3MGZA

Crystal structure of dhbps domain of bi-functional dhbps/gtp cyclohydrolase ii from mycobacterium tuberculosis at ph 4.0
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
206
structure length
186
Chain Sequence
MTRLDSVERAVADIAAGKAVIVIDDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
total genus 60
structure length 186
sequence length 206
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mgzA00
1K49A 3LRJA 3MK5A 4E1BA 1TKSA 2MX1A 1K7JA 1JCUA 3L7VA 3LQUA 3H07A 4P77A 1IEZA 1HRUA 2RISA 4FFJA 1SNNA 4P6DA 3MIOA 4P8JA 1PVWA 2EQAA 1K4PA 1PVYA 1K4IA 1G57A 2RIUA 1TKUA 4P6PA 4I14A 1K4LA 1K4OA 1G58A 3AJEA 4P6CA 3LS6A 1KK9A 3MGZA 4P8EA
chains in the Genus database with same CATH superfamily
1K49A 3LRJA 3MK5A 4E1BA 1TKSA 2MX1A 1K7JA 1JCUA 3L7VA 3LQUA 3H07A 4P77A 1IEZA 1HRUA 2RISA 4FFJA 3TSQA 3VEWA 3VEXA 1SNNA 3TSPA 4P6DA 3MIOA 4P8JA 3VEZA 1PVWA 2EQAA 1K4PA 3VF4A 1PVYA 1K4IA 3VF2A 1G57A 3VENA 2RIUA 1TKUA 4P6PA 4I14A 3VEOA 3VETA 1K4LA 3TTFA 3TTDA 1K4OA 3VESA 3VERA 1G58A 3AJEA 3TTCA 4P6CA 3TSUA 3LS6A 1KK9A 3MGZA 3VTIA 3VTHA 4P8EA
chains in the Genus database with same CATH topology
1K49A 3LRJA 3MK5A 4E1BA 1TKSA 2MX1A 1K7JA 1JCUA 3L7VA 3LQUA 3H07A 4P77A 1IEZA 1HRUA 2RISA 4FFJA 3TSQA 3VEWA 3VEXA 1SNNA 3TSPA 4P6DA 3MIOA 4P8JA 3VEZA 1PVWA 2EQAA 1K4PA 3VF4A 1PVYA 1K4IA 3VF2A 1G57A 3VENA 2RIUA 1TKUA 4P6PA 4I14A 3VEOA 3VETA 1K4LA 3TTFA 3TTDA 1K4OA 3VESA 3VERA 1G58A 3AJEA 3TTCA 4P6CA 3TSUA 3LS6A 1KK9A 3MGZA 3VTIA 3VTHA 4P8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K49 A;  3LRJ A;  3MK5 A;  4E1B A;  1TKS A;  2MX1 A;  1K7J A;  1JCU A;  3L7V A;  3LQU A;  3H07 A;  4P77 A;  1IEZ A;  1HRU A;  2RIS A;  4FFJ A;  1SNN A;  4P6D A;  3MIO A;  4P8J A;  1PVW A;  2EQA A;  1K4P A;  1PVY A;  1K4I A;  1G57 A;  2RIU A;  1TKU A;  4P6P A;  4I14 A;  1K4L A;  1K4O A;  1G58 A;  3AJE A;  4P6C A;  3LS6 A;  1KK9 A;  3MGZ A;  4P8E A; 
#chains in the Genus database with same CATH topology
 1K49 A;  3LRJ A;  3MK5 A;  4E1B A;  1TKS A;  2MX1 A;  1K7J A;  1JCU A;  3L7V A;  3LQU A;  3H07 A;  4P77 A;  1IEZ A;  1HRU A;  2RIS A;  4FFJ A;  3TSQ A;  3VEW A;  3VEX A;  1SNN A;  3TSP A;  4P6D A;  3MIO A;  4P8J A;  3VEZ A;  1PVW A;  2EQA A;  1K4P A;  3VF4 A;  1PVY A;  1K4I A;  3VF2 A;  1G57 A;  3VEN A;  2RIU A;  1TKU A;  4P6P A;  4I14 A;  3VEO A;  3VET A;  1K4L A;  3TTF A;  3TTD A;  1K4O A;  3VES A;  3VER A;  1G58 A;  3AJE A;  3TTC A;  4P6C A;  3TSU A;  3LS6 A;  1KK9 A;  3MGZ A;  3VTI A;  3VTH A;  4P8E A; 
#chains in the Genus database with same CATH homology
 1K49 A;  3LRJ A;  3MK5 A;  4E1B A;  1TKS A;  2MX1 A;  1K7J A;  1JCU A;  3L7V A;  3LQU A;  3H07 A;  4P77 A;  1IEZ A;  1HRU A;  2RIS A;  4FFJ A;  3TSQ A;  3VEW A;  3VEX A;  1SNN A;  3TSP A;  4P6D A;  3MIO A;  4P8J A;  3VEZ A;  1PVW A;  2EQA A;  1K4P A;  3VF4 A;  1PVY A;  1K4I A;  3VF2 A;  1G57 A;  3VEN A;  2RIU A;  1TKU A;  4P6P A;  4I14 A;  3VEO A;  3VET A;  1K4L A;  3TTF A;  3TTD A;  1K4O A;  3VES A;  3VER A;  1G58 A;  3AJE A;  3TTC A;  4P6C A;  3TSU A;  3LS6 A;  1KK9 A;  3MGZ A;  3VTI A;  3VTH A;  4P8E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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