4E2KA

The structure of the s. aureus dnag rna polymerase domain
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
321
structure length
319
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords DNA primase
total genus 116
structure length 319
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4e2kA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4e2kA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4e2kA01
4O6OA 4EE1A 1VDDA 2ZBKA 1DDEA 1D3YA 1DD9A 3B39A 4EDVA 4JCVA 2Q2EA 2AU3A 5GUJA 4EDRA 4EDGA 3VDUA 4EDKA 4O6PB 3VE5A 1EQNA 4EDTA 2V1CA 3VDPA 4E2KA 1T6T1
chains in the Genus database with same CATH superfamily
2FCJA 2KC6A 2LMKA 3KLSA 4O6OA 4EE1A 1ERCA 2JMSA 1VDDA 2NSVA 2KK2A 3KXRA 2ZBKA 1DDEA 1D3YA 1DD9A 3B39A 2I5RA 4EDVA 4JCVA 2Q2EA 2AU3A 2ERLA 5GUJA 2NSWA 3CU7A 2B39A 4EDRA 4EDGA 3VDUA 4EDKA 4O6PB 3VE5A 1EQNA 4EDTA 2V1CA 3VDPA 4E2KA 1T6T1
chains in the Genus database with same CATH topology
2KC6A 2LMKA 3KLSA 4O6OA 4EE1A 1ERCA 2JMSA 1VDDA 2NSVA 2KK2A 3KXRA 2ZBKA 1DDEA 1D3YA 1DD9A 3B39A 4EDVA 4JCVA 2Q2EA 2AU3A 2ERLA 5GUJA 2NSWA 3CU7A 2B39A 4EDRA 4EDGA 3VDUA 4EDKA 4O6PB 3VE5A 1EQNA 4EDTA 2V1CA 3VDPA 4E2KA 1T6T1
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O6O A;  4EE1 A;  1VDD A;  2ZBK A;  1DDE A;  1D3Y A;  1DD9 A;  3B39 A;  4EDV A;  4JCV A;  2Q2E A;  2AU3 A;  5GUJ A;  4EDR A;  4EDG A;  3VDU A;  4EDK A;  4O6P B;  3VE5 A;  1EQN A;  4EDT A;  2V1C A;  3VDP A;  4E2K A;  1T6T 1; 
#chains in the Genus database with same CATH topology
 2FCJ A;  2KC6 A;  2LMK A;  3KLS A;  4O6O A;  4EE1 A;  1ERC A;  2JMS A;  1VDD A;  2NSV A;  2KK2 A;  3KXR A;  2ZBK A;  1DDE A;  1D3Y A;  1DD9 A;  3B39 A;  2I5R A;  4EDV A;  4JCV A;  2Q2E A;  2AU3 A;  2ERL A;  5GUJ A;  2NSW A;  3CU7 A;  2B39 A;  4EDR A;  4EDG A;  3VDU A;  4EDK A;  4O6P B;  3VE5 A;  1EQN A;  4EDT A;  2V1C A;  3VDP A;  4E2K A;  1T6T 1; 
#chains in the Genus database with same CATH homology
 2KC6 A;  2LMK A;  3KLS A;  4O6O A;  4EE1 A;  1ERC A;  2JMS A;  1VDD A;  2NSV A;  2KK2 A;  3KXR A;  2ZBK A;  1DDE A;  1D3Y A;  1DD9 A;  3B39 A;  4EDV A;  4JCV A;  2Q2E A;  2AU3 A;  2ERL A;  5GUJ A;  2NSW A;  3CU7 A;  2B39 A;  4EDR A;  4EDG A;  3VDU A;  4EDK A;  4O6P B;  3VE5 A;  1EQN A;  4EDT A;  2V1C A;  3VDP A;  4E2K A;  1T6T 1; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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