3EP5B

Human adometdc e178q mutant with no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
57
Chain Sequence
HFFEGTEKLLEVWFSRQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 57
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep5B01
1I7MB 3DZ3B 3H0WB 3DZ2B 3EP4B 3DZ7B 3EP7B 3EP9B 3EP3B 3EP5B 1MHMB 3DZ6B 3DZ5B 1I72B 1I7BB 1JENB 3H0VB 1I7CB 3EP8B 1I79B 3DZ4B 5TVOB 3EPBB 3EP6B 3EPAB
chains in the Genus database with same CATH superfamily
4R51A 5KVSA 3PYXA 1GPDG 1VC2A 3EP5B 3IWBB 1TA4A 3OA2A 1YL6A 3TW3A 4R3NA 1I32A 3KUXA 4IQ8A 4MVJI 3ZJXA 4GMGA 3PZRA 1DSSG 3MTJA 3OHSX 3C8MA 3DZ3B 5M6DA 3EP4B 1P1HA 1P1KA 1J0XO 3DB2A 3HJAA 2VYVA 1H6BA 1JENB 1I7BB 2NVWA 1E5LA 4XQGA 1JKFA 2XF8A 2DC1A 3O9ZA 5C7OO 5JW6A 2FPNA 1E77A 3UW3A 3EC7A 4MVJD 3KV3O 3LC1O 1DC5A 3NT4A 3B20A 1GAEO 2PKQO 1NWHA 1RM5A 3DZ6B 2R00A 2Q22A 1UYJA 4MVJG 1GR0A 2IXAA 3CEAA 5T73A 2YV3A 3GDOA 4F3YA 5EERA 1QMIA 1EBUA 3EPBB 3MZ0A 3U3XA 4JN6B 2GYYA 1LC0A 4N54A 1H6CA 4QX6A 2D2IA 4MJLA 2X0NA 4MVJA 4DPKA 2IXBA 4PLPA 1T4DA 3EP8B 1E7YA 3GPDG 3KSZO 3BIOA 3HNPA 3WGOA 1CF2O 4INAA 4LGVA 3V2UA 3WGYA 3IDSA 4Z0HO 4R5MA 3OQBA 2POQX 3LC2O 4GPD1 1OZAA 2HKIA 3IWDB 1FF9A 3DBVO 1TVEA 3HQ4O 4EW6A 1H94A 3I23A 1HDGO 4YWJA 2I3GA 1PQUA 3RC1A 1YDWA 3WYBA 1GD1O 2GLXA 4O8JA 3KGDA 3E1KA 1U8FO 3WGQA 3E9MA 3RC7A 1EBFA 3GFGA 4O89A 4R41A 1B7GO 4K9DA 1I72B 3QVTA 4WNCA 1VM6A 2CZCA 5C7LO 2X5KO 2GZ1A 5AQ1A 1NVMB 1OFGA 4AK1A 4XB1A 1U1IA 1ARZA 3V1YA 1T4BA 4R5HA 4PG6A 1JKIA 1Q7GA 3MOIA 3WYCA 3QY9A 3INGA 3NTRA 3F4LA 1E5QA 2H63A 1DPGA 5EINA 1DRUA 5KVQA 4KOAA 3K73O 1P9LA 4XR4A 3NTOA 5JY6A 1Q2XA 3Q2IA 4ZICA 3BTSA 4DPLA 1H6DA 3Q0EA 2R00C 3Q2KA 4MVJF 5JYFA 3EP6B 4LSMA 3PWSA 4PG5A 4WOJA 3WGZA 3VAZA 1GADO 3DMTA 4XQCA 2NQTA 3HSKA 4DIBA 3ZDFA 4MKZA 4XB2A 3H0VB 4XQEA 2DBVO 1RM0A 5EIOA 3FD8A 2AXQA 2CVOA 3DZ4B 4HKTA 2HJSA 1YL5A 2GZ3A 5TVOB 3NTQA 1CERA 4R54A 2O4UX 5A02A 1PU2A 1IHYA 3TV1A 3PYMA 3DZ2B 3WBFA 3JSAA 3PZBA 5JYEA 1LA2A 3B1JA 1VKOA 4TVBA 4O59O 2PH5A 3E6AA 2B4RO 5JYAA 5C7IO 4MIOA 3GNQA 1NX6A 5J9GA 1P1IA 1H9AA 4II7A 5AVOA 3E5RA 3CINA 1VSVA 3QVWA 5A05A 3ZCXA 3HXLA 3E18A 4O63O 1YS4A 3DO5A 3EVNA 1NPTO 2P2SA 3CIFA 1TB4A 4NHEA 1NBOA 1E7MA 1ZNQO 1QMHA 3H9EO 1MB4A 2DUUA 3PFWO 3WBBA 3Q1LA 4GMFA 2EP5A 3H0WB 3NT5A 3K2BA 3IWCB 4WNIA 2EP7A 5CEFA 2Q49A 3PQVA 1DIHA 3DR3A 3OA0A 