3MK5A

Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from mycobacterium tuberculosis with sulfate and zinc at ph 4.00
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
207
structure length
191
Chain Sequence
HMTRLDSVERAVADIAAGKAVIVIDDEDEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords 3,4-dihydroxy-2-butanone 4-phosphate synthase
total genus 61
structure length 191
sequence length 207
ec nomenclature ec 3.5.4.25: GTP cyclohydrolase II.
pdb deposition date 2010-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00926 DHBP_synthase 3,4-dihydroxy-2-butanone 4-phosphate synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.870.10 Alpha Beta Alpha-Beta Complex DHBP synthase DHBP synthase 3mk5A00
1PVYA 1K4OA 1K7JA 1KK9A 3L7VA 4P6CA 1G58A 1K4PA 2EQAA 3MK5A 4P77A 4FFJA 2RISA 3LRJA 1TKSA 1TKUA 4P6DA 1G57A 4P8EA 4P6PA 1HRUA 3MGZA 1K4IA 3LQUA 3AJEA 4P8JA 1SNNA 2RIUA 4I14A 1IEZA 1K4LA 1JCUA 3LS6A 2MX1A 1K49A 1PVWA 3MIOA 3H07A 4E1BA
chains in the Genus database with same CATH superfamily
1PVYA 3VF2A 3TTDA 1K4OA 3TTFA 1K7JA 1KK9A 3L7VA 4P6CA 3TSPA 3VESA 3VEWA 1G58A 3VEXA 1K4PA 3VERA 2EQAA 3MK5A 4P77A 4FFJA 2RISA 3LRJA 1TKSA 3VF4A 1TKUA 4P6DA 1G57A 3VENA 3TSQA 4P8EA 3VEZA 4P6PA 3VEOA 1HRUA 3MGZA 1K4IA 3TSUA 3LQUA 3AJEA 4P8JA 1SNNA 2RIUA 4I14A 1IEZA 3TTCA 1K4LA 1JCUA 3LS6A 2MX1A 3VTIA 1K49A 3VTHA 1PVWA 3VETA 3MIOA 3H07A 4E1BA
chains in the Genus database with same CATH topology
1PVYA 3VF2A 3TTDA 1K4OA 3TTFA 1K7JA 1KK9A 3L7VA 4P6CA 3TSPA 3VESA 3VEWA 1G58A 3VEXA 1K4PA 3VERA 2EQAA 3MK5A 4P77A 4FFJA 2RISA 3LRJA 1TKSA 3VF4A 1TKUA 4P6DA 1G57A 3VENA 3TSQA 4P8EA 3VEZA 4P6PA 3VEOA 1HRUA 3MGZA 1K4IA 3TSUA 3LQUA 3AJEA 4P8JA 1SNNA 2RIUA 4I14A 1IEZA 3TTCA 1K4LA 1JCUA 3LS6A 2MX1A 3VTIA 1K49A 3VTHA 1PVWA 3VETA 3MIOA 3H07A 4E1BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVY A;  1K4O A;  1K7J A;  1KK9 A;  3L7V A;  4P6C A;  1G58 A;  1K4P A;  2EQA A;  3MK5 A;  4P77 A;  4FFJ A;  2RIS A;  3LRJ A;  1TKS A;  1TKU A;  4P6D A;  1G57 A;  4P8E A;  4P6P A;  1HRU A;  3MGZ A;  1K4I A;  3LQU A;  3AJE A;  4P8J A;  1SNN A;  2RIU A;  4I14 A;  1IEZ A;  1K4L A;  1JCU A;  3LS6 A;  2MX1 A;  1K49 A;  1PVW A;  3MIO A;  3H07 A;  4E1B A; 
#chains in the Genus database with same CATH topology
 1PVY A;  3VF2 A;  3TTD A;  1K4O A;  3TTF A;  1K7J A;  1KK9 A;  3L7V A;  4P6C A;  3TSP A;  3VES A;  3VEW A;  1G58 A;  3VEX A;  1K4P A;  3VER A;  2EQA A;  3MK5 A;  4P77 A;  4FFJ A;  2RIS A;  3LRJ A;  1TKS A;  3VF4 A;  1TKU A;  4P6D A;  1G57 A;  3VEN A;  3TSQ A;  4P8E A;  3VEZ A;  4P6P A;  3VEO A;  1HRU A;  3MGZ A;  1K4I A;  3TSU A;  3LQU A;  3AJE A;  4P8J A;  1SNN A;  2RIU A;  4I14 A;  1IEZ A;  3TTC A;  1K4L A;  1JCU A;  3LS6 A;  2MX1 A;  3VTI A;  1K49 A;  3VTH A;  1PVW A;  3VET A;  3MIO A;  3H07 A;  4E1B A; 
#chains in the Genus database with same CATH homology
 1PVY A;  3VF2 A;  3TTD A;  1K4O A;  3TTF A;  1K7J A;  1KK9 A;  3L7V A;  4P6C A;  3TSP A;  3VES A;  3VEW A;  1G58 A;  3VEX A;  1K4P A;  3VER A;  2EQA A;  3MK5 A;  4P77 A;  4FFJ A;  2RIS A;  3LRJ A;  1TKS A;  3VF4 A;  1TKU A;  4P6D A;  1G57 A;  3VEN A;  3TSQ A;  4P8E A;  3VEZ A;  4P6P A;  3VEO A;  1HRU A;  3MGZ A;  1K4I A;  3TSU A;  3LQU A;  3AJE A;  4P8J A;  1SNN A;  2RIU A;  4I14 A;  1IEZ A;  3TTC A;  1K4L A;  1JCU A;  3LS6 A;  2MX1 A;  3VTI A;  1K49 A;  3VTH A;  1PVW A;  3VET A;  3MIO A;  3H07 A;  4E1B A; 
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