PVW A;  3C7L A;  4EKD B;  3UZT A;  5REQ B;  1DK8 A;  2AF0 A;  3NYN A;  4MK0 A;  5HE2 A;  2OJ4 A;  1FQK B;  1EZT A;  3V5W A;  3QYF A;  2JNU A;  3C7K B;  2GTP C;  2CRP A;  1CMZ A;  2EBZ A;  3NYO A;  1EMU A;  5HE1 A;  2ODE B;  2BCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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