3H0VB

Human adometdc with 5'-deoxy-5'-(dimethylsulfonio) adenosine
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
58
Chain Sequence
HFFEGTEKLLEVWFSRQQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 8
structure length 58
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2009-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3h0vB01
3EP8B 3EPBB 1I72B 1JENB 1I7CB 1I7MB 3DZ2B 3EP5B 3DZ7B 3H0WB 5TVOB 3EPAB 3DZ3B 3DZ4B 3DZ5B 3EP4B 1I79B 3EP3B 3EP7B 3EP6B 3EP9B 1MHMB 1I7BB 3DZ6B 3H0VB
chains in the Genus database with same CATH superfamily
1T4BA 3TV1A 2HO5A 2AXQA 2XF8A 3PYLA 4GMGA 4PG7A 4II7A 1VKOA 1H6BA 1YDWA 3WGZA 5JY6A 4R5MA 4HADA 3IDSA 3WYBA 2HKIA 4WNCA 1NX6A 3DOCA 3JSAA 3B20A 3IWCB 3DZ4B 4LRSB 2HJSA 3EP3B 2X5JO 1P1IA 3BTSA 3E18A 5JYAA 3UW3A 3DZ6B 3E5RA 1PQPA 4KOAA 4BOYA 1I72B 3NT2A 1LC0A 3RVDA 5GZ1A 4MVJD 1TLTA 3ZJXA 1K3TA 4MIOA 1PQUA 3DB2A 4L9RA 3DMTC 1GAEO 1RM3A 2CVOA 3O9ZA 1I32A 2EP7A 1RYEA 1DBVO 4NHEA 3TUXA 2R00C 3EZYA 2DUUA 3NTOA 3MOIA 4XR4A 1C3VA 3Q2KA 4GQAA 2YYYA 1Q2XA 3NT4A 4XQEA 1GD1O 3Q0EA 1IHXA 3E82A 2PKRA 1EVJA 2B4RO 1ML3A 4R41A 3L6OO 3GDOA 3F4LA 1GPDG 1H9BA 1P1FA 1NPTO 1U1IA 1VC2A 1YL7A 3HQ4O 3OA2A 1H2HA 4LSMA 1JKIA 4DIBA 2DAPA 1DC4A 1EBUA 3WB9A 1JKFA 3VAZA 4DPLA 1DC5A 4R5HA 3H0WB 3PQVA 5A03A 2POQX 1QMIA 1I79B 2IXAA 2DC1A 3PWSA 4O8JA 3Q1LA 3DMTA 1DC6A 1VKNA 1UYJA 3DBVO 4ZICA 5KVSA 3NT5A 1JENB 3INGA 2H63A 3FHLA 1QKIA 2R00A 3U3XA 4JN6B 1VSVA 1TB4A 5EINA 5C7LO 3KSZO 4MKXA 4MKZA 2OZPA 3MZ0A 5J9GA 3CINA 3PZRA 4ZHSA 3HNPA 3TUTA 4PG6A 3VOSA 1P9LA 5JYFA 5A02A 2I3AA 3OHSX 2FPNA 5C7IO 1GYQA 1ARZA 4MVJM 3B1KA 4MINA 5A04A 3LC7O 2O4UX 4PG5A 3CPSA 1NWCA 3L0DA 3LVFO 3E6AA 2VYND 4INAA 3B1JA 1YWGO 2I3GA 3C1AA 1GL3A 2BH9A 3IJPA 3V1YA 1PU2A 1A7KA 3PZBA 5TVOB 5JW6A 4MVJA 1FF9A 3DZ5B 1Q7GA 1HDGO 4XB1A 2G17A 1H6DA 1MHMB 1GR0A 2BHLA 1GADO 2GLXA 1J5PA 4PG8A 1RM5A 3TZ6A 1DRUA 2GYYA 3ABIA 3DO5A 4XB2A 3NTQA 4YDRA 1H94A 3KV3O 1I7MB 1P1KA 1RYDA 3EUWA 1U8FO 3DZ2B 4HKTA 1H9AA 1OFGA 2EJWA 3PFWO 5GZ3A 3DZ3B 4L8VA 3WBFA 3L4SO 1DAPA 3HXLA 2DBVO 3MTJA 4DBVO 5A06A 3H0VB 2B4TO 3H9EO 3K9QO 4LRTB 3EPBB 4R4JA 1EBFA 1E5QA 3BTUA 2X0NA 1TA4A 3NTRA 1SZJG 2GZ3A 3QY9A 3E9MA 1TVEA 5C7OO 1DC3A 5AQ1A 4R3NA 5M6DA 1PS8A 4P8RA 5AVOA 3DAPA 2GZ2A 1OBFO 3HJAA 4IQ8A 1F06A 3CMCO 4H3VA 1OZAA 3EC7A 4IQ0A 3WGOA 4R54A 1CERA 4RL6A 3CEAA 