2YYYA 2BHLA 3L4SO 1DC3A 1F06A 2G17A 1XYGA 1DBVO 1I7CB 3M2TA 2I5PO 3FHLA 2DPGA 2DAPA 1SZJG 4XRGA 3QW2A 4MIEA 1J5PA 2G82A 1H2HA 3QV1A 1NQAO 3RVDA 4P8RA 4PG7A 3E82A 3QVXA 3RC9A 1MHMB 1ML3A 4R3WA 3CPSA 4HADA 4RL6A 1DC6A 3DMTC 1NQOA 1P1FA 2PKRA 1GYQA 3TUXA 1K3TA 3CMCO 4R4JA 3RCBA 1CRWG 3EPAB 4DBVO 1OBFO 4MVJP 1QXSA 1RYDA 1IHXA 5A03A 2EJWA 4L8VA 1PS8A 1XEAA 5BNTA 5GZ6A 3DOCA 1H93A 2VYND 3RC2A 1RYEA 2GZ2A 1JN0A 1H6AA 3L6OO 2Q4EA 4IQ0A 3EZYA 1YL7A 1H9BA 1ZH8A 4CLQA 3BTVA 1I33A 4PG8A 3TZ6A 4BOYA 3L0DA 3STHA 1DC4A 3EP7B 3IJPA 3PWKA 4MINA 3EP9B 4L9RA 4ZHSA 2BH9A 4LRTB 1PQPA 3Q11A 1A7KA 3VOSA 1BRMA 4MVJH 5A04A 1GL3A 3BTUA 2VYNA 3DTYA 5DDIP 4MVJE 1LC3A 1MC4A 1GCUA 3NT2A 2PKQP 5GZ3A 4XQ9A 5EESA 4DPMA 3EP3B 1VKNA 3UUWA 1C3VA 3IP3A 4MIYA 3WB9A 3KSDO 3PYLA 5A06A 3B1KA 3TUTA 4YDRA 3K9QO 1P1JA 2B4TO 2I3AA 2OZPA 1DAPA 1PR3A 3RBVA 1I7MB 1NQ5A 1TLTA 5GZ1A 3DZ7B 4FB5A 1DRWA 4GQAA 2QZ9A 4LRSB 4MKXA 3DZ5B 1QKIA 1EVJA 3DAPA 3LVFO 1NWCA 3EUWA 2O48X 2X5JO 3ABIA 3C1AA 3V5NA 1DRVA 1S7CA 1I79B 1GYPA 1YWGO 1RM3A 4PG4A 3QVSA 2GD1O 1RM4A 4H3VA 4MVJM 3LC7O 1VSUA 2VYVD 2HO5A
chains in the Genus database with same CATH topology
1I7MB 2IIIA 1I7MA 3DZ3B 3H0WA 3H0WB 3DZ2A 1TLUA 3DZ7A 3DZ2B 3EP4A 3EP4B 3DZ7B 3EP7B 3EP7A 3EP3A 3EP9B 3EP3B 3EP9A 1MHMA 3EP5B 3EP5A 1MHMB 3DZ5A 3DZ6B 1I72A 1I7BA 3DZ6A 3DZ5B 1I72B 1JENB 1I7BB 1JENA 3H0VB 3H0VA 1TMIA 1MSVA 1I7CB 1I7CA 1I79A 3EP8B 1I79B 3EP8A 1VR7A 1JL0A 3DZ4B 3DZ4A 5TVOB 3EPBB 5TVOA 3EPBA 3EP6B 3EPAB 3EP6A 3EPAA 3DZ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I7M B;  3DZ3 B;  3H0W B;  3DZ2 B;  3EP4 B;  3DZ7 B;  3EP7 B;  3EP9 B;  3EP3 B;  3EP5 B;  1MHM B;  3DZ6 B;  3DZ5 B;  1I72 B;  1I7B B;  1JEN B;  3H0V B;  1I7C B;  3EP8 B;  1I79 B;  3DZ4 B;  5TVO B;  3EPB B;  3EP6 B;  3EPA B; 
#chains in the Genus database with same CATH topology
 4R51 A;  5KVS A;  3PYX A;  1GPD G;  1VC2 A;  3EP5 B;  3IWB B;  1TA4 A;  3OA2 A;  1YL6 A;  3TW3 A;  4R3N A;  1I32 A;  3KUX A;  4IQ8 A;  4MVJ I;  3ZJX A;  4GMG A;  3PZR A;  1DSS G;  3MTJ A;  3OHS X;  3C8M A;  3DZ3 B;  5M6D A;  3EP4 B;  1P1H A;  1P1K A;  1J0X O;  3DB2 A;  3HJA A;  2VYV A;  1H6B A;  1JEN B;  1I7B B;  2NVW A;  1E5L A;  4XQG A;  1JKF A;  2XF8 A;  2DC1 A;  3O9Z A;  5C7O O;  5JW6 A;  2FPN A;  1E77 A;  3UW3 A;  3EC7 A;  4MVJ D;  3KV3 O;  