4EDRA

The structure of the s. aureus dnag rna polymerase domain bound to utp and manganese
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords DNA primase
total genus 114
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4edrA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4edrA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4edrA01
1DD9A 3B39A 4O6OA 4EDTA 4EDRA 4JCVA 4O6PB 4EDVA 1T6T1 3VE5A 1EQNA 1D3YA 1VDDA 4E2KA 5GUJA 3VDPA 2Q2EA 4EE1A 4EDGA 1DDEA 3VDUA 2AU3A 2V1CA 2ZBKA 4EDKA
chains in the Genus database with same CATH superfamily
1DD9A 2ERLA 3B39A 2I5RA 3CU7A 2KK2A 2NSVA 4O6OA 4EDTA 4EDRA 4JCVA 2LMKA 4O6PB 4EDVA 1T6T1 3VE5A 3KLSA 2NSWA 1EQNA 1D3YA 2B39A 1ERCA 1VDDA 4E2KA 5GUJA 3VDPA 2Q2EA 4EE1A 4EDGA 1DDEA 3VDUA 3KXRA 2AU3A 2KC6A 2V1CA 2JMSA 2FCJA 2ZBKA 4EDKA
chains in the Genus database with same CATH topology
1DD9A 2ERLA 3B39A 3CU7A 2KK2A 2NSVA 4O6OA 4EDTA 4EDRA 4JCVA 2LMKA 4O6PB 4EDVA 1T6T1 3VE5A 3KLSA 2NSWA 1EQNA 1D3YA 2B39A 1ERCA 1VDDA 4E2KA 5GUJA 3VDPA 2Q2EA 4EE1A 4EDGA 1DDEA 3VDUA 3KXRA 2AU3A 2KC6A 2V1CA 2JMSA 2ZBKA 4EDKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DD9 A;  3B39 A;  4O6O A;  4EDT A;  4EDR A;  4JCV A;  4O6P B;  4EDV A;  1T6T 1;  3VE5 A;  1EQN A;  1D3Y A;  1VDD A;  4E2K A;  5GUJ A;  3VDP A;  2Q2E A;  4EE1 A;  4EDG A;  1DDE A;  3VDU A;  2AU3 A;  2V1C A;  2ZBK A;  4EDK A; 
#chains in the Genus database with same CATH topology
 1DD9 A;  2ERL A;  3B39 A;  2I5R A;  3CU7 A;  2KK2 A;  2NSV A;  4O6O A;  4EDT A;  4EDR A;  4JCV A;  2LMK A;  4O6P B;  4EDV A;  1T6T 1;  3VE5 A;  3KLS A;  2NSW A;  1EQN A;  1D3Y A;  2B39 A;  1ERC A;  1VDD A;  4E2K A;  5GUJ A;  3VDP A;  2Q2E A;  4EE1 A;  4EDG A;  1DDE A;  3VDU A;  3KXR A;  2AU3 A;  2KC6 A;  2V1C A;  2JMS A;  2FCJ A;  2ZBK A;  4EDK A; 
#chains in the Genus database with same CATH homology
 1DD9 A;  2ERL A;  3B39 A;  3CU7 A;  2KK2 A;  2NSV A;  4O6O A;  4EDT A;  4EDR A;  4JCV A;  2LMK A;  4O6P B;  4EDV A;  1T6T 1;  3VE5 A;  3KLS A;  2NSW A;  1EQN A;  1D3Y A;  2B39 A;  1ERC A;  1VDD A;  4E2K A;  5GUJ A;  3VDP A;  2Q2E A;  4EE1 A;  4EDG A;  1DDE A;  3VDU A;  3KXR A;  2AU3 A;  2KC6 A;  2V1C A;  2JMS A;  2ZBK A;  4EDK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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