3EP6B

Human adometdc d174n mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSRGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 57
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep6B01
1I79B 1JENB 3EP5B 3EP9B 3EP8B 3EPAB 1I7CB 1I7BB 1MHMB 3H0WB 3DZ4B 1I7MB 3EP7B 3DZ7B 3EP3B 3DZ5B 5TVOB 3DZ2B 1I72B 3H0VB 3DZ6B 3DZ3B 3EP4B 3EPBB 3EP6B
chains in the Genus database with same CATH superfamily
3RC7A 1DBVO 1JENB 3EP9B 1DRUA 1H9BA 1U1IA 3HNPA 3NTOA 4MIYA 1IHYA 4R41A 1OZAA 4R54A 1UYJA 4PG7A 3DBVO 1PU2A 4XR4A 3K2BA 4R3NA 3L0DA 1DC4A 5EERA 1P1IA 3OQBA 4H3VA 4MJLA 3EP3B 3E5RA 1VM6A 4F3YA 3DZ5B 3Q2KA 3L6OO 4P8RA 3PZRA 1T4DA 3WB9A 3RBVA 3EPBB 3Q11A 1TA4A 4PLPA 3STHA 3NT4A 4K9DA 1K3TA 2POQX 3ZCXA 1I33A 4MKXA 1P1JA 1E7MA 3DTYA 5GZ3A 4WOJA 1NPTO 4XB1A 3Q1LA 5EINA 3HSKA 3Q2IA 1LA2A 2HO5A 2EP7A 1ML3A 3RC2A 1I79B 2X0NA 2R00A 3EP5B 3QW2A 4PG5A 3PFWO 3EP8B 1P9LA 1GCUA 2DC1A 4L9RA 3NT5A 1A7KA 3EUWA 3DOCA 3KV3O 5C7IO 4PG4A 4R3WA 1I7MB 4R51A 2HJSA 1DPGA 2VYND 3B1JA 2X5JO 3DZ2B 3LVFO 3WYBA 1MC4A 3EP4B 3K9QO 5CEFA 3EP6B 3RC1A 4HADA 1P1KA 1DC5A 3E18A 1YL5A 3GFGA 3EPAB 1P1HA 2GD1O 2YYYA 2Q22A 4MVJH 1TVEA 5KVSA 4R4JA 4GMFA 1SZJG 2XF8A 1P1FA 1GR0A 2CZCA 4INAA 2D2IA 2H63A 2EP5A 2I5PO 1TLTA 1NBOA 3OA2A 5A02A 4L8VA 4O89A 3IWBB 4MVJD 3LC2O 3UUWA 2PKRA 1F06A 3MZ0A 2BHLA 1VSUA 3TV1A 4KOAA 4Z0HO 3DMTC 1GADO 1Q7GA 3K73O 1CRWG 1I7CB 5JYAA 1RM4A 1J5PA 3QVTA 3TUXA 1YL7A 1H6CA 1S7CA 3ZJXA 5EIOA 1DRWA 1GD1O 3H0VB 5J9GA 3PYMA 3MOIA 1E77A 3QV1A 3KSZO 4YDRA 3TZ6A 4ZHSA 5GZ6A 2I3AA 3V5NA 3V1YA 5JYFA 1GPDG 5A04A 3E9MA 3IP3A 3IWDB 4MVJG 5A05A 3OA0A 4ZICA 1XYGA 1RYEA 3H0WB 1NX6A 4XRGA 1RYDA 2Q4EA 1T4BA 3UW3A 3VAZA 1HDGO 3IJPA 3C8MA 4MIOA 2R00C 2AXQA 1BRMA 1TB4A 3IWCB 5BNTA 4HKTA 3HJAA 4DPLA 3WYCA 3ABIA 1NWCA 3KSDO 3EVNA 3GDOA 4AK1A 2P2SA 1JKFA 3CPSA 3NT2A 1YDWA 1JKIA 4DIBA 3C1AA 2BH9A 3WGYA 3O9ZA 3CMCO 1YS4A 2PKQP 3MTJA 4MINA 1PS8A 3H9EO 1LC3A 2O48X 3TW3A 2CVOA 4MVJA 5DDIP 1H9AA 2X5KO 2G17A 3WGQA 1GYQA 1NQ5A 4IQ8A 1J0XO 1NQOA 4JN6B 1QKIA 1MHMB 4LSMA 4MIEA 3DZ4B 1XEAA 3CINA 3DO5A 1H2HA 4WNCA 2PH5A 5JY6A 3U3XA 3L4SO 1I72B 5KVQA 3LC7O 1H93A 3WGOA 5A06A 3JSAA 4GMGA 2OZPA 1VKNA 3F4LA 3PYLA 1GAEO 3HQ4O 4YWJA 4CLQA 1LC0A 1JN0A 3V2UA 3DR3A 1Q2XA 5JW6A 2IXBA 4FB5A 3B1KA 1PQPA 1B7GO 1QXSA 3NTRA 4QX6A 2VYVD 2EJWA 