3EP7A

Human adometdc e256q mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
260
structure length
239
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFQTNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule keywords S-adenosylmethionine decarboxylase beta chain
molecule tags Lyase
source organism Homo sapiens
total genus 61
structure length 239
sequence length 260
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 3ep7A00
1TMIA 3DZ3A 1I7BA 5TVOA 2IIIA 3EP3A 3DZ2A 1I72A 3EP4A 3EP9A 3DZ5A 3EP5A 1I79A 1JENA 3DZ6A 1VR7A 3DZ4A 1MHMA 1I7MA 3EP6A 3H0VA 1TLUA 3EP8A 1JL0A 1I7CA 1MSVA 3EPAA 3H0WA 3EP7A 3EPBA 3DZ7A
chains in the Genus database with same CATH superfamily
1TMIA 3DZ3A 1I7BA 5TVOA 2IIIA 3EP3A 3DZ2A 1I72A 3EP4A 3EP9A 3DZ5A 3EP5A 1I79A 1JENA 3DZ6A 1VR7A 3DZ4A 1MHMA 1I7MA 3EP6A 3H0VA 1TLUA 3EP8A 1JL0A 1I7CA 1MSVA 3EPAA 3H0WA 3EP7A 3EPBA 3DZ7A
chains in the Genus database with same CATH topology
1I7BB 1TMIA 3EP3B 5TVOB 3DZ2B 1I72B 3DZ3A 1I7BA 3EP9B 3EP4B 5TVOA 2IIIA 3DZ5B 3EP3A 3DZ2A 1I72A 3EP5B 3EP4A 1I79B 3EP9A 3DZ5A 3EP5A 1JENB 1I79A 3DZ6B 3DZ4B 1MHMB 1I7MB 3EP6B 1JENA 3H0VB 3DZ6A 1VR7A 3DZ4A 1MHMA 1I7MA 3EP6A 3EP8B 3H0VA 1I7CB 3EPAB 1TLUA 3EP8A 3H0WB 1JL0A 1I7CA 3EP7B 3EPBB 3DZ7B 1MSVA 3EPAA 3H0WA 3EP7A 3EPBA 3DZ7A 3DZ3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TMI A;  3DZ3 A;  1I7B A;  5TVO A;  2III A;  3EP3 A;  3DZ2 A;  1I72 A;  3EP4 A;  3EP9 A;  3DZ5 A;  3EP5 A;  1I79 A;  1JEN A;  3DZ6 A;  1VR7 A;  3DZ4 A;  1MHM A;  1I7M A;  3EP6 A;  3H0V A;  1TLU A;  3EP8 A;  1JL0 A;  1I7C A;  1MSV A;  3EPA A;  3H0W A;  3EP7 A;  3EPB A;  3DZ7 A; 
#chains in the Genus database with same CATH topology
 1TMI A;  3DZ3 A;  1I7B A;  5TVO A;  2III A;  3EP3 A;  3DZ2 A;  1I72 A;  3EP4 A;  3EP9 A;  3DZ5 A;  3EP5 A;  1I79 A;  1JEN A;  3DZ6 A;  1VR7 A;  3DZ4 A;  1MHM A;  1I7M A;  3EP6 A;  3H0V A;  1TLU A;  3EP8 A;  1JL0 A;  1I7C A;  1MSV A;  3EPA A;  3H0W A;  3EP7 A;  3EPB A;  3DZ7 A; 
#chains in the Genus database with same CATH homology
 1I7B B;  1TMI A;  3EP3 B;  5TVO B;  3DZ2 B;  1I72 B;  3DZ3 A;  1I7B A;  3EP9 B;  3EP4 B;  5TVO A;  2III A;  3DZ5 B;  3EP3 A;  3DZ2 A;  1I72 A;  3EP5 B;  3EP4 A;  1I79 B;  3EP9 A;  3DZ5 A;  3EP5 A;  1JEN B;  1I79 A;  3DZ6 B;  3DZ4 B;  1MHM B;  1I7M B;  3EP6 B;  1JEN A;  3H0V B;  3DZ6 A;  1VR7 A;  3DZ4 A;  1MHM A;  1I7M A;  3EP6 A;  3EP8 B;  3H0V A;  1I7C B;  3EPA B;  1TLU A;  3EP8 A;  3H0W B;  1JL0 A;  1I7C A;  3EP7 B;  3EPB B;  3DZ7 B;  1MSV A;  3EPA A;  3H0W A;  3EP7 A;  3EPB A;  3DZ7 A;  3DZ3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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