3MGZA

Crystal structure of dhbps domain of bi-functional dhbps/gtp cyclohydrolase ii from mycobacterium tuberculosis at ph 4.0
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
206
structure length
186
Chain Sequence
MTRLDSVERAVADIAAGKAVIVIDDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 60
structure length 186
sequence length 206
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mgzA00
4FFJA 1G58A 1K4LA 4P6PA 1KK9A 3L7VA 3LS6A 1IEZA 3MK5A 4P77A 1K49A 1G57A 1K7JA 3LQUA 1PVYA 4P6DA 2EQAA 3MGZA 1K4IA 2RIUA 4P6CA 1PVWA 1SNNA 1HRUA 1TKSA 4E1BA 1TKUA 3MIOA 1K4PA 4P8EA 3AJEA 1JCUA 4P8JA 3H07A 3LRJA 2MX1A 4I14A 2RISA 1K4OA
chains in the Genus database with same CATH superfamily
4FFJA 1G58A 3VF4A 3TTCA 1K4LA 4P6PA 1KK9A 3L7VA 3LS6A 1IEZA 3MK5A 4P77A 3TSUA 1K49A 3VF2A 3VENA 3TSQA 1G57A 3VEZA 3TSPA 1K7JA 3VTHA 3LQUA 1PVYA 4P6DA 2EQAA 3MGZA 1K4IA 2RIUA 4P6CA 1PVWA 3TTDA 1SNNA 1HRUA 1TKSA 3VEWA 4E1BA 3VEXA 1TKUA 3MIOA 3VETA 1K4PA 3VESA 4P8EA 3AJEA 1JCUA 4P8JA 3VERA 3VTIA 3H07A 3TTFA 3LRJA 2MX1A 4I14A 2RISA 1K4OA 3VEOA
chains in the Genus database with same CATH topology
4FFJA 1G58A 3VF4A 3TTCA 1K4LA 4P6PA 1KK9A 3L7VA 3LS6A 1IEZA 3MK5A 4P77A 3TSUA 1K49A 3VF2A 3VENA 3TSQA 1G57A 3VEZA 3TSPA 1K7JA 3VTHA 3LQUA 1PVYA 4P6DA 2EQAA 3MGZA 1K4IA 2RIUA 4P6CA 1PVWA 3TTDA 1SNNA 1HRUA 1TKSA 3VEWA 4E1BA 3VEXA 1TKUA 3MIOA 3VETA 1K4PA 3VESA 4P8EA 3AJEA 1JCUA 4P8JA 3VERA 3VTIA 3H07A 3TTFA 3LRJA 2MX1A 4I14A 2RISA 1K4OA 3VEOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FFJ A;  1G58 A;  1K4L A;  4P6P A;  1KK9 A;  3L7V A;  3LS6 A;  1IEZ A;  3MK5 A;  4P77 A;  1K49 A;  1G57 A;  1K7J A;  3LQU A;  1PVY A;  4P6D A;  2EQA A;  3MGZ A;  1K4I A;  2RIU A;  4P6C A;  1PVW A;  1SNN A;  1HRU A;  1TKS A;  4E1B A;  1TKU A;  3MIO A;  1K4P A;  4P8E A;  3AJE A;  1JCU A;  4P8J A;  3H07 A;  3LRJ A;  2MX1 A;  4I14 A;  2RIS A;  1K4O A; 
#chains in the Genus database with same CATH topology
 4FFJ A;  1G58 A;  3VF4 A;  3TTC A;  1K4L A;  4P6P A;  1KK9 A;  3L7V A;  3LS6 A;  1IEZ A;  3MK5 A;  4P77 A;  3TSU A;  1K49 A;  3VF2 A;  3VEN A;  3TSQ A;  1G57 A;  3VEZ A;  3TSP A;  1K7J A;  3VTH A;  3LQU A;  1PVY A;  4P6D A;  2EQA A;  3MGZ A;  1K4I A;  2RIU A;  4P6C A;  1PVW A;  3TTD A;  1SNN A;  1HRU A;  1TKS A;  3VEW A;  4E1B A;  3VEX A;  1TKU A;  3MIO A;  3VET A;  1K4P A;  3VES A;  4P8E A;  3AJE A;  1JCU A;  4P8J A;  3VER A;  3VTI A;  3H07 A;  3TTF A;  3LRJ A;  2MX1 A;  4I14 A;  2RIS A;  1K4O A;  3VEO A; 
#chains in the Genus database with same CATH homology
 4FFJ A;  1G58 A;  3VF4 A;  3TTC A;  1K4L A;  4P6P A;  1KK9 A;  3L7V A;  3LS6 A;  1IEZ A;  3MK5 A;  4P77 A;  3TSU A;  1K49 A;  3VF2 A;  3VEN A;  3TSQ A;  1G57 A;  3VEZ A;  3TSP A;  1K7J A;  3VTH A;  3LQU A;  1PVY A;  4P6D A;  2EQA A;  3MGZ A;  1K4I A;  2RIU A;  4P6C A;  1PVW A;  3TTD A;  1SNN A;  1HRU A;  1TKS A;  3VEW A;  4E1B A;  3VEX A;  1TKU A;  3MIO A;  3VET A;  1K4P A;  3VES A;  4P8E A;  3AJE A;  1JCU A;  4P8J A;  3VER A;  3VTI A;  3H07 A;  3TTF A;  3LRJ A;  2MX1 A;  4I14 A;  2RIS A;  1K4O A;  3VEO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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