4EDRA

The structure of the s. aureus dnag rna polymerase domain bound to utp and manganese
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
molecule tags Transferase
source organism Staphylococcus aureus
total genus 114
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edrA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edrA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edrA01
4O6PB 3VDPA 3VDUA 4EDRA 4EDTA 4JCVA 4E2KA 1EQNA 1DDEA 1DD9A 4EDKA 1VDDA 2AU3A 4O6OA 2ZBKA 1D3YA 3VE5A 2Q2EA 4EDVA 3B39A 5GUJA 2V1CA 1T6T1 4EDGA 4EE1A
chains in the Genus database with same CATH superfamily
2I5RA 4O6PB 3VDPA 3VDUA 2ERLA 2NSWA 2B39A 2LMKA 4EDRA 4EDTA 1ERCA 4JCVA 4E2KA 1EQNA 1DDEA 1DD9A 2AU3A 4EDKA 1VDDA 4O6OA 3KXRA 2ZBKA 2KC6A 1D3YA 2FCJA 3VE5A 2NSVA 2Q2EA 4EDVA 3B39A 5GUJA 2V1CA 1T6T1 3KLSA 2JMSA 2KK2A 3CU7A 4EDGA 4EE1A
chains in the Genus database with same CATH topology
4O6PB 3VDPA 3VDUA 2ERLA 2NSWA 2B39A 2LMKA 4EDRA 4EDTA 1ERCA 4JCVA 4E2KA 1EQNA 1DDEA 1DD9A 2AU3A 4EDKA 1VDDA 4O6OA 3KXRA 2ZBKA 2KC6A 1D3YA 3VE5A 2NSVA 2Q2EA 4EDVA 3B39A 5GUJA 2V1CA 1T6T1 3KLSA 2JMSA 2KK2A 3CU7A 4EDGA 4EE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O6P B;  3VDP A;  3VDU A;  4EDR A;  4EDT A;  4JCV A;  4E2K A;  1EQN A;  1DDE A;  1DD9 A;  4EDK A;  1VDD A;  2AU3 A;  4O6O A;  2ZBK A;  1D3Y A;  3VE5 A;  2Q2E A;  4EDV A;  3B39 A;  5GUJ A;  2V1C A;  1T6T 1;  4EDG A;  4EE1 A; 
#chains in the Genus database with same CATH topology
 2I5R A;  4O6P B;  3VDP A;  3VDU A;  2ERL A;  2NSW A;  2B39 A;  2LMK A;  4EDR A;  4EDT A;  1ERC A;  4JCV A;  4E2K A;  1EQN A;  1DDE A;  1DD9 A;  2AU3 A;  4EDK A;  1VDD A;  4O6O A;  3KXR A;  2ZBK A;  2KC6 A;  1D3Y A;  2FCJ A;  3VE5 A;  2NSV A;  2Q2E A;  4EDV A;  3B39 A;  5GUJ A;  2V1C A;  1T6T 1;  3KLS A;  2JMS A;  2KK2 A;  3CU7 A;  4EDG A;  4EE1 A; 
#chains in the Genus database with same CATH homology
 4O6P B;  3VDP A;  3VDU A;  2ERL A;  2NSW A;  2B39 A;  2LMK A;  4EDR A;  4EDT A;  1ERC A;  4JCV A;  4E2K A;  1EQN A;  1DDE A;  1DD9 A;  2AU3 A;  4EDK A;  1VDD A;  4O6O A;  3KXR A;  2ZBK A;  2KC6 A;  1D3Y A;  3VE5 A;  2NSV A;  2Q2E A;  4EDV A;  3B39 A;  5GUJ A;  2V1C A;  1T6T 1;  3KLS A;  2JMS A;  2KK2 A;  3CU7 A;  4EDG A;  4EE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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