4EDVA

The structure of the s. aureus dnag rna polymerase domain bound to pppgpp and manganese
Total Genus 121
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule keywords DNA primase
total genus 121
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edvA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edvA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edvA01
4O6OA 4EDGA 5GUJA 1VDDA 1DD9A 2Q2EA 3VDUA 4EDVA 4EE1A 4EDRA 1D3YA 3VDPA 3VE5A 4EDTA 4JCVA 4E2KA 1DDEA 2AU3A 3B39A 4O6PB 1T6T1 2V1CA 2ZBKA 1EQNA 4EDKA
chains in the Genus database with same CATH superfamily
3CU7A 4O6OA 4EDGA 5GUJA 1ERCA 1VDDA 1DD9A 2Q2EA 3VDUA 2LMKA 4EDVA 4EE1A 4EDRA 1D3YA 2JMSA 3VDPA 3VE5A 4EDTA 2ERLA 2FCJA 4JCVA 4E2KA 1DDEA 2B39A 2I5RA 2KC6A 2AU3A 3B39A 2NSWA 4O6PB 1T6T1 2NSVA 3KXRA 2KK2A 2V1CA 2ZBKA 1EQNA 3KLSA 4EDKA
chains in the Genus database with same CATH topology
3CU7A 4O6OA 4EDGA 5GUJA 1ERCA 1VDDA 1DD9A 2Q2EA 3VDUA 2LMKA 4EDVA 4EE1A 4EDRA 1D3YA 2JMSA 3VDPA 3VE5A 4EDTA 2ERLA 4JCVA 4E2KA 1DDEA 2B39A 2KC6A 2AU3A 3B39A 2NSWA 4O6PB 1T6T1 2NSVA 3KXRA 2KK2A 2V1CA 2ZBKA 1EQNA 3KLSA 4EDKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O6O A;  4EDG A;  5GUJ A;  1VDD A;  1DD9 A;  2Q2E A;  3VDU A;  4EDV A;  4EE1 A;  4EDR A;  1D3Y A;  3VDP A;  3VE5 A;  4EDT A;  4JCV A;  4E2K A;  1DDE A;  2AU3 A;  3B39 A;  4O6P B;  1T6T 1;  2V1C A;  2ZBK A;  1EQN A;  4EDK A; 
#chains in the Genus database with same CATH topology
 3CU7 A;  4O6O A;  4EDG A;  5GUJ A;  1ERC A;  1VDD A;  1DD9 A;  2Q2E A;  3VDU A;  2LMK A;  4EDV A;  4EE1 A;  4EDR A;  1D3Y A;  2JMS A;  3VDP A;  3VE5 A;  4EDT A;  2ERL A;  2FCJ A;  4JCV A;  4E2K A;  1DDE A;  2B39 A;  2I5R A;  2KC6 A;  2AU3 A;  3B39 A;  2NSW A;  4O6P B;  1T6T 1;  2NSV A;  3KXR A;  2KK2 A;  2V1C A;  2ZBK A;  1EQN A;  3KLS A;  4EDK A; 
#chains in the Genus database with same CATH homology
 3CU7 A;  4O6O A;  4EDG A;  5GUJ A;  1ERC A;  1VDD A;  1DD9 A;  2Q2E A;  3VDU A;  2LMK A;  4EDV A;  4EE1 A;  4EDR A;  1D3Y A;  2JMS A;  3VDP A;  3VE5 A;  4EDT A;  2ERL A;  4JCV A;  4E2K A;  1DDE A;  2B39 A;  2KC6 A;  2AU3 A;  3B39 A;  2NSW A;  4O6P B;  1T6T 1;  2NSV A;  3KXR A;  2KK2 A;  2V1C A;  2ZBK A;  1EQN A;  3KLS A;  4EDK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...