1TKUA

Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of candida albicans in complex with ribulose-5-phosphate
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
202
structure length
196
Chain Sequence
NIFTPIEEALEAYKNGEFLIVMDDEDRENEGDLIMAAELITQEKMAFLVRYSSGYVCVPLSEERANQLELPPMLAGTAYTITCDFAEGTTTGISAHDRALTTRSLANPNSKPQDFIKPGHILPLRAVPGLLKKRRGHTEAAVQLSTLAGLQPAGVICELVRDEDGLMMRLDDCIQFGKKHGIKIININQLVEYISK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
pubmed doi rcsb
molecule tags Isomerase
source organism Candida albicans
molecule keywords 3,4-Dihydroxy-2-butanone 4-phosphate Synthase
total genus 64
structure length 196
sequence length 202
chains with identical sequence B
ec nomenclature ec 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 1tkuA00
3H07A 3LS6A 1KK9A 1PVYA 1TKSA 4P77A 1TKUA 1K4PA 1IEZA 1K4IA 1HRUA 2RISA 4P6DA 1SNNA 4P8JA 1G57A 2MX1A 1JCUA 4I14A 2EQAA 4P6CA 1K4LA 4E1BA 3LRJA 1G58A 3LQUA 3MGZA 1K49A 4P8EA 3MIOA 4P6PA 1K4OA 3AJEA 4FFJA 3MK5A 1K7JA 1PVWA 2RIUA 3L7VA
chains in the Genus database with same CATH superfamily
3H07A 3VTIA 3LS6A 1KK9A 1PVYA 1TKSA 3VEZA 4P77A 3VEXA 1TKUA 1K4PA 3VESA 3VEOA 3VF2A 1IEZA 1K4IA 1HRUA 2RISA 4P6DA 1SNNA 4P8JA 3VTHA 1G57A 2MX1A 3TSQA 1JCUA 3TTDA 4I14A 2EQAA 3VF4A 4P6CA 1K4LA 3TSUA 3TTCA 3LRJA 3VERA 4E1BA 1G58A 3LQUA 3VENA 3MGZA 1K49A 4P8EA 3VETA 3VEWA 3TSPA 3MIOA 4P6PA 1K4OA 3AJEA 4FFJA 3TTFA 3MK5A 1K7JA 1PVWA 2RIUA 3L7VA
chains in the Genus database with same CATH topology
3H07A 3VTIA 3LS6A 1KK9A 1PVYA 1TKSA 3VEZA 4P77A 3VEXA 1TKUA 1K4PA 3VESA 3VEOA 3VF2A 1IEZA 1K4IA 1HRUA 2RISA 4P6DA 1SNNA 4P8JA 3VTHA 1G57A 2MX1A 3TSQA 1JCUA 3TTDA 4I14A 2EQAA 3VF4A 4P6CA 1K4LA 3TSUA 3TTCA 3LRJA 3VERA 4E1BA 1G58A 3LQUA 3VENA 3MGZA 1K49A 4P8EA 3VETA 3VEWA 3TSPA 3MIOA 4P6PA 1K4OA 3AJEA 4FFJA 3TTFA 3MK5A 1K7JA 1PVWA 2RIUA 3L7VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H07 A;  3LS6 A;  1KK9 A;  1PVY A;  1TKS A;  4P77 A;  1TKU A;  1K4P A;  1IEZ A;  1K4I A;  1HRU A;  2RIS A;  4P6D A;  1SNN A;  4P8J A;  1G57 A;  2MX1 A;  1JCU A;  4I14 A;  2EQA A;  4P6C A;  1K4L A;  4E1B A;  3LRJ A;  1G58 A;  3LQU A;  3MGZ A;  1K49 A;  4P8E A;  3MIO A;  4P6P A;  1K4O A;  3AJE A;  4FFJ A;  3MK5 A;  1K7J A;  1PVW A;  2RIU A;  3L7V A; 
#chains in the Genus database with same CATH topology
 3H07 A;  3VTI A;  3LS6 A;  1KK9 A;  1PVY A;  1TKS A;  3VEZ A;  4P77 A;  3VEX A;  1TKU A;  1K4P A;  3VES A;  3VEO A;  3VF2 A;  1IEZ A;  1K4I A;  1HRU A;  2RIS A;  4P6D A;  1SNN A;  4P8J A;  3VTH A;  1G57 A;  2MX1 A;  3TSQ A;  1JCU A;  3TTD A;  4I14 A;  2EQA A;  3VF4 A;  4P6C A;  1K4L A;  3TSU A;  3TTC A;  3LRJ A;  3VER A;  4E1B A;  1G58 A;  3LQU A;  3VEN A;  3MGZ A;  1K49 A;  4P8E A;  3VET A;  3VEW A;  3TSP A;  3MIO A;  4P6P A;  1K4O A;  3AJE A;  4FFJ A;  3TTF A;  3MK5 A;  1K7J A;  1PVW A;  2RIU A;  3L7V A; 
#chains in the Genus database with same CATH homology
 3H07 A;  3VTI A;  3LS6 A;  1KK9 A;  1PVY A;  1TKS A;  3VEZ A;  4P77 A;  3VEX A;  1TKU A;  1K4P A;  3VES A;  3VEO A;  3VF2 A;  1IEZ A;  1K4I A;  1HRU A;  2RIS A;  4P6D A;  1SNN A;  4P8J A;  3VTH A;  1G57 A;  2MX1 A;  3TSQ A;  1JCU A;  3TTD A;  4I14 A;  2EQA A;  3VF4 A;  4P6C A;  1K4L A;  3TSU A;  3TTC A;  3LRJ A;  3VER A;  4E1B A;  1G58 A;  3LQU A;  3VEN A;  3MGZ A;  1K49 A;  4P8E A;  3VET A;  3VEW A;  3TSP A;  3MIO A;  4P6P A;  1K4O A;  3AJE A;  4FFJ A;  3TTF A;  3MK5 A;  1K7J A;  1PVW A;  2RIU A;  3L7V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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