3LC1 O;  1DC5 A;  3NT4 A;  3B20 A;  1GAE O;  2PKQ O;  1NWH A;  1RM5 A;  3DZ6 B;  2R00 A;  2Q22 A;  1UYJ A;  4MVJ G;  1GR0 A;  2IXA A;  3CEA A;  5T73 A;  2YV3 A;  3GDO A;  4F3Y A;  5EER A;  1QMI A;  1EBU A;  3EPB B;  3MZ0 A;  3U3X A;  4JN6 B;  2GYY A;  1LC0 A;  4N54 A;  1H6C A;  4QX6 A;  2D2I A;  4MJL A;  2X0N A;  4MVJ A;  4DPK A;  2IXB A;  4PLP A;  1T4D A;  3EP8 B;  1E7Y A;  3GPD G;  3KSZ O;  3BIO A;  3HNP A;  3WGO A;  1CF2 O;  4INA A;  4LGV A;  3V2U A;  3WGY A;  3IDS A;  4Z0H O;  4R5M A;  3OQB A;  2POQ X;  3LC2 O;  4GPD 1;  1OZA A;  2HKI A;  3IWD B;  1FF9 A;  3DBV O;  1TVE A;  3HQ4 O;  4EW6 A;  1H94 A;  3I23 A;  1HDG O;  4YWJ A;  2I3G A;  1PQU A;  3RC1 A;  1YDW A;  3WYB A;  1GD1 O;  2GLX A;  4O8J A;  3KGD A;  3E1K A;  1U8F O;  3WGQ A;  3E9M A;  3RC7 A;  1EBF A;  3GFG A;  4O89 A;  4R41 A;  1B7G O;  4K9D A;  1I72 B;  3QVT A;  4WNC A;  1VM6 A;  2CZC A;  5C7L O;  2X5K O;  2GZ1 A;  5AQ1 A;  1NVM B;  1OFG A;  4AK1 A;  4XB1 A;  1U1I A;  1ARZ A;  3V1Y A;  1T4B A;  4R5H A;  4PG6 A;  1JKI A;  1Q7G A;  3MOI A;  3WYC A;  3QY9 A;  3ING A;  3NTR A;  3F4L A;  1E5Q A;  2H63 A;  1DPG A;  5EIN A;  1DRU A;  5KVQ A;  4KOA A;  3K73 O;  1P9L A;  4XR4 A;  3NTO A;  5JY6 A;  1Q2X A;  3Q2I A;  4ZIC A;  3BTS A;  4DPL A;  1H6D A;  3Q0E A;  2R00 C;  3Q2K A;  4MVJ F;  5JYF A;  3EP6 B;  4LSM A;  3PWS A;  4PG5 A;  4WOJ A;  3WGZ A;  3VAZ A;  1GAD O;  3DMT A;  4XQC A;  2NQT A;  3HSK A;  4DIB A;  3ZDF A;  4MKZ A;  4XB2 A;  3H0V B;  4XQE A;  2DBV O;  1RM0 A;  5EIO A;  3FD8 A;  2AXQ A;  2CVO A;  3DZ4 B;  4HKT A;  2HJS A;  1YL5 A;  2GZ3 A;  5TVO B;  3NTQ A;  1CER A;  4R54 A;  2O4U X;  5A02 A;  1PU2 A;  1IHY A;  3TV1 A;  3PYM A;  3DZ2 B;  3WBF A;  3JSA A;  3PZB A;  5JYE A;  1LA2 A;  3B1J A;  1VKO A;  4TVB A;  4O59 O;  2PH5 A;  3E6A A;  2B4R O;  5JYA A;  5C7I O;  4MIO A;  3GNQ A;  1NX6 A;  5J9G A;  1P1I A;  1H9A A;  4II7 A;  5AVO A;  3E5R A;  3CIN A;  1VSV A;  3QVW A;  5A05 A;  3ZCX A;  3HXL A;  3E18 A;  4O63 O;  1YS4 A;  3DO5 A;  3EVN A;  1NPT O;  2P2S A;  3CIF A;  1TB4 A;  4NHE A;  1NBO A;  1E7M A;  1ZNQ O;  1QMH A;  3H9E O;  1MB4 A;  2DUU A;  3PFW O;  3WBB A;  3Q1L A;  4GMF A;  2EP5 A;  3H0W B;  3NT5 A;  3K2B A;  3IWC B;  4WNI A;  2EP7 A;  5CEF A;  2Q49 A;  3PQV A;  1DIH A;  3DR3 A;  3OA0 A;  2YYY A;  2BHL A;  3L4S