4EDTA

The structure of the s. aureus dnag rna polymerase domain bound to ppgpp and manganese
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
total genus 119
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edtA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edtA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edtA01
1D3YA 4EDVA 1T6T1 3VDPA 3VE5A 4E2KA 4O6PB 4EDRA 4EDGA 4EDKA 2AU3A 4EDTA 5GUJA 1DDEA 4O6OA 4EE1A 4JCVA 1VDDA 2Q2EA 1EQNA 3VDUA 3B39A 2ZBKA 1DD9A 2V1CA
chains in the Genus database with same CATH superfamily
1D3YA 2KK2A 4EDVA 1T6T1 3VDPA 3VE5A 4E2KA 4O6PB 4EDRA 3CU7A 4EDGA 4EDKA 2AU3A 2NSVA 4EDTA 1ERCA 3KLSA 5GUJA 1DDEA 4O6OA 2FCJA 4EE1A 2NSWA 4JCVA 2ERLA 1VDDA 2Q2EA 1EQNA 2LMKA 3VDUA 3B39A 2KC6A 3KXRA 1DD9A 2B39A 2JMSA 2ZBKA 2I5RA 2V1CA
chains in the Genus database with same CATH topology
1D3YA 2KK2A 4EDVA 1T6T1 3VDPA 3VE5A 4E2KA 4O6PB 4EDRA 3CU7A 4EDGA 4EDKA 2AU3A 2NSVA 4EDTA 1ERCA 3KLSA 5GUJA 1DDEA 4O6OA 4EE1A 2NSWA 4JCVA 2ERLA 1VDDA 2Q2EA 1EQNA 2LMKA 3VDUA 3B39A 2KC6A 3KXRA 1DD9A 2B39A 2JMSA 2ZBKA 2V1CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D3Y A;  4EDV A;  1T6T 1;  3VDP A;  3VE5 A;  4E2K A;  4O6P B;  4EDR A;  4EDG A;  4EDK A;  2AU3 A;  4EDT A;  5GUJ A;  1DDE A;  4O6O A;  4EE1 A;  4JCV A;  1VDD A;  2Q2E A;  1EQN A;  3VDU A;  3B39 A;  2ZBK A;  1DD9 A;  2V1C A; 
#chains in the Genus database with same CATH topology
 1D3Y A;  2KK2 A;  4EDV A;  1T6T 1;  3VDP A;  3VE5 A;  4E2K A;  4O6P B;  4EDR A;  3CU7 A;  4EDG A;  4EDK A;  2AU3 A;  2NSV A;  4EDT A;  1ERC A;  3KLS A;  5GUJ A;  1DDE A;  4O6O A;  2FCJ A;  4EE1 A;  2NSW A;  4JCV A;  2ERL A;  1VDD A;  2Q2E A;  1EQN A;  2LMK A;  3VDU A;  3B39 A;  2KC6 A;  3KXR A;  1DD9 A;  2B39 A;  2JMS A;  2ZBK A;  2I5R A;  2V1C A; 
#chains in the Genus database with same CATH homology
 1D3Y A;  2KK2 A;  4EDV A;  1T6T 1;  3VDP A;  3VE5 A;  4E2K A;  4O6P B;  4EDR A;  3CU7 A;  4EDG A;  4EDK A;  2AU3 A;  2NSV A;  4EDT A;  1ERC A;  3KLS A;  5GUJ A;  1DDE A;  4O6O A;  4EE1 A;  2NSW A;  4JCV A;  2ERL A;  1VDD A;  2Q2E A;  1EQN A;  2LMK A;  3VDU A;  3B39 A;  2KC6 A;  3KXR A;  1DD9 A;  2B39 A;  2JMS A;  2ZBK A;  2V1C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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