2G82A 3PWKA 4MVJI 1E7YA 5BNTA 1QMHA 3DR3A 3OA0A 2YV3A 3ZCXA 2GD1O 1NQ5A 3EP9B 2GZ1A 1ZH8A 4MVJE 4QX6A 5A05A 3IWBB 1DPGA 3BTVA 5KVQA 5EIOA 4DPKA 1JN0A 4WNIA 2QZ9A 2CZCA 1ZNQO 1I7CB 4GPD1 5T73A 1MB4A 3RCBA 1B7GO 1DRWA 1I33A 4FB5A 4R3WA 4O89A 3IP3A 4EW6A 4Z0HO 3QVTA 3IWDB 4O59O 1I7BB 1H93A 4MVJF 3RC1A 4XQGA 4WOJA 1RM0A 1DRVA 3WYCA 1NWHA 3QVXA 1LA2A 2I5PO 2VYNA 3RC2A 3DZ7B 4CLQA 2Q4EA 1CRWG 1YS4A 1GCUA 3C8MA 3QVWA 3KGDA 4TVBA 1GYPA 4MVJG 3EP8B 3PYXA 1J0XO 1VM6A 5GZ6A 1CF2O 4XRGA 1T4DA 1BRMA 3QV1A 3EVNA 3RC9A 2PKQO 1MC4A 2P2SA 2IXBA 3QW2A 1XYGA 3EPAB 3QVSA 3WGQA 3EP4B 4MIEA 4DPMA 1IHYA 2Q22A 1PR3A 2VYVD 3BIOA 3STHA 3LC2O 1P1HA 1P1JA 1RM4A 4YWJA 2VYVA 3V5NA 3FD8A 3WGYA 2NQTA 5DDIP 4K9DA 1NQOA 3M2TA 3DTYA 2X5KO 4LGVA 5EERA 1VSUA 3ZDFA 1H6CA 3UUWA 1S7CA 3E1KA 1DSSG 3TW3A 3K2BA 4R51A 3KUXA 2D2IA 3EP7B 3Q11A 3RC7A 1NVMB 4O63O 1H6AA 3WBBA 4PG4A 3PYMA 1NBOA 3OQBA 1E5LA 4PLPA 2PKQP 3GNQA 1QXSA 1XEAA 4GMFA 3CIFA 2Q49A 4AK1A 1YL6A 2EP5A 4MVJP 4F3YA 4MJLA 2O48X 1NQAO 3V2UA 1E7MA 4MIYA 2PH5A 4XQ9A 3KSDO 3K73O 3HSKA 3LC1O 3GFGA 1LC3A 3EP5B 1DIHA 3I23A 2DPGA 1YL5A 4N54A 5CEFA 3GPDG 5JYEA 4XQCA 2NVWA 4MVJH 3Q2IA 3EP6B 5EESA 3RBVA 1E77A
chains in the Genus database with same CATH topology
1I7CA 1I7MA 1TLUA 3EP8B 1VR7A 1MSVA 3EPBB 3DZ2A 1I72B 3EP5A 1JENB 3DZ7A 3H0WA 5TVOA 1I7CB 3EPAA 1I7MB 2IIIA 3DZ3A 3EP4A 3DZ4A 3DZ5A 1I79A 1TMIA 3DZ2B 3EP3A 3EP7A 3EP5B 1JL0A 3EP6A 3EP9A 3DZ7B 1MHMA 1I7BA 3H0WB 5TVOB 3DZ6A 3H0VA 3EPAB 3DZ3B 3DZ4B 3DZ5B 3EP4B 3EP8A 1I79B 3EPBA 3EP3B 3EP7B 3EP6B 3EP9B 1I72A 1I7BB 1MHMB 1JENA 3DZ6B 3H0VB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP8 B;  3EPB B;  1I72 B;  1JEN B;  1I7C B;  1I7M B;  3DZ2 B;  3EP5 B;  3DZ7 B;  3H0W B;  5TVO B;  3EPA B;  3DZ3 B;  3DZ4 B;  3DZ5 B;  3EP4 B;  1I79 B;  3EP3 B;  3EP7 B;  3EP6 B;  3EP9 B;  1MHM B;  1I7B B;  3DZ6 B;  3H0V B; 
#chains in the Genus database with same CATH topology
 1T4B A;  3TV1 A;  2HO5 A;  2AXQ A;  2XF8 A;  3PYL A;  4GMG A;  4PG7 A;  4II7 A;  1VKO A;  1H6B A;  1YDW A;  3WGZ A;  5JY6 A;  4R5M A;  4HAD A;  3IDS A;  3WYB A;  2HKI A;  4WNC A;  1NX6 A;  3DOC A;  3JSA A;  3B20 A;  3IWC B;  3DZ4 B;  4LRS B;  2HJS A;  3EP3 B;  2X5J O;  1P1I A;  3BTS A;  3E18 A;  5JYA A;  3UW3 A;  3DZ6 B;  3E5R A;  1PQP A;  4KOA A;  4BOY A;  1I72 B;  3NT2 A;  1LC0 A;  3RVD A;  