4E2KA

The structure of the s. aureus dnag rna polymerase domain
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
321
structure length
319
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords DNA primase
total genus 116
structure length 319
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4e2kA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4e2kA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4e2kA01
4EDKA 1DD9A 4EDVA 2AU3A 2Q2EA 2V1CA 4O6PB 4O6OA 4EDGA 3VDUA 4JCVA 4EDRA 3B39A 1T6T1 4EE1A 4EDTA 1VDDA 3VDPA 4E2KA 3VE5A 1EQNA 2ZBKA 5GUJA 1D3YA 1DDEA
chains in the Genus database with same CATH superfamily
2KC6A 4EDKA 1DD9A 2NSWA 4EDVA 2AU3A 2B39A 2Q2EA 2V1CA 4O6PB 2I5RA 4O6OA 1ERCA 3CU7A 2JMSA 2ERLA 2FCJA 4EDGA 3VDUA 2KK2A 4JCVA 4EDRA 3B39A 1T6T1 2NSVA 4EE1A 4EDTA 1VDDA 2LMKA 3VDPA 4E2KA 3VE5A 1EQNA 2ZBKA 3KLSA 5GUJA 1D3YA 3KXRA 1DDEA
chains in the Genus database with same CATH topology
2KC6A 4EDKA 1DD9A 2NSWA 4EDVA 2AU3A 2B39A 2Q2EA 2V1CA 4O6PB 4O6OA 1ERCA 3CU7A 2JMSA 2ERLA 4EDGA 3VDUA 2KK2A 4JCVA 4EDRA 3B39A 1T6T1 2NSVA 4EE1A 4EDTA 1VDDA 2LMKA 3VDPA 4E2KA 3VE5A 1EQNA 2ZBKA 3KLSA 5GUJA 1D3YA 3KXRA 1DDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EDK A;  1DD9 A;  4EDV A;  2AU3 A;  2Q2E A;  2V1C A;  4O6P B;  4O6O A;  4EDG A;  3VDU A;  4JCV A;  4EDR A;  3B39 A;  1T6T 1;  4EE1 A;  4EDT A;  1VDD A;  3VDP A;  4E2K A;  3VE5 A;  1EQN A;  2ZBK A;  5GUJ A;  1D3Y A;  1DDE A; 
#chains in the Genus database with same CATH topology
 2KC6 A;  4EDK A;  1DD9 A;  2NSW A;  4EDV A;  2AU3 A;  2B39 A;  2Q2E A;  2V1C A;  4O6P B;  2I5R A;  4O6O A;  1ERC A;  3CU7 A;  2JMS A;  2ERL A;  2FCJ A;  4EDG A;  3VDU A;  2KK2 A;  4JCV A;  4EDR A;  3B39 A;  1T6T 1;  2NSV A;  4EE1 A;  4EDT A;  1VDD A;  2LMK A;  3VDP A;  4E2K A;  3VE5 A;  1EQN A;  2ZBK A;  3KLS A;  5GUJ A;  1D3Y A;  3KXR A;  1DDE A; 
#chains in the Genus database with same CATH homology
 2KC6 A;  4EDK A;  1DD9 A;  2NSW A;  4EDV A;  2AU3 A;  2B39 A;  2Q2E A;  2V1C A;  4O6P B;  4O6O A;  1ERC A;  3CU7 A;  2JMS A;  2ERL A;  4EDG A;  3VDU A;  2KK2 A;  4JCV A;  4EDR A;  3B39 A;  1T6T 1;  2NSV A;  4EE1 A;  4EDT A;  1VDD A;  2LMK A;  3VDP A;  4E2K A;  3VE5 A;  1EQN A;  2ZBK A;  3KLS A;  5GUJ A;  1D3Y A;  3KXR A;  1DDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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