4EE1A

The structure of the s. aureus dnag rna polymerase domain bound to ctp and manganese
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
321
structure length
321
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords DNA primase
total genus 117
structure length 321
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4ee1A03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4ee1A02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4ee1A01
1EQNA 4O6PB 1DD9A 4EDVA 2V1CA 5GUJA 4JCVA 1VDDA 3VDUA 4E2KA 3VE5A 2ZBKA 4EE1A 4EDTA 2AU3A 3VDPA 4O6OA 4EDGA 3B39A 2Q2EA 1T6T1 1DDEA 1D3YA 4EDKA 4EDRA
chains in the Genus database with same CATH superfamily
1EQNA 4O6PB 1DD9A 2KK2A 2NSWA 4EDVA 2V1CA 5GUJA 4JCVA 2ERLA 3KLSA 1VDDA 3VDUA 4E2KA 3VE5A 2JMSA 2ZBKA 2LMKA 2KC6A 4EE1A 4EDTA 2AU3A 2NSVA 3VDPA 2FCJA 4O6OA 3KXRA 1ERCA 2B39A 2I5RA 3CU7A 4EDGA 3B39A 2Q2EA 1T6T1 1DDEA 1D3YA 4EDKA 4EDRA
chains in the Genus database with same CATH topology
1EQNA 4O6PB 1DD9A 2KK2A 2NSWA 4EDVA 2V1CA 5GUJA 4JCVA 2ERLA 3KLSA 1VDDA 3VDUA 4E2KA 3VE5A 2JMSA 2ZBKA 2LMKA 2KC6A 4EE1A 4EDTA 2AU3A 2NSVA 3VDPA 4O6OA 3KXRA 1ERCA 2B39A 3CU7A 4EDGA 3B39A 2Q2EA 1T6T1 1DDEA 1D3YA 4EDKA 4EDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EQN A;  4O6P B;  1DD9 A;  4EDV A;  2V1C A;  5GUJ A;  4JCV A;  1VDD A;  3VDU A;  4E2K A;  3VE5 A;  2ZBK A;  4EE1 A;  4EDT A;  2AU3 A;  3VDP A;  4O6O A;  4EDG A;  3B39 A;  2Q2E A;  1T6T 1;  1DDE A;  1D3Y A;  4EDK A;  4EDR A; 
#chains in the Genus database with same CATH topology
 1EQN A;  4O6P B;  1DD9 A;  2KK2 A;  2NSW A;  4EDV A;  2V1C A;  5GUJ A;  4JCV A;  2ERL A;  3KLS A;  1VDD A;  3VDU A;  4E2K A;  3VE5 A;  2JMS A;  2ZBK A;  2LMK A;  2KC6 A;  4EE1 A;  4EDT A;  2AU3 A;  2NSV A;  3VDP A;  2FCJ A;  4O6O A;  3KXR A;  1ERC A;  2B39 A;  2I5R A;  3CU7 A;  4EDG A;  3B39 A;  2Q2E A;  1T6T 1;  1DDE A;  1D3Y A;  4EDK A;  4EDR A; 
#chains in the Genus database with same CATH homology
 1EQN A;  4O6P B;  1DD9 A;  2KK2 A;  2NSW A;  4EDV A;  2V1C A;  5GUJ A;  4JCV A;  2ERL A;  3KLS A;  1VDD A;  3VDU A;  4E2K A;  3VE5 A;  2JMS A;  2ZBK A;  2LMK A;  2KC6 A;  4EE1 A;  4EDT A;  2AU3 A;  2NSV A;  3VDP A;  4O6O A;  3KXR A;  1ERC A;  2B39 A;  3CU7 A;  4EDG A;  3B39 A;  2Q2E A;  1T6T 1;  1DDE A;  1D3Y A;  4EDK A;  4EDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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