3PWKA 1QMIA 1DRVA 4R5MA 1OBFO 1ZH8A 3PWSA 3ZDFA 4RL6A 1VC2A 3PZBA 2I3GA 3BTUA 4MVJP 3E82A 3EP7B 3M2TA 1YL6A 1OFGA 3LC1O 1DAPA 3DAPA 1DC6A 5TVOB 2DAPA 4MKZA 1I32A 3QVSA 2NQTA 1RM3A 1PQUA 3Q0EA 3BIOA 3GPDG 1RM5A 2GZ1A 2Q49A 5T73A 3I23A 4XB2A 3KGDA 1E5QA 3GNQA 1VKOA 4BOYA 1EBUA 4II7A 1QMHA 2QZ9A 2GZ3A 3DZ7B 3RC9A 4GQAA 5C7OO 1ARZA 1EVJA 2VYNA 3DZ6B 3DZ3B 5GZ1A 1H6BA 3BTSA 4N54A 2NVWA 4PG8A 1E7YA 2HKIA 5C7LO 1ZNQO 3TUTA 3WGZA 2B4RO 2PKQO 4TVBA 4XQGA 3CIFA 5EESA 1E5LA 4XQEA 4MVJM 4GPD1 1CF2O 1PR3A 5AVOA 4LGVA 2DBVO 4MVJE 1MB4A 2GLXA 2GYYA 3CEAA 4NHEA 4O8JA 4XQCA 2O4UX 4LRTB 3RCBA 3KUXA 1U8FO 4EW6A 3E6AA 3BTVA 1DSSG 1CERA 4DPKA 1RM0A 5JYEA 4IQ0A 3PYXA 3EZYA 2DUUA 2DPGA 2G82A 1GYPA 1FF9A 4LRSB 4PG6A 1C3VA 3OHSX 4R5HA 2B4TO 2VYVA 1IHXA 5A03A 4O59O 4XQ9A 1I7BB 5M6DA 1GL3A 3FD8A 3IDSA 1NWHA 2YV3A 3DB2A 3VOSA 3E1KA 4DPMA 3PQVA 3INGA 3WBFA 3NTQA 3QVXA 5AQ1A 3FHLA 4MVJF 4DBVO 3QVWA 1H6AA 3EC7A 2FPNA 2GZ2A 1H6DA 1NVMB 1YWGO 4O63O 3DMTA 1VSVA 3QY9A 1DC3A 1DIHA 3RVDA 1EBFA 2IXAA 3WBBA 1H94A 4WNIA 1NQAO 3B20A 3HXLA 4MVJI
chains in the Genus database with same CATH topology
5TVOA 1I79B 3DZ2A 3DZ5A 2IIIA 1JENB 1I72A 3DZ6A 3EP5B 3EP9B 3H0VA 1VR7A 3EP8B 3EPAB 3DZ3A 3EP4A 3EPBA 1TMIA 1I79A 3EP3A 3EP6A 3EPBB 1I7CB 1JL0A 1JENA 3EP5A 3EP9A 1I7BB 1MHMB 3H0WB 3EPAA 3EP8A 3DZ4B 1I7CA 1MSVA 1I7MB 1I7BA 1MHMA 3H0WA 3EP7B 3DZ7B 3DZ4A 3EP3B 3EP4B 3DZ5B 5TVOB 3DZ2B 1I72B 1I7MA 3EP7A 3H0VB 3DZ6B 3DZ3B 1TLUA 3DZ7A 3EP6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I79 B;  1JEN B;  3EP5 B;  3EP9 B;  3EP8 B;  3EPA B;  1I7C B;  1I7B B;  1MHM B;  3H0W B;  3DZ4 B;  1I7M B;  3EP7 B;  3DZ7 B;  3EP3 B;  3DZ5 B;  5TVO B;  3DZ2 B;  1I72 B;  3H0V B;  3DZ6 B;  3DZ3 B;  3EP4 B;  3EPB B;  3EP6 B; 
#chains in the Genus database with same CATH topology
 3RC7 A;  1DBV O;  1JEN B;  3EP9 B;  1DRU A;  1H9B A;  1U1I A;  3HNP A;  3NTO A;  4MIY A;  1IHY A;  4R41 A;  1OZA A;  4R54 A;  1UYJ A;  4PG7 A;  3DBV O;  1PU2 A;  4XR4 A;  3K2B A;  4R3N A;  3L0D A;  1DC4 A;  5EER A;  1P1I A;  3OQB A;  4H3V A;  4MJL A;  3EP3 B;  3E5R A;  1VM6 A;  4F3Y A;  3DZ5 B;  3Q2K A;  3L6O O;  4P8R A;  3PZR A;  1T4D A;  3WB9 A;  3RBV A;  3EPB B;  3Q11 A;  1TA4 A;  4PLP A;  3STH A;  3NT4 A;  4K9D A;  1K3T A;  2POQ X;  3ZCX A;  1I33 A;  4MKX A;  1P1J