3MGZA

Crystal structure of dhbps domain of bi-functional dhbps/gtp cyclohydrolase ii from mycobacterium tuberculosis at ph 4.0
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
206
structure length
186
Chain Sequence
MTRLDSVERAVADIAAGKAVIVIDDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
molecule tags Lyase
source organism Mycobacterium tuberculosis
total genus 60
structure length 186
sequence length 206
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mgzA00
2EQAA 3MK5A 1PVYA 1PVWA 1KK9A 1G57A 4FFJA 3LQUA 1K4PA 1K4IA 3LRJA 4P6DA 2RISA 3H07A 4P77A 1JCUA 1SNNA 4I14A 3LS6A 2MX1A 4P6CA 4P6PA 1K49A 2RIUA 1TKSA 1K4OA 3AJEA 4E1BA 3L7VA 1G58A 3MIOA 1K7JA 1TKUA 1IEZA 1HRUA 1K4LA 3MGZA 4P8JA 4P8EA
chains in the Genus database with same CATH superfamily
2EQAA 3MK5A 3TSUA 1PVYA 1PVWA 1KK9A 1G57A 4FFJA 3LQUA 1K4PA 1K4IA 3LRJA 4P6DA 2RISA 3H07A 4P77A 3VEZA 1JCUA 1SNNA 4I14A 3LS6A 2MX1A 4P6CA 4P6PA 3TTDA 3VTHA 3VEOA 3TTCA 1K49A 3VERA 2RIUA 3VENA 3TSQA 3VF2A 3VF4A 1TKSA 1K4OA 3AJEA 3VESA 4E1BA 3TSPA 3VEWA 3L7VA 1G58A 3MIOA 1K7JA 1TKUA 3VEXA 1IEZA 3TTFA 3VTIA 1HRUA 1K4LA 3MGZA 4P8JA 3VETA 4P8EA
chains in the Genus database with same CATH topology
2EQAA 3MK5A 3TSUA 1PVYA 1PVWA 1KK9A 1G57A 4FFJA 3LQUA 1K4PA 1K4IA 3LRJA 4P6DA 2RISA 3H07A 4P77A 3VEZA 1JCUA 1SNNA 4I14A 3LS6A 2MX1A 4P6CA 4P6PA 3TTDA 3VTHA 3VEOA 3TTCA 1K49A 3VERA 2RIUA 3VENA 3TSQA 3VF2A 3VF4A 1TKSA 1K4OA 3AJEA 3VESA 4E1BA 3TSPA 3VEWA 3L7VA 1G58A 3MIOA 1K7JA 1TKUA 3VEXA 1IEZA 3TTFA 3VTIA 1HRUA 1K4LA 3MGZA 4P8JA 3VETA 4P8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EQA A;  3MK5 A;  1PVY A;  1PVW A;  1KK9 A;  1G57 A;  4FFJ A;  3LQU A;  1K4P A;  1K4I A;  3LRJ A;  4P6D A;  2RIS A;  3H07 A;  4P77 A;  1JCU A;  1SNN A;  4I14 A;  3LS6 A;  2MX1 A;  4P6C A;  4P6P A;  1K49 A;  2RIU A;  1TKS A;  1K4O A;  3AJE A;  4E1B A;  3L7V A;  1G58 A;  3MIO A;  1K7J A;  1TKU A;  1IEZ A;  1HRU A;  1K4L A;  3MGZ A;  4P8J A;  4P8E A; 
#chains in the Genus database with same CATH topology
 2EQA A;  3MK5 A;  3TSU A;  1PVY A;  1PVW A;  1KK9 A;  1G57 A;  4FFJ A;  3LQU A;  1K4P A;  1K4I A;  3LRJ A;  4P6D A;  2RIS A;  3H07 A;  4P77 A;  3VEZ A;  1JCU A;  1SNN A;  4I14 A;  3LS6 A;  2MX1 A;  4P6C A;  4P6P A;  3TTD A;  3VTH A;  3VEO A;  3TTC A;  1K49 A;  3VER A;  2RIU A;  3VEN A;  3TSQ A;  3VF2 A;  3VF4 A;  1TKS A;  1K4O A;  3AJE A;  3VES A;  4E1B A;  3TSP A;  3VEW A;  3L7V A;  1G58 A;  3MIO A;  1K7J A;  1TKU A;  3VEX A;  1IEZ A;  3TTF A;  3VTI A;  1HRU A;  1K4L A;  3MGZ A;  4P8J A;  3VET A;  4P8E A; 
#chains in the Genus database with same CATH homology
 2EQA A;  3MK5 A;  3TSU A;  1PVY A;  1PVW A;  1KK9 A;  1G57 A;  4FFJ A;  3LQU A;  1K4P A;  1K4I A;  3LRJ A;  4P6D A;  2RIS A;  3H07 A;  4P77 A;  3VEZ A;  1JCU A;  1SNN A;  4I14 A;  3LS6 A;  2MX1 A;  4P6C A;  4P6P A;  3TTD A;  3VTH A;  3VEO A;  3TTC A;  1K49 A;  3VER A;  2RIU A;  3VEN A;  3TSQ A;  3VF2 A;  3VF4 A;  1TKS A;  1K4O A;  3AJE A;  3VES A;  4E1B A;  3TSP A;  3VEW A;  3L7V A;  1G58 A;  3MIO A;  1K7J A;  1TKU A;  3VEX A;  1IEZ A;  3TTF A;  3VTI A;  1HRU A;  1K4L A;  3MGZ A;  4P8J A;  3VET A;  4P8E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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