4EDGA

The structure of the s. aureus dnag rna polymerase domain bound to atp and manganese
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
molecule tags Transferase
source organism Staphylococcus aureus
total genus 119
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edgA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edgA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edgA01
4O6PB 1VDDA 4E2KA 4EDKA 3VDPA 4EE1A 2ZBKA 4O6OA 2Q2EA 1DD9A 2AU3A 3VE5A 1EQNA 3VDUA 1T6T1 1DDEA 3B39A 4EDVA 4EDRA 4EDTA 5GUJA 1D3YA 2V1CA 4JCVA 4EDGA
chains in the Genus database with same CATH superfamily
3KLSA 2LMKA 4O6PB 1VDDA 4E2KA 4EDKA 2KC6A 2FCJA 3VDPA 4EE1A 2ZBKA 2ERLA 3CU7A 4O6OA 2Q2EA 1DD9A 2AU3A 2KK2A 3VE5A 1EQNA 2NSWA 3VDUA 1ERCA 1T6T1 1DDEA 2B39A 2I5RA 3B39A 3KXRA 4EDVA 4EDRA 2NSVA 4EDTA 5GUJA 1D3YA 2V1CA 4JCVA 4EDGA 2JMSA
chains in the Genus database with same CATH topology
3KLSA 2LMKA 4O6PB 1VDDA 4E2KA 4EDKA 2KC6A 3VDPA 4EE1A 2ZBKA 2ERLA 3CU7A 4O6OA 2Q2EA 1DD9A 2AU3A 2KK2A 3VE5A 1EQNA 2NSWA 3VDUA 1ERCA 1T6T1 1DDEA 2B39A 3B39A 3KXRA 4EDVA 4EDRA 2NSVA 4EDTA 5GUJA 1D3YA 2V1CA 4JCVA 4EDGA 2JMSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O6P B;  1VDD A;  4E2K A;  4EDK A;  3VDP A;  4EE1 A;  2ZBK A;  4O6O A;  2Q2E A;  1DD9 A;  2AU3 A;  3VE5 A;  1EQN A;  3VDU A;  1T6T 1;  1DDE A;  3B39 A;  4EDV A;  4EDR A;  4EDT A;  5GUJ A;  1D3Y A;  2V1C A;  4JCV A;  4EDG A; 
#chains in the Genus database with same CATH topology
 3KLS A;  2LMK A;  4O6P B;  1VDD A;  4E2K A;  4EDK A;  2KC6 A;  2FCJ A;  3VDP A;  4EE1 A;  2ZBK A;  2ERL A;  3CU7 A;  4O6O A;  2Q2E A;  1DD9 A;  2AU3 A;  2KK2 A;  3VE5 A;  1EQN A;  2NSW A;  3VDU A;  1ERC A;  1T6T 1;  1DDE A;  2B39 A;  2I5R A;  3B39 A;  3KXR A;  4EDV A;  4EDR A;  2NSV A;  4EDT A;  5GUJ A;  1D3Y A;  2V1C A;  4JCV A;  4EDG A;  2JMS A; 
#chains in the Genus database with same CATH homology
 3KLS A;  2LMK A;  4O6P B;  1VDD A;  4E2K A;  4EDK A;  2KC6 A;  3VDP A;  4EE1 A;  2ZBK A;  2ERL A;  3CU7 A;  4O6O A;  2Q2E A;  1DD9 A;  2AU3 A;  2KK2 A;  3VE5 A;  1EQN A;  2NSW A;  3VDU A;  1ERC A;  1T6T 1;  1DDE A;  2B39 A;  3B39 A;  3KXR A;  4EDV A;  4EDR A;  2NSV A;  4EDT A;  5GUJ A;  1D3Y A;  2V1C A;  4JCV A;  4EDG A;  2JMS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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