O;  1DC3 A;  1F06 A;  2G17 A;  1XYG A;  1DBV O;  1I7C B;  3M2T A;  2I5P O;  3FHL A;  2DPG A;  2DAP A;  1SZJ G;  4XRG A;  3QW2 A;  4MIE A;  1J5P A;  2G82 A;  1H2H A;  3QV1 A;  1NQA O;  3RVD A;  4P8R A;  4PG7 A;  3E82 A;  3QVX A;  3RC9 A;  1MHM B;  1ML3 A;  4R3W A;  3CPS A;  4HAD A;  4RL6 A;  1DC6 A;  3DMT C;  1NQO A;  1P1F A;  2PKR A;  1GYQ A;  3TUX A;  1K3T A;  3CMC O;  4R4J A;  3RCB A;  1CRW G;  3EPA B;  4DBV O;  1OBF O;  4MVJ P;  1QXS A;  1RYD A;  1IHX A;  5A03 A;  2EJW A;  4L8V A;  1PS8 A;  1XEA A;  5BNT A;  5GZ6 A;  3DOC A;  1H93 A;  2VYN D;  3RC2 A;  1RYE A;  2GZ2 A;  1JN0 A;  1H6A A;  3L6O O;  2Q4E A;  4IQ0 A;  3EZY A;  1YL7 A;  1H9B A;  1ZH8 A;  4CLQ A;  3BTV A;  1I33 A;  4PG8 A;  3TZ6 A;  4BOY A;  3L0D A;  3STH A;  1DC4 A;  3EP7 B;  3IJP A;  3PWK A;  4MIN A;  3EP9 B;  4L9R A;  4ZHS A;  2BH9 A;  4LRT B;  1PQP A;  3Q11 A;  1A7K A;  3VOS A;  1BRM A;  4MVJ H;  5A04 A;  1GL3 A;  3BTU A;  2VYN A;  3DTY A;  5DDI P;  4MVJ E;  1LC3 A;  1MC4 A;  1GCU A;  3NT2 A;  2PKQ P;  5GZ3 A;  4XQ9 A;  5EES A;  4DPM A;  3EP3 B;  1VKN A;  3UUW A;  1C3V A;  3IP3 A;  4MIY A;  3WB9 A;  3KSD O;  3PYL A;  5A06 A;  3B1K A;  3TUT A;  4YDR A;  3K9Q O;  1P1J A;  2B4T O;  2I3A A;  2OZP A;  1DAP A;  1PR3 A;  3RBV A;  1I7M B;  1NQ5 A;  1TLT A;  5GZ1 A;  3DZ7 B;  4FB5 A;  1DRW A;  4GQA A;  2QZ9 A;  4LRS B;  4MKX A;  3DZ5 B;  1QKI A;  1EVJ A;  3DAP A;  3LVF O;  1NWC A;  3EUW A;  2O48 X;  2X5J O;  3ABI A;  3C1A A;  3V5N A;  1DRV A;  1S7C A;  1I79 B;  1GYP A;  1YWG O;  1RM3 A;  4PG4 A;  3QVS A;  2GD1 O;  1RM4 A;  4H3V A;  4MVJ M;  3LC7 O;  1VSU A;  2VYV D;  2HO5 A; 
#chains in the Genus database with same CATH homology
 1I7M B;  2III A;  1I7M A;  3DZ3 B;  3H0W A;  3H0W B;  3DZ2 A;  1TLU A;  3DZ7 A;  3DZ2 B;  3EP4 A;  3EP4 B;  3DZ7 B;  3EP7 B;  3EP7 A;  3EP3 A;  3EP9 B;  3EP3 B;  3EP9 A;  1MHM A;  3EP5 B;  3EP5 A;  1MHM B;  3DZ5 A;  3DZ6 B;  1I72 A;  1I7B A;  3DZ6 A;  3DZ5 B;  1I72 B;  1JEN B;  1I7B B;  1JEN A;  3H0V B;  3H0V A;  1TMI A;  1MSV A;  1I7C B;  1I7C A;  1I79 A;  3EP8 B;  1I79 B;  3EP8 A;  1VR7 A;  1JL0 A;  3DZ4 B;  3DZ4 A;  5TVO B;  3EPB B;  5TVO A;  3EPB A;  3EP6 B;  3EPA B;  3EP6 A;  3EPA A;  3DZ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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