4EDGA

The structure of the s. aureus dnag rna polymerase domain bound to atp and manganese
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
molecule tags Transferase
source organism Staphylococcus aureus
total genus 119
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edgA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edgA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edgA01
4EDVA 4O6OA 1D3YA 4EDKA 4EDRA 2Q2EA 3VDUA 4EE1A 4JCVA 3B39A 2AU3A 1DDEA 1T6T1 4EDTA 2V1CA 4EDGA 3VDPA 1EQNA 2ZBKA 1DD9A 4O6PB 3VE5A 5GUJA 4E2KA 1VDDA
chains in the Genus database with same CATH superfamily
4EDVA 2KC6A 4O6OA 3KXRA 2NSWA 3KLSA 2NSVA 1D3YA 4EDKA 2JMSA 4EDRA 2Q2EA 3VDUA 4EE1A 1VDDA 2LMKA 3CU7A 4JCVA 3B39A 2AU3A 2FCJA 1DDEA 1T6T1 4EDTA 2KK2A 2ERLA 4EDGA 2V1CA 3VDPA 2B39A 2I5RA 1ERCA 2ZBKA 1DD9A 4O6PB 3VE5A 5GUJA 4E2KA 1EQNA
chains in the Genus database with same CATH topology
4EDVA 2KC6A 4O6OA 3KXRA 2NSWA 3KLSA 2NSVA 1D3YA 4EDKA 2JMSA 4EDRA 2Q2EA 3VDUA 4EE1A 1VDDA 2LMKA 3CU7A 4JCVA 3B39A 2AU3A 1DDEA 1T6T1 4EDTA 2KK2A 2ERLA 4EDGA 2V1CA 3VDPA 2B39A 1ERCA 2ZBKA 1DD9A 4O6PB 3VE5A 5GUJA 4E2KA 1EQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EDV A;  4O6O A;  1D3Y A;  4EDK A;  4EDR A;  2Q2E A;  3VDU A;  4EE1 A;  4JCV A;  3B39 A;  2AU3 A;  1DDE A;  1T6T 1;  4EDT A;  2V1C A;  4EDG A;  3VDP A;  1EQN A;  2ZBK A;  1DD9 A;  4O6P B;  3VE5 A;  5GUJ A;  4E2K A;  1VDD A; 
#chains in the Genus database with same CATH topology
 4EDV A;  2KC6 A;  4O6O A;  3KXR A;  2NSW A;  3KLS A;  2NSV A;  1D3Y A;  4EDK A;  2JMS A;  4EDR A;  2Q2E A;  3VDU A;  4EE1 A;  1VDD A;  2LMK A;  3CU7 A;  4JCV A;  3B39 A;  2AU3 A;  2FCJ A;  1DDE A;  1T6T 1;  4EDT A;  2KK2 A;  2ERL A;  4EDG A;  2V1C A;  3VDP A;  2B39 A;  2I5R A;  1ERC A;  2ZBK A;  1DD9 A;  4O6P B;  3VE5 A;  5GUJ A;  4E2K A;  1EQN A; 
#chains in the Genus database with same CATH homology
 4EDV A;  2KC6 A;  4O6O A;  3KXR A;  2NSW A;  3KLS A;  2NSV A;  1D3Y A;  4EDK A;  2JMS A;  4EDR A;  2Q2E A;  3VDU A;  4EE1 A;  1VDD A;  2LMK A;  3CU7 A;  4JCV A;  3B39 A;  2AU3 A;  1DDE A;  1T6T 1;  4EDT A;  2KK2 A;  2ERL A;  4EDG A;  2V1C A;  3VDP A;  2B39 A;  1ERC A;  2ZBK A;  1DD9 A;  4O6P B;  3VE5 A;  5GUJ A;  4E2K A;  1EQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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