A;  1E7M A;  3DTY A;  5GZ3 A;  4WOJ A;  1NPT O;  4XB1 A;  3Q1L A;  5EIN A;  3HSK A;  3Q2I A;  1LA2 A;  2HO5 A;  2EP7 A;  1ML3 A;  3RC2 A;  1I79 B;  2X0N A;  2R00 A;  3EP5 B;  3QW2 A;  4PG5 A;  3PFW O;  3EP8 B;  1P9L A;  1GCU A;  2DC1 A;  4L9R A;  3NT5 A;  1A7K A;  3EUW A;  3DOC A;  3KV3 O;  5C7I O;  4PG4 A;  4R3W A;  1I7M B;  4R51 A;  2HJS A;  1DPG A;  2VYN D;  3B1J A;  2X5J O;  3DZ2 B;  3LVF O;  3WYB A;  1MC4 A;  3EP4 B;  3K9Q O;  5CEF A;  3EP6 B;  3RC1 A;  4HAD A;  1P1K A;  1DC5 A;  3E18 A;  1YL5 A;  3GFG A;  3EPA B;  1P1H A;  2GD1 O;  2YYY A;  2Q22 A;  4MVJ H;  1TVE A;  5KVS A;  4R4J A;  4GMF A;  1SZJ G;  2XF8 A;  1P1F A;  1GR0 A;  2CZC A;  4INA A;  2D2I A;  2H63 A;  2EP5 A;  2I5P O;  1TLT A;  1NBO A;  3OA2 A;  5A02 A;  4L8V A;  4O89 A;  3IWB B;  4MVJ D;  3LC2 O;  3UUW A;  2PKR A;  1F06 A;  3MZ0 A;  2BHL A;  1VSU A;  3TV1 A;  4KOA A;  4Z0H O;  3DMT C;  1GAD O;  1Q7G A;  3K73 O;  1CRW G;  1I7C B;  5JYA A;  1RM4 A;  1J5P A;  3QVT A;  3TUX A;  1YL7 A;  1H6C A;  1S7C A;  3ZJX A;  5EIO A;  1DRW A;  1GD1 O;  3H0V B;  5J9G A;  3PYM A;  3MOI A;  1E77 A;  3QV1 A;  3KSZ O;  4YDR A;  3TZ6 A;  4ZHS A;  5GZ6 A;  2I3A A;  3V5N A;  3V1Y A;  5JYF A;  1GPD G;  5A04 A;  3E9M A;  3IP3 A;  3IWD B;  4MVJ G;  5A05 A;  3OA0 A;  4ZIC A;  1XYG A;  1RYE A;  3H0W B;  1NX6 A;  4XRG A;  1RYD A;  2Q4E A;  1T4B A;  3UW3 A;  3VAZ A;  1HDG O;  3IJP A;  3C8M A;  4MIO A;  2R00 C;  2AXQ A;  1BRM A;  1TB4 A;  3IWC B;  5BNT A;  4HKT A;  3HJA A;  4DPL A;  3WYC A;  3ABI A;  1NWC A;  3KSD O;  3EVN A;  3GDO A;  4AK1 A;  2P2S A;  1JKF A;  3CPS A;  3NT2 A;  1YDW A;  1JKI A;  4DIB A;  3C1A A;  2BH9 A;  3WGY A;  3O9Z A;  3CMC O;  1YS4 A;  2PKQ P;  3MTJ A;  4MIN A;  1PS8 A;  3H9E O;  1LC3 A;  2O48 X;  3TW3 A;  2CVO A;  4MVJ A;  5DDI P;  1H9A A;  2X5K O;  2G17 A;  3WGQ A;  1GYQ A;  1NQ5 A;  4IQ8 A;  1J0X O;  1NQO A;  4JN6 B;  1QKI A;  1MHM B;  4LSM A;  4MIE A;  3DZ4 B;  1XEA A;  3CIN A;  3DO5 A;  1H2H A;  4WNC A;  2PH5 A;  5JY6 A;  3U3X A;  3L4S O;  1I72 B;  5KVQ A;  3LC7 O;  1H93 A;  3WGO A;  5A06 A;  3JSA A;  4GMG A;  2OZP A;  1VKN A;  3F4L A;  3PYL A;  1GAE O;  3HQ4 O;  4YWJ A;  4CLQ A;  1LC0 A;  1JN0 A;  3V2U A;  3DR3 A;  1Q2X A;  5JW6 A;  2IXB A;  4FB5 A;  3B1K A;  1PQP A;  1B7G O;  1QXS A;  3NTR A;  4QX6 A;  