4EDKA

The structure of the s. aureus dnag rna polymerase domain bound to gtp and manganese
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords DNA primase
total genus 115
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edkA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edkA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edkA01
5GUJA 2ZBKA 1T6T1 4EDKA 4JCVA 1DDEA 1EQNA 4EDVA 4O6PB 3VDPA 2Q2EA 4O6OA 1D3YA 4EDRA 1VDDA 2AU3A 4EDGA 3VDUA 2V1CA 4E2KA 4EE1A 1DD9A 3B39A 4EDTA 3VE5A
chains in the Genus database with same CATH superfamily
2I5RA 5GUJA 3CU7A 3KXRA 2JMSA 2ZBKA 1T6T1 3KLSA 4EDKA 1ERCA 4JCVA 1DDEA 1EQNA 2NSVA 4EDVA 4O6PB 3VDPA 2Q2EA 4O6OA 1D3YA 4EDRA 1VDDA 2KK2A 2LMKA 2AU3A 4EDGA 3VDUA 2NSWA 2FCJA 2V1CA 4E2KA 2ERLA 4EE1A 2B39A 1DD9A 3B39A 2KC6A 4EDTA 3VE5A
chains in the Genus database with same CATH topology
5GUJA 3CU7A 3KXRA 2JMSA 2ZBKA 1T6T1 3KLSA 4EDKA 1ERCA 4JCVA 1DDEA 1EQNA 2NSVA 4EDVA 4O6PB 3VDPA 2Q2EA 4O6OA 1D3YA 4EDRA 1VDDA 2KK2A 2LMKA 2AU3A 4EDGA 3VDUA 2NSWA 2V1CA 4E2KA 2ERLA 4EE1A 2B39A 1DD9A 3B39A 2KC6A 4EDTA 3VE5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GUJ A;  2ZBK A;  1T6T 1;  4EDK A;  4JCV A;  1DDE A;  1EQN A;  4EDV A;  4O6P B;  3VDP A;  2Q2E A;  4O6O A;  1D3Y A;  4EDR A;  1VDD A;  2AU3 A;  4EDG A;  3VDU A;  2V1C A;  4E2K A;  4EE1 A;  1DD9 A;  3B39 A;  4EDT A;  3VE5 A; 
#chains in the Genus database with same CATH topology
 2I5R A;  5GUJ A;  3CU7 A;  3KXR A;  2JMS A;  2ZBK A;  1T6T 1;  3KLS A;  4EDK A;  1ERC A;  4JCV A;  1DDE A;  1EQN A;  2NSV A;  4EDV A;  4O6P B;  3VDP A;  2Q2E A;  4O6O A;  1D3Y A;  4EDR A;  1VDD A;  2KK2 A;  2LMK A;  2AU3 A;  4EDG A;  3VDU A;  2NSW A;  2FCJ A;  2V1C A;  4E2K A;  2ERL A;  4EE1 A;  2B39 A;  1DD9 A;  3B39 A;  2KC6 A;  4EDT A;  3VE5 A; 
#chains in the Genus database with same CATH homology
 5GUJ A;  3CU7 A;  3KXR A;  2JMS A;  2ZBK A;  1T6T 1;  3KLS A;  4EDK A;  1ERC A;  4JCV A;  1DDE A;  1EQN A;  2NSV A;  4EDV A;  4O6P B;  3VDP A;  2Q2E A;  4O6O A;  1D3Y A;  4EDR A;  1VDD A;  2KK2 A;  2LMK A;  2AU3 A;  4EDG A;  3VDU A;  2NSW A;  2V1C A;  4E2K A;  2ERL A;  4EE1 A;  2B39 A;  1DD9 A;  3B39 A;  2KC6 A;  4EDT A;  3VE5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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