3EP3A

Human adometdc d174n mutant with no putrescine bound
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
260
structure length
242
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFSQPNQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 59
structure length 242
sequence length 260
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 3ep3A00
3EPBA 3EP4A 1MHMA 3EP5A 2IIIA 1I7BA 3DZ2A 1TMIA 3H0WA 1I72A 3EPAA 3EP9A 3EP7A 1JENA 3DZ5A 1I7MA 3DZ6A 3DZ3A 3EP3A 1I79A 3H0VA 3DZ7A 3EP8A 1I7CA 3EP6A 1VR7A 1JL0A 3DZ4A 1MSVA 1TLUA 5TVOA
chains in the Genus database with same CATH superfamily
3EPBA 3EP4A 1MHMA 3EP5A 2IIIA 1I7BA 3DZ2A 1TMIA 3H0WA 1I72A 3EPAA 3EP9A 3EP7A 1JENA 3DZ5A 1I7MA 3DZ6A 3DZ3A 3EP3A 1I79A 3H0VA 3DZ7A 3EP8A 1I7CA 3EP6A 1VR7A 1JL0A 3DZ4A 1MSVA 1TLUA 5TVOA
chains in the Genus database with same CATH topology
3EPBA 3DZ6B 3EP4A 3DZ3B 1MHMA 3EP3B 1I79B 3H0VB 3DZ7B 3EP5A 2IIIA 3EP8B 1I7CB 3EP6B 1I7BA 3DZ4B 3DZ2A 1TMIA 3H0WA 1I72A 3EPAA 5TVOB 3EP9A 3EPBB 3EP7A 1JENA 3DZ5A 3EP4B 1MHMB 3EP5B 1I7MA 3DZ6A 1I7BB 3DZ3A 3DZ2B 3EP3A 1I79A 3H0VA 3DZ7A 3H0WB 3EPAB 3EP9B 1I7CA 3EP6A 1I72B 1VR7A 1JL0A 3DZ4A 3EP7B 3EP8A 1MSVA 1JENB 3DZ5B 1TLUA 5TVOA 1I7MB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EPB A;  3EP4 A;  1MHM A;  3EP5 A;  2III A;  1I7B A;  3DZ2 A;  1TMI A;  3H0W A;  1I72 A;  3EPA A;  3EP9 A;  3EP7 A;  1JEN A;  3DZ5 A;  1I7M A;  3DZ6 A;  3DZ3 A;  3EP3 A;  1I79 A;  3H0V A;  3DZ7 A;  3EP8 A;  1I7C A;  3EP6 A;  1VR7 A;  1JL0 A;  3DZ4 A;  1MSV A;  1TLU A;  5TVO A; 
#chains in the Genus database with same CATH topology
 3EPB A;  3EP4 A;  1MHM A;  3EP5 A;  2III A;  1I7B A;  3DZ2 A;  1TMI A;  3H0W A;  1I72 A;  3EPA A;  3EP9 A;  3EP7 A;  1JEN A;  3DZ5 A;  1I7M A;  3DZ6 A;  3DZ3 A;  3EP3 A;  1I79 A;  3H0V A;  3DZ7 A;  3EP8 A;  1I7C A;  3EP6 A;  1VR7 A;  1JL0 A;  3DZ4 A;  1MSV A;  1TLU A;  5TVO A; 
#chains in the Genus database with same CATH homology
 3EPB A;  3DZ6 B;  3EP4 A;  3DZ3 B;  1MHM A;  3EP3 B;  1I79 B;  3H0V B;  3DZ7 B;  3EP5 A;  2III A;  3EP8 B;  1I7C B;  3EP6 B;  1I7B A;  3DZ4 B;  3DZ2 A;  1TMI A;  3H0W A;  1I72 A;  3EPA A;  5TVO B;  3EP9 A;  3EPB B;  3EP7 A;  1JEN A;  3DZ5 A;  3EP4 B;  1MHM B;  3EP5 B;  1I7M A;  3DZ6 A;  1I7B B;  3DZ3 A;  3DZ2 B;  3EP3 A;  1I79 A;  3H0V A;  3DZ7 A;  3H0W B;  3EPA B;  3EP9 B;  1I7C A;  3EP6 A;  1I72 B;  1VR7 A;  1JL0 A;  3DZ4 A;  3EP7 B;  3EP8 A;  1MSV A;  1JEN B;  3DZ5 B;  1TLU A;  5TVO A;  1I7M B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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