2VYV D;  2EJW A;  3PWK A;  1QMI A;  1DRV A;  4R5M A;  1OBF O;  1ZH8 A;  3PWS A;  3ZDF A;  4RL6 A;  1VC2 A;  3PZB A;  2I3G A;  3BTU A;  4MVJ P;  3E82 A;  3EP7 B;  3M2T A;  1YL6 A;  1OFG A;  3LC1 O;  1DAP A;  3DAP A;  1DC6 A;  5TVO B;  2DAP A;  4MKZ A;  1I32 A;  3QVS A;  2NQT A;  1RM3 A;  1PQU A;  3Q0E A;  3BIO A;  3GPD G;  1RM5 A;  2GZ1 A;  2Q49 A;  5T73 A;  3I23 A;  4XB2 A;  3KGD A;  1E5Q A;  3GNQ A;  1VKO A;  4BOY A;  1EBU A;  4II7 A;  1QMH A;  2QZ9 A;  2GZ3 A;  3DZ7 B;  3RC9 A;  4GQA A;  5C7O O;  1ARZ A;  1EVJ A;  2VYN A;  3DZ6 B;  3DZ3 B;  5GZ1 A;  1H6B A;  3BTS A;  4N54 A;  2NVW A;  4PG8 A;  1E7Y A;  2HKI A;  5C7L O;  1ZNQ O;  3TUT A;  3WGZ A;  2B4R O;  2PKQ O;  4TVB A;  4XQG A;  3CIF A;  5EES A;  1E5L A;  4XQE A;  4MVJ M;  4GPD 1;  1CF2 O;  1PR3 A;  5AVO A;  4LGV A;  2DBV O;  4MVJ E;  1MB4 A;  2GLX A;  2GYY A;  3CEA A;  4NHE A;  4O8J A;  4XQC A;  2O4U X;  4LRT B;  3RCB A;  3KUX A;  1U8F O;  4EW6 A;  3E6A A;  3BTV A;  1DSS G;  1CER A;  4DPK A;  1RM0 A;  5JYE A;  4IQ0 A;  3PYX A;  3EZY A;  2DUU A;  2DPG A;  2G82 A;  1GYP A;  1FF9 A;  4LRS B;  4PG6 A;  1C3V A;  3OHS X;  4R5H A;  2B4T O;  2VYV A;  1IHX A;  5A03 A;  4O59 O;  4XQ9 A;  1I7B B;  5M6D A;  1GL3 A;  3FD8 A;  3IDS A;  1NWH A;  2YV3 A;  3DB2 A;  3VOS A;  3E1K A;  4DPM A;  3PQV A;  3ING A;  3WBF A;  3NTQ A;  3QVX A;  5AQ1 A;  3FHL A;  4MVJ F;  4DBV O;  3QVW A;  1H6A A;  3EC7 A;  2FPN A;  2GZ2 A;  1H6D A;  1NVM B;  1YWG O;  4O63 O;  3DMT A;  1VSV A;  3QY9 A;  1DC3 A;  1DIH A;  3RVD A;  1EBF A;  2IXA A;  3WBB A;  1H94 A;  4WNI A;  1NQA O;  3B20 A;  3HXL A;  4MVJ I; 
#chains in the Genus database with same CATH homology
 5TVO A;  1I79 B;  3DZ2 A;  3DZ5 A;  2III A;  1JEN B;  1I72 A;  3DZ6 A;  3EP5 B;  3EP9 B;  3H0V A;  1VR7 A;  3EP8 B;  3EPA B;  3DZ3 A;  3EP4 A;  3EPB A;  1TMI A;  1I79 A;  3EP3 A;  3EP6 A;  3EPB B;  1I7C B;  1JL0 A;  1JEN A;  3EP5 A;  3EP9 A;  1I7B B;  1MHM B;  3H0W B;  3EPA A;  3EP8 A;  3DZ4 B;  1I7C A;  1MSV A;  1I7M B;  1I7B A;  1MHM A;  3H0W A;  3EP7 B;  3DZ7 B;  3DZ4 A;  3EP3 B;  3EP4 B;  3DZ5 B;  5TVO B;  3DZ2 B;  1I72 B;  1I7M A;  3EP7 A;  3H0V B;  3DZ6 B;  3DZ3 B;  1TLU A;  3DZ7 A;  3EP6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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