3EP3A

Human adometdc d174n mutant with no putrescine bound
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
260
structure length
242
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFSQPNQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 59
structure length 242
sequence length 260
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 3ep3A00
1I7MA 5TVOA 1TLUA 1I7CA 1I7BA 3DZ6A 3EP7A 3EP9A 1JENA 1I79A 3DZ5A 3H0WA 3EP3A 1VR7A 3EPBA 2IIIA 3DZ4A 3DZ3A 3DZ2A 3EPAA 1MHMA 3DZ7A 1JL0A 3EP6A 3EP8A 3EP5A 1I72A 1TMIA 3EP4A 1MSVA 3H0VA
chains in the Genus database with same CATH superfamily
1I7MA 5TVOA 1TLUA 1I7CA 1I7BA 3DZ6A 3EP7A 3EP9A 1JENA 1I79A 3DZ5A 3H0WA 3EP3A 1VR7A 3EPBA 2IIIA 3DZ4A 3DZ3A 3DZ2A 3EPAA 1MHMA 3DZ7A 1JL0A 3EP6A 3EP8A 3EP5A 1I72A 1TMIA 3EP4A 1MSVA 3H0VA
chains in the Genus database with same CATH topology
1I7MB 1I7MA 5TVOA 1TLUA 1I7CB 1I7BB 1I7CA 3DZ6B 1I7BA 3EP7B 3DZ6A 3EP7A 3EP9B 1I79B 3DZ5B 3H0WB 1JENB 1JENA 3EP9A 1I79A 3DZ5A 3H0WA 3EPBB 3EP3B 3EP3A 1VR7A 3EPBA 2IIIA 3DZ3B 3DZ4B 3DZ2B 3EPAB 1MHMB 3DZ7B 3DZ3A 3DZ4A 3DZ2A 3EPAA 1MHMA 1JL0A 3DZ7A 3EP6B 3EP8B 3EP5B 1I72B 3EP6A 3EP4B 3EP8A 3EP5A 1I72A 1TMIA 3EP4A 3H0VB 1MSVA 5TVOB 3H0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I7M A;  5TVO A;  1TLU A;  1I7C A;  1I7B A;  3DZ6 A;  3EP7 A;  3EP9 A;  1JEN A;  1I79 A;  3DZ5 A;  3H0W A;  3EP3 A;  1VR7 A;  3EPB A;  2III A;  3DZ4 A;  3DZ3 A;  3DZ2 A;  3EPA A;  1MHM A;  3DZ7 A;  1JL0 A;  3EP6 A;  3EP8 A;  3EP5 A;  1I72 A;  1TMI A;  3EP4 A;  1MSV A;  3H0V A; 
#chains in the Genus database with same CATH topology
 1I7M A;  5TVO A;  1TLU A;  1I7C A;  1I7B A;  3DZ6 A;  3EP7 A;  3EP9 A;  1JEN A;  1I79 A;  3DZ5 A;  3H0W A;  3EP3 A;  1VR7 A;  3EPB A;  2III A;  3DZ4 A;  3DZ3 A;  3DZ2 A;  3EPA A;  1MHM A;  3DZ7 A;  1JL0 A;  3EP6 A;  3EP8 A;  3EP5 A;  1I72 A;  1TMI A;  3EP4 A;  1MSV A;  3H0V A; 
#chains in the Genus database with same CATH homology
 1I7M B;  1I7M A;  5TVO A;  1TLU A;  1I7C B;  1I7B B;  1I7C A;  3DZ6 B;  1I7B A;  3EP7 B;  3DZ6 A;  3EP7 A;  3EP9 B;  1I79 B;  3DZ5 B;  3H0W B;  1JEN B;  1JEN A;  3EP9 A;  1I79 A;  3DZ5 A;  3H0W A;  3EPB B;  3EP3 B;  3EP3 A;  1VR7 A;  3EPB A;  2III A;  3DZ3 B;  3DZ4 B;  3DZ2 B;  3EPA B;  1MHM B;  3DZ7 B;  3DZ3 A;  3DZ4 A;  3DZ2 A;  3EPA A;  1MHM A;  1JL0 A;  3DZ7 A;  3EP6 B;  3EP8 B;  3EP5 B;  1I72 B;  3EP6 A;  3EP4 B;  3EP8 A;  3EP5 A;  1I72 A;  1TMI A;  3EP4 A;  3H0V B;  1MSV A;  5TVO B;  3H0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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