3MGZA

Crystal structure of dhbps domain of bi-functional dhbps/gtp cyclohydrolase ii from mycobacterium tuberculosis at ph 4.0
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
206
structure length
186
Chain Sequence
MTRLDSVERAVADIAAGKAVIVIDDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
molecule tags Lyase
source organism Mycobacterium tuberculosis
total genus 60
structure length 186
sequence length 206
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mgzA00
2RIUA 2EQAA 1K4PA 4P6DA 4E1BA 1PVYA 1IEZA 1G58A 3L7VA 3LRJA 1K7JA 3H07A 1PVWA 2RISA 3MGZA 1K4LA 4FFJA 4P8JA 1K49A 4I14A 1G57A 2MX1A 3MIOA 1TKUA 4P6CA 1TKSA 3MK5A 4P6PA 1HRUA 3LQUA 1K4OA 4P8EA 1KK9A 3LS6A 1K4IA 1JCUA 1SNNA 4P77A 3AJEA
chains in the Genus database with same CATH superfamily
3VERA 2RIUA 2EQAA 1K4PA 4P6DA 4E1BA 1PVYA 3TSPA 3VESA 3VF4A 1IEZA 1G58A 3L7VA 3LRJA 3TSQA 1K7JA 3H07A 1PVWA 2RISA 3MGZA 1K4LA 4FFJA 4P8JA 3TTCA 3VETA 3VEZA 3TTFA 3VEOA 1K49A 4I14A 1G57A 3VEWA 2MX1A 3MIOA 3VENA 1TKUA 4P6CA 3VF2A 1TKSA 3MK5A 4P6PA 3VEXA 1HRUA 3LQUA 1K4OA 3TTDA 4P8EA 3VTIA 1KK9A 3LS6A 1K4IA 3VTHA 1JCUA 1SNNA 4P77A 3AJEA 3TSUA
chains in the Genus database with same CATH topology
3VERA 2RIUA 2EQAA 1K4PA 4P6DA 4E1BA 1PVYA 3TSPA 3VESA 3VF4A 1IEZA 1G58A 3L7VA 3LRJA 3TSQA 1K7JA 3H07A 1PVWA 2RISA 3MGZA 1K4LA 4FFJA 4P8JA 3TTCA 3VETA 3VEZA 3TTFA 3VEOA 1K49A 4I14A 1G57A 3VEWA 2MX1A 3MIOA 3VENA 1TKUA 4P6CA 3VF2A 1TKSA 3MK5A 4P6PA 3VEXA 1HRUA 3LQUA 1K4OA 3TTDA 4P8EA 3VTIA 1KK9A 3LS6A 1K4IA 3VTHA 1JCUA 1SNNA 4P77A 3AJEA 3TSUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RIU A;  2EQA A;  1K4P A;  4P6D A;  4E1B A;  1PVY A;  1IEZ A;  1G58 A;  3L7V A;  3LRJ A;  1K7J A;  3H07 A;  1PVW A;  2RIS A;  3MGZ A;  1K4L A;  4FFJ A;  4P8J A;  1K49 A;  4I14 A;  1G57 A;  2MX1 A;  3MIO A;  1TKU A;  4P6C A;  1TKS A;  3MK5 A;  4P6P A;  1HRU A;  3LQU A;  1K4O A;  4P8E A;  1KK9 A;  3LS6 A;  1K4I A;  1JCU A;  1SNN A;  4P77 A;  3AJE A; 
#chains in the Genus database with same CATH topology
 3VER A;  2RIU A;  2EQA A;  1K4P A;  4P6D A;  4E1B A;  1PVY A;  3TSP A;  3VES A;  3VF4 A;  1IEZ A;  1G58 A;  3L7V A;  3LRJ A;  3TSQ A;  1K7J A;  3H07 A;  1PVW A;  2RIS A;  3MGZ A;  1K4L A;  4FFJ A;  4P8J A;  3TTC A;  3VET A;  3VEZ A;  3TTF A;  3VEO A;  1K49 A;  4I14 A;  1G57 A;  3VEW A;  2MX1 A;  3MIO A;  3VEN A;  1TKU A;  4P6C A;  3VF2 A;  1TKS A;  3MK5 A;  4P6P A;  3VEX A;  1HRU A;  3LQU A;  1K4O A;  3TTD A;  4P8E A;  3VTI A;  1KK9 A;  3LS6 A;  1K4I A;  3VTH A;  1JCU A;  1SNN A;  4P77 A;  3AJE A;  3TSU A; 
#chains in the Genus database with same CATH homology
 3VER A;  2RIU A;  2EQA A;  1K4P A;  4P6D A;  4E1B A;  1PVY A;  3TSP A;  3VES A;  3VF4 A;  1IEZ A;  1G58 A;  3L7V A;  3LRJ A;  3TSQ A;  1K7J A;  3H07 A;  1PVW A;  2RIS A;  3MGZ A;  1K4L A;  4FFJ A;  4P8J A;  3TTC A;  3VET A;  3VEZ A;  3TTF A;  3VEO A;  1K49 A;  4I14 A;  1G57 A;  3VEW A;  2MX1 A;  3MIO A;  3VEN A;  1TKU A;  4P6C A;  3VF2 A;  1TKS A;  3MK5 A;  4P6P A;  3VEX A;  1HRU A;  3LQU A;  1K4O A;  3TTD A;  4P8E A;  3VTI A;  1KK9 A;  3LS6 A;  1K4I A;  3VTH A;  1JCU A;  1SNN A;  4P77 A;  3AJE A;  3TSU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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