5GZ1 A;  4MVJ D;  1TLT A;  3ZJX A;  1K3T A;  4MIO A;  1PQU A;  3DB2 A;  4L9R A;  3DMT C;  1GAE O;  1RM3 A;  2CVO A;  3O9Z A;  1I32 A;  2EP7 A;  1RYE A;  1DBV O;  4NHE A;  3TUX A;  2R00 C;  3EZY A;  2DUU A;  3NTO A;  3MOI A;  4XR4 A;  1C3V A;  3Q2K A;  4GQA A;  2YYY A;  1Q2X A;  3NT4 A;  4XQE A;  1GD1 O;  3Q0E A;  1IHX A;  3E82 A;  2PKR A;  1EVJ A;  2B4R O;  1ML3 A;  4R41 A;  3L6O O;  3GDO A;  3F4L A;  1GPD G;  1H9B A;  1P1F A;  1NPT O;  1U1I A;  1VC2 A;  1YL7 A;  3HQ4 O;  3OA2 A;  1H2H A;  4LSM A;  1JKI A;  4DIB A;  2DAP A;  1DC4 A;  1EBU A;  3WB9 A;  1JKF A;  3VAZ A;  4DPL A;  1DC5 A;  4R5H A;  3H0W B;  3PQV A;  5A03 A;  2POQ X;  1QMI A;  1I79 B;  2IXA A;  2DC1 A;  3PWS A;  4O8J A;  3Q1L A;  3DMT A;  1DC6 A;  1VKN A;  1UYJ A;  3DBV O;  4ZIC A;  5KVS A;  3NT5 A;  1JEN B;  3ING A;  2H63 A;  3FHL A;  1QKI A;  2R00 A;  3U3X A;  4JN6 B;  1VSV A;  1TB4 A;  5EIN A;  5C7L O;  3KSZ O;  4MKX A;  4MKZ A;  2OZP A;  3MZ0 A;  5J9G A;  3CIN A;  3PZR A;  4ZHS A;  3HNP A;  3TUT A;  4PG6 A;  3VOS A;  1P9L A;  5JYF A;  5A02 A;  2I3A A;  3OHS X;  2FPN A;  5C7I O;  1GYQ A;  1ARZ A;  4MVJ M;  3B1K A;  4MIN A;  5A04 A;  3LC7 O;  2O4U X;  4PG5 A;  3CPS A;  1NWC A;  3L0D A;  3LVF O;  3E6A A;  2VYN D;  4INA A;  3B1J A;  1YWG O;  2I3G A;  3C1A A;  1GL3 A;  2BH9 A;  3IJP A;  3V1Y A;  1PU2 A;  1A7K A;  3PZB A;  5TVO B;  5JW6 A;  4MVJ A;  1FF9 A;  3DZ5 B;  1Q7G A;  1HDG O;  4XB1 A;  2G17 A;  1H6D A;  1MHM B;  1GR0 A;  2BHL A;  1GAD O;  2GLX A;  1J5P A;  4PG8 A;  1RM5 A;  3TZ6 A;  1DRU A;  2GYY A;  3ABI A;  3DO5 A;  4XB2 A;  3NTQ A;  4YDR A;  1H94 A;  3KV3 O;  1I7M B;  1P1K A;  1RYD A;  3EUW A;  1U8F O;  3DZ2 B;  4HKT A;  1H9A A;  1OFG A;  2EJW A;  3PFW O;  5GZ3 A;  3DZ3 B;  4L8V A;  3WBF A;  3L4S O;  1DAP A;  3HXL A;  2DBV O;  3MTJ A;  4DBV O;  5A06 A;  3H0V B;  2B4T O;  3H9E O;  3K9Q O;  4LRT B;  3EPB B;  4R4J A;  1EBF A;  1E5Q A;  3BTU A;  2X0N A;  1TA4 A;  3NTR A;  1SZJ G;  2GZ3 A;  3QY9 A;  3E9M A;  1TVE A;  5C7O O;  1DC3 A;  5AQ1 A;  4R3N A;  5M6D A;  1PS8 A;  4P8R A;  5AVO A;  3DAP A;  2GZ2 A;  1OBF O;  3HJA A;  4IQ8 A;  1F06 A;  3CMC O;  4H3V A;  1OZA A;  3EC7 A;  4IQ0 A;  3WGO A;  4R54 A;  1CER A;  4RL6 A;  3CEA A;  2G82 A;  3PWK A;  4MVJ I;  1E7Y A;  5BNT A;  1QMH A;  3DR3 A;  3OA0 A;  2YV3 A;  3ZCX A;  2GD1 O;  1NQ5 A;  3EP9 B;  