1IEZA

Solution structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis
Total Genus 30
20406080100120140160180200051015202530
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
217
structure length
217
Chain Sequence
MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
2040608010012014016018020020015010050
051015202530Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS6 (198-201)AH7 (202-213)S1 (29-32)TIV5 (41-44)TI3 (46-49)AH2 (52-61)S4 (176-177)TIV7 (86-89)TIV8 (87-90)TIV9 (90-93)TIV14 (129-132)TI4 (101-104)TIV10 (102-105)TI5 (127-130)AH4 (111-122)TIV11 (107-110)TIV12 (124-127)TI6 (146-149)TII1 (143-146)AH5 (154-163)TIV15 (144-147)TIV17 (177-180)AH6 (185-196)O2 (167-169)S2 (67-70)S3 (138-141)AH3 (72-78)AH1 (13-25)Updating...
connected with : NaN
molecule tags Isomerase
source organism Escherichia coli
publication title The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site.
pubmed doi rcsb
molecule keywords 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase
total genus 30
structure length 217
sequence length 217
ec nomenclature ec 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
pdb deposition date 2001-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 1iezA00
1K7JA 4P8EA 3LS6A 1PVYA 1K49A 3AJEA 4P77A 2EQAA 2RIUA 1G57A 3H07A 1TKSA 4FFJA 1HRUA 3MK5A 1TKUA 3LRJA 4P6DA 3MGZA 1PVWA 4P6CA 1K4IA 4P6PA 1G58A 1SNNA 4E1BA 1IEZA 3LQUA 2MX1A 4P8JA 1JCUA 1KK9A 1K4LA 3MIOA 3L7VA 1K4PA 4I14A 2RISA 1K4OA
chains in the Genus database with same CATH superfamily
1K7JA 4P8EA 3TTFA 3VEZA 3LS6A 3VTIA 1PVYA 3VEXA 1K49A 3AJEA 3VERA 4P77A 3VESA 2EQAA 2RIUA 1G57A 3H07A 1TKSA 4FFJA 1HRUA 3MK5A 3VENA 1TKUA 3LRJA 4P6DA 3MGZA 3TTDA 3VTHA 1PVWA 4P6CA 1K4IA 4P6PA 3TSUA 3VF2A 1G58A 1SNNA 3VEWA 3VF4A 4E1BA 1IEZA 3LQUA 3VEOA 2MX1A 4P8JA 1JCUA 1KK9A 1K4LA 3TSQA 3MIOA 3TSPA 3L7VA 1K4PA 4I14A 2RISA 3VETA 1K4OA 3TTCA
chains in the Genus database with same CATH topology
1K7JA 4P8EA 3TTFA 3VEZA 3LS6A 3VTIA 1PVYA 3VEXA 1K49A 3AJEA 3VERA 4P77A 3VESA 2EQAA 2RIUA 1G57A 3H07A 1TKSA 4FFJA 1HRUA 3MK5A 3VENA 1TKUA 3LRJA 4P6DA 3MGZA 3TTDA 3VTHA 1PVWA 4P6CA 1K4IA 4P6PA 3TSUA 3VF2A 1G58A 1SNNA 3VEWA 3VF4A 4E1BA 1IEZA 3LQUA 3VEOA 2MX1A 4P8JA 1JCUA 1KK9A 1K4LA 3TSQA 3MIOA 3TSPA 3L7VA 1K4PA 4I14A 2RISA 3VETA 1K4OA 3TTCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K7J A;  4P8E A;  3LS6 A;  1PVY A;  1K49 A;  3AJE A;  4P77 A;  2EQA A;  2RIU A;  1G57 A;  3H07 A;  1TKS A;  4FFJ A;  1HRU A;  3MK5 A;  1TKU A;  3LRJ A;  4P6D A;  3MGZ A;  1PVW A;  4P6C A;  1K4I A;  4P6P A;  1G58 A;  1SNN A;  4E1B A;  1IEZ A;  3LQU A;  2MX1 A;  4P8J A;  1JCU A;  1KK9 A;  1K4L A;  3MIO A;  3L7V A;  1K4P A;  4I14 A;  2RIS A;  1K4O A; 
#chains in the Genus database with same CATH topology
 1K7J A;  4P8E A;  3TTF A;  3VEZ A;  3LS6 A;  3VTI A;  1PVY A;  3VEX A;  1K49 A;  3AJE A;  3VER A;  4P77 A;  3VES A;  2EQA A;  2RIU A;  1G57 A;  3H07 A;  1TKS A;  4FFJ A;  1HRU A;  3MK5 A;  3VEN A;  1TKU A;  3LRJ A;  4P6D A;  3MGZ A;  3TTD A;  3VTH A;  1PVW A;  4P6C A;  1K4I A;  4P6P A;  3TSU A;  3VF2 A;  1G58 A;  1SNN A;  3VEW A;  3VF4 A;  4E1B A;  1IEZ A;  3LQU A;  3VEO A;  2MX1 A;  4P8J A;  1JCU A;  1KK9 A;  1K4L A;  3TSQ A;  3MIO A;  3TSP A;  3L7V A;  1K4P A;  4I14 A;  2RIS A;  3VET A;  1K4O A;  3TTC A; 
#chains in the Genus database with same CATH homology
 1K7J A;  4P8E A;  3TTF A;  3VEZ A;  3LS6 A;  3VTI A;  1PVY A;  3VEX A;  1K49 A;  3AJE A;  3VER A;  4P77 A;  3VES A;  2EQA A;  2RIU A;  1G57 A;  3H07 A;  1TKS A;  4FFJ A;  1HRU A;  3MK5 A;  3VEN A;  1TKU A;  3LRJ A;  4P6D A;  3MGZ A;  3TTD A;  3VTH A;  1PVW A;  4P6C A;  1K4I A;  4P6P A;  3TSU A;  3VF2 A;  1G58 A;  1SNN A;  3VEW A;  3VF4 A;  4E1B A;  1IEZ A;  3LQU A;  3VEO A;  2MX1 A;  4P8J A;  1JCU A;  1KK9 A;  1K4L A;  3TSQ A;  3MIO A;  3TSP A;  3L7V A;  1K4P A;  4I14 A;  2RIS A;  3VET A;  1K4O A;  3TTC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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