4EDVA

The structure of the s. aureus dnag rna polymerase domain bound to pppgpp and manganese
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
total genus 121
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edvA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edvA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edvA01
4E2KA 4EDRA 1DD9A 3VDPA 1D3YA 2Q2EA 3VE5A 1VDDA 2V1CA 4EDTA 4O6PB 4O6OA 1DDEA 1EQNA 1T6T1 2ZBKA 3VDUA 4EDGA 4EDVA 5GUJA 2AU3A 4EDKA 3B39A 4JCVA 4EE1A
chains in the Genus database with same CATH superfamily
4E2KA 4EDRA 3CU7A 1DD9A 3VDPA 2LMKA 1D3YA 2Q2EA 3VE5A 2FCJA 1VDDA 2V1CA 4EDTA 2NSWA 1ERCA 2KC6A 4O6PB 4O6OA 1DDEA 3KLSA 1EQNA 2NSVA 1T6T1 2I5RA 2ZBKA 3KXRA 2ERLA 3VDUA 4EDGA 2JMSA 4EDVA 5GUJA 2AU3A 2B39A 4EDKA 3B39A 4JCVA 4EE1A 2KK2A
chains in the Genus database with same CATH topology
4E2KA 4EDRA 3CU7A 1DD9A 3VDPA 2LMKA 1D3YA 2Q2EA 3VE5A 1VDDA 2V1CA 4EDTA 2NSWA 1ERCA 2KC6A 4O6PB 4O6OA 1DDEA 3KLSA 1EQNA 2NSVA 1T6T1 2ZBKA 3KXRA 2ERLA 3VDUA 4EDGA 2JMSA 4EDVA 5GUJA 2AU3A 2B39A 4EDKA 3B39A 4JCVA 4EE1A 2KK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E2K A;  4EDR A;  1DD9 A;  3VDP A;  1D3Y A;  2Q2E A;  3VE5 A;  1VDD A;  2V1C A;  4EDT A;  4O6P B;  4O6O A;  1DDE A;  1EQN A;  1T6T 1;  2ZBK A;  3VDU A;  4EDG A;  4EDV A;  5GUJ A;  2AU3 A;  4EDK A;  3B39 A;  4JCV A;  4EE1 A; 
#chains in the Genus database with same CATH topology
 4E2K A;  4EDR A;  3CU7 A;  1DD9 A;  3VDP A;  2LMK A;  1D3Y A;  2Q2E A;  3VE5 A;  2FCJ A;  1VDD A;  2V1C A;  4EDT A;  2NSW A;  1ERC A;  2KC6 A;  4O6P B;  4O6O A;  1DDE A;  3KLS A;  1EQN A;  2NSV A;  1T6T 1;  2I5R A;  2ZBK A;  3KXR A;  2ERL A;  3VDU A;  4EDG A;  2JMS A;  4EDV A;  5GUJ A;  2AU3 A;  2B39 A;  4EDK A;  3B39 A;  4JCV A;  4EE1 A;  2KK2 A; 
#chains in the Genus database with same CATH homology
 4E2K A;  4EDR A;  3CU7 A;  1DD9 A;  3VDP A;  2LMK A;  1D3Y A;  2Q2E A;  3VE5 A;  1VDD A;  2V1C A;  4EDT A;  2NSW A;  1ERC A;  2KC6 A;  4O6P B;  4O6O A;  1DDE A;  3KLS A;  1EQN A;  2NSV A;  1T6T 1;  2ZBK A;  3KXR A;  2ERL A;  3VDU A;  4EDG A;  2JMS A;  4EDV A;  5GUJ A;  2AU3 A;  2B39 A;  4EDK A;  3B39 A;  4JCV A;  4EE1 A;  2KK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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