2GZ1 A;  1ZH8 A;  4MVJ E;  4QX6 A;  5A05 A;  3IWB B;  1DPG A;  3BTV A;  5KVQ A;  5EIO A;  4DPK A;  1JN0 A;  4WNI A;  2QZ9 A;  2CZC A;  1ZNQ O;  1I7C B;  4GPD 1;  5T73 A;  1MB4 A;  3RCB A;  1B7G O;  1DRW A;  1I33 A;  4FB5 A;  4R3W A;  4O89 A;  3IP3 A;  4EW6 A;  4Z0H O;  3QVT A;  3IWD B;  4O59 O;  1I7B B;  1H93 A;  4MVJ F;  3RC1 A;  4XQG A;  4WOJ A;  1RM0 A;  1DRV A;  3WYC A;  1NWH A;  3QVX A;  1LA2 A;  2I5P O;  2VYN A;  3RC2 A;  3DZ7 B;  4CLQ A;  2Q4E A;  1CRW G;  1YS4 A;  1GCU A;  3C8M A;  3QVW A;  3KGD A;  4TVB A;  1GYP A;  4MVJ G;  3EP8 B;  3PYX A;  1J0X O;  1VM6 A;  5GZ6 A;  1CF2 O;  4XRG A;  1T4D A;  1BRM A;  3QV1 A;  3EVN A;  3RC9 A;  2PKQ O;  1MC4 A;  2P2S A;  2IXB A;  3QW2 A;  1XYG A;  3EPA B;  3QVS A;  3WGQ A;  3EP4 B;  4MIE A;  4DPM A;  1IHY A;  2Q22 A;  1PR3 A;  2VYV D;  3BIO A;  3STH A;  3LC2 O;  1P1H A;  1P1J A;  1RM4 A;  4YWJ A;  2VYV A;  3V5N A;  3FD8 A;  3WGY A;  2NQT A;  5DDI P;  4K9D A;  1NQO A;  3M2T A;  3DTY A;  2X5K O;  4LGV A;  5EER A;  1VSU A;  3ZDF A;  1H6C A;  3UUW A;  1S7C A;  3E1K A;  1DSS G;  3TW3 A;  3K2B A;  4R51 A;  3KUX A;  2D2I A;  3EP7 B;  3Q11 A;  3RC7 A;  1NVM B;  4O63 O;  1H6A A;  3WBB A;  4PG4 A;  3PYM A;  1NBO A;  3OQB A;  1E5L A;  4PLP A;  2PKQ P;  3GNQ A;  1QXS A;  1XEA A;  4GMF A;  3CIF A;  2Q49 A;  4AK1 A;  1YL6 A;  2EP5 A;  4MVJ P;  4F3Y A;  4MJL A;  2O48 X;  1NQA O;  3V2U A;  1E7M A;  4MIY A;  2PH5 A;  4XQ9 A;  3KSD O;  3K73 O;  3HSK A;  3LC1 O;  3GFG A;  1LC3 A;  3EP5 B;  1DIH A;  3I23 A;  2DPG A;  1YL5 A;  4N54 A;  5CEF A;  3GPD G;  5JYE A;  4XQC A;  2NVW A;  4MVJ H;  3Q2I A;  3EP6 B;  5EES A;  3RBV A;  1E77 A; 
#chains in the Genus database with same CATH homology
 1I7C A;  1I7M A;  1TLU A;  3EP8 B;  1VR7 A;  1MSV A;  3EPB B;  3DZ2 A;  1I72 B;  3EP5 A;  1JEN B;  3DZ7 A;  3H0W A;  5TVO A;  1I7C B;  3EPA A;  1I7M B;  2III A;  3DZ3 A;  3EP4 A;  3DZ4 A;  3DZ5 A;  1I79 A;  1TMI A;  3DZ2 B;  3EP3 A;  3EP7 A;  3EP5 B;  1JL0 A;  3EP6 A;  3EP9 A;  3DZ7 B;  1MHM A;  1I7B A;  3H0W B;  5TVO B;  3DZ6 A;  3H0V A;  3EPA B;  3DZ3 B;  3DZ4 B;  3DZ5 B;  3EP4 B;  3EP8 A;  1I79 B;  3EPB A;  3EP3 B;  3EP7 B;  3EP6 B;  3EP9 B;  1I72 A;  1I7B B;  1MHM B;  1JEN A;  3DZ6 B;  3H0V B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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