3H0WA

Human adometdc with 5'-deoxy-5'-[(n-dimethyl)amino]-8-methyl-adenosine
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
259
structure length
238
Chain Sequence
SMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQKIEGFKRLDCQSAMFNDYNFVFTSFAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 60
structure length 238
sequence length 259
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2009-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.90.10 Alpha Beta 4-Layer Sandwich S-adenosylmethionine decarboxylase S-adenosylmethionine decarboxylase 3h0wA00
1I7BA 3DZ3A 1I72A 1MSVA 3EP4A 3H0WA 2IIIA 1MHMA 1TMIA 1VR7A 3DZ2A 3EPBA 1I79A 3H0VA 5TVOA 3DZ4A 3EP7A 1JL0A 3EP9A 3DZ6A 1I7MA 3EPAA 1I7CA 3DZ5A 3EP8A 3EP3A 3EP5A 1JENA 3EP6A 1TLUA 3DZ7A
chains in the Genus database with same CATH superfamily
1I7BA 3DZ3A 1I72A 1MSVA 3EP4A 3H0WA 2IIIA 1MHMA 1TMIA 1VR7A 3DZ2A 3EPBA 1I79A 3H0VA 5TVOA 3DZ4A 3EP7A 1JL0A 3EP9A 3DZ6A 1I7MA 3EPAA 1I7CA 3DZ5A 3EP8A 3EP3A 3EP5A 1JENA 3EP6A 1TLUA 3DZ7A
chains in the Genus database with same CATH topology
1I7BA 1JENB 3DZ3A 1I72A 1I7BB 3DZ7B 3EP6B 1MSVA 1I72B 3DZ3B 3EP4A 3H0WA 2IIIA 3EP5B 1MHMA 1TMIA 1VR7A 3DZ2A 3EP8B 3EP4B 3H0WB 3EPBA 1I79A 3H0VA 5TVOA 1MHMB 3DZ2B 3DZ4A 3EP7A 1JL0A 3EP9A 1I79B 5TVOB 3DZ6A 1I7MA 3EPAA 3EPBB 1I7CA 3H0VB 3DZ4B 3EP7B 3DZ5A 3DZ6B 1I7MB 3EP8A 3EPAB 3EP9B 3EP3A 3EP5A 1I7CB 1JENA 3DZ5B 3EP6A 3EP3B 1TLUA 3DZ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I7B A;  3DZ3 A;  1I72 A;  1MSV A;  3EP4 A;  3H0W A;  2III A;  1MHM A;  1TMI A;  1VR7 A;  3DZ2 A;  3EPB A;  1I79 A;  3H0V A;  5TVO A;  3DZ4 A;  3EP7 A;  1JL0 A;  3EP9 A;  3DZ6 A;  1I7M A;  3EPA A;  1I7C A;  3DZ5 A;  3EP8 A;  3EP3 A;  3EP5 A;  1JEN A;  3EP6 A;  1TLU A;  3DZ7 A; 
#chains in the Genus database with same CATH topology
 1I7B A;  3DZ3 A;  1I72 A;  1MSV A;  3EP4 A;  3H0W A;  2III A;  1MHM A;  1TMI A;  1VR7 A;  3DZ2 A;  3EPB A;  1I79 A;  3H0V A;  5TVO A;  3DZ4 A;  3EP7 A;  1JL0 A;  3EP9 A;  3DZ6 A;  1I7M A;  3EPA A;  1I7C A;  3DZ5 A;  3EP8 A;  3EP3 A;  3EP5 A;  1JEN A;  3EP6 A;  1TLU A;  3DZ7 A; 
#chains in the Genus database with same CATH homology
 1I7B A;  1JEN B;  3DZ3 A;  1I72 A;  1I7B B;  3DZ7 B;  3EP6 B;  1MSV A;  1I72 B;  3DZ3 B;  3EP4 A;  3H0W A;  2III A;  3EP5 B;  1MHM A;  1TMI A;  1VR7 A;  3DZ2 A;  3EP8 B;  3EP4 B;  3H0W B;  3EPB A;  1I79 A;  3H0V A;  5TVO A;  1MHM B;  3DZ2 B;  3DZ4 A;  3EP7 A;  1JL0 A;  3EP9 A;  1I79 B;  5TVO B;  3DZ6 A;  1I7M A;  3EPA A;  3EPB B;  1I7C A;  3H0V B;  3DZ4 B;  3EP7 B;  3DZ5 A;  3DZ6 B;  1I7M B;  3EP8 A;  3EPA B;  3EP9 B;  3EP3 A;  3EP5 A;  1I7C B;  1JEN A;  3DZ5 B;  3EP6 A;  3EP3 B;  1TLU A;  3DZ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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